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Journal Articles

Abstract 3940: Novel Bax activators for targeted breast cancer therapy

Doerte Raphaela Fricke, Gang Liu, Hyejin Kim, Pingyuan Wang, Xi Liu, Haiying Chen, Ruixia Ma, Junhai Xu, Jia Zhou, Qiang Shen
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3940.
DOI: https://doi.org/10.1158/1538-7445.AM2022-3940
Published: 15 June 2022
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Abstract 2201: Epithelial, stromal, and immune changes associated with lung squamous premalignant lesion severity identified by single-cell RNA-seq

Conor Shea, Lukas Kalinke, Kitty De Jong, Kate Gowers, Diane Ding, Sherry Zhang, Gang Liu, Jack Cunningham, Ipsita Dey-Guha, Mark Hennon, Sai Yendamuri, Christopher Stevenson, Avrum Spira, Mary E. Reid, Marc E. Lenburg, Sam M. Janes, Jennifer E. Beane, Sarah A. Mazzilli, Joshua D. Campbell
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2201.
DOI: https://doi.org/10.1158/1538-7445.AM2022-2201
Published: 15 June 2022
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Abstract 1488: The role of epithelial miR-149 in immune modulation and progression of bronchial premalignant lesions

Boting Ning, Roxana M. Pfefferkorn, Gang Liu, Sherry Zhang, Hanqiao Liu, Christopher Stevenson, Sarah A. Mazzilli, Avrum E. Spira, Marc E. Lenburg, Jennifer E. Beane
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1488.
DOI: https://doi.org/10.1158/1538-7445.AM2022-1488
Published: 15 June 2022
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Journal Articles

Abstract 5772: Differences in clinical actionability by comparing mutational landscape of young and old breast cancer patients

Jiaqi Liu, Ziqi Jia, Gang Liu, Xiang Wang, Qi Meng, Sha Wang, Yang Shao
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5772.
DOI: https://doi.org/10.1158/1538-7445.AM2022-5772
Published: 15 June 2022
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Journal Articles

Abstract 1239: Putative Bax activators GL0385 and GL0388 for targeted breast cancer therapy

Doerte R. Fricke, Hyejin Kim, Gang Liu, Haiying Chen, Jia Zhou, Qiang Shen
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1239.
DOI: https://doi.org/10.1158/1538-7445.AM2021-1239
Published: 01 July 2021
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Journal Articles

Abstract 2212: Cellular and molecular changes associated with lung squamous premalignant lesion severity identified by single-cell RNA-seq

Conor Shea, Lukas Kalinke, Kitty De Jong, Kate Gowers, Diane Ding, Sherry Zhang, Gang Liu, Jack Cunningham, Ipsita Dey-Guha, Mark Hennon, Sai Yendumuri, Christopher Stevenson, Steven Dubinett, Avrum Spira, Marc Lenburg, Samuel Janes, Mary Reid, Jennifer Beane, Sarah Mazzilli, Joshua D. Campbell
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2212.
DOI: https://doi.org/10.1158/1538-7445.AM2021-2212
Published: 01 July 2021
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Abstract 856: Proteomic analysis of serum in workers exposed to diesel engine exhaust

Mohammad L. Rahman, Yufei Dai, Roel Vermeulen, Wei Hu, Bryan Bassig, Eduard Drizik, Sean Corbett, Dianzhi Ren, Huawei Duan, Yong Niu, Jun Xu, Wei Fu, Kees Meliefste, Baosen Zhou, Xiaohui Zhang, Jufang Yang, Hanqiao Liu, Meng Ye, Gang Liu, Xiaowei Jia, Tao Meng, Ping Bin, Avrum Spira, Marc E. Lenburg, Debra Silverman, Nathaniel Rothman, Yuxin Zheng, Qing Lan
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 856.
DOI: https://doi.org/10.1158/1538-7445.AM2021-856
Published: 01 July 2021
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Journal Articles

Abstract 3377: NSCLC subtype-associated molecular and cellular alterations in the normal-appearing bronchial epithelium

Xingyi Shi, Jiarui Zhang, Steven Callori, Joshua Campbell, Denise Fine, Yaron Gesthalter, Gang Liu, Xiaohui Xiao, Avrum Spira, Marc Lenburg, Jennifer Beane
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3377.
DOI: https://doi.org/10.1158/1538-7445.AM2020-3377
Published: 15 August 2020
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Abstract LB-005: Allosteric SHP2 phosphatase inhibition: Multiple mechanisms and chemotypes

Matthew J. LaMarche, Jeff Bagdanoff, Mike Acker, Ying-Nan Chen, Homan Chan, Michael Dore, Brant Firestone, Michelle Fodor, Jorge Garcia-Fortanet, Murphy Hentemann, Mitsunori Kato, Robert Koenig, Laura La Bonte, Shumei Liu, Movarid Mohseni, Rukundo Ntaganda, Patrick Sarver, Troy Smith, Martin Sendzik, Travis Stams, Stan Spence, Chris Towler, Hongyun Wang, Ping Wang, Sarah Williams, Zhouliang Chen, Huaixiang Hao, Gang Liu, Chen Liu, Eric McNeill, Bing Yu
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-005.
DOI: https://doi.org/10.1158/1538-7445.AM2019-LB-005
Published: 01 July 2019
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Abstract 660: The molecular characterization of a murine lung premalignancy model for lung cancer interception

Sarah A. Mazzilli, Kahkeshan Hijazi, Riley Pihl, Anna Belkina, Xiaohui Zhang, Gang Liu, Marc Lenburg, Christopher Stevenson, Avrum Spira, Jennifer Beane
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 660.
DOI: https://doi.org/10.1158/1538-7445.AM2019-660
Published: 01 July 2019
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Journal Articles

Abstract 3393: Altered immune response in the transcriptome of patients with lung cancer

Kahkeshan Hijazi, Julian Lel, Ehab Billatos, Elizabeth Moses, Christopher S. Stevenson, Matthew V. Lorenzi, Gang Liu, Joshua D. Campbell, Yusuke Koga, Jiarui Zhang, Fenghai Duan, Helga Marques, Marc E. Lenburg, Avrum E. Spira, Jennifer Beane
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3393.
DOI: https://doi.org/10.1158/1538-7445.AM2019-3393
Published: 01 July 2019
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Journal Articles

Abstract 3530: Gene expression alterations associated with histologic aggressiveness in stage I lung adenocarcinomas

Jiarui Zhang, Eric Burks, Jennifer Beane, Travis Sullivan, Gang Liu, Steven Dubinett, Marc Lenburg, Avrum Spira
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3530.
DOI: https://doi.org/10.1158/1538-7445.AM2019-3530
Published: 01 July 2019
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Journal Articles

Abstract 3: Discovery and optimization of small molecule Bax activators for cancer therapy

Gang Liu, Hyejin Kim, Chunyong Ding, Zhuo Yu, Hong Wang, Haiying Chen, Qiang Shen, Jia Zhou
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3.
DOI: https://doi.org/10.1158/1538-7445.AM2019-3
Published: 01 July 2019
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Journal Articles

Abstract 3248: Genomic characterization of premalignant lung squamous cell carcinoma lesions

Joshua D. Campbell, Xijun Zhang, Catalina Perdomo, Sarah Mazzilli, Yaron Geshalter, Samjot S. Dhillon, Gang Liu, Sherry Zhang, Hanqiao Liu, Jessica Vick, Christopher Moy, Stefano Monti, Evan Johnson, Matthew Meyerson, Matthew Wilkerson, Clifton Dalgard, Suso Platero, Chris Stevenson, Marc Lenburg, Mary Reid, Jennifer Beane, Avrum Spira
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3248.
DOI: https://doi.org/10.1158/1538-7445.AM2018-3248
Published: 01 July 2018
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Journal Articles

Abstract 2808: Simultaneous inhibition of SHP2 phosphatase at two allosteric sites

Michelle Fodor, Edmund Price, Ping Wang, Hengyu Lu, Andreea Argintaru, Zhouliang Chen, Meir Glick, Huai-Xiang Hao, Mitsunori Kato, Robert Koenig, Jonathan R. LaRochelle, Gang Liu, Eric McNeill, Dyuti Majumdar, Gisele Nishiguchi, Lawrence Perez, Greg Paris, Christopher Quinn, Timothy Ramsey, Martin Sendzik, Michael Shultz, Sarah Williams, Travis Stams, Stephen C. Blacklow, Matthew J. LaMarche, Michael G. Acker
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2808.
DOI: https://doi.org/10.1158/1538-7445.AM2018-2808
Published: 01 July 2018
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Journal Articles

Abstract 2531: Diagnostic evaluation of indeterminate pulmonary nodules via rna-seq of bronchial epithelium

Xingyi Shi, Ehab Billatos, Jiarui Zhang, Jennifer Beane, Elizabeth Moses, Gang Liu, Christopher Stevenson, Marc E. Lenburg, Avrum Spira
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2531.
DOI: https://doi.org/10.1158/1538-7445.AM2018-2531
Published: 01 July 2018
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Abstract 2534: Single-cell RNA sequencing reveals lung cancer-associated alterations in bronchial cell subpopulations in the mainstem bronchus

Xingyi Shi, Grant Duclos, Joshua Campbell, Yaron Gesthalter, Patrick Autissier, Yves M. Dumas, Robert Terrano, Gang Liu, Marc E. Lenburg, Avrum Spira, Jennifer Beane
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2534.
DOI: https://doi.org/10.1158/1538-7445.AM2018-2534
Published: 01 July 2018
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Journal Articles

Abstract 1655: Discovery and development of IACS-010759, a novel inhibitor of Complex I currently in phase I studies to exploit oxidative phosphorylation dependency in acute myeloid leukemia and solid tumors

Maria Emilia Di Francesco, Joseph R. Marszalek, Timothy McAfoos, Christopher L. Carroll, Zhijun Kang, Gang Liu, Jay P. Theroff, Jennifer P. Bardenhager, Madhavi L. Bandi, Jennifer R. Molina, Sonal Gera, Marina Protopopova, Yuting Sun, Mary K. Geck Do, Ningping Feng, Jason P. Gay, Florian Muller, Marina Konopleva, Funda Meric-Bernstam, Carlo Toniatti, Timothy P. Heffernan, Giulio F. Draetta, Philip Jones
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1655.
DOI: https://doi.org/10.1158/1538-7445.AM2018-1655
Published: 01 July 2018
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Journal Articles

Abstract B18: The carcinogen-induced NTCU model: A preclinical mouse model for lung cancer interception

Sarah Mazzilli, Sherry Zhang, Gang Liu, Marc Lenburg, Avrum Spira, Jennifer Beane
Journal: Cancer Research
Cancer Res (2018) 78 (10_Supplement): B18.
DOI: https://doi.org/10.1158/1538-7445.MOUSEMODELS17-B18
Published: 14 May 2018
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Abstract 1194: Neutralization of IGF-I and -II ligands with the fully humanized bispecific monoclonal antibody xentuzumab inhibits AR-V7-induced enzalutamide resistance in castration-resistant prostate cancer

Gang Liu, Holly M. Nguyen, Kristine van Maltzan, Shihua Sun, Cynthia Sprenger, Ulrike Weyer-Czernilofsky, Eva Corey, Stephen R. Plymate
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1194.
DOI: https://doi.org/10.1158/1538-7445.AM2017-1194
Published: 01 July 2017
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