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Journal Articles

Abstract 718: Significantly strong protective efficacy of silibinin against basal cell carcinoma growth and progression

Sandeep Paudel, Komal Raina, Vasundhara R. Tiku, Akhilendra Maurya, David J. Orlicky, Zhiying You, Cindy M. Rigby, Gagan Deep, Rama Kant, Bupinder Raina, Chapla Agarwal, Rajesh Agarwal
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 718.
https://doi.org/10.1158/1538-7445.AM2022-718
Published: 15 June 2022
View article titled, Abstract 718: Significantly strong protective efficacy of silibinin against basal cell carcinoma growth and progression
Journal Articles

Abstract 5822: Leptin modulated microRNA-628-5p targets Jagged1 and inhibits prostate cancer hallmarks

Leslimar Rios Colon, Juliet Chijioke, Suryakant Niture, Zainab Afzal, Qi Qi, Anvesha Srivastava, Malathi Ramalinga, Habib Kedir, Patrice Cagle, Elena Arthur, Gagan Deep, Simeng Suy, Sean Collins, Deepak Kumar
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5822.
https://doi.org/10.1158/1538-7445.AM2022-5822
Published: 15 June 2022
View article titled, Abstract 5822: Leptin modulated microRNA-628-5p targets Jagged1 and inhibits prostate cancer hallmarks
Journal Articles

Abstract P2-12-24: Exosomal metabolic signatures are associated with differential response to neoadjuvant chemotherapy in patients with breast cancer

Shriya Joshi, Chakravarthy Garalapati, Shristi Bhattarai, Darshan Shimoga Chandrashekar, Sooryanarayana Varambally, Gagan Deep, Ritu Aneja
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P2-12-24.
https://doi.org/10.1158/1538-7445.SABCS21-P2-12-24
Published: 15 February 2022
View article titled, Abstract P2-12-24: Exosomal metabolic signatures are associated with differential response to neoadjuvant chemotherapy in patients with breast cancer
Journal Articles

Abstract 2653: Usefulness of plasma exosomes to characterize hypoxic phenotype in primary prostate tumors

Gatikrushna Panigrahi, Yixin Su, Leslimar Rios-Colon, Taylor Peak, Kiran Sai, Prakash Praharaj, Jingyun Lee, Cristina Furdui, Ashok Hemal, Deepak Kumar, Gagan Deep
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2653.
https://doi.org/10.1158/1538-7445.AM2019-2653
Published: 01 July 2019
View article titled, Abstract 2653: Usefulness of plasma exosomes to characterize hypoxic phenotype in primary prostate tumors
Journal Articles

Abstract 770: MiR628-5p targets Jagged 1 and inhibits growth, stemness and invasiveness of advanced prostate cancer cells

Leslimar Rios-Colon, Juliet Chijioke, Anvesha Srivastava, Malathi Ramalinga, Habib Kedir, Elena Arthur, Patrice Cagle, Gagan Deep, Deepak Kumar
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 770.
https://doi.org/10.1158/1538-7445.AM2019-770
Published: 01 July 2019
View article titled, Abstract 770: MiR628-5p targets Jagged 1 and inhibits growth, stemness and invasiveness of advanced prostate cancer cells
Journal Articles

Abstract 5088: Silibinin inhibits UVB-induced promotion and progression of microscopic basal cell carcinoma formation via targeting bone morphogenic protein 2

Cynthia M. Rigby, Gagan Deep, Anil K. Jain, David J. Orlicky, Chapla Agarwal, Komal Raina, Rajesh Agarwal
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 5088.
https://doi.org/10.1158/1538-7445.AM2019-5088
Published: 01 July 2019
View article titled, Abstract 5088: Silibinin inhibits UVB-induced promotion and progression of microscopic basal cell carcinoma formation via targeting bone morphogenic protein 2
Journal Articles

Abstract 1095: Insulin-like Growth Factor Binding Protein-3 (IGFBP-3) regulates mitochondrial dynamics, EMT and angiogenesis in progression of prostate cancer

Arpit Dheeraj, Dhanir Tailor, Gagan Deep, Rana P. Singh
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1095.
https://doi.org/10.1158/1538-7445.AM2018-1095
Published: 01 July 2018
View article titled, Abstract 1095: Insulin-like Growth Factor Binding Protein-3 (IGFBP-3) regulates mitochondrial dynamics, EMT and angiogenesis in progression of prostate cancer
Journal Articles

Abstract 2437: Novel metabolic adaptations support proliferation of African American prostate cancer cells under hypoxia

Gati Panigrahi, Prakash Praharaj, Kiran Sai, Gargi Mahapatra, Taylor Peak, Sierra Patterson, Hakeem Oufkir, Anthony Molina, Steven Kridel, Gagan Deep
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2437.
https://doi.org/10.1158/1538-7445.AM2018-2437
Published: 01 July 2018
View article titled, Abstract 2437: Novel metabolic adaptations support proliferation of African American prostate cancer cells under hypoxia
Journal Articles

Abstract 1338: Exosome secretion promotes proliferation of African American prostate cancer cells under hypoxia: Role of HIF2A and RAB signaling

Gatikrushna Panigrahi, Taylor C. Peak, Sierra L. Patterson, Nicole Kasica, Ravi Singh, Ashok Hemal, Gagan Deep
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1338.
https://doi.org/10.1158/1538-7445.AM2017-1338
Published: 01 July 2017
View article titled, Abstract 1338: Exosome secretion promotes proliferation of African American prostate cancer cells under hypoxia: Role of HIF2A and RAB signaling
Journal Articles

Abstract 1268: Bitter melon efficacy against human pancreatic cancer cells: possible involvement of cellular stemness and metabolome targets

Deepanshi Dhar, Gagan Deep, Sushil Kumar, Chapla Agarwal, Natalie Serkova, Michael Wempe, Komal Raina, Rajesh Agarwal
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1268.
https://doi.org/10.1158/1538-7445.AM2017-1268
Published: 01 July 2017
View article titled, Abstract 1268: Bitter melon efficacy against human pancreatic cancer cells: possible involvement of cellular stemness and metabolome targets
Journal Articles

Abstract 3187: Role of exosome secretion in the survival of enzalutamide-resistant prostate cancer cells: Syntaxin 6 as a novel therapeutic target

Taylor C. Peak, Nicole P. Kasica, Gati K. Panigrahi, Sierra L. Patterson, Ravi Singh, Ashok K. Hemal, Rhonda L. Bitting, Gagan Deep
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3187.
https://doi.org/10.1158/1538-7445.AM2017-3187
Published: 01 July 2017
View article titled, Abstract 3187: Role of exosome secretion in the survival of enzalutamide-resistant prostate cancer cells: Syntaxin 6 as a novel therapeutic target
Journal Articles

Abstract 1055: CPT1A-mediated lipid catabolism modulates growth, AR expression and hypoxia survival of prostate cancer

Isabel R. Schlaepfer, Gagan Deep, Rajesh Agarwal, Zhiyong Zhang, Maren Salzmann-Sullivan, Lih-Jen Su, Thomas Flaig
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1055.
https://doi.org/10.1158/1538-7445.AM2016-1055
Published: 15 July 2016
View article titled, Abstract 1055: CPT1A-mediated lipid catabolism modulates growth, AR expression and hypoxia survival of prostate cancer
Journal Articles

Abstract 5236: Bitter melon juice causes strong efficacy towards pancreatic cancer stem cells by modulating the hedgehog signaling pathway

Rajesh Agarwal, Deepanshi Dhar, Chapla Agarwal, Gagan Deep
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5236.
https://doi.org/10.1158/1538-7445.AM2016-5236
Published: 15 July 2016
View article titled, Abstract 5236: Bitter melon juice causes strong efficacy towards pancreatic cancer stem cells by modulating the hedgehog signaling pathway
Journal Articles

Abstract 3339: Silibinin improves radiotherapeutic efficacy in prostate cancer by reducing IR-induced toxicity and EMT

Dhanya K. Nambiar, Paulraj Rajamani, Anil Jain, Gagan Deep, Rajesh Agarwal, Rana P. Singh
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3339.
https://doi.org/10.1158/1538-7445.AM2015-3339
Published: 01 August 2015
View article titled, Abstract 3339: Silibinin improves radiotherapeutic efficacy in prostate cancer by reducing IR-induced toxicity and EMT
Journal Articles

Abstract 107: Lipid metabolism inhibitors enhance glycolysis and FDG-PET imaging of prostate cancer tumors

Isabel R. Schlaepfer, Colton T. Pac, Natalie J. Serkova, Gagan Deep, Rajesh Agarwal, Scott D. Cramer, Robert H. Eckel, L. Michael Glode
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 107.
https://doi.org/10.1158/1538-7445.AM2014-107
Published: 01 October 2014
View article titled, Abstract 107: Lipid metabolism inhibitors enhance glycolysis and FDG-PET imaging of prostate cancer tumors
Journal Articles

Abstract 1012: Procyanidin B2 3,3″-di-O-gallate (B2G2), a biologically active constituent of grape seed extract, inhibits angiogenesis targeting multiple molecular pathways

Rahul Kumar, Gagan Deep, Michael Wempe, Rajesh Agarwal, Chapla Agarwal
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1012.
https://doi.org/10.1158/1538-7445.AM2014-1012
Published: 01 October 2014
View article titled, Abstract 1012: Procyanidin B2 3,3″-di-O-gallate (B2G2), a biologically active constituent of grape seed extract, inhibits angiogenesis targeting multiple molecular pathways
Journal Articles

Abstract 698A: Bitter melon juice targets molecular mechanisms underlying gemcitabine resistance in pancreatic cancer cells

Ranganatha Somasagara, Gagan Deep, Sangeeta Shrotriya, Manisha Patel, Chapla Agarwal, Rajesh Agarwal
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 698A.
https://doi.org/10.1158/1538-7445.AM2014-698A
Published: 01 October 2014
View article titled, Abstract 698A: Bitter melon juice targets molecular mechanisms underlying gemcitabine resistance in pancreatic cancer cells
Journal Articles

Abstract 2452: Silibinin inhibits lipid metabolism by primarily targeting the master regulator sterol response element binding protein 1 (SREBP1) in prostate cancer cells

Dhanya K. Nambiar, Gagan Deep, Rana P. Singh, Chapla Agarwal, Rajesh Agarwal
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2452.
https://doi.org/10.1158/1538-7445.AM2014-2452
Published: 01 October 2014
View article titled, Abstract 2452: Silibinin inhibits lipid metabolism by primarily targeting the master regulator sterol response element binding protein 1 (SREBP1) in prostate cancer cells
Journal Articles

Abstract 4114: Silibinin inhibits hypoxia-induced proliferation, angiogenesis and lipogenesis in prostate cancer cells both in vitro and in vivo

Gagan Deep, Anand M. Ramteke, Dhanya K. Nambiar, Anil K. Jain, Natalie J. Serkova, Chapla Agarwal, Rajesh Agarwal
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4114.
https://doi.org/10.1158/1538-7445.AM2014-4114
Published: 01 October 2014
View article titled, Abstract 4114: Silibinin inhibits hypoxia-induced proliferation, angiogenesis and lipogenesis in prostate cancer cells both in vitro and in vivo
Journal Articles

Abstract C73: Src-beta catenin-SNAI1 axis is critical for the stemness and bone metastasis of E-cadherin-lacking prostate cancer cells

Gagan Deep, Anil K. Jain, Samiha Mateen, Kavitha C. Vijendra, Subhash C. Gangar, Chapla Agarwal, Rajesh Agarwal
Journal: Cancer Research
Cancer Res (2013) 73 (3_Supplement): C73.
https://doi.org/10.1158/1538-7445.TIM2013-C73
Published: 01 May 2014
View article titled, Abstract C73: Src-beta catenin-SNAI1 axis is critical for the stemness and bone metastasis of E-cadherin-lacking prostate cancer cells