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Journal Articles

Abstract 2677: Multi-omics profiling identifies two epithelioid sarcoma molecular subtypes with distinct signaling and immune characteristics

Carine Ngo, Leo Colmet-Daage, Julien Vibert, Clémence Henon, Riwan Brillet, Jia Xiang Jin, Daniel Pissaloux, Clémence Astier, Jean-Yves Blay, Axel Le Cesne, Charles Honore, Matthieu Faron, Thomas Grünewald, Franck Bourdeaut, Franck Tirode, Sophie Postel-Vinay

Cancer Res (2025) 85 (8_Supplement_1): 2677.

https://doi.org/10.1158/1538-7445.AM2025-2677

Published: 21 April 2025

View articletitled, Abstract 2677: Multi-omics profiling identifies two epithelioid sarcoma molecular subtypes with distinct signaling and immune characteristics

Journal Articles

Abstract 6071: Whole-exome RNA sequencing of metastatic synovial sarcomas reveals heterogeneous transcriptomic profile and targetable co-alterations: Cohort study from the French Sarcoma Group

Helene Vanacker, Mehdi Brahmi, Yannick Le Meitour, Julien Bollard, Valery Attignon, Alexandra Meurgey, Myriam Jean-Denis, Laurie Tonon, Shibani Pokras, Erika Klohe, Michael Nathenson, Kristin Blouch, Ioanna Eleftheriadou, Jean-Yves Blay, Franck Tirode, Armelle Dufresne

Cancer Res (2023) 83 (7_Supplement): 6071.

https://doi.org/10.1158/1538-7445.AM2023-6071

Published: 04 April 2023

View articletitled, Abstract 6071: Whole-exome RNA sequencing of metastatic synovial sarcomas reveals heterogeneous transcriptomic profile and targetable co-alterations: Cohort study from the French Sarcoma Group

Journal Articles

Abstract 3525: VGLL2-NCOA2 leverages developmental programs for pediatric sarcomagenesis

Sarah Watson, Collette A. LaVigne, Lin Xu, Didier Surdez, Joanna Cyrta, Delia Calderon, Matthew V. Cannon, Matthew R. Kent, Katherine M. Silvius, Jack P. Kucinski, Emma N. Harrison, Whitney Murchison, Dinesh Rakheja, Franck Tirode, Olivier Delattre, James F. Amatruda, Genevieve C. Kendall

Cancer Res (2023) 83 (7_Supplement): 3525.

https://doi.org/10.1158/1538-7445.AM2023-3525

Published: 04 April 2023

View articletitled, Abstract 3525: VGLL2-NCOA2 leverages developmental programs for pediatric sarcomagenesis

Journal Articles

Abstract 872: Genetic models reveal that the novel VGLL2-NCOA2 fusion oncogene leverages embryonic programs for sarcomagenesis

Genevieve C. Kendall, Sarah Watson, Lin Xu, Collette LaVigne, Whitney Murchison, Dinesh Rakheja, Franck Tirode, Olivier Delattre, James Amatruda

Cancer Res (2019) 79 (13_Supplement): 872.

https://doi.org/10.1158/1538-7445.AM2019-872

Published: 01 July 2019

View articletitled, Abstract 872: Genetic models reveal that the novel VGLL2-NCOA2 fusion oncogene leverages embryonic programs for sarcomagenesis

Journal Articles

Abstract A13: Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility

Mitchell J. Machiela, Thomas G.P. Grünewald, Didier Surdez, Stephanie Reynaud, Olivier Mirabeau, Eric Karlins, Rebeca Alba Rubio, Sakina Zaidi, Sandrine Grossetete-Lalami, Stelly Ballet, Eve Lapouble, Valérie Laurence, Jean Michon, Gaelle Pierron, Heinrich Kovar, Nathalie Gaspar, Udo Kontny, Anna González-Neira, Piero Picci, Javier Alonso, Ana Patino-Garcia, Nadège Corradini, Neal D. Freedman, Nathaniel Rothman, Casey L. Dagnall, Laurie Burdett, Kristine Jones, Michelle Manning, Kathleen Wyatt, Weiyin Zhou, Meredith Yeager, David G. Cox, Robert N. Hoover, Javed Khan, Gregory T. Armstrong, Wendy M. Leisenring, Smita Bhatia, Leslie L. Robison, Uta Dirksen, Markus Metzler, Wolfgang Hartmann, Konstantin Strauch, Thomas Kirchner, Andreas E. Kulozik, Lindsay M. Morton, Lisa Mirabello, Margaret A. Tucker, Franck Tirode, Stephen Chanock, Olivier Delattre

Cancer Res (2018) 78 (19_Supplement): A13.

https://doi.org/10.1158/1538-7445.PEDCA17-A13

Published: 01 October 2018

View articletitled, Abstract A13: Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility

Journal Articles

Abstract 2970: Multiple new susceptibility loci identified in genome-wide association study of Ewing sarcoma

Mitchell J. Machiela, Thomas G. Grünewald, Didier Surdez, Stephanie Reynaud, Olivier Mirabeau, Eric Karlins, Rebeca Alba Rubio, Sakina Zaidi, Sandrine Grossetete-Lalami, Stelly Ballet, Eve Lapouble, Valérie Laurence, Jean Michon, Gaelle Pierron, Heinrich Kovar, Nathalie Gaspar, Udo Kontny, Anna González-Neira, Piero Picci, Javier Alonso, Ana Patino-Garcia, Nadège Corradini, Neal D. Freedman, Nathaniel Rothman, Casey L. Dagnall, Laurie Burdette, Kristine Jones, Michelle Manning, Kathleen Wyatt, Weiyin Zhou, Meredith Yeager, David G. Cox, Robert N. Hoover, Javed Khan, Gregory T. Armstrong, Wendy M. Leisenring, Smita Bhatia, Leslie L. Robison, Uta Dirksen, Markus Metzler, Wolfgang Hartmann, Konstantin Strauch, Thomas Kirchner, Andreas E. Kulozik, Lindsay M. Morton, Lisa Mirabello, Margaret A. Tucker, Franck Tirode, Stephen J. Chanock, Olivier Delattre

Cancer Res (2018) 78 (13_Supplement): 2970.

https://doi.org/10.1158/1538-7445.AM2018-2970

Published: 01 July 2018

View articletitled, Abstract 2970: Multiple new susceptibility loci identified in genome-wide association study of Ewing sarcoma

Journal Articles

Abstract NG03: Zebrafish models of PAX3-FOXO1 pathogenesis reveal novel targets in human rhabdomyosarcoma

Genevieve Kendall, Sarah Watson, Lin Xu, Franck Tirode, Olivier Delattre, James Amatruda

Cancer Res (2016) 76 (14_Supplement): NG03.

https://doi.org/10.1158/1538-7445.AM2016-NG03

Published: 15 July 2016

View articletitled, Abstract NG03: Zebrafish models of PAX3-FOXO1 pathogenesis reveal novel targets in human rhabdomyosarcoma

Journal Articles

Abstract 973: A long noncoding RNA-regulating enhancer links Ewing sarcoma susceptibility to stress response

Dave NT Aryee, Eleni Tomazou, Maximilian Kauer, Thomas Grünewald, Franck Tirode, Olivier Delattre, Heinrich Kovar

Cancer Res (2016) 76 (14_Supplement): 973.

https://doi.org/10.1158/1538-7445.AM2016-973

Published: 15 July 2016

View articletitled, Abstract 973: A long noncoding RNA-regulating enhancer links Ewing sarcoma susceptibility to stress response

Journal Articles

Abstract 4190: Expression of a human CIC-DUX4 fusion is sufficient to induce malignant small round blue cell tumors in zebrafish: a new model of CIC-DUX4 sarcoma for translational research

Sarah Watson, Genevieve Kendall, Olivier Delattre, Franck Tirode, James F. Amatruda

Cancer Res (2016) 76 (14_Supplement): 4190.

https://doi.org/10.1158/1538-7445.AM2016-4190

Published: 15 July 2016

View articletitled, Abstract 4190: Expression of a human CIC-DUX4 fusion is sufficient to induce malignant small round blue cell tumors in zebrafish: a new model of CIC-DUX4 sarcoma for translational research

Journal Articles

Abstract 4472: Targeting the oncogenic transcription factor EWS-Fli1 by BET bromodomain inhibition in Ewing sarcoma

Camille JACQUES, François LAMOUREUX, Marc BAUD’HUIN, Lidia RODRIGUEZ-CALLEJA, Thibaut QUILLARD, Pierre PERROT, Franck TIRODE, Françoise REDINI, James E. BRADNER, Dominique HEYMANN, Benjamin ORY

Cancer Res (2016) 76 (14_Supplement): 4472.

https://doi.org/10.1158/1538-7445.AM2016-4472

Published: 15 July 2016

View articletitled, Abstract 4472: Targeting the oncogenic transcription factor EWS-Fli1 by BET bromodomain inhibition in Ewing sarcoma

Journal Articles

Abstract PR13: DNA methylation mapping and computational modeling in a large Ewing sarcoma cohort identifies principles of tumor heterogeneity and their impact on clinical phenotypes

Cancer Res (2016) 76 (5_Supplement): PR13.

https://doi.org/10.1158/1538-7445.PEDCA15-PR13

Published: 04 April 2016

View articletitled, Abstract PR13: DNA methylation mapping and computational modeling in a large Ewing sarcoma cohort identifies principles of tumor heterogeneity and their impact on clinical phenotypes

Journal Articles

Abstract B71: A systems biology approach to study Ewing's sarcoma

Didier Surdez, Gautier Stoll, Franck Tirode, Karine Laud, Andrei Zinovyev, Emmanuel Barillot, Olivier Delattre

Cancer Res (2009) 69 (23_Supplement): B71.

https://doi.org/10.1158/0008-5472.FBCR09-B71

Published: 28 October 2014

View articletitled, Abstract B71: A systems biology approach to study Ewing's sarcoma

Journal Articles

Abstract A20: Protein kinase C beta II is crucial for Ewing sarcoma cell survival

Dider Surdez, Magdalena Benetkiewicz, Virginie Perrin, Olivier Delattre, Franck Tirode

Cancer Res (2009) 69 (23_Supplement): A20.

https://doi.org/10.1158/0008-5472.FBCR09-A20

Published: 28 October 2014

View articletitled, Abstract A20: Protein kinase C beta II is crucial for Ewing sarcoma cell survival

Journal Articles

Abstract A10: Functional characterization of Ewing's sarcoma susceptibility loci

Thomas Grunewald, Marie-Ming Aynaud, Franck Tirode, Eleni Tomazou, Didier Surdez, Thomas Rio Frio, Virginie Bernard, Virginie Raynal, Carlo Lucchesi, Gaelle Pierron, Pascale Gilardi-Hebenstreit, Patrick Charnay, Heinrich Kovar, Olivier Delattre

Cancer Res (2014) 74 (20_Supplement): A10.

https://doi.org/10.1158/1538-7445.PEDCAN-A10

Published: 09 October 2014

View articletitled, Abstract A10: Functional characterization of Ewing's sarcoma susceptibility loci

Journal Articles

Abstract A59: Deciphering the role(s) of the FET family of proteins in the Ewing sarcoma model: Is EWS-FLI-1 crashing the party?

Sarah Cohen-Gogo, Franck Tirode, Olivier Delattre

Cancer Res (2014) 74 (20_Supplement): A59.

https://doi.org/10.1158/1538-7445.PEDCAN-A59

Published: 09 October 2014

View articletitled, Abstract A59: Deciphering the role(s) of the FET family of proteins in the Ewing sarcoma model: Is EWS-FLI-1 crashing the party?

Journal Articles

Abstract 3989: High throughput screening highlights NFkB signaling in Ewing sarcoma

Didier Surdez, Gautier Stoll, Franck Tirode, Karine Laud, Emmanuel Barillot, Olivier Delattre

Cancer Res (2014) 74 (19_Supplement): 3989.

https://doi.org/10.1158/1538-7445.AM2014-3989

Published: 01 October 2014

View articletitled, Abstract 3989: High throughput screening highlights NFkB signaling in Ewing sarcoma

Journal Articles

Targeting the EWSR1-FLI1 Oncogene-Induced Protein Kinase PKC-β Abolishes Ewing Sarcoma Growth

Didier Surdez, Magdalena Benetkiewicz, Virginie Perrin, Zhi-Yan Han, Gaëlle Pierron, Stelly Ballet, François Lamoureux, Françoise Rédini, Anne-Valérie Decouvelaere, Estelle Daudigeos-Dubus, Birgit Geoerger, Gonzague de Pinieux, Olivier Delattre, Franck Tirode

Cancer Res (2012) 72 (17): 4494–4503.

https://doi.org/10.1158/0008-5472.CAN-12-0371

Published: 30 August 2012

View articletitled, Targeting the EWSR1-FLI1 Oncogene-Induced Protein Kinase PKC-β Abolishes Ewing Sarcoma Growth

Includes: Supplementary data

Journal Articles

Zoledronic Acid as a New Adjuvant Therapeutic Strategy for Ewing's Sarcoma Patients

Guillaume A. Odri, Sophie Dumoucel, Gaëlle Picarda, Séverine Battaglia, François Lamoureux, Nadège Corradini, Julie Rousseau, Franck Tirode, Karine Laud, Olivier Delattre, François Gouin, Dominique Heymann, Françoise Redini

Cancer Res (2010) 70 (19): 7610–7619.

https://doi.org/10.1158/0008-5472.CAN-09-4272

Published: 29 September 2010

View articletitled, Zoledronic Acid as a New Adjuvant Therapeutic Strategy for Ewing's Sarcoma Patients

Includes: Supplementary data

Journal Articles

Strong Smooth Muscle Differentiation Is Dependent on Myocardin Gene Amplification in Most Human Retroperitoneal Leiomyosarcomas

Gaëlle Pérot, Josette Derré, Jean-Michel Coindre, Franck Tirode, Carlo Lucchesi, Odette Mariani, Laure Gibault, Louis Guillou, Philippe Terrier, Alain Aurias

Cancer Res (2009) 69 (6): 2269–2278.

https://doi.org/10.1158/0008-5472.CAN-08-1443

Published: 17 March 2009

View articletitled, Strong Smooth Muscle Differentiation Is Dependent on Myocardin Gene Amplification in Most Human Retroperitoneal Leiomyosarcomas

Includes: Supplementary data

Journal Articles

A mesechymal stem cell origin of Ewing tumors

Franck Tirode, Karine Laud-Duval, Alexandre Prieur, Bruno Delorme, Pierre Charbord, Olivier Delattre

Cancer Res (2007) 67 (9_Supplement): 1293.

Published: 01 May 2007

View articletitled, A mesechymal stem cell origin of Ewing tumors

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Abstract 2677: Multi-omics profiling identifies two epithelioid sarcoma molecular subtypes with distinct signaling and immune characteristics

Abstract 6071: Whole-exome RNA sequencing of metastatic synovial sarcomas reveals heterogeneous transcriptomic profile and targetable co-alterations: Cohort study from the French Sarcoma Group

Abstract 3525: VGLL2-NCOA2 leverages developmental programs for pediatric sarcomagenesis

Abstract 872: Genetic models reveal that the novel VGLL2-NCOA2 fusion oncogene leverages embryonic programs for sarcomagenesis

Abstract A13: Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility

Abstract 2970: Multiple new susceptibility loci identified in genome-wide association study of Ewing sarcoma

Abstract NG03: Zebrafish models of PAX3-FOXO1 pathogenesis reveal novel targets in human rhabdomyosarcoma

Abstract 973: A long noncoding RNA-regulating enhancer links Ewing sarcoma susceptibility to stress response

Abstract 4190: Expression of a human CIC-DUX4 fusion is sufficient to induce malignant small round blue cell tumors in zebrafish: a new model of CIC-DUX4 sarcoma for translational research

Abstract 4472: Targeting the oncogenic transcription factor EWS-Fli1 by BET bromodomain inhibition in Ewing sarcoma

Abstract PR13: DNA methylation mapping and computational modeling in a large Ewing sarcoma cohort identifies principles of tumor heterogeneity and their impact on clinical phenotypes

Abstract B71: A systems biology approach to study Ewing's sarcoma

Abstract A20: Protein kinase C beta II is crucial for Ewing sarcoma cell survival

Abstract A10: Functional characterization of Ewing's sarcoma susceptibility loci

Abstract A59: Deciphering the role(s) of the FET family of proteins in the Ewing sarcoma model: Is EWS-FLI-1 crashing the party?

Abstract 3989: High throughput screening highlights NFkB signaling in Ewing sarcoma

Targeting the EWSR1-FLI1 Oncogene-Induced Protein Kinase PKC-β Abolishes Ewing Sarcoma Growth

Zoledronic Acid as a New Adjuvant Therapeutic Strategy for Ewing's Sarcoma Patients

Strong Smooth Muscle Differentiation Is Dependent on Myocardin Gene Amplification in Most Human Retroperitoneal Leiomyosarcomas

A mesechymal stem cell origin of Ewing tumors

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