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Garrett M. Brodeur
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Journal Articles

Abstract A023 Establishment of the consortium for childhood cancer predisposition and the childhood cancer predisposition study

Christopher C. Porter, Garrett M. Brodeur, Lisa Diller, Chloe Edgerton, Junne Kamihara, Wendy Kohlmann, Suzanne P. MacFarland, Luke Maese, David Malkin, Kim E. Nichols, Melissa R. Perrino, Sharon E. Plon, Surya Rednam, Anita Villani
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement): A023.
https://doi.org/10.1158/1538-7445.PEDIATRIC24-A023
Published: 05 September 2024
View articletitled, Abstract A023 Establishment of the consortium for childhood cancer predisposition and the childhood cancer predisposition study
Journal Articles

Abstract 6376: Establishment of the Consortium for Childhood Cancer Predisposition and the Childhood Cancer Predisposition Study

Anita Villani, Garrett M. Brodeur, Lisa R. Diller, Chloe Edgerton, Junne Kamihara, Wendy Kohlmann, Suzanne P. MacFarland, Luke Maese, David Malkin, Kim E. Nichols, Melissa R. Perrino, Sharon E. Plon, Surya Rednam, Christopher C. Porter
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6376.
https://doi.org/10.1158/1538-7445.AM2024-6376
Published: 22 March 2024
View articletitled, Abstract 6376: Establishment of the Consortium for Childhood Cancer Predisposition and the Childhood Cancer Predisposition Study
Journal Articles

Abstract 5220: The consequences of 11p15 mosaicism in Beckwith-Wiedemann syndrome/spectrum: Epigenotypes associated with cancer development and necessity for universal tumor screening

Kelly A. Duffy, Evan R. Hathaway, Mallory E. Byrne, Andrew M. George, Timothy Mcelroy, Suzanne P. MacFarland, Garrett M. Brodeur, Jennifer M. Kalish
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5220.
https://doi.org/10.1158/1538-7445.AM2022-5220
Published: 15 June 2022
View articletitled, Abstract 5220: The consequences of 11p15 mosaicism in Beckwith-Wiedemann syndrome/spectrum: Epigenotypes associated with cancer development and necessity for universal tumor screening
Journal Articles

Abstract 5898: Bone morphogenic protein receptor 2 (BMPR2) as a potential germline driver in Juvenile Polyposis Syndrome (JPS)

Suzanne P. MacFarland, Bridgid Greed, Michael H. Xie, Garrett M. Brodeur, Zvi Cramer, Maiah H. Dent, Melani M. Duvall, Kathryn E. Hamilton, James Howe, Tatiana Karakasheva, Petar Mamula, Christopher Lengner
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5898.
https://doi.org/10.1158/1538-7445.AM2022-5898
Published: 15 June 2022
View articletitled, Abstract 5898: Bone morphogenic protein receptor 2 (BMPR2) as a potential germline driver in Juvenile Polyposis Syndrome (JPS)
Journal Articles

Structural Optimization and Enhanced Prodrug-Mediated Delivery Overcomes Camptothecin Resistance in High-Risk Solid Tumors

Ferro Nguyen, Peng Guan, David T. Guerrero, Venkatadri Kolla, Koumudi Naraparaju, Lauren M. Perry, Danielle Soberman, Benjamin B. Pressly, Ivan S. Alferiev, Michael Chorny, Garrett M. Brodeur
Journal: Cancer Research
Cancer Res (2020) 80 (19): 4258–4265.
https://doi.org/10.1158/0008-5472.CAN-20-1344
Published: 02 October 2020
View articletitled, Structural Optimization and Enhanced Prodrug-Mediated Delivery Overcomes Camptothecin Resistance in High-Risk Solid Tumors
Open the PDF for Structural Optimization and Enhanced Prodrug-Mediated Delivery Overcomes Camptothecin Resistance in High-Risk Solid Tumors in another window
Includes: Supplementary data
Journal Articles

Abstract CT030: STARTRK-NG: A phase 1/1b study of entrectinib in children and adolescents with advanced solid tumors and primary CNS tumors, with or without TRK, ROS1, or ALK fusions

Ami V. Desai, Garrett M. Brodeur, Jennifer Foster, Suzanne Shusterman, Amit J. Sabnis, Magaret Macy, Cynthia Wetmore, Ellen Basu, Zachary Hornby, Vanessa Esquibel, Edna Chow Maneval, Pratik S. Multani, Elizabeth Fox
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): CT030.
https://doi.org/10.1158/1538-7445.AM2017-CT030
Published: 01 July 2017
View articletitled, Abstract CT030: STARTRK-NG: A phase 1/1b study of entrectinib in children and adolescents with advanced solid tumors and primary CNS tumors, with or without TRK, ROS1, or ALK fusions
Journal Articles

Abstract 191: The role of microRNAs in the epigenetic silencing of CHD5, a tumor suppressor in neuroblastoma

Koumudi Naraparaju, Venkatadri Kolla, Tiangang Zhuang, Mayumi Higashi, Gerd A. Blobel, Garrett M. Brodeur
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 191.
https://doi.org/10.1158/1538-7445.AM2015-191
Published: 01 August 2015
View articletitled, Abstract 191: The role of microRNAs in the epigenetic silencing of CHD5, a tumor suppressor in neuroblastoma
Journal Articles

Abstract 5390: The TRK inhibitor RXDX-101 enhances the efficacy of temozolomide and irinotecan in a xenograft model of neuroblastoma

Radhika Iyer, Rebecca L. Golden, Koumudi Naraparaju, Jamie L. Croucher, Peng Guan, Gang Li, Zachary Hornby, Garrett M. Brodeur
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5390.
https://doi.org/10.1158/1538-7445.AM2015-5390
Published: 01 August 2015
View articletitled, Abstract 5390: The TRK inhibitor RXDX-101 enhances the efficacy of temozolomide and irinotecan in a xenograft model of neuroblastoma
Journal Articles

Abstract 5537: Nanoparticle delivery of an SN38 conjugate is more effective than Irinotecan in a mouse model of Neuroblastoma

Radhika Iyer, Jamie L. Croucher, Michael Chorny, Jennifer L. Mangino, Ivan S. Alferiev, Robert J. Levy, Venkatadri Kolla, Garrett M. Brodeur
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5537.
https://doi.org/10.1158/1538-7445.AM2015-5537
Published: 01 August 2015
View articletitled, Abstract 5537: Nanoparticle delivery of an SN38 conjugate is more effective than Irinotecan in a mouse model of Neuroblastoma
Journal Articles

Role of CHD5 in Human Cancers: 10 Years Later

Venkatadri Kolla, Tiangang Zhuang, Mayumi Higashi, Koumudi Naraparaju, Garrett M. Brodeur
Journal: Cancer Research
Cancer Res (2014) 74 (3): 652–658.
https://doi.org/10.1158/0008-5472.CAN-13-3056
Published: 02 February 2014
View articletitled, Role of CHD5 in Human Cancers: 10 Years Later
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Journal Articles

Abstract 5257: Preclinical evaluation of lestaurtinib (CEP-701) with the retinoids for neuroblastoma

Robin E. Norris, Jane E. Minturn, Garrett M. Brodeur, John M. Maris, Peter C. Adamson
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5257.
https://doi.org/10.1158/1538-7445.AM10-5257
Published: 15 April 2010
View articletitled, Abstract 5257: Preclinical evaluation of lestaurtinib (CEP-701) with the retinoids for neuroblastoma
Journal Articles

Integrative Genomics Identifies Distinct Molecular Classes of Neuroblastoma and Shows That Multiple Genes Are Targeted by Regional Alterations in DNA Copy Number

Qun Wang, Sharon Diskin, Eric Rappaport, Edward Attiyeh, Yael Mosse, Daniel Shue, Eric Seiser, Jayanti Jagannathan, Suzanne Shusterman, Manisha Bansal, Deepa Khazi, Cynthia Winter, Erin Okawa, Gregory Grant, Avital Cnaan, Huaqing Zhao, Nai-Kong Cheung, William Gerald, Wendy London, Katherine K. Matthay, Garrett M. Brodeur, John M. Maris
Journal: Cancer Research
Cancer Res (2006) 66 (12): 6050–6062.
https://doi.org/10.1158/0008-5472.CAN-05-4618
Published: 15 June 2006
View articletitled, Integrative Genomics Identifies Distinct Molecular Classes of Neuroblastoma and Shows That Multiple Genes Are Targeted by Regional Alterations in DNA Copy Number
Open the PDF for Integrative Genomics Identifies Distinct Molecular Classes of Neuroblastoma and Shows That Multiple Genes Are Targeted by Regional Alterations in DNA Copy Number in another window
Includes: Supplementary data
Journal Articles

Proliferation of Human Neuroblastomas Mediated by the Epidermal Growth Factor Receptor

Ruth Ho, Jane E. Minturn, Tomoro Hishiki, Huaqing Zhao, Qun Wang, Avital Cnaan, John Maris, Audrey E. Evans, Garrett M. Brodeur
Journal: Cancer Research
Cancer Res (2005) 65 (21): 9868–9875.
https://doi.org/10.1158/0008-5472.CAN-04-2426
Published: 01 November 2005
View articletitled, Proliferation of Human Neuroblastomas Mediated by the Epidermal Growth Factor Receptor
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Journal Articles

Germline PHOX2B mutations in neuroblastoma suggest an oligogenic mechanism of tumorigenesis

Yael P. Mosse, Marci Laudenslager, Deepa Khazi, George Hii, Alex Carlisle, Eric Raabe, Huaqing Zhao, Eric Rappaport, Garrett M. Brodeur, John M. Maris
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1023–1024.
Published: 01 May 2005
View articletitled, Germline PHOX2B mutations in neuroblastoma suggest an oligogenic mechanism of tumorigenesis
Journal Articles

Combining genome-wide transcriptome and regional DNA copy number analyses for candidate gene discovery in neuroblastoma

Qun Wang, Sharon Diskin, Daniel Shue, Edward Attiyeh, Yael Mosse, Suzanne Shusterman, Rebecca King, Eric Rappaport, Deepa Khazi, Cynthia Winter, George Hii, Nicholas A. Rhodin, Jayanti Jagannathan, Gregory Grant, Mayadah Shabbout, Avital Cnnan, Garrett M. Brodeur, Nai-Kong Cheung, William Gerald, John Maris
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 689.
Published: 01 May 2005
View articletitled, Combining genome-wide transcriptome and regional DNA copy number analyses for candidate gene discovery in neuroblastoma
Journal Articles

Resistance to Chemotherapy Mediated by TrkB in Neuroblastomas

Ruth Ho, Angelika Eggert, Tomoro Hishiki, Jane E. Minturn, Naohiko Ikegaki, Patricia Foster, Anna Marie Camoratto, Audrey E. Evans, Garrett M. Brodeur
Journal: Cancer Research
Cancer Res (2002) 62 (22): 6462–6466.
Published: 15 November 2002
View articletitled, Resistance to Chemotherapy Mediated by TrkB in Neuroblastomas
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Journal Articles

Evidence for a Hereditary Neuroblastoma Predisposition Locus at Chromosome 16p12–13

John M. Maris, Matthew J. Weiss, Yael Mosse, George Hii, Chun Guo, Peter S. White, Michael D. Hogarty, Tamar Mirensky, Garrett M. Brodeur, Timothy R. Rebbeck, Margrit Urbanek, Suzanne Shusterman
Journal: Cancer Research
Cancer Res (2002) 62 (22): 6651–6658.
Published: 15 November 2002
View articletitled, Evidence for a Hereditary Neuroblastoma Predisposition Locus at Chromosome 16p12–13
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Journal Articles

No Evidence for the Presence of an Imprinted Neuroblastoma Suppressor Gene within Chromosome Sub-Band 1p36.3

Michael D. Hogarty, Cynthia L. Winter, Xueyuan Liu, Chun Guo, Peter S. White, A. Thomas Look, Garrett M. Brodeur, John M. Maris
Journal: Cancer Research
Cancer Res (2002) 62 (22): 6481–6484.
Published: 15 November 2002
View articletitled, No Evidence for the Presence of an Imprinted Neuroblastoma Suppressor Gene within Chromosome Sub-Band 1p36.3
Open the PDF for No Evidence for the Presence of an Imprinted Neuroblastoma Suppressor Gene within Chromosome Sub-Band 1p36.3 in another window
Journal Articles

Expression of the Neurotrophin Receptor TrkA Down-Regulates Expression and Function of Angiogenic Stimulators in SH-SY5Y Neuroblastoma Cells

Angelika Eggert, Michael A. Grotzer, Naohiko Ikegaki, Xing-ge Liu, Audrey E. Evans, Garrett M. Brodeur
Journal: Cancer Research
Cancer Res (2002) 62 (6): 1802–1808.
Published: 15 March 2002
View articletitled, Expression of the Neurotrophin Receptor TrkA Down-Regulates Expression and Function of Angiogenic Stimulators in SH-SY5Y Neuroblastoma Cells
Open the PDF for Expression of the Neurotrophin Receptor TrkA Down-Regulates Expression and Function of Angiogenic Stimulators in SH-SY5Y Neuroblastoma Cells in another window
Journal Articles

Resistance to Tumor Necrosis Factor-related Apoptosis-inducing Ligand-induced Apoptosis in Neuroblastoma Cells Correlates with a Loss of Caspase-8 Expression

Angelika Eggert, Michael A. Grotzer, Tycho J. Zuzak, Barbara R. Wiewrodt, Ruth Ho, Naohiko Ikegaki, Garrett M. Brodeur
Journal: Cancer Research
Cancer Res (2001) 61 (4): 1314–1319.
Published: 02 February 2001
View articletitled, Resistance to Tumor Necrosis Factor-related Apoptosis-inducing Ligand-induced Apoptosis in Neuroblastoma Cells Correlates with a Loss of Caspase-8 Expression
Open the PDF for Resistance to Tumor Necrosis Factor-related Apoptosis-inducing Ligand-induced Apoptosis in Neuroblastoma Cells Correlates with a Loss of Caspase-8 Expression in another window