1-11 of 11
Gene Hung
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Abstract CT239: Clinical and preclinical evidence of an immune modulating role for the STAT3-targeting ASO AZD9150 and potential to enhance clinical responses to anti-PDL1 therapy

Patricia E. Mccoon, Rich Woessner, Shaun Grosskurth, Chris Womack, Mason Yamashita, Gene Hung, Robert MacLeod, Kirsten Bell, Mike Collins, Rachel DuPont, Vivian Jacobs, Michele Johnstone, Margaret Veldman-Jones, Paul Lyne
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): CT239.
DOI: https://doi.org/10.1158/1538-7445.AM2015-CT239
Published: 01 August 2015
View article
Journal Articles

Abstract LB-227: Preclinical pharmacology and clinical efficacy of AZD9150 (ISIS-STAT3Rx), a potent next-generation antisense oligonucleotide inhibitor of STAT3

David Hong, Youngsoo Kim, Anas Younes, John Nemunaitis, Nathan Fowler, Jeff Hsu, Tianyuan Zhou, Luis Fayad, Nancy Zhang, Sarina Piha-Paul, Richard Woessner, Murali V. Nadella, Deborah Lawson, Corinne Reimer, Minji Jo, Joanna Schmidt, Xiaokun Xiao, Sarah Greenlee, Gene Hung, Mason Yamashita, David C. Blakey, Brett P. Monia, A. Robert Macleod, Razelle Kurzrock
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-227.
DOI: https://doi.org/10.1158/1538-7445.AM2014-LB-227
Published: 01 October 2014
View article
Journal Articles

Abstract LB-317: Potent in vivo pharmacology of AZD9150, a next-generation, constrained ethyl-modified antisense oligonucleotide targeting STAT3 in multiple preclinical cancer models.

Youngsoo Kim, Jeff Hsu, Tianyuan Zhou, Nancy Zhang, Richard Woessner, Murali VP Nadella, Deborah Lawson, Corinne Reimer, Guobin He, Joanna Schmidt, Xiaokun Xiao, Sarah Greenlee, Gourab Bhattacharjee, Gene Hung, Brett P. Monia, A. Robert MacLeod
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-317.
DOI: https://doi.org/10.1158/1538-7445.AM2013-LB-317
Published: 15 April 2013
View article
Journal Articles

Abstract 1121: The long non-coding RNA MALAT1 is an essential gene regulator for lung cancer metastasis in a novel human knockout model .

Tony Gutschner, Monika Hämmerle, Moritz Eißmann, Jeff Hsu, Youngsoo Kim, Gene Hung, Alexey Revenko, Gayatri Arun, Marion Stentrup, Matthias Groß, Martin Zörnig, A. Robert MacLeod, David L. Spector, Sven Diederichs
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1121.
DOI: https://doi.org/10.1158/1538-7445.AM2013-1121
Published: 15 April 2013
View article
Journal Articles

Abstract 3302: Antisense oligonucleotide depletion of the mitotic kinesin Eg5 by direct delivery to the brain could be a useful strategy for treating glioma tumors.

Cecilia C. Krona, Jihane Boubaker, Dinorah Friedmann-Morvinski, Alex Wong, Melissa McAlonis-Downes, Erich Koller, Aneeza S. Kim, Gene Hung, Frank Rigo, Seung Chun, Benjamin Vitre, Frank Bennett, Inder Verma, Don W. Cleveland
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3302.
DOI: https://doi.org/10.1158/1538-7445.AM2013-3302
Published: 15 April 2013
View article
Journal Articles

Abstract B23: Selective inhibition of a long non-coding RNA (lncRNA), MALAT1 by antisense oligonucleotides results in significant anti-tumor effects in a variety of preclinical cancer models

Jeff Hsu, Guobin He, Gourab Bhattacharjee, Tianyuan Zhou, Chris May, Xiaokun Xiao, Gene Hung, Brett P. Monia, A. Robert MacLeod, Youngsoo Kim
Journal: Cancer Research
Cancer Res (2012) 72 (2_Supplement): B23.
DOI: https://doi.org/10.1158/1538-7445.NONRNA12-B23
Published: 03 April 2013
View article
Journal Articles

The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells

Tony Gutschner, Monika Hämmerle, Moritz Eißmann, Jeff Hsu, Youngsoo Kim, Gene Hung, Alexey Revenko, Gayatri Arun, Marion Stentrup, Matthias Groß, Martin Zörnig, A. Robert MacLeod, David L. Spector, Sven Diederichs
Journal: Cancer Research
Cancer Res (2013) 73 (3): 1180–1189.
DOI: https://doi.org/10.1158/0008-5472.CAN-12-2850
Published: 31 January 2013
View article
PDF
Includes: Supplementary data
Journal Articles

Use of the Glucose Starvation-inducible Glucose-regulated Protein 78 Promoter in Suicide Gene Therapy of Murine Fibrosarcoma

Gadi Gazit, Gene Hung, Xinke Chen, W. French Anderson, Amy S. Lee
Journal: Cancer Research
Cancer Res (1999) 59 (13): 3100–3106.
Published: 01 July 1999
View article
Journal Articles

Amplification and Overexpression of HER-2/neu in Carcinomas of the Salivary Gland: Correlation with Poor Prognosis

Michael F. Press, Malcolm C. Pike, Gene Hung, Jian Yuan Zhou, Yanling Ma, Jay George, Jeanne Dietz-Band, William James, Dennis J. Slamon, John G. Batsakis, Adel K. El-Naggar
Journal: Cancer Research
Cancer Res (1994) 54 (21): 5675–5682.
Published: 01 November 1994
View article
PDF
Journal Articles

Sensitivity of HER-2/neu Antibodies in Archival Tissue Samples: Potential Source of Error in Immunohistochemical Studies of Oncogene Expression

Michael F. Press, Gene Hung, William Godolphin, Dennis J. Slamon
Journal: Cancer Research
Cancer Res (1994) 54 (10): 2771–2777.
Published: 01 May 1994
View article
PDF
Journal Articles

Her-2/neu Expression in Node-negative Breast Cancer: Direct Tissue Quantitation by Computerized Image Analysis and Association of Overexpression with Increased Risk of Recurrent Disease

Michael F. Press, Malcolm C. Pike, Victoria R. Chazin, Gene Hung, Judith A. Udove, Mitchell Markowicz, John Danyluk, William Godolphin, Mark Sliwkowski, Robert Akita, Malcolm C. Paterson, Dennis J. Slamon
Journal: Cancer Research
Cancer Res (1993) 53 (20): 4960–4970.
Published: 01 October 1993
View article
PDF