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George J. Bosl
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Journal Articles

Abstract C51: High sensitivity of testicular germ cell tumors to PARP inhibitor olaparib alone and in combination with cisplatin

Francesca Cavallo, Grazia Graziani, Cristina Antinozzi, Raju Chaganti, George J. Bosl, Maria Jasin, Marco Barchi
Journal: Cancer Research
Cancer Res (2011) 71 (18_Supplement): C51.
https://doi.org/10.1158/1538-7445.FBCR11-C51
Published: 28 October 2014
View articletitled, Abstract C51: High sensitivity of testicular germ cell tumors to PARP inhibitor olaparib alone and in combination with cisplatin
Journal Articles

Abstract C09: Reduced proficiency in homologous recombination underlies the high sensitivity of embryonal carcinoma testicular germ cell tumors to cisplatin and poly (ADP-ribose) polymerase inhibition

Francesca Cavallo, Grazia Graziani, Cristina Antinozzi, Darren R. Feldman, Jane Houldsworth, George J. Bosl, Raju S. K. Chaganti, Mary Ellen Moynahan, Maria Jasin, Marco Barchi
Journal: Cancer Research
Cancer Res (2013) 73 (19_Supplement): C09.
https://doi.org/10.1158/1538-7445.FBCR13-C09
Published: 15 May 2014
View articletitled, Abstract C09: Reduced proficiency in homologous recombination underlies the high sensitivity of embryonal carcinoma testicular germ cell tumors to cisplatin and poly (ADP-ribose) polymerase inhibition
Journal Articles

Abstract 3410: Regulation of pluripotency and lineage differentiation in human male germ cell tumors

Nirmala Jagadish, Manjunath Kustagi, Geetu Mendiratta, Ritu Kushwaha, Mukesh Bansal, Kim R. Hyunjae, Pavel Sumazin, Mariano Alvarez, Celine Lefebvre, Agnes Viale, James E. Korkola, Jane Houldsworth, George J. Bosl, Andrea Califano, Raju SK Chaganti
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3410.
https://doi.org/10.1158/1538-7445.AM2011-3410
Published: 15 April 2011
View articletitled, Abstract 3410: Regulation of pluripotency and lineage differentiation in human male germ cell tumors
Journal Articles

Abstract 4240: Transcription factor networks that regulate pluripotency and lineage differentiation in adult human male germ cell tumors

Nirmala Jagadish, Manjunath Kustagi, Geetu Mendiratta, Ritu Kushwaha, James E. Korkola, Jane Houldsworth, Agnes Viale, Kim R. Hyunjae, Pavel Sumazin, George J. Bosl, Andrea Califano, Raju S K Chaganti
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4240.
https://doi.org/10.1158/1538-7445.AM10-4240
Published: 15 April 2010
View articletitled, Abstract 4240: Transcription factor networks that regulate pluripotency and lineage differentiation in adult human male germ cell tumors
Journal Articles

Abstract 5162: MicroRNA regulation of epidermal lineage differentiation of NT2/D1 embryonal carcinoma cells

Ritu Kushwaha, Venkata Thodima, George J. Bosl, Raju S.K Chaganti
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5162.
https://doi.org/10.1158/1538-7445.AM10-5162
Published: 15 April 2010
View articletitled, Abstract 5162: MicroRNA regulation of epidermal lineage differentiation of NT2/D1 embryonal carcinoma cells
Journal Articles

Combined genomic and expression profiling for gene discovery in adult male germ cell tumors

James E. Korkola, Sandy Heck, Jane Houldsworth, Adam B. Olshen, Victor E. Reuter, George J. Bosl, R. S K Chaganti
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 37.
Published: 15 April 2006
View articletitled, Combined genomic and expression profiling for gene discovery in adult male germ cell tumors
Journal Articles

Down-Regulation of Stem Cell Genes, Including Those in a 200-kb Gene Cluster at 12p13.31, Is Associated with In vivo Differentiation of Human Male Germ Cell Tumors

James E. Korkola, Jane Houldsworth, Rajendrakumar S.V. Chadalavada, Adam B. Olshen, Debbie Dobrzynski, Victor E. Reuter, George J. Bosl, R.S.K. Chaganti
Journal: Cancer Research
Cancer Res (2006) 66 (2): 820–827.
https://doi.org/10.1158/0008-5472.CAN-05-2445
Published: 19 January 2006
View articletitled, Down-Regulation of Stem Cell Genes, Including Those in a 200-kb Gene Cluster at 12p13.31, Is Associated with In vivo Differentiation of Human Male Germ Cell Tumors
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Includes: Supplementary data
Journal Articles

Transcriptional programs associated with extra-embryonal and embryonal differentiation of human embryonal carcinoma cells in vitro

Raj S. V. Chadalavada, James E. Korkola, Jane Houldsworth, Adam B. Olshen, George J. Bosl, Lorenz Studer, Raju S. K. Chaganti
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 481.
Published: 01 May 2005
View articletitled, Transcriptional programs associated with extra-embryonal and embryonal differentiation of human embryonal carcinoma cells in vitro
Journal Articles

Genomic and Expression Analysis of the 12p11-p12 Amplicon Using EST Arrays Identifies Two Novel Amplified and Overexpressed Genes

Véronique Bourdon, Félix Naef, Pulivarthi H. Rao, Victor Reuter, Samuel C. Mok, George J. Bosl, Sanjay Koul, Vundaralli V. V. S. Murty, Raju S. Kucherlapati, R. S. K. Chaganti
Journal: Cancer Research
Cancer Res (2002) 62 (21): 6218–6223.
Published: 01 November 2002
View articletitled, Genomic and Expression Analysis of the 12p11-p12 Amplicon Using EST Arrays Identifies Two Novel Amplified and Overexpressed Genes
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Journal Articles

Chromosomal Amplification Is Associated with Cisplatin Resistance of Human Male Germ Cell Tumors

Pulivarthi H. Rao, Jane Houldsworth, Nallasivam Palanisamy, V. V. V. S. Murty, Victor E. Reuter, Robert J. Motzer, George J. Bosl, R. S. K. Chaganti
Journal: Cancer Research
Cancer Res (1998) 58 (19): 4260–4263.
Published: 01 October 1998
View articletitled, Chromosomal Amplification Is Associated with Cisplatin Resistance of Human Male Germ Cell Tumors
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Journal Articles

Loss of Heterozygosity Identifies Multiple Sites of Allelic Deletions on Chromosome 1 in Human Male Germ Cell Tumors

Susan Mathew, V. V. V. S. Murty, George J. Bosl, R. S. K. Chaganti
Journal: Cancer Research
Cancer Res (1994) 54 (23): 6265–6269.
Published: 01 December 1994
View articletitled, Loss of Heterozygosity Identifies Multiple Sites of Allelic Deletions on Chromosome 1 in Human Male Germ Cell Tumors
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Journal Articles

Replication Error-Type Genetic Instability at 1q42–43 in Human Male Germ Cell Tumors

V. V. V. S. Murty, Rong-Guo Li, Susan Mathew, Victor E. Reuter, David L. Bronson, George J. Bosl, R. S. K. Chaganti
Journal: Cancer Research
Cancer Res (1994) 54 (15): 3983–3985.
Published: 01 August 1994
View articletitled, Replication Error-Type Genetic Instability at 1q42–43 in Human Male Germ Cell Tumors
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Journal Articles

Phase I Trial with Pharmacokinetic Analyses of High-Dose Carboplatin, Etoposide, and Cyclophosphamide with Autologous Bone Marrow Transplantation in Patients with Refractory Germ Cell Tumors

Robert J. Motzer, Subhash C. Gulati, William P. Tong, Celia Menendez-Botet, Peter Lyn, Madhu Mazumdar, Vaia Vlamis, S. Lin, George J. Bosl
Journal: Cancer Research
Cancer Res (1993) 53 (16): 3730–3735.
Published: 01 August 1993
View articletitled, Phase I Trial with Pharmacokinetic Analyses of High-Dose Carboplatin, Etoposide, and Cyclophosphamide with Autologous Bone Marrow Transplantation in Patients with Refractory Germ Cell Tumors
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Journal Articles

Phase II Trial of Suramin in Patients with Advanced Renal Cell Carcinoma: Treatment Results, Pharmacokinetics, and Tumor Growth Factor Expression

Robert J. Motzer, David M. Nanus, Paul O'Moore, Howard I. Scher, Dean F. Bajorin, Victor Reuter, William P. Tong, Jacqueline Iversen, Carl Louison, Anthony P. Albino, George J. Bosl
Journal: Cancer Research
Cancer Res (1992) 52 (20): 5775–5779.
Published: 01 October 1992
View articletitled, Phase II Trial of Suramin in Patients with Advanced Renal Cell Carcinoma: Treatment Results, Pharmacokinetics, and Tumor Growth Factor Expression
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Journal Articles

Cytogenetic Analysis of 124 Prospectively Ascertained Male Germ Cell Tumors

Eduardo Rodriguez, Susan Mathew, Victor Reuter, David H. Ilson, George J. Bosl, R. S. K. Chaganti
Journal: Cancer Research
Cancer Res (1992) 52 (8): 2285–2291.
Published: 01 April 1992
View articletitled, Cytogenetic Analysis of 124 Prospectively Ascertained Male Germ Cell Tumors
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Journal Articles

Serum Tumor Marker Half-Life during Chemotherapy Allows Early Prediction of Complete Response and Survival in Nonseminomatous Germ Cell Tumors

Guy C. Toner, Nancy L. Geller, Claire Tan, Jerome Nisselbaum, George J. Bosl
Journal: Cancer Research
Cancer Res (1990) 50 (18): 5904–5910.
Published: 01 September 1990
View articletitled, Serum Tumor Marker Half-Life during Chemotherapy Allows Early Prediction of Complete Response and Survival in Nonseminomatous Germ Cell Tumors
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Journal Articles

Blood Group-related Antigens in Human Germ Cell Tumors

Robert J. Motzer, Victor E. Reuter, Carlos Cordon-Cardo, George J. Bosl
Journal: Cancer Research
Cancer Res (1988) 48 (18): 5342–5347.
Published: 01 September 1988
View articletitled, Blood Group-related Antigens in Human Germ Cell Tumors
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Journal Articles

Stage Migration and the Increasing Proportion of Complete Responders in Patients with Advanced Germ Cell Tumors

George J. Bosl, Nancy L. Geller, Eva Y. W. Chan
Journal: Cancer Research
Cancer Res (1988) 48 (12): 3524–3527.
Published: 01 June 1988
View articletitled, Stage Migration and the Increasing Proportion of Complete Responders in Patients with Advanced Germ Cell Tumors
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Journal Articles

Pharmacokinetics of cis-Diamminedichloroplatinum(II) after Administration in Hypertonic Saline

Dean F. Bajorin, George J. Bosl, Nancy W. Alcock, Donna Niedzwiecki, Ellen Gallina, Barbara Shurgot
Journal: Cancer Research
Cancer Res (1986) 46 (11): 5969–5972.
Published: 01 November 1986
View articletitled, Pharmacokinetics of cis-Diamminedichloroplatinum(II) after Administration in Hypertonic Saline
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Journal Articles

Multivariate Analysis of Prognostic Variables in Patients with Metastatic Testicular Cancer

George J. Bosl, Nancy L. Geller, Constance Cirrincione, Nicholas J. Vogelzang, B. J. Kennedy, Willet F. Whitmore, Jr., Davor Vugrin, Howard Scher, Jerome Nisselbaum, Robert B. Golbery
Journal: Cancer Research
Cancer Res (1983) 43 (7): 3403–3407.
Published: 01 July 1983
View articletitled, Multivariate Analysis of Prognostic Variables in Patients with Metastatic Testicular Cancer
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