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Franco Zunino
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Journal Articles

Abstract 3289: Microenvironment modulation and enhancement of cytotoxic therapy by the heparanase inhibitor Roneparstat against human B-non Hodgkin lymphomas

Massimo Di Nicola, Franco Zunino, Anna Rossini, Giusi Ruggiero, Micheleandrea De Cesare, Denis Cominetti, Monica Tortoreto, Cinzia Lanzi, Giuliana Cassinelli, Roberta Zappasodi, Claudio Tripodo, Nadia Zaffaroni
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3289.
https://doi.org/10.1158/1538-7445.AM2016-3289
Published: 15 July 2016
View article titled, Abstract 3289: Microenvironment modulation and enhancement of cytotoxic therapy by the heparanase inhibitor Roneparstat against human B-non Hodgkin lymphomas
Journal Articles

Abstract 4719: The HDAC inhibitor ITF2357 blocks c-Myc expression via microRNA modulation and cap-dependent translation inhibition in human Burkitt's lymphoma

Roberta Zappasodi, Alessandra Cavane', Marilena V. Iorio, Monica Tortoreto, Giusi Ruggiero, Michele Magni, Elda Tagliabue, Franco Zunino, Carlo M. Croce, Alessandro M. Gianni, Massimo Di Nicola
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4719.
https://doi.org/10.1158/1538-7445.AM2012-4719
Published: 15 April 2012
View article titled, Abstract 4719: The HDAC inhibitor ITF2357 blocks c-Myc expression via microRNA modulation and cap-dependent translation inhibition in human Burkitt's lymphoma
Journal Articles

Abstract 2623: ST3595, a new histone deacetylase (HDAC) inhibitor endowed with a peculiar mechanism of action

Claudio Pisano, Loredana Vesci, Ferdinando M. Milazzo, Mario B. Guglielmi, Marcella Barbarino, Rosanna Foderà, Valentina Zuco, Franco Zunino
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2623.
https://doi.org/10.1158/1538-7445.AM2011-2623
Published: 15 April 2011
View article titled, Abstract 2623: ST3595, a new histone deacetylase (HDAC) inhibitor endowed with a peculiar mechanism of action
Journal Articles

Abstract 566: Interaction of acetyl-L-carnitine with platinum compounds: A possible role of protein acetylation in modulation of antitumor activity

Claudio Pisano, Loredana Vesci, Ferdinando Maria Milazzo, Mario Bernandino Guglielmi, Rosanna Foderà, Marcella Barbarino, Giovanna Petrangolini, Monica Tortoreto, Paolo Carminati, Claudio Cavazza, Franco Zunino
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 566.
https://doi.org/10.1158/1538-7445.AM10-566
Published: 15 April 2010
View article titled, Abstract 566: Interaction of acetyl-L-carnitine with platinum compounds: A possible role of protein acetylation in modulation of antitumor activity
Journal Articles

Abstract #257: Targeting heparanase as a therapy for multiple myeloma

Yang Yang, Joseph Ritchie, Li Nan, Annamaria Naggi, Giangiacomo Torri, Benito Casu, Claudio Pisano, Paolo Carminati, Sergio Penco, Monica Tortoreto, Franco Zunino, Israel Vlodavsky, Ralph Sanderson
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 257.
Published: 01 May 2009
View article titled, Abstract #257: Targeting heparanase as a therapy for multiple myeloma
Journal Articles

Abstract #1811: Antitumor activity of SST0001 a new heparin derivative targeting heparanase

Claudio Pisano, Benito Casu, Annamaria Naggi, Giangiacomo Torri, Sergio Penco, Walter Cabri, Monica Tortoreto, Franco Zunino, Loredana Vesci, Rosanna Foderà, Ferdinando Milazzo, Marcella Barbarino, Federica Bucci, Concetta Aulicino, Nicola Gargano, Elisa Beghetto, Adriano Angelucci, Mauro Bologna, Paolo Carminati
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1811.
Published: 01 May 2009
View article titled, Abstract #1811: Antitumor activity of SST0001 a new heparin derivative targeting heparanase
Journal Articles

Hypersensitivity of human squamous cell carcinoma xenografts to the novel camptothecin analog ST1968

Claudio Pisano, Valentina Zuco, Michelandrea De Cesare, Valentina Benedetti, Giovanni Luca Beretta, Loredana Vesci, Rosanna Fodera, Federica Bucci, Concetta Aulicino, Paolo Carminati, Franco Zunino
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 765.
Published: 01 May 2008
View article titled, Hypersensitivity of human squamous cell carcinoma xenografts to the novel camptothecin analog ST1968
Journal Articles

Identification and pharmacological characterization of ST1968, a new camptothecin derivative

Claudio Pisano, Loredana Vesci, Rosanna Fodera, Fabiana Fosca Ferrara, Mario Guglielmi, Federica Bucci, Concetta Aulicino, Angelo Marconi, Patrizia Tobia, Paolo Carminati, Giovanni Luca Beretta, Michelandrea De Cesare, Franco Zunino
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 776.
Published: 01 May 2007
View article titled, Identification and pharmacological characterization of ST1968, a new camptothecin derivative
Journal Articles

Antitumor activity of ST1968, a novel topoisomerase I inhibitor

Claudio Pisano, Loredana Vesci, Rosanna Fodera, Fabiana Fosca Ferrara, Sergio Penco, Paolo Carminati, Lucio Merlini, Michelandrea De Cesare, Franco Zunino
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 778.
Published: 01 May 2007
View article titled, Antitumor activity of ST1968, a novel topoisomerase I inhibitor
Journal Articles

Biological Properties of IDN5174, a New Synthetic Camptothecin with the Open Lactone Ring

Giovanni L. Beretta, Giovanna Petrangolini, Michelandrea De Cesare, Graziella Pratesi, Paola Perego, Stella Tinelli, Monica Tortoreto, Massimo Zucchetti, Roberta Frapolli, Ezia Bello, Carla Manzotti, Gabriele Fontana, Ezio Bombardelli, Arturo Battaglia, Cristian Samorì, Franco Zunino
Journal: Cancer Research
Cancer Res (2006) 66 (22): 10976–10982.
https://doi.org/10.1158/0008-5472.CAN-06-2158
Published: 15 November 2006
View article titled, Biological Properties of IDN5174, a New Synthetic Camptothecin with the Open Lactone Ring
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Journal Articles

A novel inhibitor of vacuolar H+-ATPase, NIK-12192, potentiates the antitumor effect of topotecan in BCRP-expressing tumor systems.

Rosanna Supino, Giovanna Petrangolini, Anna C. Croce, Laura Dal Bo, Monica Tortoreto, Graziella Pratesi, Paola Misiano, Carlo Farina, Franco Zunino
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1273.
Published: 15 April 2006
View article titled, A novel inhibitor of vacuolar H<sup>+</sup>-ATPase, NIK-12192, potentiates the antitumor effect of topotecan in BCRP-expressing tumor systems.
Journal Articles

Antitumor activity of a new synthetic camptothecin with the open lacton ring.

Graziella Pratesi, Giovanni L. Beretta, Michelandrea De Cesare, Giovanna Petrangolini, Maria Stella Tinelli, Massimo Zucchetti, Roberta Frapolli, Carla Manzotti, Ezio Bombardelli, Franco Zunino
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1301.
Published: 15 April 2006
View article titled, Antitumor activity of a new synthetic camptothecin with the open lacton ring.
Journal Articles

Modulation of Survival Signaling Pathways and Persistence of the Genotoxic Stress as a Basis for the Synergistic Interaction between the Atypical Retinoid ST1926 and the Epidermal Growth Factor Receptor Inhibitor ZD1839

Chiara Zanchi, Valentina Zuco, Cinzia Lanzi, Rosanna Supino, Franco Zunino
Journal: Cancer Research
Cancer Res (2005) 65 (6): 2364–2372.
https://doi.org/10.1158/0008-5472.CAN-04-2495
Published: 21 March 2005
View article titled, Modulation of Survival Signaling Pathways and Persistence of the Genotoxic Stress as a Basis for the Synergistic Interaction between the Atypical Retinoid ST1926 and the Epidermal Growth Factor Receptor Inhibitor ZD1839
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Journal Articles

Potent Antitumor Activity and Improved Pharmacological Profile of ST1481, a Novel 7-substituted Camptothecin

Michelandrea De Cesare, Graziella Pratesi, Paola Perego, Nives Carenini, Stella Tinelli, Lucio Merlini, Sergio Penco, Claudio Pisano, Federica Bucci, Loredana Vesci, Silvia Pace, Francesca Capocasa, Paolo Carminati, Franco Zunino
Journal: Cancer Research
Cancer Res (2001) 61 (19): 7189–7195.
Published: 01 October 2001
View article titled, Potent Antitumor Activity and Improved Pharmacological Profile of ST1481, a Novel 7-substituted Camptothecin
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Journal Articles

A Novel 7-modified Camptothecin Analog Overcomes Breast Cancer Resistance Protein-associated Resistance in a Mitoxantrone-selected Colon Carcinoma Cell Line

Paola Perego, Michelandrea De Cesare, Paola De Isabella, Nives Carenini, Gino Beggiolin, Gabriella Pezzoni, Manlio Palumbo, Loris Tartaglia, Graziella Pratesi, Claudio Pisano, Paolo Carminati, George L. Scheffer, Franco Zunino
Journal: Cancer Research
Cancer Res (2001) 61 (16): 6034–6037.
Published: 01 August 2001
View article titled, A Novel 7-modified Camptothecin Analog Overcomes Breast Cancer Resistance Protein-associated Resistance in a Mitoxantrone-selected Colon Carcinoma Cell Line
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Journal Articles

A Novel Taxane with Improved Tolerability and Therapeutic Activity in a Panel of Human Tumor Xenografts

Donatella Polizzi, Graziella Pratesi, Monica Tortoreto, Rosanna Supino, Antonella Riva, Ezio Bombardelli, Franco Zunino
Journal: Cancer Research
Cancer Res (1999) 59 (5): 1036–1040.
Published: 01 March 1999
View article titled, A Novel Taxane with Improved Tolerability and Therapeutic Activity in a Panel of Human Tumor Xenografts
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Journal Articles

Human DNA Topoisomerase IIα-dependent DNA Cleavage and Yeast Cell Killing by Anthracycline Analogues

Monica Binaschi, Rosalba Farinosi, Caroline A. Austin, L. Mark Fisher, Franco Zunino, Giovanni Capranico
Journal: Cancer Research
Cancer Res (1998) 58 (9): 1886–1892.
Published: 01 May 1998
View article titled, Human DNA Topoisomerase IIα-dependent DNA Cleavage and Yeast Cell Killing by Anthracycline Analogues
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Journal Articles

Irreversible and Reversible Topoisomerase II DNA Cleavage Stimulated by Clerocidin: Sequence Specificity and Structural Drug Determinants

Monica Binaschi, Giuseppe Zagotto, Manlio Palumbo, Franco Zunino, Rosalba Farinosi, Giovanni Capranico
Journal: Cancer Research
Cancer Res (1997) 57 (9): 1710–1716.
Published: 01 May 1997
View article titled, Irreversible and Reversible Topoisomerase II DNA Cleavage Stimulated by Clerocidin: Sequence Specificity and Structural Drug Determinants
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Journal Articles

Drug-specific Sites of Topoisomerase II DNA Cleavage in Drosophila Chromatin: Heterogeneous Localization and Reversibility

Maria E. Borgnetto, Franco Zunino, Stella Tinelli, Emmanuel Käs, Giovanni Capranico
Journal: Cancer Research
Cancer Res (1996) 56 (8): 1855–1862.
Published: 01 April 1996
View article titled, Drug-specific Sites of Topoisomerase II DNA Cleavage in <em>Drosophila</em> Chromatin: Heterogeneous Localization and Reversibility
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Journal Articles

Association between Cisplatin Resistance and Mutation of p53 Gene and Reduced Bax Expression in Ovarian Carcinoma Cell Systems

Paola Perego, Monica Giarola, Sabina C. Righetti, Rosanna Supino, Claudia Caserini, Domenico Delia, Marco A. Pierotti, Toshiyuki Miyashita, John C. Reed, Franco Zunino
Journal: Cancer Research
Cancer Res (1996) 56 (3): 556–562.
Published: 01 February 1996
View article titled, Association between Cisplatin Resistance and Mutation of <em>p53</em> Gene and Reduced Bax Expression in Ovarian Carcinoma Cell Systems
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