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Frank J. Slack
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Journal Articles

Abstract 5689: miR-21: A therapeutic target that delays severe liver disease and hepatocellular carcinoma under high-fat-diet conditions

Urmila Jagtap, Anan Quan, Yuho Ono, Jonathan Lee, Kylie A. Shen, Sergei Manakov, Gyongyi Szabo, Imad Nasser, Frank J. Slack
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5689.
https://doi.org/10.1158/1538-7445.AM2024-5689
Published: 22 March 2024
View article titled, Abstract 5689: miR-21: A therapeutic target that delays severe liver disease and hepatocellular carcinoma under high-fat-diet conditions
Journal Articles

Abstract 5684: The role of the lncRNA Slamon and Slc25a13 neighbor gene in melanoma aggressiveness

Beatriz C. Tonin, Ana L. Ayub, André H. Lengert, Sang W. Han, Eduardo M. Reis, Frank J. Slack, Miriam G. Jasiulionis
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5684.
https://doi.org/10.1158/1538-7445.AM2024-5684
Published: 22 March 2024
View article titled, Abstract 5684: The role of the lncRNA <em>Slamon</em> and <em>Slc25a13</em> neighbor gene in melanoma aggressiveness
Journal Articles

Abstract 3755: Dlx4os: a lncRNA associated with malignant melanocyte transformation

Ana Luísa P. Ayub, Hatylas Azevedo, Diogo Pessoa, Leinal Sejour, Ioannis Vlachos, Eduardo M. Reis, Frank J. Slack, Miriam G. Jasiulionis
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3755.
https://doi.org/10.1158/1538-7445.AM2023-3755
Published: 04 April 2023
View article titled, Abstract 3755: <em>Dlx4os</em>: a lncRNA associated with malignant melanocyte transformation
Journal Articles

The Emerging Value of Circular Noncoding RNA Research in Cancer Diagnosis and Treatment

Urmila Jagtap, Erik S. Anderson, Frank J. Slack
Journal: Cancer Research
Cancer Res (2023) 83 (6): 809–813.
https://doi.org/10.1158/0008-5472.CAN-22-3014
Published: 15 March 2023
View article titled, The Emerging Value of Circular Noncoding RNA Research in Cancer Diagnosis and Treatment
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Journal Articles

Therapeutic Potential of Chemically Modified, Synthetic, Triplex Peptide Nucleic Acid–Based Oncomir Inhibitors for Cancer Therapy

Karishma Dhuri, Ravinder Reddy Gaddam, Ajit Vikram, Frank J. Slack, Raman Bahal
Journal: Cancer Research
Cancer Res (2021) 81 (22): 5613–5624.
https://doi.org/10.1158/0008-5472.CAN-21-0736
Published: 15 November 2021
View article titled, Therapeutic Potential of Chemically Modified, Synthetic, Triplex Peptide Nucleic Acid–Based Oncomir Inhibitors for Cancer Therapy
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Includes: Supplementary data
Journal Articles

Abstract 2392: Transcriptome analysis from a linear melanoma progression model reveals lncRNAs involved with malignancy, EMT and metastasis

Ana L. Ayub, Diogo Pessoa, Lenial A. Sejour, Ioannis Vlachos, Jérémie Nsengimana, Julia Newton-Bishop, Eduardo M. Reis, Frank J. Slack, Miriam G. Jasiulionis
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2392.
https://doi.org/10.1158/1538-7445.AM2021-2392
Published: 01 July 2021
View article titled, Abstract 2392: Transcriptome analysis from a linear melanoma progression model reveals lncRNAs involved with malignancy, EMT and metastasis
Journal Articles

Abstract 3334: CREB is required for KRAS-driven lung tumorigenesis

Jong woo Lee, Frank J. Slack, Eric J. Nestler, Roy S. Herbst, Jaseok Peter Koo
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3334.
https://doi.org/10.1158/1538-7445.AM2018-3334
Published: 01 July 2018
View article titled, Abstract 3334: CREB is required for <em>KRAS</em>-driven lung tumorigenesis
Journal Articles

OncomiR or Tumor Suppressor? The Duplicity of MicroRNAs in Cancer

Alexander A. Svoronos, Donald M. Engelman, Frank J. Slack
Journal: Cancer Research
Cancer Res (2016) 76 (13): 3666–3670.
https://doi.org/10.1158/0008-5472.CAN-16-0359
Published: 30 June 2016
View article titled, OncomiR or Tumor Suppressor? The Duplicity of MicroRNAs in Cancer
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Journal Articles

miR-34a Silences c-SRC to Attenuate Tumor Growth in Triple-Negative Breast Cancer

Brian D. Adams, Vikram B. Wali, Christopher J. Cheng, Sachi Inukai, Carmen J. Booth, Seema Agarwal, David L. Rimm, Balázs Győrffy, Libero Santarpia, Lajos Pusztai, W. Mark Saltzman, Frank J. Slack
Journal: Cancer Research
Cancer Res (2016) 76 (4): 927–939.
https://doi.org/10.1158/0008-5472.CAN-15-2321
Published: 14 February 2016
View article titled, miR-34a Silences c-SRC to Attenuate Tumor Growth in Triple-Negative Breast Cancer
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Includes: Supplementary data
Journal Articles

The Inescapable Influence of Noncoding RNAs in Cancer

Brian D. Adams, Eleni Anastasiadou, Manel Esteller, Lin He, Frank J. Slack
Journal: Cancer Research
Cancer Res (2015) 75 (24): 5206–5210.
https://doi.org/10.1158/0008-5472.CAN-15-1989
Published: 14 December 2015
View article titled, The Inescapable Influence of Noncoding RNAs in Cancer
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Includes: Supplementary data
Journal Articles

Abstract P4-07-12: Re-introduction of tumor suppressor miR-34a harbors therapeutic efficacy in triple negative breast cancer

Brian D Adams, Lajos Pusztai, David L Rimm, Frank J Slack
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P4-07-12.
https://doi.org/10.1158/1538-7445.SABCS14-P4-07-12
Published: 01 May 2015
View article titled, Abstract P4-07-12: Re-introduction of tumor suppressor miR-34a harbors therapeutic efficacy in triple negative breast cancer
Journal Articles

Abstract 974: Targeting the tumor microenvironment with antimiRs that exploit oncomiR addiction in lymphoma

Christopher J. Cheng, Don M. Engelman, Mark Saltzman, Frank J. Slack
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 974.
https://doi.org/10.1158/1538-7445.AM2014-974
Published: 01 October 2014
View article titled, Abstract 974: Targeting the tumor microenvironment with antimiRs that exploit oncomiR addiction in lymphoma
Journal Articles

miRNA-34 Prevents Cancer Initiation and Progression in a Therapeutically Resistant K-ras and p53-Induced Mouse Model of Lung Adenocarcinoma

Andrea L. Kasinski, Frank J. Slack
Journal: Cancer Research
Cancer Res (2012) 72 (21): 5576–5587.
https://doi.org/10.1158/0008-5472.CAN-12-2001
Published: 31 October 2012
View article titled, miRNA-34 Prevents Cancer Initiation and Progression in a Therapeutically Resistant K-ras and p53-Induced Mouse Model of Lung Adenocarcinoma
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Includes: Supplementary data
Journal Articles

Abstract 2950: miR-34 prevents in vivo lung tumor initiation and progression in the therapeutically resistant Kras;p53 mouse model

Andrea L. Kasinski, Frank J. Slack
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2950.
https://doi.org/10.1158/1538-7445.AM2012-2950
Published: 15 April 2012
View article titled, Abstract 2950: miR-34 prevents <em>in vivo</em> lung tumor initiation and progression in the therapeutically resistant Kras;p53 mouse model
Journal Articles

A KRAS-Variant in Ovarian Cancer Acts as a Genetic Marker of Cancer Risk

Elena Ratner, Lingeng Lu, Marta Boeke, Rachel Barnett, Sunitha Nallur, Lena J. Chin, Cory Pelletier, Rachel Blitzblau, Renata Tassi, Trupti Paranjape, Pei Hui, Andrew K. Godwin, Herbert Yu, Harvey Risch, Thomas Rutherford, Peter Schwartz, Alessandro Santin, Ellen Matloff, Daniel Zelterman, Frank J. Slack, Joanne B. Weidhaas
Journal: Cancer Research
Cancer Res (2010) 70 (16): 6509–6515.
https://doi.org/10.1158/0008-5472.CAN-10-0689
Published: 14 August 2010
View article titled, A <em>KRAS</em>-Variant in Ovarian Cancer Acts as a Genetic Marker of Cancer Risk
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Includes: Supplementary data
Journal Articles

A SNP in a let-7 microRNA Complementary Site in the KRAS 3′ Untranslated Region Increases Non–Small Cell Lung Cancer Risk

Lena J. Chin, Elena Ratner, Shuguang Leng, Rihong Zhai, Sunitha Nallur, Imran Babar, Roman-Ulrich Muller, Eva Straka, Li Su, Elizabeth A. Burki, Richard E. Crowell, Rajeshvari Patel, Trupti Kulkarni, Robert Homer, Daniel Zelterman, Kenneth K. Kidd, Yong Zhu, David C. Christiani, Steven A. Belinsky, Frank J. Slack, Joanne B. Weidhaas
Journal: Cancer Research
Cancer Res (2008) 68 (20): 8535–8540.
https://doi.org/10.1158/0008-5472.CAN-08-2129
Published: 15 October 2008
View article titled, A SNP in a <em>let-7</em> microRNA Complementary Site in the <em>KRAS</em> 3′ Untranslated Region Increases Non–Small Cell Lung Cancer Risk
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Includes: Supplementary data
Journal Articles

MicroRNAs as Potential Agents to Alter Resistance to Cytotoxic Anticancer Therapy

Joanne B. Weidhaas, Imran Babar, Sunitha M. Nallur, Phong Trang, Sarah Roush, Michelle Boehm, Erin Gillespie, Frank J. Slack
Journal: Cancer Research
Cancer Res (2007) 67 (23): 11111–11116.
https://doi.org/10.1158/0008-5472.CAN-07-2858
Published: 03 December 2007
View article titled, MicroRNAs as Potential Agents to Alter Resistance to Cytotoxic Anticancer Therapy
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Includes: Supplementary data
Journal Articles

The let-7 MicroRNA Represses Cell Proliferation Pathways in Human Cells

Charles D. Johnson, Aurora Esquela-Kerscher, Giovanni Stefani, Mike Byrom, Kevin Kelnar, Dmitriy Ovcharenko, Mike Wilson, Xiaowei Wang, Jeffrey Shelton, Jaclyn Shingara, Lena Chin, David Brown, Frank J. Slack
Journal: Cancer Research
Cancer Res (2007) 67 (16): 7713–7722.
https://doi.org/10.1158/0008-5472.CAN-07-1083
Published: 15 August 2007
View article titled, The <em>let-7</em> MicroRNA Represses Cell Proliferation Pathways in Human Cells
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Includes: Supplementary data