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Garry R. Buettner
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Journal Articles

Abstract 4677: Characterizing resistant and metastatic phenotypes to pharmacological ascorbate in pancreatic cancer

Amanda N. Pope, Brianne R. O'Leary, Juan Du, Garry R. Buettner, Michael D. Henry, Joseph J. Cullen
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4677.
https://doi.org/10.1158/1538-7445.AM2024-4677
Published: 22 March 2024
View articletitled, Abstract 4677: Characterizing resistant and metastatic phenotypes to pharmacological ascorbate in pancreatic cancer
Journal Articles

Abstract CT164: Pharmacological ascorbate enhances platinum-based chemotherapy responses in metastatic non-small cell lung cancer (NSCLC): A phase II clinical trial

Muhammad Furqan, Taher Abu-Hejleh, Kellie L. Bodeker, Laura M. Pietrok, Stacey M. Hartwig, Mikaela M. Tremblay, Micaela G. Fosdick, Jon Houtman, Steven Varga, Casey F. Pulliam, Michael Petronek, Melissa A. Fath, Sarah L. Mott, Aaron D. Bossler, Andrew M. Bellizzi, Jun Zhang, Hariharasudan Mani, Varun Monga, Brian J. Smith, Joseph Cullen, Brett A. Wagner, Garry R. Buettner, John M. Buatti, Douglas R. Spitz, Bryan G. Allen
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): CT164.
https://doi.org/10.1158/1538-7445.AM2021-CT164
Published: 01 July 2021
View articletitled, Abstract CT164: Pharmacological ascorbate enhances platinum-based chemotherapy responses in metastatic non-small cell lung cancer (NSCLC): A phase II clinical trial
Journal Articles

Dual Oxidase-Induced Sustained Generation of Hydrogen Peroxide Contributes to Pharmacologic Ascorbate-Induced Cytotoxicity

Adrienne R. Gibson, Brianne R. O'Leary, Juan Du, Ehab H. Sarsour, Amanda L. Kalen, Brett A. Wagner, Jeffrey M. Stolwijk, Kelly C. Falls-Hubert, Matthew S. Alexander, Rory S. Carroll, Douglas R. Spitz, Garry R. Buettner, Prabhat C. Goswami, Joseph J. Cullen
Journal: Cancer Research
Cancer Res (2020) 80 (7): 1401–1413.
https://doi.org/10.1158/0008-5472.CAN-19-3094
Published: 02 April 2020
View articletitled, Dual Oxidase-Induced Sustained Generation of Hydrogen Peroxide Contributes to Pharmacologic Ascorbate-Induced Cytotoxicity
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Includes: Supplementary data
Journal Articles

Pharmacologic Ascorbate Reduces Radiation-Induced Normal Tissue Toxicity and Enhances Tumor Radiosensitization in Pancreatic Cancer

Matthew S. Alexander, Justin G. Wilkes, Samuel R. Schroeder, Garry R. Buettner, Brett A. Wagner, Juan Du, Katherine Gibson-Corley, Brianne R. O’Leary, Douglas R. Spitz, John M. Buatti, Daniel J. Berg, Kellie L. Bodeker, Sandy Vollstedt, Heather A. Brown, Bryan G. Allen, Joseph J. Cullen
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (24): 6838–6851.
https://doi.org/10.1158/0008-5472.CAN-18-1680
Published: 13 December 2018
View articletitled, Pharmacologic Ascorbate Reduces Radiation-Induced Normal Tissue Toxicity and Enhances Tumor Radiosensitization in Pancreatic Cancer
Open the PDF for Pharmacologic Ascorbate Reduces Radiation-Induced Normal Tissue Toxicity and Enhances Tumor Radiosensitization in Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Pharmacological Ascorbate Radiosensitizes Pancreatic Cancer

Juan Du, John A. Cieslak, III, Jessemae L. Welsh, Zita A. Sibenaller, Bryan G. Allen, Brett A. Wagner, Amanda L. Kalen, Claire M. Doskey, Robert K. Strother, Anna M. Button, Sarah L. Mott, Brian Smith, Susan Tsai, James Mezhir, Prabhat C. Goswami, Douglas R. Spitz, Garry R. Buettner, Joseph J. Cullen
Journal: Cancer Research
Series: Author Choice
Cancer Res (2015) 75 (16): 3314–3326.
https://doi.org/10.1158/0008-5472.CAN-14-1707
Published: 13 August 2015
View articletitled, Pharmacological Ascorbate Radiosensitizes Pancreatic Cancer
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Includes: Supplementary data
Journal Articles

Manganoporphyrins Increase Ascorbate-Induced Cytotoxicity by Enhancing H2O2 Generation

Malvika Rawal, Samuel R. Schroeder, Brett A. Wagner, Cameron M. Cushing, Jessemae L. Welsh, Anna M. Button, Juan Du, Zita A. Sibenaller, Garry R. Buettner, Joseph J. Cullen
Journal: Cancer Research
Series: Author Choice
Cancer Res (2013) 73 (16): 5232–5241.
https://doi.org/10.1158/0008-5472.CAN-13-0470
Published: 13 August 2013
View articletitled, Manganoporphyrins Increase Ascorbate-Induced Cytotoxicity by Enhancing H2O2 Generation
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Includes: Supplementary data
Journal Articles

Manganese Superoxide Dismutase Regulates a Metabolic Switch during the Mammalian Cell Cycle

Ehab H. Sarsour, Amanda L. Kalen, Zhen Xiao, Timothy D. Veenstra, Leena Chaudhuri, Sujatha Venkataraman, Philip Reigan, Garry R. Buettner, Prabhat C. Goswami
Journal: Cancer Research
Cancer Res (2012) 72 (15): 3807–3816.
https://doi.org/10.1158/0008-5472.CAN-11-1063
Published: 31 July 2012
View articletitled, Manganese Superoxide Dismutase Regulates a Metabolic Switch during the Mammalian Cell Cycle
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Includes: Supplementary data
Journal Articles

Manganese Superoxide Dismutase Modulates Hypoxia-Inducible Factor-1α Induction via Superoxide

Suwimol Kaewpila, Sujatha Venkataraman, Garry R. Buettner, Larry W. Oberley
Journal: Cancer Research
Cancer Res (2008) 68 (8): 2781–2788.
https://doi.org/10.1158/0008-5472.CAN-07-2635
Published: 15 April 2008
View articletitled, Manganese Superoxide Dismutase Modulates Hypoxia-Inducible Factor-1α Induction via Superoxide
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Journal Articles

Sensitivity of K562 and HL-60 Cells to Edelfosine, an Ether Lipid Drug, Correlates with Production of Reactive Oxygen Species

Brett A. Wagner, Garry R. Buettner, Larry W. Oberley, C. Patrick Burns
Journal: Cancer Research
Cancer Res (1998) 58 (13): 2809–2816.
Published: 01 July 1998
View articletitled, Sensitivity of K562 and HL-60 Cells to Edelfosine, an Ether Lipid Drug, Correlates with Production of Reactive Oxygen Species
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Journal Articles

Membrane Lipid Free Radicals Produced from L1210 Murine Leukemia Cells by Photofrin Photosensitization: An Electron Paramagnetic Resonance Spin Trapping Study

Garry R. Buettner, Eric E. Kelley, C. Patrick Burns
Journal: Cancer Research
Cancer Res (1993) 53 (16): 3670–3673.
Published: 01 August 1993
View articletitled, Membrane Lipid Free Radicals Produced from L1210 Murine Leukemia Cells by Photofrin Photosensitization: An Electron Paramagnetic Resonance Spin Trapping Study
Open the PDF for Membrane Lipid Free Radicals Produced from L1210 Murine Leukemia Cells by Photofrin Photosensitization: An Electron Paramagnetic Resonance Spin Trapping Study in another window
Journal Articles

Increased Generation of Lipid-derived and Ascorbate Free Radicals by L1210 Cells Exposed to the Ether Lipid Edelfosine

Brett A. Wagner, Garry R. Buettner, C. Patrick Burns
Journal: Cancer Research
Cancer Res (1993) 53 (4): 711–713.
Published: 01 February 1993
View articletitled, Increased Generation of Lipid-derived and Ascorbate Free Radicals by L1210 Cells Exposed to the Ether Lipid Edelfosine
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Journal Articles

Membrane Peroxidative Damage Enhancement by the Ether Lipid Class of Antineoplastic Agents

Brett A. Wagner, Garry R. Buettner, C. Patrick Burns
Journal: Cancer Research
Cancer Res (1992) 52 (21): 6045–6051.
Published: 01 November 1992
View articletitled, Membrane Peroxidative Damage Enhancement by the Ether Lipid Class of Antineoplastic Agents
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Journal Articles

Effect of Modification of Plasma Membrane Fatty Acid Composition on Fluidity and Methotrexate Transport in L1210 Murine Leukemia Cells

C. Patrick Burns, Diana G. Luttenegger, David T. Dudley, Garry R. Buettner, Arthur A. Spector
Journal: Cancer Research
Cancer Res (1979) 39 (5): 1726–1732.
Published: 01 May 1979
View articletitled, Effect of Modification of Plasma Membrane Fatty Acid Composition on Fluidity and Methotrexate Transport in L1210 Murine Leukemia Cells
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Journal Articles

Role of Superoxide Dismutase in Cancer: A Review

Larry W. Oberley, Garry R. Buettner
Journal: Cancer Research
Cancer Res (1979) 39 (4): 1141–1149.
Published: 01 April 1979
View articletitled, Role of Superoxide Dismutase in Cancer: A Review
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