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Journal Articles

Abstract 6057: Association of liver cancer and chronic liver disease with urinary glyphosate and its metabolites in Thailand

Daxesh P. Patel, Benjarath Pupacdi, Siritida Rabibhadana, Leila Toulabi, Majda Haznadar, Bhavik Dalal, Mohammed Khan, Joshua Stone, Vajarabhongsa Bhudhisawasdi, Nirush Lertprasertsuke, Anon Chotirosniramit, Chawalit Pairojkul, Chirayu U. Auewarakul, Thaniya Sricharunrat, Kannika Phornphutkul, Suleeporn Sangrajrang, Anuradha Budhu, Chulabhorn Mahidol, Xin W. Wang, Frank J. Gonzalez, Mathuros Ruchirawat, Christopher A. Loffredo, Curtis C. Harris, TIGER-LC Consortium
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6057.
https://doi.org/10.1158/1538-7445.AM2023-6057
Published: 04 April 2023
View articletitled, Abstract 6057: Association of liver cancer and chronic liver disease with urinary glyphosate and its metabolites in Thailand
Journal Articles

Abstract 5824: Fully-humanized, bioengineered miR-1291 modulates key nutrient transport and metabolism to control tumor metabolism

Mei-Juan Tu, Frank J. Gonzalez, Ai-Ming Yu
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5824.
https://doi.org/10.1158/1538-7445.AM2022-5824
Published: 15 June 2022
View articletitled, Abstract 5824: Fully-humanized, bioengineered miR-1291 modulates key nutrient transport and metabolism to control tumor metabolism
Journal Articles

Mutant Idh2 Cooperates with a NUP98-HOXD13 Fusion to Induce Early Immature Thymocyte Precursor ALL

Liat Goldberg, Vijay Negi, Yang Jo Chung, Masahiro Onozawa, Yuelin J. Zhu, Robert L. Walker, Rachel Pierce, Daxesh P. Patel, Kristopher W. Krausz, Frank J. Gonzalez, Margaret A. Goodell, Benjamin A.T. Rodriguez, Paul S. Meltzer, Peter D. Aplan
Journal: Cancer Research
Cancer Res (2021) 81 (19): 5033–5046.
https://doi.org/10.1158/0008-5472.CAN-21-1027
Published: 01 October 2021
View articletitled, Mutant Idh2 Cooperates with a NUP98-HOXD13 Fusion to Induce Early Immature Thymocyte Precursor ALL
Open the PDF for Mutant Idh2 Cooperates with a NUP98-HOXD13 Fusion to Induce Early Immature Thymocyte Precursor ALL in another window
Includes: Supplementary data
Journal Articles

Abstract 4366: Characterization of diacetylspermine as a metabolic urinary biomarker in breast cancer using patient-derived xenografts

Thomas J. Velenosi, Kristopher W. Krausz, Frank J. Gonzalez
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4366.
https://doi.org/10.1158/1538-7445.AM2019-4366
Published: 01 July 2019
View articletitled, Abstract 4366: Characterization of diacetylspermine as a metabolic urinary biomarker in breast cancer using patient-derived xenografts
Journal Articles

Retraction: Disruption of the NAD(P)H:Quinone Oxidoreductase 1 (NQO1) Gene in Mice Causes Myelogenous Hyperplasia

Delwin J. Long, II, Amos Gaikwad, Asha Multani, Sen Pathak, Charles A. Montgomery, Frank J. Gonzalez, Anil K. Jaiswal
Journal: Cancer Research
Cancer Res (2018) 78 (22): 6526.
https://doi.org/10.1158/0008-5472.CAN-18-2455
Published: 15 November 2018
View articletitled, Retraction: Disruption of the NAD(P)H:Quinone Oxidoreductase 1 (NQO1) Gene in Mice Causes Myelogenous Hyperplasia
Open the PDF for Retraction: Disruption of the NAD(P)H:Quinone Oxidoreductase 1 (NQO1) Gene in Mice Causes Myelogenous Hyperplasia in another window
Journal Articles

Abstract 2700: Intestinal Vitamin D receptor deficiency increases susceptibility for the DSS-induced colon disease

Jung-Hwan Kim, Satoshi Yamaori, Frank J. Gonzalez
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2700.
https://doi.org/10.1158/1538-7445.AM2017-2700
Published: 01 July 2017
View articletitled, Abstract 2700: Intestinal Vitamin D receptor deficiency increases susceptibility for the DSS-induced colon disease
Journal Articles

Abstract 2500: Urinary metabolites are diagnostic biomarkers of liver cancer

Majda Haznadar, Kristopher W. Krausz, Christopher M. Diehl, Elise D. Bowman, Anuradha S. Budhu, Jittiporn Chaisaingmongkol, Siritida Rabibhadana, Marshonna Forgues, Takahiro Oike, Mathuros Ruchirawat, Frank J. Gonzalez, Xin W. Wang, Curtis C. Harris
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2500.
https://doi.org/10.1158/1538-7445.AM2017-2500
Published: 01 July 2017
View articletitled, Abstract 2500: Urinary metabolites are diagnostic biomarkers of liver cancer
Journal Articles

Abstract 1850: Transcription factor E2F3 up-regulates the expression of Gadd45b gene in the mouse liver

Jung-Hwan Kim, Frank J. Gonzalez
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1850.
https://doi.org/10.1158/1538-7445.AM2016-1850
Published: 15 July 2016
View articletitled, Abstract 1850: Transcription factor E2F3 up-regulates the expression of Gadd45b gene in the mouse liver
Journal Articles

Abstract 4320: Circulating vitamin D2 and D3 levels and single nucleotide polymorphism associations with lung cancer status: A case-control study

Majda Haznadar, Kristopher W. Krausz, Ezra Margono, Elise D. Bowman, Brid M. Ryan, Frank J. Gonzalez, Curtis C. Harris
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4320.
https://doi.org/10.1158/1538-7445.AM2016-4320
Published: 15 July 2016
View articletitled, Abstract 4320: Circulating vitamin D2 and D3 levels and single nucleotide polymorphism associations with lung cancer status: A case-control study
Journal Articles

Mass Spectrometry–Based Metabolomics Identifies Longitudinal Urinary Metabolite Profiles Predictive of Radiation-Induced Cancer

John A. Cook, Gadisetti V.R. Chandramouli, Miriam R. Anver, Anastasia L. Sowers, Angela Thetford, Kristopher W. Krausz, Frank J. Gonzalez, James B. Mitchell, Andrew D. Patterson
Journal: Cancer Research
Cancer Res (2016) 76 (6): 1569–1577.
https://doi.org/10.1158/0008-5472.CAN-15-2416
Published: 14 March 2016
View articletitled, Mass Spectrometry–Based Metabolomics Identifies Longitudinal Urinary Metabolite Profiles Predictive of Radiation-Induced Cancer
Open the PDF for Mass Spectrometry–Based Metabolomics Identifies Longitudinal Urinary Metabolite Profiles Predictive of Radiation-Induced Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 935: Lung cancer metabolomics identifies metabolites as robust risk biomarkers

Majda Haznadar, Qiuyin Cai, Kristopher W. Krausz, Elise D. Bowman, William J. Blot, Frank J. Gonzalez, Curtis C. Harris
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 935.
https://doi.org/10.1158/1538-7445.AM2015-935
Published: 01 August 2015
View articletitled, Abstract 935: Lung cancer metabolomics identifies metabolites as robust risk biomarkers
Journal Articles

Abstract 23: Nuclear receptor PPARα activation triggers hepatic cell death in Ikkβ-deficient mice

Jung-Hwan Kim, Taehyeong Kim, Aijuan Qu, Frank J. Gonzalez
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 23.
https://doi.org/10.1158/1538-7445.AM2015-23
Published: 01 August 2015
View articletitled, Abstract 23: Nuclear receptor PPARα activation triggers hepatic cell death in Ikkβ-deficient mice
Journal Articles

Abstract 492: Hepatic oxidative stress activates the Gadd45b gene via degradation of the transcriptional repressor STAT3

Jung-Hwan Kim, Aijuan Qu, Janardan K. Reddy, Bin Gao, Frank J. Gonzalez
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 492.
https://doi.org/10.1158/1538-7445.AM2014-492
Published: 01 October 2014
View articletitled, Abstract 492: Hepatic oxidative stress activates the Gadd45b gene via degradation of the transcriptional repressor STAT3
Journal Articles

Noninvasive Urinary Metabolomic Profiling Identifies Diagnostic and Prognostic Markers in Lung Cancer

Ewy A. Mathé, Andrew D. Patterson, Majda Haznadar, Soumen K. Manna, Kristopher W. Krausz, Elise D. Bowman, Peter G. Shields, Jeffrey R. Idle, Philip B. Smith, Katsuhiro Anami, Dickran G. Kazandjian, Emmanuel Hatzakis, Frank J. Gonzalez, Curtis C. Harris
Journal: Cancer Research
Cancer Res (2014) 74 (12): 3259–3270.
https://doi.org/10.1158/0008-5472.CAN-14-0109
Published: 12 June 2014
View articletitled, Noninvasive Urinary Metabolomic Profiling Identifies Diagnostic and Prognostic Markers in Lung Cancer
Open the PDF for Noninvasive Urinary Metabolomic Profiling Identifies Diagnostic and Prognostic Markers in Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 1295: Inhibition of clonogenicity and xenograft tumor growth by activation and/or over-expression of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ).

Pei-Li Yao, Michael G. Borland, Prasad Krishnan, Bokai Zhu, Frank J. Gonzalez, Jeffrey M. Peters
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1295.
https://doi.org/10.1158/1538-7445.AM2013-1295
Published: 15 April 2013
View articletitled, Abstract 1295: Inhibition of clonogenicity and xenograft tumor growth by activation and/or over-expression of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ).
Journal Articles

Abstract 1901: Untargeted metabolomic profiling identifies diagnostic and prognostic biomarkers of lung cancer.

Majda Haznadar, Ewy Mathe, Andrew D. Patterson, Soumen K. Manna, Kristopher W. Krausz, Elise D. Bowman, Jeffrey R. Idle, Dickran G. Kazandjian, Frank J. Gonzalez, Curtis C. Harris
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1901.
https://doi.org/10.1158/1538-7445.AM2013-1901
Published: 15 April 2013
View articletitled, Abstract 1901: Untargeted metabolomic profiling identifies diagnostic and prognostic biomarkers of lung cancer.
Journal Articles

Hypoxia-Inducible Factor-2α Activation Promotes Colorectal Cancer Progression by Dysregulating Iron Homeostasis

Xiang Xue, Matthew Taylor, Erik Anderson, Cathy Hao, Aijuan Qu, Joel K. Greenson, Ellen M. Zimmermann, Frank J. Gonzalez, Yatrik M. Shah
Journal: Cancer Research
Cancer Res (2012) 72 (9): 2285–2293.
https://doi.org/10.1158/0008-5472.CAN-11-3836
Published: 30 April 2012
View articletitled, Hypoxia-Inducible Factor-2α Activation Promotes Colorectal Cancer Progression by Dysregulating Iron Homeostasis
Open the PDF for Hypoxia-Inducible Factor-2α Activation Promotes Colorectal Cancer Progression by Dysregulating Iron Homeostasis in another window
Includes: Supplementary data
Journal Articles

Abstract 2172: Anti-oncogenic role of peroxisome proliferator-activated receptor-α/β (PPARδ/α) involves inhibition of mitosis and regulation of Hras1-induced senescence

Bokai Zhu, Combiz Khozoie, Christina H. Ferry, Lauren M. Markell, Moses T. Bility, Nicholas Blazanin, Adam B. Glick, Frank J. Gonzalez
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2172.
https://doi.org/10.1158/1538-7445.AM2012-2172
Published: 15 April 2012
View articletitled, Abstract 2172: Anti-oncogenic role of peroxisome proliferator-activated receptor-α/β (PPARδ/α) involves inhibition of mitosis and regulation of Hras1-induced senescence
Journal Articles

Aberrant Lipid Metabolism in Hepatocellular Carcinoma Revealed by Plasma Metabolomics and Lipid Profiling

Andrew D. Patterson, Olivier Maurhofer, Diren Beyoğlu, Christian Lanz, Kristopher W. Krausz, Thomas Pabst, Frank J. Gonzalez, Jean-François Dufour, Jeffrey R. Idle
Journal: Cancer Research
Cancer Res (2011) 71 (21): 6590–6600.
https://doi.org/10.1158/0008-5472.CAN-11-0885
Published: 30 October 2011
View articletitled, Aberrant Lipid Metabolism in Hepatocellular Carcinoma Revealed by Plasma Metabolomics and Lipid Profiling
Open the PDF for Aberrant Lipid Metabolism in Hepatocellular Carcinoma Revealed by Plasma Metabolomics and Lipid Profiling in another window
Includes: Supplementary data
Journal Articles

Abstract 1227: Anti-oncogenic role of Peroxisome proliferator-activated receptor- β/Δ (Pparβ/Δ) involves regulation of viral Hras1 (v-Hras1)-induced senescence and endoplasmic reticulum (ER) stress in mouse primary keratinocytes

Bokai Zhu, Combiz Khozoie, Moses Bility, Nicholas Blazanin, Adam B. Glick, Frank J. Gonzalez, Jeffrey M. Peters
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1227.
https://doi.org/10.1158/1538-7445.AM2011-1227
Published: 15 April 2011
View articletitled, Abstract 1227: Anti-oncogenic role of Peroxisome proliferator-activated receptor- β/Δ (Pparβ/Δ) involves regulation of viral Hras1 (v-Hras1)-induced senescence and endoplasmic reticulum (ER) stress in mouse primary keratinocytes