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Journal Articles

Abstract 5894: Novel splicing-derived neoantigen in triple negative breast cancer uncovered by SpliceIO™ a robust platform for the discovery and validation of disease-specific immunotherapies

Nicole Williams, Miguel A. Manzanares, Kendall Anderson, Hasan Zunrut, Sakshi Gera, Nayab Habib, Shaleigh Stanton, Taylor Floyd, Sanjana Shah, Devon Trahan, Martin Akerman, Gayatri Arun
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5894.
https://doi.org/10.1158/1538-7445.AM2024-5894
Published: 22 March 2024
View article titled, Abstract 5894: Novel splicing-derived neoantigen in triple negative breast cancer uncovered by SpliceIO™ a robust platform for the discovery and validation of disease-specific immunotherapies
Journal Articles

Abstract 5888: Novel immune-therapeutic target for lung cancer uncovered by SpliceIO™, an innovative platform that identifies disease-specific alternative splicing

Miguel A. Manzanares, Kendall Anderson, Hasan Zumrut, Sakshi Gera, Nayab Habib, Nicole Williams, Shaleigh Stanton, Taylor Floyd, Sanjana Shah, Devon Trahan, Martin Akerman, Gayatri Arun
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5888.
https://doi.org/10.1158/1538-7445.AM2024-5888
Published: 22 March 2024
View article titled, Abstract 5888: Novel immune-therapeutic target for lung cancer uncovered by SpliceIO™, an innovative platform that identifies disease-specific alternative splicing
Journal Articles

Abstract 448: Computational discovery and experimental validation of splicing-derived neoantigens

Hasan Ekrem Zumrut, Kendall Anderson, Miguel Manzanares, Shaleigh Smith, Sakshi Gera, Nayab Habib, Sanjana Shah, Devon Trahan, Martin Akerman, Gayatri Arun
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 448.
https://doi.org/10.1158/1538-7445.AM2023-448
Published: 04 April 2023
View article titled, Abstract 448: Computational discovery and experimental validation of splicing-derived neoantigens
Journal Articles

Abstract 1873: SpliceCore® a novel ML tool for identifying disease-specific alternative splicing uncovered a promising therapeutic target for triple negative breast cancer

Miguel A. Manzanares, Alyssa Casill, Kendall Anderson, Priyanka Dhingra, Vanessa Frederick, Adam Geier, Martin Akerman, Gayatri Arun
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1873.
https://doi.org/10.1158/1538-7445.AM2022-1873
Published: 15 June 2022
View article titled, Abstract 1873: SpliceCore® a novel ML tool for identifying disease-specific alternative splicing uncovered a promising therapeutic target for triple negative breast cancer
Journal Articles

Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic Characteristics

Sonam Bhatia, Melissa Kramer, Suzanne Russo, Payal Naik, Gayatri Arun, Kyle Brophy, Peter Andrews, Cheng Fan, Charles M. Perou, Jonathan Preall, Taehoon Ha, Dennis Plenker, David A. Tuveson, Arvind Rishi, John E. Wilkinson, W. Richard McCombie, Karen Kostroff, David L. Spector
Journal: Cancer Research
Cancer Res (2022) 82 (7): 1174–1192.
https://doi.org/10.1158/0008-5472.CAN-21-2807
Published: 01 April 2022
View article titled, Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic Characteristics
Open the PDF for Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic Characteristics in another window
Includes: Supplementary data
Journal Articles

Abstract P5-17-11: Novel therapeutic target for triple negative breast cancer uncovered by SpliceCore® an innovative platform that identifies disease-specific alternative splicing

Miguel A Manzanares, Priyanka Dhingra, Kendall Anderson, Vanessa Frederick, Adam Geier, Alyssa Casill, Martin Akerman, Gayatri Arun
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P5-17-11.
https://doi.org/10.1158/1538-7445.SABCS21-P5-17-11
Published: 15 February 2022
View article titled, Abstract P5-17-11: Novel therapeutic target for triple negative breast cancer uncovered by SpliceCore® an innovative platform that identifies disease-specific alternative splicing
Journal Articles

Abstract P3-11-21: Identification and characterization of novel splice variants in triple-negative breast cancer

Gayatri Arun, Priyanka Dhingra, Robin Munch, Vanessa Fredrick, Martin Akerman
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P3-11-21.
https://doi.org/10.1158/1538-7445.SABCS19-P3-11-21
Published: 15 February 2020
View article titled, Abstract P3-11-21: Identification and characterization of novel splice variants in triple-negative breast cancer
Journal Articles

Abstract PR11: Differentiation of mammary tumors and reduction in metastasis upon Malat1 LncRNA loss

Gayatri Arun, Sarah Diermeier, Martin Akerman, Kung-Chi Chang, J.Erby Wilkinson, Stephen Hearn, Youngsoo Kim, A.Robert MacLeod, Adrian R. Krainer, Larry Norton, Edi Brogi, Mikala Egeblad, David L. Spector
Journal: Cancer Research
Cancer Res (2016) 76 (6_Supplement): PR11.
https://doi.org/10.1158/1538-7445.NONRNA15-PR11
Published: 13 May 2016
View article titled, Abstract PR11: Differentiation of mammary tumors and reduction in metastasis upon Malat1 LncRNA loss
Journal Articles

Abstract 1121: The long non-coding RNA MALAT1 is an essential gene regulator for lung cancer metastasis in a novel human knockout model .

Tony Gutschner, Monika Hämmerle, Moritz Eißmann, Jeff Hsu, Youngsoo Kim, Gene Hung, Alexey Revenko, Gayatri Arun, Marion Stentrup, Matthias Groß, Martin Zörnig, A. Robert MacLeod, David L. Spector, Sven Diederichs
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1121.
https://doi.org/10.1158/1538-7445.AM2013-1121
Published: 15 April 2013
View article titled, Abstract 1121: The long non-coding RNA MALAT1 is an essential gene regulator for lung cancer metastasis in a novel human knockout model .
Journal Articles

The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells

Tony Gutschner, Monika Hämmerle, Moritz Eißmann, Jeff Hsu, Youngsoo Kim, Gene Hung, Alexey Revenko, Gayatri Arun, Marion Stentrup, Matthias Groß, Martin Zörnig, A. Robert MacLeod, David L. Spector, Sven Diederichs
Journal: Cancer Research
Cancer Res (2013) 73 (3): 1180–1189.
https://doi.org/10.1158/0008-5472.CAN-12-2850
Published: 31 January 2013
View article titled, The Noncoding RNA <em>MALAT1</em> Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells
Open the PDF for The Noncoding RNA <em>MALAT1</em> Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells in another window
Includes: Supplementary data