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Journal Articles

Abstract P28: Comprehensive Molecular Phenotyping of ARID1A-deficient Gastric Cancer Reveals Pervasive Epigenomic Reprogramming and Therapeutic Opportunities

Chang Xu, Kie Kyon Huang, Jia Hao Law, Joy Shijia Chua, Taotao Sheng, Natasha M. Flores, Melissa Pool Pizzi, Atsushi Okabe, Angie Lay Keng Tan, Feng Zhu, Vikrant Kumar, Xiaoyin Lu, Ana Morales Benitez, Benedict Shi Xiang Lian, Haoran Ma, Shamaine Wei Ting Ho, Kalpana Ramnarayanan, Chukwuemeka George Anene-Nzelu, Milad Razavi-Mohseni, Siti Aishah Binte Abdul Ghani, Su Ting Tay, Xuewen Ong, Ming Hui Lee, Yu Amanda Guo, Hassan Ashktorab, Duane Smoot, Shang Li, Anders Jacobsen Skanderup, Michael A. Beer, Roger Sik Yin Foo, Joel Shi Hao Wong, Kaushal Sanghvi, Wei Peng Yong, Raghav Sundar, Atsushi Kaneda, Shyam Prabhakar, Pawel Karol Mazur, Jaffer A. Ajani, Khay Guan Yeoh, Jimmy Bok-Yan So, Patrick Tan, Singapore Gastric Cancer Consortium
Journal: Cancer Research
Cancer Res (2024) 84 (8_Supplement): P28.
https://doi.org/10.1158/1538-7445.FCS2023-P28
Published: 15 April 2024
View article titled, Abstract P28: Comprehensive Molecular Phenotyping of <em>ARID1A</em>-deficient Gastric Cancer Reveals Pervasive Epigenomic Reprogramming and Therapeutic Opportunities
Journal Articles

Abstract 2798: Oral fungal infection tweaks the innate immune tumor microenvironment promoting

Xin Li, Na-Young Song, Amit Kumar Singh, Jonathan Badger, Chengfei Jiang, Feng Zhu, Debra Tross, Yongmei Zhao, Bao Tran, Yinling Hu
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2798.
https://doi.org/10.1158/1538-7445.AM2024-2798
Published: 22 March 2024
View article titled, Abstract 2798: Oral fungal infection tweaks the innate immune tumor microenvironment promoting
Journal Articles

Abstract 761: Integrated environmental, lifestyle, and epigenetic risk prediction of primary gastric cancer

Genki Usui, Keisuke Matsusaka, Kie K. Huang, Feng Zhu, Tomohiro Shinozaki, Masaki Fukuyo, Bahityar Rahmutulla, Norikazu Yogi, Tomoka Okada, Motoaki Seki, Eiji Sakai, Kazutoshi Fujibayashi, Stephen K. Tsao, Christopher Khor, Tiing L. Ang, Hiroyuki Abe, Hisahiro Matsubara, Masashi Fukayama, Toshiaki Gunji, Nobuyuki Matsuhashi, Teppei Morikawa, Tetsuo Ushiku, Khay G. Yeoh, Patrick Tan, Atsushi Kaneda
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 761.
https://doi.org/10.1158/1538-7445.AM2023-761
Published: 04 April 2023
View article titled, Abstract 761: Integrated environmental, lifestyle, and epigenetic risk prediction of primary gastric cancer
Journal Articles

Abstract 926: IIKKa deletion amplifies renal transitional epithelial stem cells and initiates lethal invasive papillary urothelial cell carcinoma development

Xin Li, Feng Zhu, Chengfei Jiang, Yongmei Zhao, Bao Tran, Donna Butcher, Xiaolin Wu, Tross Debra, Yinling Hu
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 926.
https://doi.org/10.1158/1538-7445.AM2022-926
Published: 15 June 2022
View article titled, Abstract 926: IIKKa deletion amplifies renal transitional epithelial stem cells and initiates lethal invasive papillary urothelial cell carcinoma development
Journal Articles

Abstract 3044: C. albicans infection mediates upper gastrointestinal tract malignancy independently of Il17a in an APECED-like mouse model

Feng Zhu, Quynh T. Phan, Elise M. Ferre, Jami Willette-Brown, Rosalba Salcedo, Tsai-Wei Shen, Yu Fan, Yongmei Zhao, Monika Mehta, Daoud Meerzaman, Bao Tran, Giorgio Trinchieri, Michail S. Lionakis, Scott G. Filler, Yinling Hu
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3044.
https://doi.org/10.1158/1538-7445.AM2022-3044
Published: 15 June 2022
View article titled, Abstract 3044: <em>C. albicans</em> infection mediates upper gastrointestinal tract malignancy independently of Il17a in an APECED-like mouse model
Journal Articles

Abstract PR10: Candida albicans infection mediates gastrointestinal track malignancy independently of Il17a in an APECED mouse model

Feng Zhu, Jami Willette-Brown, Trang Phan, Yongmei Zhao, Bao Tran, Scott G. Filler, Mihalis S. Lionakis, Yinling Hu
Journal: Cancer Research
Cancer Res (2020) 80 (8_Supplement): PR10.
https://doi.org/10.1158/1538-7445.MVC2020-PR10
Published: 15 April 2020
View article titled, Abstract PR10: <em>Candida albicans</em> infection mediates gastrointestinal track malignancy independently of Il17a in an APECED mouse model
Journal Articles

Abstract B17: IKKα/STAT3 antagonistic signaling regulates fungi-bacteria endosymbiosis-associated carcinogenesis

Na-Young Song, Xin Li, Jonathan H. Badger, Jami Willette Brown, Xhonghe Sun, Gongping Shi, Feng Zhu, Chengfei Jiang, Colum O'hUigin, Xiaolin Wu, Giorgio Trinchieri, Yinling Hu
Journal: Cancer Research
Cancer Res (2020) 80 (8_Supplement): B17.
https://doi.org/10.1158/1538-7445.MVC2020-B17
Published: 15 April 2020
View article titled, Abstract B17: IKKα/STAT3 antagonistic signaling regulates fungi-bacteria endosymbiosis-associated carcinogenesis
Journal Articles

Clonal Mutations Activate the NF-κB Pathway to Promote Recurrence of Nasopharyngeal Carcinoma

Rui You, You-Ping Liu, De-Chen Lin, Qing Li, Tao Yu, Xiong Zou, Mei Lin, Xiao-Long Zhang, Gui-Ping He, Qi Yang, Yi-Nuan Zhang, Yu-Long Xie, Rou Jiang, Chen-Yan Wu, Chao Zhang, Cheng Cui, Jing-Qi Wang, Yue Wang, Ai-Hua Zhuang, Gui-Fang Guo, Yi-Jun Hua, Rui Sun, Jing-Ping Yun, Zhi-Xiang Zuo, Ze-Xian Liu, Xiao-Feng Zhu, Tie-Bang Kang, Chao-Nan Qian, Hai-Qiang Mai, Ying Sun, Mu-Sheng Zeng, Lin Feng, Yi-Xin Zeng, Ming-Yuan Chen
Journal: Cancer Research
Cancer Res (2019) 79 (23): 5930–5943.
https://doi.org/10.1158/0008-5472.CAN-18-3845
Published: 02 December 2019
View article titled, Clonal Mutations Activate the NF-κB Pathway to Promote Recurrence of Nasopharyngeal Carcinoma
Open the PDF for Clonal Mutations Activate the NF-κB Pathway to Promote Recurrence of Nasopharyngeal Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 4651: Polo-like kinase 1 phosphorylates and stabilizes KLF4 to promote tumorigenesis in nasopharyngeal carcinoma

Jia Mai, Zhuo-Yan Zhong, Xiu-Xing Chen, Yan-Qun Xiang, Xuan Li, Hai-Liang Zhang, Rong Deng, Xiao-Feng Zhu
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4651.
https://doi.org/10.1158/1538-7445.AM2019-4651
Published: 01 July 2019
View article titled, Abstract 4651: Polo-like kinase 1 phosphorylates and stabilizes KLF4 to promote tumorigenesis in nasopharyngeal carcinoma
Journal Articles

Abstract 4950: Abnormality of selective autophagic degradation of tenascin-C promotes resistance to T cell-mediated immune attack in triple negative breast cancer

Rong Deng, Zhi-ling Li, Hai-Liang Zhang, Xuan Li, Jia Mia, Li-Huan Zhou, Yun Huang, Yan Yu, Jun Tang, Xiao-Feng Zhu
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4950.
https://doi.org/10.1158/1538-7445.AM2019-4950
Published: 01 July 2019
View article titled, Abstract 4950: Abnormality of selective autophagic degradation of tenascin-C promotes resistance to T cell-mediated immune attack in triple negative breast cancer
Journal Articles

Abstract 2355: IKKa serves as a molecular switch linking miRNA biogenesis and inflammation in skin tumorigenesis

Feng Zhu, Jian Zhang, Jami Willette-Brown, Ling Su, Xiaolin Wu, Yinling Hu
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2355.
https://doi.org/10.1158/1538-7445.AM2019-2355
Published: 01 July 2019
View article titled, Abstract 2355: IKKa serves as a molecular switch linking miRNA biogenesis and inflammation in skin tumorigenesis
Journal Articles

Abstract 38: Mitophagy deficiency promotes osteolytic bone metastasis in breast cancer

Rong Deng, Hai-Liang Zhang, Rui-Zhao Cai, Jun Tang, Xiao-Feng Zhu
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 38.
https://doi.org/10.1158/1538-7445.AM2018-38
Published: 01 July 2018
View article titled, Abstract 38: Mitophagy deficiency promotes osteolytic bone metastasis in breast cancer
Journal Articles

Abstract 2751: Regorafenib attenuates IFN-γ-induced PD-L1 expression and enhances antitumor immunity

Xiao-Feng Zhu
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2751.
https://doi.org/10.1158/1538-7445.AM2018-2751
Published: 01 July 2018
View article titled, Abstract 2751: Regorafenib attenuates IFN-γ-induced PD-L1 expression and enhances antitumor immunity
Journal Articles

Abstract 5008: Crosstalk between epithelial-IKKα-deletion and symbiotic bacterial-fungal infection in skin carcinogenesis

Na-Young Song, Jami Willette-Brown, Feng Zhu, Yinling Hu
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5008.
https://doi.org/10.1158/1538-7445.AM2018-5008
Published: 01 July 2018
View article titled, Abstract 5008: Crosstalk between epithelial-IKKα-deletion and symbiotic bacterial-fungal infection in skin carcinogenesis
Journal Articles

Abstract 536: Targeting PRPK and TOPK for skin cancer prevention and therapy

Eunmiri Roh, Mee-Hyun Lee, Tatyana A. Zykova, Feng Zhu, Hong-Gyum Kim, Ki Beom Bae, Yong Yeon Cho, Ann M. Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 536.
https://doi.org/10.1158/1538-7445.AM2018-536
Published: 01 July 2018
View article titled, Abstract 536: Targeting PRPK and TOPK for skin cancer prevention and therapy
Journal Articles

Abstract 7: Ceftriaxone, an FDA-approved cephalosporin antibiotic, suppresses lung cancer growth by targeting Aurora B

Xiang Li, Haitao Li, Shengqing Li, Feng Zhu, Dong Joon Kim, Hua Xie, Yan Li, Janos Nadas, Naomi Oi, Tatyana Zykova, Dong Hoon Yu, Mee-Hyun Lee, Myoung Ok Kim, Lei Wang, Wei Ya Ma, Ronald A. Lubet, Ann M. Bode, Ziming Dong, Zigang Dong
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 7.
https://doi.org/10.1158/1538-7445.AM2017-7
Published: 01 July 2017
View article titled, Abstract 7: Ceftriaxone, an FDA-approved cephalosporin antibiotic, suppresses lung cancer growth by targeting Aurora B
Journal Articles

Abstract 1986: Determining the signaling pathway of epithelial-IKKα deletion-mediated symbiotic bacterial and fungal infection in carcinogenesis

Na-Young Song, Jami Willette-Brown, Feng Zhu, Yinling Hu
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1986.
https://doi.org/10.1158/1538-7445.AM2017-1986
Published: 01 July 2017
View article titled, Abstract 1986: Determining the signaling pathway of epithelial-IKKα deletion-mediated symbiotic bacterial and fungal infection in carcinogenesis
Journal Articles

Abstract 4802: Immune dysfunction and fungal infection contribute to esophageal carcinogenesis

Feng Zhu, Jami Willette-Brown, Na-young Song, Peilin Zhang, Yinling Hu
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4802.
https://doi.org/10.1158/1538-7445.AM2017-4802
Published: 01 July 2017
View article titled, Abstract 4802: Immune dysfunction and fungal infection contribute to esophageal carcinogenesis
Journal Articles

Abstract 3509: Knockdown of RNF2 induces apoptosis by regulating MDM2 and p53 stability

Weihong Wen, Cong Peng, Myoung Ok Kim, Chul Ho Jeong, Feng Zhu, Ke Yao, Tatyana Zykova, Wei-Ya Ma, Andria Carper, Alyssa Langfald, Ann M. Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3509.
https://doi.org/10.1158/1538-7445.AM2016-3509
Published: 15 July 2016
View article titled, Abstract 3509: Knockdown of RNF2 induces apoptosis by regulating MDM2 and p53 stability
Journal Articles

Abstract LB-139: Tissue stem cell specific enhancer element identifies two types of stem cells in the corpus epithelium of the stomach

Junichi Matsuo, Shunichi Kimura, Cai Ping Koh, Md Zakir Hossain, Akihiro Yamamura, Kazuyoshi Kohu, Michiaki Unno, Jimmy Bok Yan So, Feng Zhu, Supriya Srivastava, Teh Meng, Nicholas Barker, Khay Guan Yeoh, Motomi Osato, Yoshiaki Ito
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): LB-139.
https://doi.org/10.1158/1538-7445.AM2015-LB-139
Published: 01 August 2015
View article titled, Abstract LB-139: Tissue stem cell specific enhancer element identifies two types of stem cells in the corpus epithelium of the stomach