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Galina Kuznetsov
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Journal Articles

Abstract 275: ER-886046, an antagonist of PGE2 receptor type-4, induces an effective antitumor immune response in mice by attenuating intratumoral MDSCs and TAMs

Diana I. Albu, Zichun Wang, Jiayi Wu, Kuan-chun Huang, Wei Li, Diana Liu, Galina Kuznetsov, Qian Chen, Xingfeng Bao, Mary Woodall-Jappe
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 275.
https://doi.org/10.1158/1538-7445.AM2015-275
Published: 01 August 2015
View article titled, Abstract 275: ER-886046, an antagonist of PGE2 receptor type-4, induces an effective antitumor immune response in mice by attenuating intratumoral MDSCs and TAMs
Journal Articles

Abstract P5-06-03: Combination of the PARP inhibitor E7449 with eribulin +/- carboplatin in preclinical models of triple negative breast cancer

Sharon McGonigle, Jiayi Wu, Donna Kolber-Simonds, Natalie C Twine, Jue-lon Shie, Noel Taylor, Sergei Agoulnik, Zoltan Dezso, Shannon McGrath, Mark Matijevic, Shanqin Xu, Galina Kuznetsov, Mary Woodall-Jappe, Kenichi Nomoto
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P5-06-03.
https://doi.org/10.1158/1538-7445.SABCS14-P5-06-03
Published: 01 May 2015
View article titled, Abstract P5-06-03: Combination of the PARP inhibitor E7449 with eribulin +/- carboplatin in preclinical models of triple negative breast cancer
Journal Articles

Abstract 2733: Antitumor activity of the PARP inhibitor E7449 in Ewing's sarcoma

Sharon McGonigle, Zhihong Chen, Jingzang Tao Miu, Kuan-Chun Huang, Donna Kolber-Simonds, Nanding Zhao, Natalie C. Twine, Qiongfang Cao, Galina Kuznetsov, Shanqin Xu, Kenichi Nomoto
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2733.
https://doi.org/10.1158/1538-7445.AM2014-2733
Published: 01 October 2014
View article titled, Abstract 2733: Antitumor activity of the PARP inhibitor E7449 in Ewing's sarcoma
Journal Articles

Abstract 4502: Eribulin alters vascular function in human triple-negative (TN) breast MX-1 and MDA-MB-231 tumor xenograft models as measured by DCE-MRI.

Paul J. McCracken, Ken Ito, Mamoru Yanagimachi, Xavier Tizon, Peggy Provent, Shanqin Xu, Namita Kumar, Denice Welsh, Tyler J. Teceno, Galina Kuznetsov, Yasuhiro Funahashi
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4502.
https://doi.org/10.1158/1538-7445.AM2013-4502
Published: 15 April 2013
View article titled, Abstract 4502: Eribulin alters vascular function in human triple-negative (TN) breast MX-1 and MDA-MB-231 tumor xenograft models as measured by DCE-MRI.
Journal Articles

Abstract 4126: Optimization of clinical sample collection for detection of c-Met phosphorylation

Takayuki Nakagawa, Namita Kumar, Galina Kuznetsov
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4126.
https://doi.org/10.1158/1538-7445.AM2011-4126
Published: 15 April 2011
View article titled, Abstract 4126: Optimization of clinical sample collection for detection of c-Met phosphorylation
Journal Articles

Abstract #3690: In vitro antiproliferative activity of natural product-based MEK1 inhibitor E6201 against V600E BRAF-mutated cancer cell lines

Kenichi Nomoto, John Wang, Jiayi Wu, Sergei Agoulnik, Galina Kuznetsov, Murray Towle, Matthew Schnaderbeck, Fabian Gusovsky, Hiroshi Shirota, Bruce Littlefield
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3690.
Published: 01 May 2009
View article titled, Abstract #3690: In vitro antiproliferative activity of natural product-based MEK1 inhibitor E6201 against V600E BRAF-mutated cancer cell lines
Journal Articles

Abstract #3687: In vivo anticancer activity of E6201, a novel MEK1 inhibitor, against BRAF-mutated human cancer xenografts

Jiayi Wu, Kenichi Nomoto, John Wang, Galina Kuznetsov, Sergei Agoulnik, Edgar Shuck, Nancy Wong, Murray Towle, Matthew Schnaderbeck, Sara Wu, Bruce Littlefield
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3687.
Published: 01 May 2009
View article titled, Abstract #3687: In vivo anticancer activity of E6201, a novel MEK1 inhibitor, against BRAF-mutated human cancer xenografts
Journal Articles

Potent in vitro and in vivo anticancer activities of desmethyl, desamino (DMDA)-pateamine A, an analog of marine natural product pateamine A

Galina Kuznetsov, Qunli Xu, Karen TenDyke, Junke Liu, Murray Towle, Nanding Zhao, Joanne Marsh, Sergei Agoulnik, Natalie Twine, Lana Parent, Zhihong Chen, Yimin Jiang, Huiming Zhang, Hong Du, Roch Boivin, John (Yuan) Wang, Daniel Romo, Bruce Littlefield
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5702.
Published: 01 May 2008
View article titled, Potent <em>in vitro</em> and <em>in vivo</em> anticancer activities of desmethyl, desamino (DMDA)-pateamine A, an analog of marine natural product pateamine A
Journal Articles

Synthetic analogs of the marine natural product hemiasterlin: Optimization and discovery of E7974, a novel and potent antitumor agent

James J. Kowalczyk, Shawn E. R. Schiller, Mark Spyvee, Hu Yang, Boris M. Seletsky, Christina J. Shaffer, Veronique Marceau, Ye Yao, Galina Kuznetsov, Karen Tendyke, Diana Liu, Cheryl Rowell, Bruce A. Littlefield, Edward M. Suh
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 282.
Published: 01 May 2005
View article titled, Synthetic analogs of the marine natural product hemiasterlin: Optimization and discovery of E7974, a novel and potent antitumor agent
Journal Articles

In vitro and in vivo antitumor activities of novel hemiasterlin analog E7974

Galina Kuznetsov, Karen Tendyke, Murray J. Towle, Hongsheng Cheng, Diana Liu, Cheryl Rowell, Jiayi Wu, James J. Kowalczyk, Veronique Marceau, Silvio Campagna, Shawn E. R. Schiller, Bruce A. Littlefield
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 809.
Published: 01 May 2005
View article titled, <em>In vitro</em> and <em>in vivo</em> antitumor activities of novel hemiasterlin analog E7974
Journal Articles

Tubulin-based antimitotic mechanism of novel hemiasterlin analog E7974

Galina Kuznetsov, Murray J. Towle, Junke Liu, Hongsheng Cheng, Karen Tendyke, Jim J. Kowalczyk, Silvio Campagna, Bruce A. Littlefield
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 810.
Published: 01 May 2005
View article titled, Tubulin-based antimitotic mechanism of novel hemiasterlin analog E7974
Journal Articles

Induction of Morphological and Biochemical Apoptosis following Prolonged Mitotic Blockage by Halichondrin B Macrocyclic Ketone Analog E7389

Galina Kuznetsov, Murray J. Towle, Hongsheng Cheng, Takanori Kawamura, Karen TenDyke, Diana Liu, Yoshito Kishi, Melvin J. Yu, Bruce A. Littlefield
Journal: Cancer Research
Cancer Res (2004) 64 (16): 5760–5766.
https://doi.org/10.1158/0008-5472.CAN-04-1169
Published: 16 August 2004
View article titled, Induction of Morphological and Biochemical Apoptosis following Prolonged Mitotic Blockage by Halichondrin B Macrocyclic Ketone Analog E7389
Open the PDF for Induction of Morphological and Biochemical Apoptosis following Prolonged Mitotic Blockage by Halichondrin B Macrocyclic Ketone Analog E7389 in another window
Journal Articles

In Vitro and In Vivo Anticancer Activities of Synthetic Macrocyclic Ketone Analogues of Halichondrin B

Murray J. Towle, Kathleen A. Salvato, Jacqueline Budrow, Bruce F. Wels, Galina Kuznetsov, Kimberley K. Aalfs, Susan Welsh, Wanjun Zheng, Boris M. Seletsky, Monica H. Palme, Gregory J. Habgood, Lori A. Singer, Lucian V. DiPietro, Yuan Wang, Jack J. Chen, David A. Quincy, Ashley Davis, Kentaro Yoshimatsu, Yoshito Kishi, Melvin J. Yu, Bruce A. Littlefield
Journal: Cancer Research
Cancer Res (2001) 61 (3): 1013–1021.
Published: 02 February 2001
View article titled, <em>In Vitro</em> and <em>In Vivo</em> Anticancer Activities of Synthetic Macrocyclic Ketone Analogues of Halichondrin B
Open the PDF for <em>In Vitro</em> and <em>In Vivo</em> Anticancer Activities of Synthetic Macrocyclic Ketone Analogues of Halichondrin B in another window