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Gadi Lalazar
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Journal Articles

Abstract A068 Emerging therapies for the treatment of the fusion protein driven cancer, fibrolamellar carcinoma

Mahsa Shirani, Michael Tomasini, Christoph Neumayer, Denise Ng, Gadi Lalazar, Bassem Shebl, Philip Coffino, Barbara A. Lyons, Sanford Simon
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement): A068.
https://doi.org/10.1158/1538-7445.PEDIATRIC24-A068
Published: 05 September 2024
View article titled, Abstract A068 Emerging therapies for the treatment of the fusion protein driven cancer, fibrolamellar carcinoma
Journal Articles

Abstract B022: Precision medicine for the fusion protein driven cancer, fibrolamellar carcinoma (FLC): Beyond sequencing

Sanford Simon, Mahsa Shirani, David Requena, Denise Ng, Gadi Lalazar, Solomon Levin, Michael S. Torbenson, Aatur D. Singhi, Henrik Molina, Charles M. Rice, Philip Coffino, Barbara A. Lyons
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement): B022.
https://doi.org/10.1158/1538-7445.PEDIATRIC24-B022
Published: 05 September 2024
View article titled, Abstract B022: Precision medicine for the fusion protein driven cancer, fibrolamellar carcinoma (FLC): Beyond sequencing
Journal Articles

Increased Protein Kinase A Activity Induces Fibrolamellar Hepatocellular Carcinoma Features Independent of DNAJB1

Mahsa Shirani, Solomon Levin, Bassem Shebl, David Requena, Tova M. Finkelstein, Daniel S. Johnson, Denise Ng, Gadi Lalazar, Søren Heissel, Peter Hojrup, Henrik Molina, Ype P. de Jong, Charles M. Rice, Aatur D. Singhi, Michael S. Torbenson, Philip Coffino, Barbara Lyons, Sanford M. Simon
Journal: Cancer Research
Cancer Res (2024) 84 (16): 2626–2644.
https://doi.org/10.1158/0008-5472.CAN-23-4110
Published: 15 August 2024
View article titled, Increased Protein Kinase A Activity Induces Fibrolamellar Hepatocellular Carcinoma Features Independent of DNAJB1
Open the PDF for Increased Protein Kinase A Activity Induces Fibrolamellar Hepatocellular Carcinoma Features Independent of DNAJB1 in another window
Includes: Supplementary data
Journal Articles

Abstract 1516: Bulk and spatial single-cell transcriptomic characterization of fibrolamellar hepatocellular carcinoma

David Requena, Aldhair Medico, Luis F. Soto, Mahsa Shirani, James A. Saltsman, Gadi Lalazar, Michael P. LaQuaglia, Sanford M. Simon
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1516.
https://doi.org/10.1158/1538-7445.AM2023-1516
Published: 04 April 2023
View article titled, Abstract 1516: Bulk and spatial single-cell transcriptomic characterization of fibrolamellar hepatocellular carcinoma
Journal Articles

Abstract 3888: Targeting Bcl-xL in fibrolamellar hepatocellular carcinoma

Bassem Shebl, Gadi Lalazar, Denise Ng, Tova Finkelstein, Guangrong Zheng, Peiyi Zhang, Carly Rosemore, Michael Ortiz, Daohong Zhou, Sanford Simon, Philip Coffino
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3888.
https://doi.org/10.1158/1538-7445.AM2022-3888
Published: 15 June 2022
View article titled, Abstract 3888: Targeting Bcl-xL in fibrolamellar hepatocellular carcinoma
Journal Articles

Abstract 3905: Human liver organoids for disease modeling of fibrolamellar hepatocellular carcinoma

Nicole J. Croteau, David Requena, Gadi Lalazar, Denise Ng, Solomon Levin, Bassem Shebl, Ruisi Wang, William J. Hammond, James A. Saltsman, Helmuth Gehart, Hans Clevers, Michael P. LaQuaglia, Sanford Simon
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3905.
https://doi.org/10.1158/1538-7445.AM2020-3905
Published: 15 August 2020
View article titled, Abstract 3905: Human liver organoids for disease modeling of fibrolamellar hepatocellular carcinoma
Journal Articles

Abstract A51: Advances in the etiology and therapeutics of a lethal childhood cancer, fibrolamellar hepatocellular carcinoma

Gadi Lalazar, Melissa Jarmel, Ruisi Wang, Michael Tomasini, David Requena, Denise Ng, Sanford M. Simon
Journal: Cancer Research
Cancer Res (2020) 80 (14_Supplement): A51.
https://doi.org/10.1158/1538-7445.PEDCA19-A51
Published: 15 July 2020
View article titled, Abstract A51: Advances in the etiology and therapeutics of a lethal childhood cancer, fibrolamellar hepatocellular carcinoma
Journal Articles

PSMD5 Inactivation Promotes 26S Proteasome Assembly during Colorectal Tumor Progression

Avi Levin, Adi Minis, Gadi Lalazar, Jose Rodriguez, Hermann Steller
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (13): 3458–3468.
https://doi.org/10.1158/0008-5472.CAN-17-2296
Published: 01 July 2018
View article titled, PSMD5 Inactivation Promotes 26S Proteasome Assembly during Colorectal Tumor Progression
Open the PDF for PSMD5 Inactivation Promotes 26S Proteasome Assembly during Colorectal Tumor Progression in another window
Journal Articles

Abstract 4730: Molecular analysis of the pediatric cancer fibrolamellar hepatocellular carcinoma

Elana P. Simon, Joshua N. Honeyman, David G. Darcy, Brad R. Rosenberg, Iris I. Lim, Jennifer M. Murphy, Ben Farber, Gadi Lalazar, Catherine Freije, Michael P. La Quaglia, Sanford M. Simon
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4730.
https://doi.org/10.1158/1538-7445.AM2015-4730
Published: 01 August 2015
View article titled, Abstract 4730: Molecular analysis of the pediatric cancer fibrolamellar hepatocellular carcinoma