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Francis Y. F. Lee
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Journal Articles

Abstract 1145: AGX323 - A SAM-competitive, orally available inhibitor of protein arginine methyltransferase 5 (PRMT5) with potent cellular antiproliferative and in vivo antitumor activity against selected solid cancer types

Francis Y. F. Lee, Wen-Lian Wu, Zhiqiang Yang, John Tan
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1145.
https://doi.org/10.1158/1538-7445.AM2021-1145
Published: 01 July 2021
View article titled, Abstract 1145: AGX323 - A SAM-competitive, orally available inhibitor of protein arginine methyltransferase 5 (PRMT5) with potent cellular antiproliferative and <em>in vivo</em> antitumor activity against selected solid cancer types
Journal Articles

Apoptotic and Cytostatic Farnesyltransferase Inhibitors Have Distinct Pharmacology and Efficacy Profiles in Tumor Models

Veeraswamy Manne, Francis Y. F. Lee, David K. Bol, Johnni Gullo-Brown, Craig R. Fairchild, Louis J. Lombardo, Richard A. Smykla, Gregory D. Vite, Mei-Li D. Wen, Chiang Yu, Tai Wai Wong, John T. Hunt
Journal: Cancer Research
Cancer Res (2004) 64 (11): 3974–3980.
https://doi.org/10.1158/0008-5472.CAN-03-3849
Published: 01 June 2004
View article titled, Apoptotic and Cytostatic Farnesyltransferase Inhibitors Have Distinct Pharmacology and Efficacy Profiles in Tumor Models
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Journal Articles

Preclinical Antitumor Activity of BMS-214662, a Highly Apoptotic and Novel Farnesyltransferase Inhibitor

William C. Rose, Francis Y. F. Lee, Craig R. Fairchild, Mark Lynch, Thomas Monticello, Robert A. Kramer, Veeraswamy Manne
Journal: Cancer Research
Cancer Res (2001) 61 (20): 7507–7517.
Published: 01 October 2001
View article titled, Preclinical Antitumor Activity of BMS-214662, a Highly Apoptotic and Novel Farnesyltransferase Inhibitor
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Journal Articles

Modulation of the Cell Cycle-dependent Cytotoxicity of Adriamycin and 4-Hydroperoxycyclophosphamide by Novobiocin, an Inhibitor of Mammalian Topoisomerase II

Francis Y. F. Lee, Deborah J. Flannery, Dietmar W. Siemann
Journal: Cancer Research
Cancer Res (1992) 52 (13): 3515–3520.
Published: 01 July 1992
View article titled, Modulation of the Cell Cycle-dependent Cytotoxicity of Adriamycin and 4-Hydroperoxycyclophosphamide by Novobiocin, an Inhibitor of Mammalian Topoisomerase II
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Journal Articles

Comparison of Glutathione Levels in Rodent and Human Tumor Cells Grown in Vitro and in Vivo

M. Joan Allalunis-Turner, Francis Y. F. Lee, Dietmar W. Siemann
Journal: Cancer Research
Cancer Res (1988) 48 (13): 3657–3660.
Published: 01 July 1988
View article titled, Comparison of Glutathione Levels in Rodent and Human Tumor Cells Grown <em>in Vitro</em> and <em>in Vivo</em>
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Journal Articles

Glutathione Contents in Human and Rodent Tumor Cells in Various Phases of the Cell Cycle

Francis Y. F. Lee, Dietmar W. Siemann, M. Joan Allalunis-Turner, Peter C. Keng
Journal: Cancer Research
Cancer Res (1988) 48 (13): 3661–3665.
Published: 01 July 1988
View article titled, Glutathione Contents in Human and Rodent Tumor Cells in Various Phases of the Cell Cycle
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