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Gabriele Multhoff
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Journal Articles

Abstract 5426: Down-regulation of cancer metabolism enhances radiosensitivity by impairing the heat shock response

Melissa Schwab, Katharina Thunborg, Omid Azimzadeh, Christine von Toerne, Maxim Shevtsov, Masa Zdralevic, Jacques Pouyssegur, Kathrin Renner, Marina Kreutz, Peter Vaupel, Gabriele Multhoff
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5426.
https://doi.org/10.1158/1538-7445.AM2022-5426
Published: 15 June 2022
View article titled, Abstract 5426: Down-regulation of cancer metabolism enhances radiosensitivity by impairing the heat shock response
Journal Articles

Abstract 2878: Granzyme B functionalized nanocarriers targeting membrane-bound Hsp70 for multimodal cancer therapies

Maxim Shevtsov, Susanne Kaesler, Stefan Stangl, Luidmila Yakovleva, Ruslana Tagaeva, Yaroslav Marchenko, Boris Nikolaev, William Khachatryan, Oleg Galibin, Emil Pitkin, Gabriele Multhoff
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2878.
https://doi.org/10.1158/1538-7445.AM2020-2878
Published: 15 August 2020
View article titled, Abstract 2878: Granzyme B functionalized nanocarriers targeting membrane-bound Hsp70 for multimodal cancer therapies
Journal Articles

Abstract LB-076: Targeted Natural Killer (NK) cell based adoptive immunotherapy for the treatment of patients with non-small cell lung cancer (NSCLC) after radiochemotherapy - results of a randomized phase II clinical trial (NSCLC-TKD/IL-2) (Eudra-CT Number 2008-002130-30)

Gabriele Multhoff, Stephanie E. Combs, Sophie Seier, Stefan Stangl, Wolfgang Sievert, Maxim Shevtsov, Christiane Blankenstein, Martin Hildebrandt, Konrad Kokowski, Matthias Hautmann, Hubert Hautmann, Claus Roedel, Rainer Fietkau, Rudolf M. Huber, Bernhard Haller, Christina Ertl, Michal Devecka, Robert Offner, Norbert Ahrens
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): LB-076.
https://doi.org/10.1158/1538-7445.AM2020-LB-076
Published: 15 August 2020
View article titled, Abstract LB-076: Targeted Natural Killer (NK) cell based adoptive immunotherapy for the treatment of patients with non-small cell lung cancer (NSCLC) after radiochemotherapy - results of a randomized phase II clinical trial (NSCLC-TKD/IL-2) (Eudra-CT Number 2008-002130-30)
Journal Articles

Abstract 4258: Molecular spectral CT imaging of Hsp70 positive solid tumors

Stefan Stangl, Maxim Shevtsov, Caroline Werner, Wolfgang Sievert, Gabriele Multhoff
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4258.
https://doi.org/10.1158/1538-7445.AM2020-4258
Published: 15 August 2020
View article titled, Abstract 4258: Molecular spectral CT imaging of Hsp70 positive solid tumors
Journal Articles

Abstract LB-016: Radiochemotherapy combined with NK cells followed by a second-line PD-1 inhibition in a patients with NSCLC stage IIIb induces long-term tumor control

Gabriele Multhoff, Konrad Kokowski, Martin Hildebrandt, Peter Vaupel, Stefan Stangl
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-016.
https://doi.org/10.1158/1538-7445.AM2019-LB-016
Published: 01 July 2019
View article titled, Abstract LB-016: Radiochemotherapy combined with NK cells followed by a second-line PD-1 inhibition in a patients with NSCLC stage IIIb induces long-term tumor control
Journal Articles

Preclinical Evaluation of the Hsp70 Peptide Tracer TPP-PEG24-DFO[89Zr] for Tumor-Specific PET/CT Imaging

Stefan Stangl, Lorenzo Tei, Francesco De Rose, Sybille Reder, Jonathan Martinelli, Wolfgang Sievert, Maxim Shevtsov, Rupert Öllinger, Roland Rad, Markus Schwaiger, Calogero D'Alessandria, Gabriele Multhoff
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (21): 6268–6281.
https://doi.org/10.1158/0008-5472.CAN-18-0707
Published: 01 November 2018
View article titled, Preclinical Evaluation of the Hsp70 Peptide Tracer TPP-PEG<sub>24</sub>-DFO[<sup>89</sup>Zr] for Tumor-Specific PET/CT Imaging
Open the PDF for Preclinical Evaluation of the Hsp70 Peptide Tracer TPP-PEG<sub>24</sub>-DFO[<sup>89</sup>Zr] for Tumor-Specific PET/CT Imaging in another window
Includes: Supplementary data
Journal Articles

Selective In Vivo Imaging of Syngeneic, Spontaneous, and Xenograft Tumors Using a Novel Tumor Cell–Specific Hsp70 Peptide-Based Probe

Stefan Stangl, Julia Varga, Bianca Freysoldt, Marija Trajkovic-Arsic, Jens T. Siveke, Florian R. Greten, Vasilis Ntziachristos, Gabriele Multhoff
Journal: Cancer Research
Cancer Res (2014) 74 (23): 6903–6912.
https://doi.org/10.1158/0008-5472.CAN-14-0413
Published: 30 November 2014
View article titled, Selective <em>In Vivo</em> Imaging of Syngeneic, Spontaneous, and Xenograft Tumors Using a Novel Tumor Cell–Specific Hsp70 Peptide-Based Probe
Open the PDF for Selective <em>In Vivo</em> Imaging of Syngeneic, Spontaneous, and Xenograft Tumors Using a Novel Tumor Cell–Specific Hsp70 Peptide-Based Probe in another window
Includes: Supplementary data
Journal Articles

Long-lasting in vivo cytolytic response of NK cells against HSP70-positive tumors

Valeria Milani, Beate Wagner, Rolf Issels, Gabriele Multhoff
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2842.
Published: 01 May 2008
View article titled, Long-lasting <em>in vivo</em> cytolytic response of NK cells against HSP70-positive tumors
Journal Articles

Heat Shock Protein 70 Surface-Positive Tumor Exosomes Stimulate Migratory and Cytolytic Activity of Natural Killer Cells

Robert Gastpar, Mathias Gehrmann, Maria A. Bausero, Alexzander Asea, Catharina Gross, Josef A. Schroeder, Gabriele Multhoff
Journal: Cancer Research
Cancer Res (2005) 65 (12): 5238–5247.
https://doi.org/10.1158/0008-5472.CAN-04-3804
Published: 15 June 2005
View article titled, Heat Shock Protein 70 Surface-Positive Tumor Exosomes Stimulate Migratory and Cytolytic Activity of Natural Killer Cells
Open the PDF for Heat Shock Protein 70 Surface-Positive Tumor Exosomes Stimulate Migratory and Cytolytic Activity of Natural Killer Cells in another window