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Journal Articles

Dysfunction of Poly (ADP-Ribose) Glycohydrolase Induces a Synthetic Lethal Effect in Dual Specificity Phosphatase 22-Deficient Lung Cancer Cells

Yuka Sasaki, Hiroaki Fujimori, Miyuki Hozumi, Takae Onodera, Tadashige Nozaki, Yasufumi Murakami, Kazuto Ashizawa, Kengo Inoue, Fumiaki Koizumi, Mitsuko Masutani

Cancer Res (2019) 79 (15): 3851–3861.

DOI: https://doi.org/10.1158/0008-5472.CAN-18-1037

Published: 01 August 2019

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Includes: Supplementary data

Journal Articles

Abstract 1792: Immune system pathway activation for prediction of the response to neoadjuvant chemotherapy in triple-negative breast cancer

Takeshi Sawada, Riet Hilhorst, Savithri Rangarajan, Masayuki Yoshida, Kenji Tamura, Rinie van Beuningen, Rob Ruijtenbeek, Hitoshi Tsuda, Fumiaki Koizumi

Cancer Res (2017) 77 (13_Supplement): 1792.

DOI: https://doi.org/10.1158/1538-7445.AM2017-1792

Published: 01 July 2017

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Journal Articles

Abstract 500: Prognostic impact of CTC detected using a novel fluidic cell microarray chip CTC detection system in patients with breast cancer

Cancer Res (2016) 76 (14_Supplement): 500.

DOI: https://doi.org/10.1158/1538-7445.AM2016-500

Published: 15 July 2016

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Journal Articles

Abstract 4808: Identification of a novel compound, MO2455, that induces poly(ADP-ribose) (PAR) accumulation and inhibits the growth of cancer cells in vitro and in vivo

Tatsu Shimoyama, Takeshi Sawada, Mari Akimoto, Yuka Sasaki, Hiroaki Fujimori, Yoshinobu Ishikawa, Tadashi Okawara, Tetsumi Irie, Takeji Takamura, Kenji Matsuno, Kengo Inoue, Mitsuko Masutani, Fumiaki Koizumi

Cancer Res (2016) 76 (14_Supplement): 4808.

DOI: https://doi.org/10.1158/1538-7445.AM2016-4808

Published: 15 July 2016

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Journal Articles

Abstract 1334: Chemotherapy regulated microRNA-125/HER2 pathway as a novel therapeutic target for trastuzumab-mediated cellular cytotoxicity in small-cell lung cancer

Shigehiro Yagishita, Yu Fujita, Yuichi Fujimoto, Fumiyuki Takahashi, Kazuhisa Takahashi, Tomohide Tamura, Fumiaki Koizumi

Cancer Res (2015) 75 (15_Supplement): 1334.

DOI: https://doi.org/10.1158/1538-7445.AM2015-1334

Published: 01 August 2015

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Journal Articles

Abstract 1605: Dielectrophoretic microwell array system for detection circulating tumor cells in patients with solid tumors and single cell analysis of detected circulating tumor cells

Takeshi Sawada, Atsushi Morimoto, Tatsu Shimoyama, Toshinari Yamashita, Toshifumi Mogami, Kazuki Iijima, Mayu Yunokawa, Shintaro Kanda, Yasuyuki Akiyama, Koji Katayama, Masaru Watanabe, Yasuhiro Koh, Kenji Tamura, Tomohide Tamura, Toru Futami, Fumiaki Koizumi

Cancer Res (2015) 75 (15_Supplement): 1605.

DOI: https://doi.org/10.1158/1538-7445.AM2015-1605

Published: 01 August 2015

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Journal Articles

Abstract 2979: Effects of VEGF inhibition on skin ulcer induced by administration of cytotoxic anticancer drugs

Tatsu Shimoyama, Kiyoshi Ogura, Yuusuke Kanemasa, Shigeo Yamaguti, Eisaku Sasaki, Yasushi Omuro, Takeshi Sawada, Fumiaki Koizumi, Yoshiharu Maeda

Cancer Res (2014) 74 (19_Supplement): 2979.

DOI: https://doi.org/10.1158/1538-7445.AM2014-2979

Published: 01 October 2014

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Journal Articles

Abstract 3061: A novel flow cytometry-based cell capture platform for the detection, capture and molecular characterization of circulating tumor cells

Yasuhiro Koh, Masaru Watanabe, Takeshi Sawada, Hirotsugu Kenmotsu, Masakuni Serizawa, Masayuki Ishige, Kazuo Takeda, Nobuyuki Yamamoto, Toshiaki Takahashi, Fumiaki Koizumi

Cancer Res (2014) 74 (19_Supplement): 3061.

DOI: https://doi.org/10.1158/1538-7445.AM2014-3061

Published: 01 October 2014

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Journal Articles

Abstract 1678: Combined effects of olaparib and cytotoxic agents to triple negative breast cancer cells

Yuki Takashima, Jun Hashimoto, Yuka Kitamura, Shuichi Shimma, Yasuhiro Fujiwara, Fumiaki Koizumi, Kenji Tamura, Akinobu Hamada

Cancer Res (2014) 74 (19_Supplement): 1678.

DOI: https://doi.org/10.1158/1538-7445.AM2014-1678

Published: 01 October 2014

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Journal Articles

Abstract 393: Clinical impact of pentraxin family expression on prognosis in pancreatic carcinoma.

Shunsuke Kondo, Hideki Ueno, Chigusa Morizane, Hiroko Hosoi, Fumiaki Koizumi, Kenji Tamura, Takuji Okusaka

Cancer Res (2013) 73 (8_Supplement): 393.

DOI: https://doi.org/10.1158/1538-7445.AM2013-393

Published: 15 April 2013

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Journal Articles

Abstract 5105: Molecular characterization of captured circulating tumor cells with a novel cell sorting system.

Masaru Watanabe, Takeshi Sawada, Masakuni Serizawa, Yukiko Ito, Yuu Fujimura, Fumiaki Koizumi, Yasuhiro Koh

Cancer Res (2013) 73 (8_Supplement): 5105.

DOI: https://doi.org/10.1158/1538-7445.AM2013-5105

Published: 15 April 2013

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Journal Articles

Abstract 2392: Development of a new assay system for predicting the degree of antibody-dependent cellular cytotoxicity and the clinical outcome in patients receiving trastuzumab.

Kodera Yasuo, Mayu Yunokawa, Kazuhiro Obara, Jun Hashimoto, Kenji Tamura, Yasuhiro Fujiwara, Masato Mitsuhashi, Fumiaki Koizumi

Cancer Res (2013) 73 (8_Supplement): 2392.

DOI: https://doi.org/10.1158/1538-7445.AM2013-2392

Published: 15 April 2013

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Journal Articles

Abstract 1446: Detection of circulating tumor cells for malignant epitherial tumor using a novel cytometry-based system.

Yukiko Ito, Takeshi Sawada, Masaru Watanabe, Yuu Fujimura, Jun Hashimoto, Makoto Kodaira, Mayu Yunokawa, Harukaze Yamamoto, Kan Yonemori, Chikako Shimizu, Kenji Tamura, Yasuhiro Fujiwara, Yasuhiro Koh, Fumiaki Koizumi

Cancer Res (2013) 73 (8_Supplement): 1446.

DOI: https://doi.org/10.1158/1538-7445.AM2013-1446

Published: 15 April 2013

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Journal Articles

Abstract 1445: Clinical feasibility study of a novel cytometry-based-system for the detection of circulating tumor cells of patients with lung cancer.

Takeshi Sawada, Yukiko Ito, Masaru Watanabe, Yuu Fujimura, Shinji Nakamichi, Shintaro Kanda, Hidehito Horinouchi, Yutaka Fujiwara, Hiroshi Nokihara, Noboru Yamamoto, Tomohide Tamura, Yasuhiro Koh, Fumiaki Koizumi

Cancer Res (2013) 73 (8_Supplement): 1445.

DOI: https://doi.org/10.1158/1538-7445.AM2013-1445

Published: 15 April 2013

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Journal Articles

Abstract 5: Frequency of FGFR2 gene amplification in gastric cancer

Kazuko Matsumoto, Tokuzo Arao, Tetsuya Hamaguchi, Yasuhiro Shimada, Ken Kato, Ichiro Oda, Hirokazu Taniguchi, Fumiaki Koizumi, Kazuyoshi Yanagihara, Hiroki Sasaki, Yasuhide Yamada, Kazuto Nishio

Cancer Res (2012) 72 (8_Supplement): 5.

DOI: https://doi.org/10.1158/1538-7445.AM2012-5

Published: 15 April 2012

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Journal Articles

Abstract 1735: Evaluation of a novel flow cytometry-based system for the detection of circulating tumor cells

Masaru Watanabe, Yuri Uehara, Namiko Yamashita, Yuu Fujimura, Kaori Nishio, Junko Suzuki, Fumiaki Koizumi, Yasuhiro Koh

Cancer Res (2012) 72 (8_Supplement): 1735.

DOI: https://doi.org/10.1158/1538-7445.AM2012-1735

Published: 15 April 2012

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Journal Articles

Abstract 2527: Antibody-dependent cellular cytotoxicity of cetuximab against colorectal cancer cells with wild-type and mutant KRAS

Yusuke Nakadate, Yuka Kitamura, Tomohide Tamura, Fumiaki Koizumi

Cancer Res (2012) 72 (8_Supplement): 2527.

DOI: https://doi.org/10.1158/1538-7445.AM2012-2527

Published: 15 April 2012

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Journal Articles

Abstract 3994: Expression levels of EGFR-ligands are up-regulated in EGFR tyrosine kinase inhibitor-resistant cell line

Kazuko Sakai, Tokuzo Arao, Kazuyuki Furuta, Tomoyuki Nagai, Kanae Kudo, Hiroyasu Kaneda, Daisuke Tamura, Keiichi Aomatsu, Yoshihiko Fujita, Kazuko Matsumoto, Fumiaki Koizumi, Kazuto Nishio

Cancer Res (2010) 70 (8_Supplement): 3994.

DOI: https://doi.org/10.1158/1538-7445.AM10-3994

Published: 15 April 2010

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Journal Articles

Abstract 3194: Epidermal growth factor receptor variant type III induces angiopoietin like 4 expression through mitogen activated protein kinase pathway and promotes tumor angiogenesis in malignant glioma

Yasufumi Katanasaka, Fumiaki Koizumi

Cancer Res (2010) 70 (8_Supplement): 3194.

DOI: https://doi.org/10.1158/1538-7445.AM10-3194

Published: 15 April 2010

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Journal Articles

Abstract 1567: The multi-targeted kinase inhibitor Sunitinib blocks VEGF-C signaling pathway and lymphangiogenesis

Kodera Yasuo, Yasufumi Katanasaka, Yuuka Kitamura, Tomohide Tamura, Fumiaki Koizumi

Cancer Res (2010) 70 (8_Supplement): 1567.

DOI: https://doi.org/10.1158/1538-7445.AM10-1567

Published: 15 April 2010

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NARROW

Dysfunction of Poly (ADP-Ribose) Glycohydrolase Induces a Synthetic Lethal Effect in Dual Specificity Phosphatase 22-Deficient Lung Cancer Cells

Abstract 1792: Immune system pathway activation for prediction of the response to neoadjuvant chemotherapy in triple-negative breast cancer

Abstract 500: Prognostic impact of CTC detected using a novel fluidic cell microarray chip CTC detection system in patients with breast cancer

Abstract 4808: Identification of a novel compound, MO2455, that induces poly(ADP-ribose) (PAR) accumulation and inhibits the growth of cancer cells in vitro and in vivo

Abstract 1334: Chemotherapy regulated microRNA-125/HER2 pathway as a novel therapeutic target for trastuzumab-mediated cellular cytotoxicity in small-cell lung cancer

Abstract 1605: Dielectrophoretic microwell array system for detection circulating tumor cells in patients with solid tumors and single cell analysis of detected circulating tumor cells

Abstract 2979: Effects of VEGF inhibition on skin ulcer induced by administration of cytotoxic anticancer drugs

Abstract 3061: A novel flow cytometry-based cell capture platform for the detection, capture and molecular characterization of circulating tumor cells

Abstract 1678: Combined effects of olaparib and cytotoxic agents to triple negative breast cancer cells

Abstract 393: Clinical impact of pentraxin family expression on prognosis in pancreatic carcinoma.

Abstract 5105: Molecular characterization of captured circulating tumor cells with a novel cell sorting system.

Abstract 2392: Development of a new assay system for predicting the degree of antibody-dependent cellular cytotoxicity and the clinical outcome in patients receiving trastuzumab.

Abstract 1446: Detection of circulating tumor cells for malignant epitherial tumor using a novel cytometry-based system.

Abstract 1445: Clinical feasibility study of a novel cytometry-based-system for the detection of circulating tumor cells of patients with lung cancer.

Abstract 5: Frequency of FGFR2 gene amplification in gastric cancer

Abstract 1735: Evaluation of a novel flow cytometry-based system for the detection of circulating tumor cells

Abstract 2527: Antibody-dependent cellular cytotoxicity of cetuximab against colorectal cancer cells with wild-type and mutant KRAS

Abstract 3994: Expression levels of EGFR-ligands are up-regulated in EGFR tyrosine kinase inhibitor-resistant cell line

Abstract 3194: Epidermal growth factor receptor variant type III induces angiopoietin like 4 expression through mitogen activated protein kinase pathway and promotes tumor angiogenesis in malignant glioma

Abstract 1567: The multi-targeted kinase inhibitor Sunitinib blocks VEGF-C signaling pathway and lymphangiogenesis

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