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Journal Articles

Abstract LB380: A novel LNP-Encapsulated mRNA vaccine reshapes the immune microenvironment to overcome immunotherapy and chemotherapy resistance in esophageal squamous cell carcinoma with PIK3CA hotspot mutation

Feng Wang, Rui-Hua Xu, Yu Xu, Yue Huang, Yijun Gao

Cancer Res (2025) 85 (8_Supplement_2): LB380.

https://doi.org/10.1158/1538-7445.AM2025-LB380

Published: 25 April 2025

View articletitled, Abstract LB380: A novel LNP-Encapsulated mRNA vaccine reshapes the immune microenvironment to overcome immunotherapy and chemotherapy resistance in esophageal squamous cell carcinoma with PIK3CA hotspot mutation

Journal Articles

Abstract 2976: XPR1 and SLC34A2 (NaPi2B)- A tale of targeting the phosphate homeostasis in cancer cells

Cancer Res (2025) 85 (8_Supplement_1): 2976.

https://doi.org/10.1158/1538-7445.AM2025-2976

Published: 21 April 2025

View articletitled, Abstract 2976: XPR1 and SLC34A2 (NaPi2B)- A tale of targeting the phosphate homeostasis in cancer cells

Journal Articles

The Functional Transcriptomic Landscape Informs Therapeutic Strategies in Multiple Myeloma

Cancer Res (2025) 85 (2): 378–398.

https://doi.org/10.1158/0008-5472.CAN-24-0886

Published: 15 January 2025

View articletitled, The Functional Transcriptomic Landscape Informs Therapeutic Strategies in Multiple Myeloma

Includes: Supplementary data

Journal Articles

HDAC Inhibition Increases CXCL12 Secretion to Recruit Natural Killer Cells in Peripheral T-cell Lymphoma

Jiayan Zhu, Feng Wang, Lining Wang, Bo Dai, Guilin Xu, Luyao Zhao, Huimin Jiang, Wenhui Gao, Tingting Zhang, Chenxi Zhao, Yun-Xuan Li, Jiong Hu, Ke Li

Cancer Res (2024) 84 (15): 2450–2467.

https://doi.org/10.1158/0008-5472.CAN-23-3250

Published: 01 August 2024

View articletitled, HDAC Inhibition Increases CXCL12 Secretion to Recruit Natural Killer Cells in Peripheral T-cell Lymphoma

Includes: Supplementary data

Journal Articles

Abstract LB269: XZP-6924: A potent and highly selective USP1 inhibitor with the potential to improve efficacy and overcome resistance to PARP inhibitors

Zhihui Kan, Shujin Bai, Kelin Ma, Bo Chen, Benke Jiang, Feng Wang, Xifeng Ma, Dapeng Zhou, Chunmin Shi, Yanfang Nie, Yunling Wang, Ruxiao Liu, Jun Sun, Huimin Zhou, Mei Xu, Jiakui Li, Bin Liu

Cancer Res (2024) 84 (7_Supplement): LB269.

https://doi.org/10.1158/1538-7445.AM2024-LB269

Published: 05 April 2024

View articletitled, Abstract LB269: XZP-6924: A potent and highly selective USP1 inhibitor with the potential to improve efficacy and overcome resistance to PARP inhibitors

Journal Articles

Abstract LB268: Discovery of a potent, selective and brain penetrating PARP1 inhibitor, XZP-7797

Yeqing Gao, Yuqian Lu, Bo Chen, Benke Jiang, Feng Wang, Genyan Zhang, Xifeng Ma, Dapeng Zhou, Chunmin Shi, Yunling Wang, Zhipeng Liu, Jun Sun, Huimin Zhou, Mei Xu, Jiakui Li, Bin Liu

Cancer Res (2024) 84 (7_Supplement): LB268.

https://doi.org/10.1158/1538-7445.AM2024-LB268

Published: 05 April 2024

View articletitled, Abstract LB268: Discovery of a potent, selective and brain penetrating PARP1 inhibitor, XZP-7797

Journal Articles

Abstract LB272: Sequential inhibition of PARP and BET as a rational therapeutic strategy for glioblastoma multiforme

Cancer Res (2024) 84 (7_Supplement): LB272.

https://doi.org/10.1158/1538-7445.AM2024-LB272

Published: 05 April 2024

View articletitled, Abstract LB272: Sequential inhibition of PARP and BET as a rational therapeutic strategy for glioblastoma multiforme

Journal Articles

Abstract 2788: Immunological targeting of integrin β1^high/β3^high melanoma

Feng Wang, Ying Xin, James J. Moon, Alfred E. Chang, Max Wicha, Qiao Li

Cancer Res (2024) 84 (6_Supplement): 2788.

https://doi.org/10.1158/1538-7445.AM2024-2788

Published: 22 March 2024

View articletitled, Abstract 2788: Immunological targeting of integrin β1high/β3high melanoma

Journal Articles

Abstract 1855: Targeting DGKA for immuno-oncology therapy: ISM4312A, a novel DGKA inhibitor with robust anti-tumor activity

Deheng Sun, Hongfu Lu, Huaxing Yu, Feng Wang, Mike Korzinkin, Xin Cai, Xiao Ding, Sujata Rao, Feng Ren, Alex Zhavoronkov

Cancer Res (2023) 83 (7_Supplement): 1855.

https://doi.org/10.1158/1538-7445.AM2023-1855

Published: 04 April 2023

View articletitled, Abstract 1855: Targeting DGKA for immuno-oncology therapy: ISM4312A, a novel DGKA inhibitor with robust anti-tumor activity

Journal Articles

Abstract 4760: KDM4A promotes NEPC progression through regulation of MYC expression

Cancer Res (2023) 83 (7_Supplement): 4760.

https://doi.org/10.1158/1538-7445.AM2023-4760

Published: 04 April 2023

View articletitled, Abstract 4760: KDM4A promotes NEPC progression through regulation of MYC expression

Journal Articles

Abstract 5588: PD-1 blockade synergizes with IMiDs to enhance bispecific T cell engager immune responses to Vk*MYC^hCRBN multiple myeloma by preventing T cell exhaustion

Erin W. Meermeier, Seth J. Welsh, Meaghen Sharik, Megan T. Du, Chang-Xin Shi, Bryant Chau, Feng Wang, Matthew Wheeler, Natalie Bezman, Pavel Strop, P. Leif Bergsagel, Marta Chesi

Cancer Res (2022) 82 (12_Supplement): 5588.

https://doi.org/10.1158/1538-7445.AM2022-5588

Published: 15 June 2022

View articletitled, Abstract 5588: PD-1 blockade synergizes with IMiDs to enhance bispecific T cell engager immune responses to Vk*MYChCRBN multiple myeloma by preventing T cell exhaustion

Journal Articles

Abstract 5519: Selinexor synergizes with anti-PD-1 antibody and inhibits tumor growth and metastasis in syngeneic mouse models of KRAS mutant colorectal cancer

Hua Chang, Leah Henegar, Christopher J. Walker, Trinayan Kashyap, Marie Maloof, Feng Wang, Kathleen Martyn, Shira Orr, Michael G. Kauffman, Sharon Shacham, Yosef Landesman

Cancer Res (2022) 82 (12_Supplement): 5519.

https://doi.org/10.1158/1538-7445.AM2022-5519

Published: 15 June 2022

View articletitled, Abstract 5519: Selinexor synergizes with anti-PD-1 antibody and inhibits tumor growth and metastasis in syngeneic mouse models of KRAS mutant colorectal cancer

Journal Articles

Abstract 5455: Nuclear export inhibitor selinexor synergizes with proteasome inhibitor marizomib in preclinical models of glioblastoma

Hua Chang, Leah Henegar, Christopher J. Walker, Trinayan Kashyap, Marie Maloof, Feng Wang, Kathleen Martyn, Shira Orr, Sharon Tamir, Michael G. Kauffman, Sharon Shacham, Yosef Landesman

Cancer Res (2022) 82 (12_Supplement): 5455.

https://doi.org/10.1158/1538-7445.AM2022-5455

Published: 15 June 2022

View articletitled, Abstract 5455: Nuclear export inhibitor selinexor synergizes with proteasome inhibitor marizomib in preclinical models of glioblastoma

Journal Articles

Abstract 6023: Selinexor synergizes with temozolomide in preclinical models of glioblastoma independent of MGMT promoter methylation

Leah Henegar, Hua Chang, Christopher J. Walker, Trinayan Kashyap, Marie Maloof, Feng Wang, Kathleen Martyn, Shira Orr, Sharon Tamir, Michael G. Kauffman, Sharon Shacham, Yosef Landesman

Cancer Res (2022) 82 (12_Supplement): 6023.

https://doi.org/10.1158/1538-7445.AM2022-6023

Published: 15 June 2022

View articletitled, Abstract 6023: Selinexor synergizes with temozolomide in preclinical models of glioblastoma independent of MGMT promoter methylation

Journal Articles

Abstract 6022: Synergistic anti-cancer effects of selinexor and bevacizumab in mouse xenograft models of glioblastoma

Leah Henegar, Hua Chang, Christopher J. Walker, Trinayan Kashyap, Marie Maloof, Feng Wang, Kathleen Martyn, Shira Orr, Sharon Tamir, Michael G. Kauffman, Sharon Shacham, Yosef Landesman

Cancer Res (2022) 82 (12_Supplement): 6022.

https://doi.org/10.1158/1538-7445.AM2022-6022

Published: 15 June 2022

View articletitled, Abstract 6022: Synergistic anti-cancer effects of selinexor and bevacizumab in mouse xenograft models of glioblastoma

Journal Articles

Abstract 1122: Selinexor synergizes with IL-12 to inhibit tumor growth in syngeneic mouse models of melanoma

Shira Orr, Leah Henegar, Christopher J. Walker, Feng Wang, Trinayan Kashyap, Marie Maloof, Kathleen Martyn, Michael G. Kauffman, Sharon Shacham, Yosef Landesman

Cancer Res (2022) 82 (12_Supplement): 1122.

https://doi.org/10.1158/1538-7445.AM2022-1122

Published: 15 June 2022

View articletitled, Abstract 1122: Selinexor synergizes with IL-12 to inhibit tumor growth in syngeneic mouse models of melanoma

Journal Articles

Functional Analysis of MET Exon 14 Skipping Alteration in Cancer Invasion and Metastatic Dissemination

Feng Wang, Yang Liu, Wanglong Qiu, Elaine Shum, Monica Feng, Dejian Zhao, Deyou Zheng, Alain Borczuk, Haiying Cheng, Balazs Halmos

Cancer Res (2022) 82 (7): 1365–1379.

https://doi.org/10.1158/0008-5472.CAN-21-1327

Published: 01 April 2022

View articletitled, Functional Analysis of MET Exon 14 Skipping Alteration in Cancer Invasion and Metastatic Dissemination

Includes: Supplementary data

Journal Articles

Abstract P3-06-05: Human endogenous retrovirus-K (HERV-K) is aberrantly expressed in triple negative breast cancer (TNBC) and associated with increased distant metastasis: Impact of HERV-K knockdown on gene expression patterns and invasive potential of mesenchymal TNBC

Sharon A Glynn, Dibyangana Bhattacharyya, Shauna Lambe, Emma Kerr, Simon McDade, Faizan H Khan, Eoin Dervan, Feng Wang-Johanning, Sean Hynes, Grace Callagy

Cancer Res (2022) 82 (4_Supplement): P3-06-05.

https://doi.org/10.1158/1538-7445.SABCS21-P3-06-05

Published: 15 February 2022

View articletitled, Abstract P3-06-05: Human endogenous retrovirus-K (HERV-K) is aberrantly expressed in triple negative breast cancer (TNBC) and associated with increased distant metastasis: Impact of HERV-K knockdown on gene expression patterns and invasive potential of mesenchymal TNBC

Journal Articles

Abstract 1981: TGF-β induced PLEK2 promotes metastasis and chemoresistance in ESCC by up-regulation of LCN2

Feng Wang, Chaoqi Zhang, Chengming Liu, Hong Cheng, Nan Sun, Jie He

Cancer Res (2021) 81 (13_Supplement): 1981.

https://doi.org/10.1158/1538-7445.AM2021-1981

Published: 01 July 2021

View articletitled, Abstract 1981: TGF-β induced PLEK2 promotes metastasis and chemoresistance in ESCC by up-regulation of LCN2

Journal Articles

Abstract 146: DNA methylation age of paired tumor-normal breast tissue in Chinese women with breast cancer

Hela Koka, Bin Zhu, Shelly Lap Ah Tse, Difei Wang, Maeve Kiely, Jennifer Lyn Guida, Priscilla Lee, Feng Wang, Cherry Wu, Koon Ho Tsang, Wing-cheong Chan, Sze Hong Law, Eric Karlins, Bin Zhu, Amy Hutchinson, Belynda Hicks, Xiaohong R. Yang

Cancer Res (2020) 80 (16_Supplement): 146.

https://doi.org/10.1158/1538-7445.AM2020-146

Published: 15 August 2020

View articletitled, Abstract 146: DNA methylation age of paired tumor-normal breast tissue in Chinese women with breast cancer

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Abstract LB380: A novel LNP-Encapsulated mRNA vaccine reshapes the immune microenvironment to overcome immunotherapy and chemotherapy resistance in esophageal squamous cell carcinoma with PIK3CA hotspot mutation

Abstract 2976: XPR1 and SLC34A2 (NaPi2B)- A tale of targeting the phosphate homeostasis in cancer cells

The Functional Transcriptomic Landscape Informs Therapeutic Strategies in Multiple Myeloma

HDAC Inhibition Increases CXCL12 Secretion to Recruit Natural Killer Cells in Peripheral T-cell Lymphoma

Abstract LB269: XZP-6924: A potent and highly selective USP1 inhibitor with the potential to improve efficacy and overcome resistance to PARP inhibitors

Abstract LB268: Discovery of a potent, selective and brain penetrating PARP1 inhibitor, XZP-7797

Abstract LB272: Sequential inhibition of PARP and BET as a rational therapeutic strategy for glioblastoma multiforme

Abstract 2788: Immunological targeting of integrin β1^high/β3^high melanoma

Abstract 1855: Targeting DGKA for immuno-oncology therapy: ISM4312A, a novel DGKA inhibitor with robust anti-tumor activity

Abstract 4760: KDM4A promotes NEPC progression through regulation of MYC expression

Abstract 5588: PD-1 blockade synergizes with IMiDs to enhance bispecific T cell engager immune responses to Vk*MYC^hCRBN multiple myeloma by preventing T cell exhaustion

Abstract 5519: Selinexor synergizes with anti-PD-1 antibody and inhibits tumor growth and metastasis in syngeneic mouse models of KRAS mutant colorectal cancer

Abstract 5455: Nuclear export inhibitor selinexor synergizes with proteasome inhibitor marizomib in preclinical models of glioblastoma

Abstract 6023: Selinexor synergizes with temozolomide in preclinical models of glioblastoma independent of MGMT promoter methylation

Abstract 6022: Synergistic anti-cancer effects of selinexor and bevacizumab in mouse xenograft models of glioblastoma

Abstract 1122: Selinexor synergizes with IL-12 to inhibit tumor growth in syngeneic mouse models of melanoma

Functional Analysis of MET Exon 14 Skipping Alteration in Cancer Invasion and Metastatic Dissemination

Abstract P3-06-05: Human endogenous retrovirus-K (HERV-K) is aberrantly expressed in triple negative breast cancer (TNBC) and associated with increased distant metastasis: Impact of HERV-K knockdown on gene expression patterns and invasive potential of mesenchymal TNBC

Abstract 1981: TGF-β induced PLEK2 promotes metastasis and chemoresistance in ESCC by up-regulation of LCN2

Abstract 146: DNA methylation age of paired tumor-normal breast tissue in Chinese women with breast cancer

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