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Journal Articles

An Atlas of Accessible Chromatin in Advanced Prostate Cancer Reveals the Epigenetic Evolution during Tumor Progression

Raunak Shrestha, Lisa N. Chesner, Meng Zhang, Stanley Zhou, Adam Foye, Arian Lundberg, Alana S. Weinstein, Martin Sjöström, Xiaolin Zhu, Thaidy Moreno-Rodriguez, Haolong Li, SU2C/PCF West Coast Prostate Cancer Dream Team, Joshi J. Alumkal, Rahul Aggarwal, Eric J. Small, Mathieu Lupien, David A. Quigley, Felix Y. Feng

Cancer Res (2024) 84 (18): 3086–3100.

https://doi.org/10.1158/0008-5472.CAN-24-0890

Published: 16 September 2024

View articletitled, An Atlas of Accessible Chromatin in Advanced Prostate Cancer Reveals the Epigenetic Evolution during Tumor Progression

Includes: Supplementary data

Journal Articles

Abstract LB196: An atlas of accessible chromatin in advanced prostate cancer

Raunak Shrestha, Lisa N. Chesner, Meng Zhang, Stanley Zhou, Adam Foye, Arian Lundberg, Alana S. Weinstein, Martin Sjöström, Xiaolin Zhu, Thaidy Moreno-Rodriguez, Haolong Li, Joshi J. Alumkal, Rahul Aggarwal, Eric J. Small, Mathieu Lupien, David A. Quigley, Felix Y. Feng

Cancer Res (2024) 84 (7_Supplement): LB196.

https://doi.org/10.1158/1538-7445.AM2024-LB196

Published: 05 April 2024

View articletitled, Abstract LB196: An atlas of accessible chromatin in advanced prostate cancer

Journal Articles

Abstract 4988: Responders to combination radiation and PD-1 blockade demonstrate reduced myeloid immunosuppression and enhanced interferon signaling in oligometastatic prostate cancer patients

Zenghua Fan, David Y. Oh, Anthony Wong, Katsuto Shinohara, Hao Nguyen, Caleb Hwang, Hewitt Chang, Alec Starzinski, Tony Li, Christopher De Leon, Marissa Gin, Eliezer Van Allen, Li Zhang, Rahaul R. Aggarwal, Terence W. Friedlander, Eric J. Small, Felix Y. Feng, Lawrence Fong

Cancer Res (2024) 84 (6_Supplement): 4988.

https://doi.org/10.1158/1538-7445.AM2024-4988

Published: 22 March 2024

View articletitled, Abstract 4988: Responders to combination radiation and PD-1 blockade demonstrate reduced myeloid immunosuppression and enhanced interferon signaling in oligometastatic prostate cancer patients

Journal Articles

The Genomic and Epigenomic Landscape of Double-Negative Metastatic Prostate Cancer

Cancer Res (2023) 83 (16): 2763–2774.

https://doi.org/10.1158/0008-5472.CAN-23-0593

Published: 15 August 2023

View articletitled, The Genomic and Epigenomic Landscape of Double-Negative Metastatic Prostate Cancer

Includes: Supplementary data

Journal Articles

Abstract B012: Genomic and epigenomic drivers of double-negative metastatic prostate cancer

Cancer Res (2023) 83 (11_Supplement): B012.

https://doi.org/10.1158/1538-7445.PRCA2023-B012

Published: 02 June 2023

View articletitled, Abstract B012: Genomic and epigenomic drivers of double-negative metastatic prostate cancer

Journal Articles

Abstract B066: Genome-wide CRISPR screens identify PTGES3 as a druggable AR modulator

Cancer Res (2023) 83 (11_Supplement): B066.

https://doi.org/10.1158/1538-7445.PRCA2023-B066

Published: 02 June 2023

View articletitled, Abstract B066: Genome-wide CRISPR screens identify PTGES3 as a druggable AR modulator

Journal Articles

Abstract A027: Identification and characterization of PLUTO-201, a novel lncRNA associated with prostate cancer metastasis

Cancer Res (2023) 83 (11_Supplement): A027.

https://doi.org/10.1158/1538-7445.PRCA2023-A027

Published: 02 June 2023

View articletitled, Abstract A027: Identification and characterization of PLUTO-201, a novel lncRNA associated with prostate cancer metastasis

Journal Articles

Abstract A062: Alternative promoter usage is linked to transcriptional and epigenetic alterations during prostate cancer progression

Meng Zhang, Martin Sjöström, Raunak Shrestha, Arian Lundberg, Thaidy Moreno-Rodriguez, Adam Foye, Ha X. Dang, Joshi J. Alumkal, Rahul Aggarwal, Eric J. Small, Christopher A. Maher, Felix Y. Feng, David Quigley

Cancer Res (2023) 83 (11_Supplement): A062.

https://doi.org/10.1158/1538-7445.PRCA2023-A062

Published: 02 June 2023

View articletitled, Abstract A062: Alternative promoter usage is linked to transcriptional and epigenetic alterations during prostate cancer progression

Journal Articles

DNA Methylation Landscapes of Prostate Cancer Brain Metastasis Are Shaped by Early Driver Genetic Alterations

Cancer Res (2023) 83 (8): 1203–1213.

https://doi.org/10.1158/0008-5472.CAN-22-2236

Published: 14 April 2023

View articletitled, DNA Methylation Landscapes of Prostate Cancer Brain Metastasis Are Shaped by Early Driver Genetic Alterations

Includes: Supplementary data

Journal Articles

Abstract 5471: Integrating tumor-intrinsic and immunological factors to identify immunogenic breast cancers from a low-risk cohort; results from the randomized SweBCG91RT trial

Axel Stenmark Tullberg, Martin Sjöström, Emma Niméus, Fredrik Killander, Laura Chang, Felix Y. Feng, Corey W. Speers, Lori J. Pierce, Anokó Kovács, Dan Lundstedt, Erik Holmberg, Per Karlsson

Cancer Res (2023) 83 (7_Supplement): 5471.

https://doi.org/10.1158/1538-7445.AM2023-5471

Published: 04 April 2023

View articletitled, Abstract 5471: Integrating tumor-intrinsic and immunological factors to identify immunogenic breast cancers from a low-risk cohort; results from the randomized SweBCG91RT trial

Journal Articles

Abstract P4-02-12: Validation of Profile for the Omission of Local Adjuvant Radiotherapy (POLAR) in early-stage invasive breast cancer patients of the Scottish Conservation Trial

Karen J. Taylor, John MS Bartlett, John Bennett, S. Laura Chang, Bradley Arrick, Frederick Baehner, Joseph F. Loane, Tammy Piper, Elizabeth Mallon, Joanna Dunlop, Wilma J. Jack, Jacqueline Caldwell, Ian Kunkler, Linda J. Williams, Corey W. Speers, Felix Y. Feng, Lori Pierce, David A. Cameron

Cancer Res (2023) 83 (5_Supplement): P4-02-12.

https://doi.org/10.1158/1538-7445.SABCS22-P4-02-12

Published: 01 March 2023

View articletitled, Abstract P4-02-12: Validation of Profile for the Omission of Local Adjuvant Radiotherapy (POLAR) in early-stage invasive breast cancer patients of the Scottish Conservation Trial

Journal Articles

Abstract GS4-03: Validation of Profile for the Omission of Local Adjuvant Radiotherapy (POLAR) in a meta-analysis of three randomized controlled trials of breast conserving surgery +/- radiotherapy

Cancer Res (2023) 83 (5_Supplement): GS4-03.

https://doi.org/10.1158/1538-7445.SABCS22-GS4-03

Published: 01 March 2023

View articletitled, Abstract GS4-03: Validation of Profile for the Omission of Local Adjuvant Radiotherapy (POLAR) in a meta-analysis of three randomized controlled trials of breast conserving surgery +/- radiotherapy

Journal Articles

Immunotherapeutic Targeting and PET Imaging of DLL3 in Small-Cell Neuroendocrine Prostate Cancer

Cancer Res (2023) 83 (2): 301–315.

https://doi.org/10.1158/0008-5472.CAN-22-1433

Published: 18 January 2023

View articletitled, Immunotherapeutic Targeting and PET Imaging of DLL3 in Small-Cell Neuroendocrine Prostate Cancer

Includes: Multimedia, Supplementary data

Journal Articles

The 5-Hydroxymethylcytosine Landscape of Prostate Cancer

Martin Sjöström, Shuang G. Zhao, Samuel Levy, Meng Zhang, Yuhong Ning, Raunak Shrestha, Arian Lundberg, Cameron Herberts, Adam Foye, Rahul Aggarwal, Junjie T. Hua, Haolong Li, Anna Bergamaschi, Corinne Maurice-Dror, Ashutosh Maheshwari, Sujun Chen, Sarah W.S. Ng, Wenbin Ye, Jessica Petricca, Michael Fraser, Lisa Chesner, Marc D. Perry, Thaidy Moreno-Rodriguez, William S. Chen, Joshi J. Alumkal, Jonathan Chou, Alicia K. Morgans, Tomasz M. Beer, George V. Thomas, Martin Gleave, Paul Lloyd, Tierney Phillips, Erin McCarthy, Michael C. Haffner, Amina Zoubeidi, Matti Annala, Robert E. Reiter, Matthew B. Rettig, Owen N. Witte, Lawrence Fong, Rohit Bose, Franklin W. Huang, Jianhua Luo, Anders Bjartell, Joshua M. Lang, Nupam P. Mahajan, Primo N. Lara, Christopher P. Evans, Phuoc T. Tran, Edwin M. Posadas, Chuan He, Xiao-Long Cui, Jiaoti Huang, Wilbert Zwart, Luke A. Gilbert, Christopher A. Maher, Paul C. Boutros, Kim N. Chi, Alan Ashworth, Eric J. Small, Housheng H. He, Alexander W. Wyatt, David A. Quigley, Felix Y. Feng

Cancer Res (2022) 82 (21): 3888–3902.

https://doi.org/10.1158/0008-5472.CAN-22-1123

Published: 02 November 2022

View articletitled, The 5-Hydroxymethylcytosine Landscape of Prostate Cancer

Includes: Supplementary data

Journal Articles

Resistance to ATR Inhibitors Is Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2

Patrick C. O'Leary, Huadong Chen, Yagmur U. Doruk, Tess Williamson, Benjamin Polacco, Andrew S. McNeal, Tanushree Shenoy, Nupura Kale, Julia Carnevale, Erica Stevenson, David A. Quigley, Jonathan Chou, Felix Y. Feng, Danielle L. Swaney, Nevan J. Krogan, Minkyu Kim, Morgan E. Diolaiti, Alan Ashworth

Cancer Res (2022) 82 (21): 3950–3961.

https://doi.org/10.1158/0008-5472.CAN-21-4335

Published: 02 November 2022

View articletitled, Resistance to ATR Inhibitors Is Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2

Includes: Supplementary data

Journal Articles

Abstract 3625: Clonal architecture and evolution of treatment-resistant prostate cancer via deep whole-genome ctDNA sequencing

Cancer Res (2022) 82 (12_Supplement): 3625.

https://doi.org/10.1158/1538-7445.AM2022-3625

Published: 15 June 2022

View articletitled, Abstract 3625: Clonal architecture and evolution of treatment-resistant prostate cancer via deep whole-genome ctDNA sequencing

Journal Articles

Loss of Long Noncoding RNA NXTAR in Prostate Cancer Augments Androgen Receptor Expression and Enzalutamide Resistance

Ruchi Ghildiyal, Mithila Sawant, Arun Renganathan, Kiran Mahajan, Eric H. Kim, Jingqin Luo, Ha X. Dang, Christopher A. Maher, Felix Y. Feng, Nupam P. Mahajan

Cancer Res (2022) 82 (1): 155–168.

https://doi.org/10.1158/0008-5472.CAN-20-3845

Published: 04 January 2022

View articletitled, Loss of Long Noncoding RNA NXTAR in Prostate Cancer Augments Androgen Receptor Expression and Enzalutamide Resistance

Includes: Supplementary data

Journal Articles

Abstract 5447: Gene expression of circulating tumor cells is predictive of treatment response in patients with advanced prostate cancer

PAI-CHI TENG, Minhyung Kim, Yu Jen Jan, Jie-Fu Chen, Nu Yao, Gina C. Chu, Pin-Jung Chen, Jasmine J. Wang, Yi-Te Lee, Yazhen Zhu, Leland W. Chung, Felix Y. Feng, Michael R. Freeman, Sungyong You, Hsian-Rong Tseng, Edwin M. Posadas

Cancer Res (2020) 80 (16_Supplement): 5447.

https://doi.org/10.1158/1538-7445.AM2020-5447

Published: 15 August 2020

View articletitled, Abstract 5447: Gene expression of circulating tumor cells is predictive of treatment response in patients with advanced prostate cancer

Journal Articles

Correction: Activation of MAPK Signaling by CXCR7 Leads to Enzalutamide Resistance in Prostate Cancer

Shangze Li, Ka-wing Fong, Galina Gritsina, Ali Zhang, Jonathan C. Zhao, Jung Kim, Adam Sharp, Wei Yuan, Caterina Aversa, Ximing J. Yang, Peter S. Nelson, Felix Y. Feng, Arul M. Chinnaiyan, Johann S. de Bono, Colm Morrissey, Matthew B. Rettig, Jindan Yu

Cancer Res (2020) 80 (10): 2072.

https://doi.org/10.1158/0008-5472.CAN-20-0768

Published: 15 May 2020

View articletitled, Correction: Activation of MAPK Signaling by CXCR7 Leads to Enzalutamide Resistance in Prostate Cancer

Journal Articles

Abstract 2539: Discovery of degradation pathway for maternal embryonic leucine zipper kinase (MELK): Implications for breast cancer therapy

Shyam Nyati, Benjamin Chandler, Anna Michmerhuizen, Andrea Pesch, Cassandra Ritter, Leah Moubadder, Meilan Liu, Meleah Cameron, Eric Olsson, Kari Wilder-Romans, Dipankar Ray, Theodore S. Lawrence, Felix Y. Feng, Lori J. Pierce, Corey Speers

Cancer Res (2019) 79 (13_Supplement): 2539.

https://doi.org/10.1158/1538-7445.AM2019-2539

Published: 01 July 2019

View articletitled, Abstract 2539: Discovery of degradation pathway for maternal embryonic leucine zipper kinase (MELK): Implications for breast cancer therapy

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An Atlas of Accessible Chromatin in Advanced Prostate Cancer Reveals the Epigenetic Evolution during Tumor Progression

Abstract LB196: An atlas of accessible chromatin in advanced prostate cancer

Abstract 4988: Responders to combination radiation and PD-1 blockade demonstrate reduced myeloid immunosuppression and enhanced interferon signaling in oligometastatic prostate cancer patients

The Genomic and Epigenomic Landscape of Double-Negative Metastatic Prostate Cancer

Abstract B012: Genomic and epigenomic drivers of double-negative metastatic prostate cancer

Abstract B066: Genome-wide CRISPR screens identify PTGES3 as a druggable AR modulator

Abstract A027: Identification and characterization of PLUTO-201, a novel lncRNA associated with prostate cancer metastasis

Abstract A062: Alternative promoter usage is linked to transcriptional and epigenetic alterations during prostate cancer progression

DNA Methylation Landscapes of Prostate Cancer Brain Metastasis Are Shaped by Early Driver Genetic Alterations

Abstract 5471: Integrating tumor-intrinsic and immunological factors to identify immunogenic breast cancers from a low-risk cohort; results from the randomized SweBCG91RT trial

Abstract P4-02-12: Validation of Profile for the Omission of Local Adjuvant Radiotherapy (POLAR) in early-stage invasive breast cancer patients of the Scottish Conservation Trial

Abstract GS4-03: Validation of Profile for the Omission of Local Adjuvant Radiotherapy (POLAR) in a meta-analysis of three randomized controlled trials of breast conserving surgery +/- radiotherapy

Immunotherapeutic Targeting and PET Imaging of DLL3 in Small-Cell Neuroendocrine Prostate Cancer

The 5-Hydroxymethylcytosine Landscape of Prostate Cancer

Resistance to ATR Inhibitors Is Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2

Abstract 3625: Clonal architecture and evolution of treatment-resistant prostate cancer via deep whole-genome ctDNA sequencing

Loss of Long Noncoding RNA NXTAR in Prostate Cancer Augments Androgen Receptor Expression and Enzalutamide Resistance

Abstract 5447: Gene expression of circulating tumor cells is predictive of treatment response in patients with advanced prostate cancer

Correction: Activation of MAPK Signaling by CXCR7 Leads to Enzalutamide Resistance in Prostate Cancer

Abstract 2539: Discovery of degradation pathway for maternal embryonic leucine zipper kinase (MELK): Implications for breast cancer therapy

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