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Geoffrey Neale
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Journal Articles

Abstract 3612: Three aging biomarkers differentially mediate cardiotoxicity after irradiation to the heart or exposure of anthracyclines in survivors of childhood cancer

Free
Xiaoxi Meng, Tiffany Eulalio, Noel-Marie Plonski, John Easton, Heather Mulder, Emily Walker, Geoffrey Neale, Kyla Shelton, Deo Kumar Srivastava, Stephanie B. Dixon, Jinghui Zhang, Melissa M. Hudson, Kirsten K. Ness, Gregory T. Armstrong, Zhaoming Wang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3612.
https://doi.org/10.1158/1538-7445.AM2025-3612
Published: 21 April 2025
View articletitled, Abstract 3612: Three aging biomarkers differentially mediate cardiotoxicity after irradiation to the heart or exposure of anthracyclines in survivors of childhood cancer
Journal Articles

Abstract 703: Epigenome-wide analysis of DNA methylation mediators linking cancer treatments to cardiometabolic risks in survivors of childhood cancer

Free
Tiffany Eulalio, Yoonji Kim, Peggy Meng, Qian Dong, Noel-Marie Plonski, Heather Mulder, John Easton, Emily Walker, Geoffrey Neale, Deokumar Srivastava, Stephanie Dixon, Kirsten K. Ness, Melissa M. Hudson, Gregory T. Armstrong, Zhaoming Wang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 703.
https://doi.org/10.1158/1538-7445.AM2025-703
Published: 21 April 2025
View articletitled, Abstract 703: Epigenome-wide analysis of DNA methylation mediators linking cancer treatments to cardiometabolic risks in survivors of childhood cancer
Journal Articles

Abstract 6384: DNA methylation based aging biomarkers mediate the association between patient-reported symptoms and all-cause late-mortality: A report from the St. Jude Lifetime Cohort

Free
Qian Li, Yue Pan, Xijun Zhang, Noel-Marie Plonski, g Chen, Qian Dong, Kyla Shelton, John Easton, Heather Mulder, Jinghui Zhang, Geoffrey Neale, Emily Walker, Deo Kumar Srivastava, Greg T. Armstrong, Kirsten Ness, I-Chan Huang, Zhaoming Wang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6384.
https://doi.org/10.1158/1538-7445.AM2024-6384
Published: 22 March 2024
View articletitled, Abstract 6384: DNA methylation based aging biomarkers mediate the association between patient-reported symptoms and all-cause late-mortality: A report from the St. Jude Lifetime Cohort
Journal Articles

Abstract 7441: Health-Related quality of life and DNA methylation-based aging biomarkers among survivors of childhood cancer: Results from the St. Jude Lifetime Cohort

Free
Noel-Marie Plonski, Yue Pan, Cheng Chen, Qian Dong, Xijun Zhang, Nan Song, Kyla Shelton, John Easton, Heather Mulder, Jinghui Zhang, Geoffrey Neale, Emily Walker, Hui Wang, Rachel Webster, Tara Brinkman, Kevin R. Krull, Gregory T. Armstrong, Kirsten K. Ness, Melissa M. Hudson, Qin Li, I-Chan Huang, Zhaoming Wang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7441.
https://doi.org/10.1158/1538-7445.AM2024-7441
Published: 22 March 2024
View articletitled, Abstract 7441: Health-Related quality of life and DNA methylation-based aging biomarkers among survivors of childhood cancer: Results from the St. Jude Lifetime Cohort
Journal Articles

Abstract 2235: Epigenetic inflammation scores for C-Reactive protein and interleukin-6 associate with adverse cardiometabolic and cardiac outcomes among survivors of childhood cancer

Free
Qian Dong, Yan Chen, Xijun Zhang, John Easton, Heather Mulder, Emily Walker, Geoffrey Neale, Kyla Shelton, Stephanie B. Dixon, Jinghui Zhang, Gregory T. Armstrong, Melissa M. Hudson, Kirsten K. Ness, Zhaoming Wang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2235.
https://doi.org/10.1158/1538-7445.AM2024-2235
Published: 22 March 2024
View articletitled, Abstract 2235: Epigenetic inflammation scores for C-Reactive protein and interleukin-6 associate with adverse cardiometabolic and cardiac outcomes among survivors of childhood cancer
Journal Articles

Abstract 4514: Variations of blood DNA methylation associated with cancer treatment exposures among childhood cancer survivors of African ancestry

Free
Qian Dong, Sarmistha Das, Cheng Chen, John Easton, Heather L. Mulder, Emily Walker, Geoffrey Neale, Deo Kumar Srivastava, I-Chan Huang, Jinghui Zhang, Melissa M. Hudson, Leslie L. Robison, Kirsten K. Ness, Nan Song, Zhaoming Wang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4514.
https://doi.org/10.1158/1538-7445.AM2023-4514
Published: 04 April 2023
View articletitled, Abstract 4514: Variations of blood DNA methylation associated with cancer treatment exposures among childhood cancer survivors of African ancestry
Journal Articles

Abstract 3503: Racial disparity and roles of social determinants of health in epigenetic age acceleration among survivors of childhood cancer

Free
Noel-Marie Plonski, Cheng Chen, Qian Dong, Na Qin, Nan Song, John Easton, Heather Mulder, Emily Walker, Geoffrey Neale, Jinghui Zhang, Kevin Krull, Kirsten K. Ness, Melissa M. Hudson, Leslie L. Robison, I-Chan Huang, Zhaoming Wang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3503.
https://doi.org/10.1158/1538-7445.AM2023-3503
Published: 04 April 2023
View articletitled, Abstract 3503: Racial disparity and roles of social determinants of health in epigenetic age acceleration among survivors of childhood cancer
Journal Articles

Abstract 4363: Monocyte-specific epigenetic age acceleration and cardiomyopathy risk among survivors of childhood cancer

Free
Cheng Chen, Qian Dong, Qin Na, Nan Song, John Easton, Heather L. Mulder, Emily Walker, Geoffrey Neale, Emily R. Finch, Qian Li, Yutaka Yasui, Daniel A. Mulrooney, Melissa M. Hudson, Kirsten K. Ness, Jinghui Zhang, Xiang Chen, Hui Wang, Leslie L. Robison, Zhaoming Wang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4363.
https://doi.org/10.1158/1538-7445.AM2023-4363
Published: 04 April 2023
View articletitled, Abstract 4363: Monocyte-specific epigenetic age acceleration and cardiomyopathy risk among survivors of childhood cancer
Journal Articles

Abstract B017: Epigenetic age in peripheral blood among children, adolescent, and adult survivors of childhood cancer

Free
Noel-Marie Plonski, Cheng Chen, Qian Dong, Na Qin, Kyla C. Shelton, Emily Finch, John Easton, Heather Mulder, Jinghui Zhang, Geoffrey Neale, Emily Walker, Hui Wang, Kevin Krull, Kirsten K. Ness, Melissa M Hudson, Leslie L. Robinson, Qian Li, AnnaLynn Williams, Zhaoming Wang
Journal: Cancer Research
Cancer Res (2023) 83 (2_Supplement_1): B017.
https://doi.org/10.1158/1538-7445.AGCA22-B017
Published: 15 January 2023
View articletitled, Abstract B017: Epigenetic age in peripheral blood among children, adolescent, and adult survivors of childhood cancer
Journal Articles

Abstract 3764: Epigenome-wide association study of blood lipids among survivors of childhood cancer in the St. Jude Lifetime Cohort

Free
Qian Dong, Nan Song, Cheng Chen, Zhenghong Li, John Easton, Heather Mulder, Jinghui Zhang, Geoffrey Neale, Emily Walker, I-Chan Huang, Kirsten K. Ness, Melissa M. Hudson, Leslie L. Robison, Zhaoming Wang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3764.
https://doi.org/10.1158/1538-7445.AM2022-3764
Published: 15 June 2022
View articletitled, Abstract 3764: Epigenome-wide association study of blood lipids among survivors of childhood cancer in the St. Jude Lifetime Cohort
Journal Articles

Abstract CT027: Exploration of association of leukemic molecular profile with efficacy in patients (pts) with relapsed/refractory acute lymphoblastic leukemia (ALL) treated with inotuzumab ozogamicin (InO) in the phase 3 INO-VATE trial

Free
Yaqi Zhao, A Douglas Laird, Kathryn Roberts, Rolla Yafawi, Hagop Kantarjian, Daniel J. DeAngelo, Matthias Stelljes, Michaela Liedtke, Wendy Stock, Nicola Gökbuget, Susan O'Brien, Elias Jabbour, Ryan D. Cassaday, Melanie R. Loyd, Scott Olsen, Geoffrey Neale, Xueli Liu, Erik Vandendries, Charles G. Mullighan, Anjali Advani
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT027.
https://doi.org/10.1158/1538-7445.AM2022-CT027
Published: 15 June 2022
View articletitled, Abstract CT027: Exploration of association of leukemic molecular profile with efficacy in patients (pts) with relapsed/refractory acute lymphoblastic leukemia (ALL) treated with inotuzumab ozogamicin (InO) in the phase 3 INO-VATE trial
Journal Articles

Abstract 685: A social epigenomic investigation of racial disparity in pulmonary impairment among aging survivors of childhood cancer

Free
Nan Song, Jin-ah Sim, Qian Dong, Yinan Zheng, Lifang Hou, Zhenghong Li, Chia-Wei Hsu, Haitao Pan, Heather Mulder, John Easton, Emily Walker, Geoffrey Neale, Carmen L. Wilson, Kirsten K. Ness, Kevin R. Krull, Deo Kumar Srivastava, Yutaka Yasui, Jinghui Zhang, Melissa M. Hudson, Leslie L. Robison, I-Chan Huang, Zhaoming Wang
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 685.
https://doi.org/10.1158/1538-7445.AM2021-685
Published: 01 July 2021
View articletitled, Abstract 685: A social epigenomic investigation of racial disparity in pulmonary impairment among aging survivors of childhood cancer
Journal Articles

Abstract 904: Epigenome-wide association study of dyslipidemia in survivors of childhood cancer: A report from the St. Jude lifetime cohort

Free
Qian Dong, Nan Song, Yadav Sapkota, Yinan Zheng, I-Chan Huang, Deo Kumar Srivastava, John Easton, Heather Mulder, Geoffrey Neale, Emily Walker, Jinghui Zhang, Melissa M. Hudson, Leslie L. Robison, Zhaoming Wang
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 904.
https://doi.org/10.1158/1538-7445.AM2021-904
Published: 01 July 2021
View articletitled, Abstract 904: Epigenome-wide association study of dyslipidemia in survivors of childhood cancer: A report from the St. Jude lifetime cohort
Journal Articles

A MyD88/IL1R Axis Regulates PD-1 Expression on Tumor-Associated Macrophages and Sustains Their Immunosuppressive Function in Melanoma

Available to Purchase
Sarang Tartey, Geoffrey Neale, Peter Vogel, R.K. Subbarao Malireddi, Thirumala-Devi Kanneganti
Journal: Cancer Research
Cancer Res (2021) 81 (9): 2358–2372.
https://doi.org/10.1158/0008-5472.CAN-20-3510
Published: 01 May 2021
View articletitled, A MyD88/IL1R Axis Regulates PD-1 Expression on Tumor-Associated Macrophages and Sustains Their Immunosuppressive Function in Melanoma
Open the PDF for A MyD88/IL1R Axis Regulates PD-1 Expression on Tumor-Associated Macrophages and Sustains Their Immunosuppressive Function in Melanoma in another window
Includes: Supplementary data
Journal Articles

The Common Germline TP53-R337H Mutation Is Hypomorphic and Confers Incomplete Penetrance and Late Tumor Onset in a Mouse Model

Free
John R. Jeffers, Emilia M. Pinto, Jerold E. Rehg, Michael R. Clay, Jinling Wang, Geoffrey Neale, Richard J. Heath, Guillermina Lozano, Enzo Lalli, Bonald C. Figueiredo, Alberto S. Pappo, Carlos Rodriguez-Galindo, Wenan Chen, Stanley Pounds, Raul C. Ribeiro, Gerard P. Zambetti
Journal: Cancer Research
Series: Author Choice
Cancer Res (2021) 81 (9): 2442–2456.
https://doi.org/10.1158/0008-5472.CAN-20-1750
Published: 01 May 2021
View articletitled, The Common Germline TP53-R337H Mutation Is Hypomorphic and Confers Incomplete Penetrance and Late Tumor Onset in a Mouse Model
Open the PDF for The Common Germline TP53-R337H Mutation Is Hypomorphic and Confers Incomplete Penetrance and Late Tumor Onset in a Mouse Model in another window
Includes: Supplementary data
Journal Articles

Bromodomain-Selective BET Inhibitors Are Potent Antitumor Agents against MYC-Driven Pediatric Cancer

Available to Purchase
P. Jake Slavish, Liying Chi, Mi-Kyung Yun, Lyudmila Tsurkan, Nancy E. Martinez, Barbara Jonchere, Sergio C. Chai, Michele Connelly, M. Brett Waddell, Sourav Das, Geoffrey Neale, Zhenmei Li, William R. Shadrick, Rachelle R. Olsen, Kevin W. Freeman, Jonathan A. Low, Jeanine E. Price, Brandon M. Young, Nagakumar Bharatham, Vincent A. Boyd, Jun Yang, Richard E. Lee, Marie Morfouace, Martine F. Roussel, Taosheng Chen, Daniel Savic, R. Kiplin Guy, Stephen W. White, Anang A. Shelat, Philip M. Potter
Journal: Cancer Research
Cancer Res (2020) 80 (17): 3507–3518.
https://doi.org/10.1158/0008-5472.CAN-19-3934
Published: 02 September 2020
View articletitled, Bromodomain-Selective BET Inhibitors Are Potent Antitumor Agents against MYC-Driven Pediatric Cancer
Open the PDF for Bromodomain-Selective BET Inhibitors Are Potent Antitumor Agents against MYC-Driven Pediatric Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 2691: Genome-wide association study identifies two susceptibility loci that modify radiation-related risk for breast cancer after childhood cancer: A report from the Childhood Cancer Survivor Study and St. Jude Lifetime Cohort

Free
Lindsay M. Morton, Joshua N. Sampson, Gregory T. Armstrong, Ting-Huei Chen, Melissa Hudson, Eric Karlins, Casey L. Dagnall, Shenchao Li, Carmen L. Wilson, Kumar Srivastava, Wei Liu, Guolian Kang, Kevin Oeffinger, Tara O. Henderson, Chaya S. Moskowitz, Todd M. Gibson, Diana M. Merino, Jeannette R. Wong, Sue Hammond, Joseph P. Neglia, Lucie M. Turcotte, Jeremy Miller, Laura Bowen, William A. Wheeler, Wendy M. Leisenring, John A. Whitton, Laurie Burdette, Belynda D. Hicks, Mitchell J. Machiela, Aurelie Vogt, Zhaoming Wang, Meredith Yeager, Geoffrey Neale, Matthew Lear, Louise C. Strong, Yutaka Yasui, Marilyn Stovall, Rita E. Weathers, Susan A. Smith, Rebecca Howell, Stella M. Davies, Gretchen A. Radloff, Amy Berrington de González, Peter D. Inskip, Preetha Rajaraman, Joseph F. Fraumeni, Smita Bhatia, Stephen J. Chanock, Margaret A. Tucker, Leslie L. Robison
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2691.
https://doi.org/10.1158/1538-7445.AM2016-2691
Published: 15 July 2016
View articletitled, Abstract 2691: Genome-wide association study identifies two susceptibility loci that modify radiation-related risk for breast cancer after childhood cancer: A report from the Childhood Cancer Survivor Study and St. Jude Lifetime Cohort
Journal Articles

Abstract LB-341: Evolving functional heterogeneity in B-acute lymphoblastic leukemia

Free
Stephanie M. Dobson, Robert Vanner, Esmé Waanders, Olga I. Gan, Jessica McLeod, Ildiko Grandal, Debbie Payne-Turner, Michael Edmonson, Zhaohui Gu, Xioatu Ma, Yiping Fan, Pankaj Gupta, Sagi Abelson, Michael Rusch, Ying Shao, Scott Olsen, Geoffrey Neale, John Easton, Cynthia J. Guidos, Jayne S. Danska, Jinghui Zhang, Mark D. Minden, Charles G. Mullighan, John E. Dick
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-341.
https://doi.org/10.1158/1538-7445.AM2016-LB-341
Published: 15 July 2016
View articletitled, Abstract LB-341: Evolving functional heterogeneity in B-acute lymphoblastic leukemia
Journal Articles

Abstract LB-63: Cell ground state dictates cancer susceptibility across organs

Free
Liqin Zhu, Helen Poppleton, Geoffrey Neale, Arzu Onar-Thomas, Stanley Pounds, Armita Bahrami, Sarah Utley, Kasper S. Wang, Dolores H. Lopez-Terrada, David W. Ellison, Richard J. Gilbertson
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-63.
https://doi.org/10.1158/1538-7445.AM2014-LB-63
Published: 01 October 2014
View articletitled, Abstract LB-63: Cell ground state dictates cancer susceptibility across organs
Journal Articles

Abstract 2544: Potential gene variants associated with obesity following cranial radiation treatment for childhood cancer in a genome-wide association study.

Free
Carmen L. Wilson, Wei Liu, Geoffrey Neale, Deokumar Srivastava, James G. Gurney, Guolian Kang, Perdeep Mehta, Rohit Ojha, Melissa M. Hudson, Leslie L. Robison, Kirsten K. Ness
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2544.
https://doi.org/10.1158/1538-7445.AM2013-2544
Published: 15 April 2013
View articletitled, Abstract 2544: Potential gene variants associated with obesity following cranial radiation treatment for childhood cancer in a genome-wide association study.