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Gary J. Kelloff
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Journal Articles

Challenges to Using Big Data in Cancer

Shawn M. Sweeney, Hisham K. Hamadeh, Natalie Abrams, Stacey J. Adam, Sara Brenner, Dana E. Connors, Gerard J. Davis, Louis Fiore, Susan H. Gawel, Robert L. Grossman, Sean E. Hanlon, Karl Hsu, Gary J. Kelloff, Ilan R. Kirsch, Bill Louv, Deven McGraw, Frank Meng, Daniel Milgram, Robert S. Miller, Emily Morgan, Lata Mukundan, Thomas O'Brien, Paul Robbins, Eric H. Rubin, Wendy S. Rubinstein, Liz Salmi, Teilo Schaller, George Shi, Caroline C. Sigman, Sudhir Srivastava
Journal: Cancer Research
Cancer Res (2023) 83 (8): 1175–1182.
https://doi.org/10.1158/0008-5472.CAN-22-1274
Published: 14 April 2023
View article titled, Challenges to Using Big Data in Cancer
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Journal Articles

Case Studies for Overcoming Challenges in Using Big Data in Cancer

Shawn M. Sweeney, Hisham K. Hamadeh, Natalie Abrams, Stacey J. Adam, Sara Brenner, Dana E. Connors, Gerard J. Davis, Louis D. Fiore, Susan H. Gawel, Robert L. Grossman, Sean E. Hanlon, Karl Hsu, Gary J. Kelloff, Ilan R. Kirsch, Bill Louv, Deven McGraw, Frank Meng, Daniel Milgram, Robert S. Miller, Emily Morgan, Lata Mukundan, Thomas O'Brien, Paul Robbins, Eric H. Rubin, Wendy S. Rubinstein, Liz Salmi, Teilo H. Schaller, George Shi, Caroline C. Sigman, Sudhir Srivastava
Journal: Cancer Research
Cancer Res (2023) 83 (8): 1183–1190.
https://doi.org/10.1158/0008-5472.CAN-22-1277
Published: 14 April 2023
View article titled, Case Studies for Overcoming Challenges in Using Big Data in Cancer
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Journal Articles

9- cis -Retinoic Acid but Not 4-(Hydroxyphenyl)retinamide Inhibits Prostate Intraepithelial Neoplasia in Noble Rats

Konstantin T. Christov, Richard C. Moon, Daniel D. Lantvit, Charles W. Boone, Vernon E. Steele, Ronald A. Lubet, Gary J. Kelloff, John M. Pezzuto
Journal: Cancer Research
Cancer Res (2002) 62 (18): 5178–5182.
Published: 15 September 2002
View article titled, 9- <em>cis</em> -Retinoic Acid but Not 4-(Hydroxyphenyl)retinamide Inhibits Prostate Intraepithelial Neoplasia in Noble Rats
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Journal Articles

Modulation of Biomarkers by Chemopreventive Agents in Smoke-exposed Rats

Alberto Izzotti, Roumen M. Balansky, Francesco D’Agostini, Carlo Bennicelli, Steven R. Myers, Clinton J. Grubbs, Ronald A. Lubet, Gary J. Kelloff, Silvio De Flora
Journal: Cancer Research
Cancer Res (2001) 61 (6): 2472–2479.
Published: 03 March 2001
View article titled, Modulation of Biomarkers by Chemopreventive Agents in Smoke-exposed Rats
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Journal Articles

Celecoxib Inhibits N-Butyl-N-(4-hydroxybutyl)-nitrosamine-induced Urinary Bladder Cancers in Male B6D2F1 Mice and Female Fischer-344 Rats

Clinton J. Grubbs, Ronald A. Lubet, Alane T. Koki, Kathleen M. Leahy, Jaime L. Masferrer, Vernon E. Steele, Gary J. Kelloff, D. L. Hill, Karen Seibert
Journal: Cancer Research
Cancer Res (2000) 60 (20): 5599–5602.
Published: 15 October 2000
View article titled, Celecoxib Inhibits N-Butyl-N-(4-hydroxybutyl)-nitrosamine-induced Urinary Bladder Cancers in Male B6D2F1 Mice and Female Fischer-344 Rats
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Journal Articles

A Germ-Line p53 Mutation Accelerates Pulmonary Tumorigenesis: p53-independent Efficacy of Chemopreventive Agents Green Tea or Dexamethasone/myo-Inositol and Chemotherapeutic Agents Taxol or Adriamycin

Zhongqiu Zhang, Qing Liu, Laura E. Lantry, Yian Wang, Gary J. Kelloff, Marshall W. Anderson, Roger W. Wiseman, Ronald A. Lubet, Ming You
Journal: Cancer Research
Cancer Res (2000) 60 (4): 901–907.
Published: 01 February 2000
View article titled, A Germ-Line <em>p53</em> Mutation Accelerates Pulmonary Tumorigenesis: p53-independent Efficacy of Chemopreventive Agents Green Tea or Dexamethasone/<em>myo</em>-Inositol and Chemotherapeutic Agents Taxol or Adriamycin
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Journal Articles

Patterns of DNA Adduct Formation in Liver and Mammary Epithelial Cells of Rats Treated with 7,12-Dimethylbenz(a)anthracene, and Selective Effects of Chemopreventive Agents

Alberto Izzotti, Anna Camoirano, Cristina Cartiglia, Clinton J. Grubbs, Ronald A. Lubet, Gary J. Kelloff, Silvio De Flora
Journal: Cancer Research
Cancer Res (1999) 59 (17): 4285–4290.
Published: 01 September 1999
View article titled, Patterns of DNA Adduct Formation in Liver and Mammary Epithelial Cells of Rats Treated with 7,12-Dimethylbenz(<em>a</em>)anthracene, and Selective Effects of Chemopreventive Agents
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Journal Articles

Chemopreventive Efficacy of Sulindac Sulfone against Colon Cancer Depends on Time of Administration during Carcinogenic Process

Bandaru S. Reddy, Toshihiko Kawamori, Ronald A. Lubet, Vernon E. Steele, Gary J. Kelloff, Chinthalapally V. Rao
Journal: Cancer Research
Cancer Res (1999) 59 (14): 3387–3391.
Published: 15 July 1999
View article titled, Chemopreventive Efficacy of Sulindac Sulfone against Colon Cancer Depends on Time of Administration during Carcinogenic Process
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Journal Articles

Chemoprevention of Rat Prostate Carcinogenesis by Early and Delayed Administration of Dehydroepiandrosterone

K. V. N. Rao, William D. Johnson, Maarten C. Bosland, Ronald A. Lubet, Vernon E. Steele, Gary J. Kelloff, David L. McCormick
Journal: Cancer Research
Cancer Res (1999) 59 (13): 3084–3089.
Published: 01 July 1999
View article titled, Chemoprevention of Rat Prostate Carcinogenesis by Early and Delayed Administration of Dehydroepiandrosterone
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Journal Articles

Chemoprevention of Rat Prostate Carcinogenesis by 9-cis-Retinoic Acid

David L. McCormick, K. V. N. Rao, Vernon E. Steele, Ronald A. Lubet, Gary J. Kelloff, Maarten C. Bosland
Journal: Cancer Research
Cancer Res (1999) 59 (3): 521–524.
Published: 01 February 1999
View article titled, Chemoprevention of Rat Prostate Carcinogenesis by 9-<em>cis</em>-Retinoic Acid
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Journal Articles

Chemopreventive Effect of Curcumin, a Naturally Occurring Anti-Inflammatory Agent, during the Promotion/Progression Stages of Colon Cancer

Toshihiko Kawamori, Ronald Lubet, Vernon E. Steele, Gary J. Kelloff, Robert B. Kaskey, Chinthalapally V. Rao, Bandaru S. Reddy
Journal: Cancer Research
Cancer Res (1999) 59 (3): 597–601.
Published: 01 February 1999
View article titled, Chemopreventive Effect of Curcumin, a Naturally Occurring Anti-Inflammatory Agent, during the Promotion/Progression Stages of Colon Cancer
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Journal Articles

Influence of N-Methyl-N-Nitrosourea, Testosterone, and N-(4-Hydroxyphenyl)-all-trans-retinamide on Prostate Cancer Induction in Wistar-Unilever Rats

David L. McCormick, K. V. N. Rao, Lawrence Dooley, Vernon E. Steele, Ronald A. Lubet, Gary J. Kelloff, Maarten C. Bosland
Journal: Cancer Research
Cancer Res (1998) 58 (15): 3282–3288.
Published: 01 August 1998
View article titled, Influence of <em>N</em>-Methyl-<em>N</em>-Nitrosourea, Testosterone, and <em>N</em>-(4-Hydroxyphenyl)-all-<em>trans</em>-retinamide on Prostate Cancer Induction in Wistar-Unilever Rats
Open the PDF for Influence of <em>N</em>-Methyl-<em>N</em>-Nitrosourea, Testosterone, and <em>N</em>-(4-Hydroxyphenyl)-all-<em>trans</em>-retinamide on Prostate Cancer Induction in Wistar-Unilever Rats in another window
Journal Articles

Modulation of Methylnitrosourea-induced Breast Cancer in Sprague Dawley Rats by Dehydroepiandrosterone: Dose-dependent Inhibition, Effects of Limited Exposure, Effects on Peroxisomal Enzymes, and Lack of Effects on Levels of Ha-Ras Mutations

Ronald A. Lubet, Gary B. Gordon, Russell A. Prough, Xiang-Dong Lei, Ming You, Yian Wang, Clinton J. Grubbs, Vernon E. Steele, Gary J. Kelloff, Cathy F. Thomas, Richard D. Moon
Journal: Cancer Research
Cancer Res (1998) 58 (5): 921–926.
Published: 01 March 1998
View article titled, Modulation of Methylnitrosourea-induced Breast Cancer in Sprague Dawley Rats by Dehydroepiandrosterone: Dose-dependent Inhibition, Effects of Limited Exposure, Effects on Peroxisomal Enzymes, and Lack of Effects on Levels of Ha-<em>Ras</em> Mutations
Open the PDF for Modulation of Methylnitrosourea-induced Breast Cancer in Sprague Dawley Rats by Dehydroepiandrosterone: Dose-dependent Inhibition, Effects of Limited Exposure, Effects on Peroxisomal Enzymes, and Lack of Effects on Levels of Ha-<em>Ras</em> Mutations in another window
Journal Articles

Chemoprevention of Pulmonary Carcinogenesis by Aerosolized Budesonide in Female A/J Mice

Lee W. Wattenberg, Timothy S. Wiedmann, Richard D. Estensen, Cheryl L. Zimmerman, Vernon E. Steele, Gary J. Kelloff
Journal: Cancer Research
Cancer Res (1997) 57 (24): 5489–5492.
Published: 01 December 1997
View article titled, Chemoprevention of Pulmonary Carcinogenesis by Aerosolized Budesonide in Female A/J Mice
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Journal Articles

Modulation of Apoptosis by Sulindac, Curcumin, Phenylethyl-3-methylcaffeate, and 6-Phenylhexyl Isothiocyanate: Apoptotic Index as a Biomarker in Colon Cancer Chemoprevention and Promotion

Hanan S. Samaha, Gary J. Kelloff, Vernon Steele, Chinthalapally V. Rao, Bandaru S. Reddy
Journal: Cancer Research
Cancer Res (1997) 57 (7): 1301–1305.
Published: 01 April 1997
View article titled, Modulation of Apoptosis by Sulindac, Curcumin, Phenylethyl-3-methylcaffeate, and 6-Phenylhexyl Isothiocyanate: Apoptotic Index as a Biomarker in Colon Cancer Chemoprevention and Promotion
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Journal Articles

Chemoprevention of Colon Carcinogenesis by Dietary Perillyl Alcohol

Bandaru S. Reddy, C-X. Wang, Hanan Samaha, Ronald Lubet, Vernon E. Steele, Gary J. Kelloff, Chinthalapally V. Rao
Journal: Cancer Research
Cancer Res (1997) 57 (3): 420–425.
Published: 01 February 1997
View article titled, Chemoprevention of Colon Carcinogenesis by Dietary Perillyl Alcohol
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Journal Articles

Prostate Cancer Prevention: Investigational Approaches and Opportunities

Judith E. Karp, Andrew Chiarodo, Otis Brawley, Gary J. Kelloff
Journal: Cancer Research
Cancer Res (1996) 56 (24): 5547–5556.
Published: 01 December 1996
View article titled, Prostate Cancer Prevention: Investigational Approaches and Opportunities
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Journal Articles

Apoptosis, Cell Replication, and Western-style Diet-induced Tumorigenesis in Mouse Colon

Mauro Risio, Martin Lipkin, Harold Newmark, Kan Yang, Francesco P. Rossini, Vernon E. Steele, Charles W. Boone, Gary J. Kelloff
Journal: Cancer Research
Cancer Res (1996) 56 (21): 4910–4916.
Published: 01 November 1996
View article titled, Apoptosis, Cell Replication, and Western-style Diet-induced Tumorigenesis in Mouse Colon
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Journal Articles

Cytokeratin, Lectin, and Acidic Mucin Modulation in Differentiating Colonic Epithelial Cells of Mice after Feeding Western-style Diets

Kan Yang, Kunhua Fan, Harold Newmark, Denis Leung, Martin Lipkin, Vernon E. Steele, Gary J. Kelloff
Journal: Cancer Research
Cancer Res (1996) 56 (20): 4644–4648.
Published: 01 October 1996
View article titled, Cytokeratin, Lectin, and Acidic Mucin Modulation in Differentiating Colonic Epithelial Cells of Mice after Feeding Western-style Diets
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Journal Articles

Exceptional Chemopreventive Activity of Low-Dose Dehydroepiandrosterone in the Rat Mammary Gland

David L. McCormick, Kandala V. N. Rao, William D. Johnson, Teresa A. Bowman-Gram, Vernon E. Steele, Ronald A. Lubet, Gary J. Kelloff
Journal: Cancer Research
Cancer Res (1996) 56 (8): 1724–1726.
Published: 01 April 1996
View article titled, Exceptional Chemopreventive Activity of Low-Dose Dehydroepiandrosterone in the Rat Mammary Gland
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