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François Bertucci
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Journal Articles

Abstract PO2-03-06: Pathological complete response with chemotherapy and immune checkpoint inhibition in triple negative inflammatory breast cancer (TN-IBC)

Free
Filipa Lynce, Samuel Niman, Anthony Gonçalves, Megumi Kai, Sean Ryan, Elizabeth Troll, Rachel Layman, Antonio Giordano, Azadeh Nasrazadani, Faina Nakhlis, Jennifer Bellon, Laura Warren, Caroline Block, Susan Schumer, Anthony Lucci, Savitri Krishnamurthy, Florence Lerebours, Florence Dalenc, Christelle Levy, Thierry Petit, Marianne Leheurteur, Thomas Bachelot, Olivier Trédan, Sylvain Ladoire, Leonor Lopez Almeida, Christophe Zemmour, Sara Tolaney, Vicente Valero, François BERTUCCI, Meredith Regan, Wendy Woodward
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO2-03-06.
https://doi.org/10.1158/1538-7445.SABCS23-PO2-03-06
Published: 02 May 2024
View articletitled, Abstract PO2-03-06: Pathological complete response with chemotherapy and immune checkpoint inhibition in triple negative inflammatory breast cancer (TN-IBC)
Journal Articles

Abstract PO4-05-06: Hormone receptor-positive HER2-low metastatic breast cancer (mBC): evolution of HER2 status after CDK4/6 inhibitor treatment

Free
Alexandre de Nonneville, Pascal Finetti, Laurys Boudin, Lucas Usclade, Lenaïg Mescam, Emeline Durieux, Agathe Boucraut, Frederic Viret, Emilie Mamessier, Anthony Gonçalves, François Bertucci
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO4-05-06.
https://doi.org/10.1158/1538-7445.SABCS23-PO4-05-06
Published: 02 May 2024
View articletitled, Abstract PO4-05-06: Hormone receptor-positive HER2-low metastatic breast cancer (mBC): evolution of HER2 status after CDK4/6 inhibitor treatment
Journal Articles

Abstract PO3-02-07: HER2-low status in inflammatory breast cancer (IBC) is associated with hormone receptors positivity but not with pathological response to neoadjuvant chemotherapy or overall survival

Free
Alexandre de Nonneville, Pascal FINETTI, Laurys Boudin, Lucas Usclade, Patrice Viens, Frederic VIRET, Emilie Mamessier, Anthony Gonçalves, François BERTUCCI
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO3-02-07.
https://doi.org/10.1158/1538-7445.SABCS23-PO3-02-07
Published: 02 May 2024
View articletitled, Abstract PO3-02-07: HER2-low status in inflammatory breast cancer (IBC) is associated with hormone receptors positivity but not with pathological response to neoadjuvant chemotherapy or overall survival
Journal Articles

CD25high Effector Regulatory T Cells Hamper Responses to PD-1 Blockade in Triple-Negative Breast Cancer

Open Access
Stéphane Fattori, Aude Le Roy, Jemila Houacine, Lucie Robert, Riad Abes, Laurent Gorvel, Samuel Granjeaud, Marie-Sarah Rouvière, Amira Ben Amara, Nicolas Boucherit, Carole Tarpin, Jihane Pakradouni, Emmanuelle Charafe-Jauffret, Gilles Houvenaeghel, Eric Lambaudie, François Bertucci, Philippe Rochigneux, Anthony Gonçalves, Arnaud Foussat, Anne-Sophie Chrétien, Daniel Olive
Journal: Cancer Research
Cancer Res (2023) 83 (18): 3026–3044.
https://doi.org/10.1158/0008-5472.CAN-23-0613
Published: 15 September 2023
View articletitled, CD25high Effector Regulatory T Cells Hamper Responses to PD-1 Blockade in Triple-Negative Breast Cancer
Open the PDF for CD25high Effector Regulatory T Cells Hamper Responses to PD-1 Blockade in Triple-Negative Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 3239: Selective depletion of regulatory T cells by ALD2510, a novel IL-2-sparing anti-CD25 antibody, synergizes with PD-1 blockade in breast and gynecologic cancers

Free
Stéphane FATTORI, Aude Le Roy, Jemila Houacine, Lucie Robert, Riad Abes, Laurent Gorvel, Samuel Granjeaud, Marie-Sarah Rouvière, Amira Ben Amara, Nicolas Boucherit, Carole Tarpin, Jihane Pakradouni, Emmanuelle Charafe-Jauffret, Julien Barrou, Gilles Houvenaeghel, Eric Lambaudie, François Bertucci, Philippe Rochigneux, Anthony Gonçalves, Arnaud Foussat, Anne-Sophie Chrétien, Daniel Olive
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3239.
https://doi.org/10.1158/1538-7445.AM2023-3239
Published: 04 April 2023
View articletitled, Abstract 3239: Selective depletion of regulatory T cells by ALD2510, a novel IL-2-sparing anti-CD25 antibody, synergizes with PD-1 blockade in breast and gynecologic cancers
Journal Articles

Abstract P6-10-15: Targeting MARCKS in inflammatory breast cancer increased paclitaxel sensitivity

Free
Maroua Manai, Ines Bini, Pascal Finetti, Haifa Bichiou, Carolina Reduzzi, Naziha Ben Hamida, Marc Lopez, Khaled Rahal, Karima Mrad, Mohamed Manai, Massimo Cristofanilli, Hamouda Boussen, Raoudha Doghri, Maher Kharrat, François Bertucci
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P6-10-15.
https://doi.org/10.1158/1538-7445.SABCS22-P6-10-15
Published: 01 March 2023
View articletitled, Abstract P6-10-15: Targeting MARCKS in inflammatory breast cancer increased paclitaxel sensitivity
Journal Articles

Abstract P3-05-23: Pathological complete response rate and disease-free survival after neoadjuvant chemotherapy in patients with HER2-low and HER2-0 breast cancers

Free
Alexandre de Nonneville, Gilles HOUVENAEGHEL, Monique Cohen, Laura SABIANI, Marie BANNIER, Frederic VIRET, Anthony Gonçalves, François BERTUCCI
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P3-05-23.
https://doi.org/10.1158/1538-7445.SABCS22-P3-05-23
Published: 01 March 2023
View articletitled, Abstract P3-05-23: Pathological complete response rate and disease-free survival after neoadjuvant chemotherapy in patients with HER2-low and HER2-0 breast cancers
Journal Articles

Abstract P6-01-47: Stromal tumor infiltrating lymphocytes and pathological complete response in patients with inflammatory breast cancer treated with neoadjuvant chemotherapy

Free
Maxim De Schepper, Ha-Linh Nguyen, François Richard, Florence Lerebours, Roman Vion, Florian Clatot, Anca Berghian, Marion Maetens, Sophia Leduc, Edoardo Isnaldi, Chiara Molinelli, Matteo Lambertini, Frederica Grillo, Gabriele Zoppoli, Luc Dirix, Hilde Wuyts, Kevin Punie, Hans Wildiers, Chantal Remmerie, Ann Smeets, Ines Nevelsteen, Patrick Neven, Anne Salomon, Denis Larsimont, Caroline Duhem, Patrice Viens, François BERTUCCI, Elia Biganzoli, Peter Vermeulen, Giuseppe Floris, Christine Desmedt
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P6-01-47.
https://doi.org/10.1158/1538-7445.SABCS22-P6-01-47
Published: 01 March 2023
View articletitled, Abstract P6-01-47: Stromal tumor infiltrating lymphocytes and pathological complete response in patients with inflammatory breast cancer treated with neoadjuvant chemotherapy
Journal Articles

Abstract 2578: High regulatory T cells infiltrate within tertiary lymphoid structure restricts response to immune checkpoint blockers in sarcomas

Free
Florent Peyraud, Jean-Philippe Guegan, Christophe Rey, Marina Pulido, Emmanuelle Bompas, Sophie Piperno-Neumann, Christine Chevreau, Nicolas Penel, François Bertucci, Maud Toulmonde, Carine Bellera, Catherine Sautès-Fridman, Antoine Bougoüin, Coralie Cantarel, Michèle Kind, Mariella Spalato-Ceruso, Bérengère Dadone-Montaudie, Jean-Yves Blay, Wolf Herman Fridman, François Le Loarer, Alban Bessede, Antoine Italiano
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2578.
https://doi.org/10.1158/1538-7445.AM2022-2578
Published: 15 June 2022
View articletitled, Abstract 2578: High regulatory T cells infiltrate within tertiary lymphoid structure restricts response to immune checkpoint blockers in sarcomas
Journal Articles

Abstract 2737: A mechanistic model for prediction of metastatic relapse in early-stage breast cancer using routine clinical features

Free
Célestin Bigarré, Pascal Finetti, François Bertucci, Xavier Muracciole, Sébastien Benzekry
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2737.
https://doi.org/10.1158/1538-7445.AM2022-2737
Published: 15 June 2022
View articletitled, Abstract 2737: A mechanistic model for prediction of metastatic relapse in early-stage breast cancer using routine clinical features
Journal Articles

Abstract P1-04-07: Xiap expression is associated with infiltration of cd163+ tumor-associated macrophages in the tumor micro-environment of inflammatory breast cancer

Free
Christophe Van Berckelaer, Steven Van Laere, Joseph Gerardts, Luc Dirix, Michael Morse, Mark Kockx, François Bertucci, Peter Van Dam, Gayathri R Devi
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P1-04-07.
https://doi.org/10.1158/1538-7445.SABCS21-P1-04-07
Published: 15 February 2022
View articletitled, Abstract P1-04-07: Xiap expression is associated with infiltration of cd163+ tumor-associated macrophages in the tumor micro-environment of inflammatory breast cancer
Journal Articles

Abstract PD10-08: Remodeling the inflammatory breast cancer tumor microenvironment to enhance immunotherapy: Novel therapeutic development

Free
Xiaoping Wang, Takashi Semba, Ganiraju C. Manyam, Jing Wang, Shan Shao, Francois Bertucci, Pascal Finetti, Savitri Krishnamurthy, Lan ThiHanh Phi, Troy Pearson, Jared K. Burks, Evan N. Cohen, James M. Reuben, Fei Yang, Hu Min, Nicholas Navin, Toshiaki Iwase, Yichao Shen, Xiang Zhang, Debu Tripathy, Naoto T. Ueno
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): PD10-08.
https://doi.org/10.1158/1538-7445.SABCS21-PD10-08
Published: 15 February 2022
View articletitled, Abstract PD10-08: Remodeling the inflammatory breast cancer tumor microenvironment to enhance immunotherapy: Novel therapeutic development
Journal Articles

Abstract 2290: The serine-threonine kinase Mink1 as a potential therapeutic target in triple negative breast cancer

Free
Avais Daulat, Monica Silveira Wagner, Malgorzata Kowalczewska, Pascal Finetti, Rémy Castellano, Stéphane Audebert, François Bertucci, Luc Camoin, Jean-Paul Borg
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2290.
https://doi.org/10.1158/1538-7445.AM2021-2290
Published: 01 July 2021
View articletitled, Abstract 2290: The serine-threonine kinase Mink1 as a potential therapeutic target in triple negative breast cancer
Journal Articles

Abstract P3-03-03: Inflammatory breast cancer exhibits amplification and transcriptional activation of MYC in conjunction with NOTCH and TGFβ signaling

Free
Charlotte Rypens, François Bertucci, Patrice Viens, John WM Martens, Marcel Smid, Carolien Schröder, Naoto T Ueno, Massimo Cristofanilli, Piet Dirix, Peter Vermeulen, Luc Dirix, Steven Van Laere
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P3-03-03.
https://doi.org/10.1158/1538-7445.SABCS19-P3-03-03
Published: 15 February 2020
View articletitled, Abstract P3-03-03: Inflammatory breast cancer exhibits amplification and transcriptional activation of MYC in conjunction with NOTCH and TGFβ signaling
Journal Articles

Abstract 4622: Identification of p62/SQSTM1 as a component of non-canonical WNT VANGL2-JNK signaling in breast cancer

Free
Jean-Paul Borg, Puvirajesinghe Tania, François Bertucci, Daniel Birnbaum, Ashish Jain, Terje Johansen, Pierluigi Scerbo, Laurent Kodjabachian
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4622.
https://doi.org/10.1158/1538-7445.AM2016-4622
Published: 15 July 2016
View articletitled, Abstract 4622: Identification of p62/SQSTM1 as a component of non-canonical WNT VANGL2-JNK signaling in breast cancer
Journal Articles

Abstract 4790: Breast cancer stem cells: The next step in the area of personalized medicine

Free
Emmanuelle Charafe-Jauffret, Christophe Ginestier, Olivier Cabaud, Julien Wicinski, Arnaud Guille, Severine Garnier, Max Chaffanet, Anthony Goncalves, Francois Bertucci, Daniel Birnbaum
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4790.
https://doi.org/10.1158/1538-7445.AM2016-4790
Published: 15 July 2016
View articletitled, Abstract 4790: Breast cancer stem cells: The next step in the area of personalized medicine
Journal Articles

Abstract 2666: The miR-424/503 cluster is a breast cancer tumor suppressor with a role in chemoresistance

Free
David Llobet Navas, Francois Bertucci, Ruth Rodriguez-Barrueco, Jose Silva
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2666.
https://doi.org/10.1158/1538-7445.AM2016-2666
Published: 15 July 2016
View articletitled, Abstract 2666: The miR-424/503 cluster is a breast cancer tumor suppressor with a role in chemoresistance
Journal Articles

Autocrine Secretion of Progastrin Promotes the Survival and Self-Renewal of Colon Cancer Stem–like Cells

Free
Julie Giraud, Laura M. Failla, Jean-Marc Pascussi, Ebba L. Lagerqvist, Jérémy Ollier, Pascal Finetti, François Bertucci, Chu Ya, Imène Gasmi, Jean-François Bourgaux, Michel Prudhomme, Thibault Mazard, Imade Ait-Arsa, Leila Houhou, Daniel Birnbaum, André Pélegrin, Charles Vincent, James G. Ryall, Dominique Joubert, Julie Pannequin, Frédéric Hollande
Journal: Cancer Research
Cancer Res (2016) 76 (12): 3618–3628.
https://doi.org/10.1158/0008-5472.CAN-15-1497
Published: 14 June 2016
View articletitled, Autocrine Secretion of Progastrin Promotes the Survival and Self-Renewal of Colon Cancer Stem–like Cells
Open the PDF for Autocrine Secretion of Progastrin Promotes the Survival and Self-Renewal of Colon Cancer Stem–like Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 381: Circulating tumor cells (CTC) but not circulating endothelial cells (CEC) are independent prognostic factors in neoadjuvant chemotherapy combined with bevacizumab in HER2 negative inflammatory breast cancer (IBC) in multicentre phase II trial BEVERLY1

Free
Jean-Yves Pierga, Francois-Clement Bidard, Aurelie Autret, Fabrice Andre, Thierry Petit, Florence Dalenc, Christel Levy, William Jacot, Jacques Bonneterre, Jean-Marc Ferrero, Pierre Kerbrat, Jerome Lemonnier, Francois Bertucci, Patrice Viens
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 381.
https://doi.org/10.1158/1538-7445.AM2015-381
Published: 01 August 2015
View articletitled, Abstract 381: Circulating tumor cells (CTC) but not circulating endothelial cells (CEC) are independent prognostic factors in neoadjuvant chemotherapy combined with bevacizumab in HER2 negative inflammatory breast cancer (IBC) in multicentre phase II trial BEVERLY1
Journal Articles

Abstract P2-05-06: Identification of specific gene signatures and alternative splice variants using exon array in Inflammatory breast Cancer

Free
Florence Lerebours, Sophie Vacher, Marie Le Cann, Sophie Rondeau, David Gentien, Steven Van Laere, François Bertucci, Pierre de la Grange, Ivan Bieche
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P2-05-06.
https://doi.org/10.1158/1538-7445.SABCS14-P2-05-06
Published: 01 May 2015
View articletitled, Abstract P2-05-06: Identification of specific gene signatures and alternative splice variants using exon array in Inflammatory breast Cancer