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Felix Y. Feng
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Journal Articles

Abstract 3625: Clonal architecture and evolution of treatment-resistant prostate cancer via deep whole-genome ctDNA sequencing

Cameron Herberts, Matti Annala, Joonatan Sipola, Sarah W. Ng, Xinyi E. Chen, Anssi Nurminen, Olga Korhonen, Aslı D. Munzur, Kevin Beja, Elena Schönlau, Cecily Q. Bernales, Elie Ritch, Jack V. Bacon, Nathan A. Lack, Matti Nykter, Rahul Aggarwal, Eric J. Small, Martin E. Gleave, David A. Quigley, Felix Y. Feng, Kim N. Chi, Alexander W. Wyatt
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3625.
DOI: https://doi.org/10.1158/1538-7445.AM2022-3625
Published: 15 June 2022
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Journal Articles

Loss of Long Noncoding RNA NXTAR in Prostate Cancer Augments Androgen Receptor Expression and Enzalutamide Resistance

Ruchi Ghildiyal, Mithila Sawant, Arun Renganathan, Kiran Mahajan, Eric H. Kim, Jingqin Luo, Ha X. Dang, Christopher A. Maher, Felix Y. Feng, Nupam P. Mahajan
Journal: Cancer Research
Cancer Res (2022) 82 (1): 155–168.
DOI: https://doi.org/10.1158/0008-5472.CAN-20-3845
Published: 04 January 2022
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Includes: Supplementary data
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Abstract 5447: Gene expression of circulating tumor cells is predictive of treatment response in patients with advanced prostate cancer

PAI-CHI TENG, Minhyung Kim, Yu Jen Jan, Jie-Fu Chen, Nu Yao, Gina C. Chu, Pin-Jung Chen, Jasmine J. Wang, Yi-Te Lee, Yazhen Zhu, Leland W. Chung, Felix Y. Feng, Michael R. Freeman, Sungyong You, Hsian-Rong Tseng, Edwin M. Posadas
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5447.
DOI: https://doi.org/10.1158/1538-7445.AM2020-5447
Published: 15 August 2020
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Journal Articles

Correction: Activation of MAPK Signaling by CXCR7 Leads to Enzalutamide Resistance in Prostate Cancer

Shangze Li, Ka-wing Fong, Galina Gritsina, Ali Zhang, Jonathan C. Zhao, Jung Kim, Adam Sharp, Wei Yuan, Caterina Aversa, Ximing J. Yang, Peter S. Nelson, Felix Y. Feng, Arul M. Chinnaiyan, Johann S. de Bono, Colm Morrissey, Matthew B. Rettig, Jindan Yu
Journal: Cancer Research
Cancer Res (2020) 80 (10): 2072.
DOI: https://doi.org/10.1158/0008-5472.CAN-20-0768
Published: 15 May 2020
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Journal Articles

Abstract 2539: Discovery of degradation pathway for maternal embryonic leucine zipper kinase (MELK): Implications for breast cancer therapy

Shyam Nyati, Benjamin Chandler, Anna Michmerhuizen, Andrea Pesch, Cassandra Ritter, Leah Moubadder, Meilan Liu, Meleah Cameron, Eric Olsson, Kari Wilder-Romans, Dipankar Ray, Theodore S. Lawrence, Felix Y. Feng, Lori J. Pierce, Corey Speers
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2539.
DOI: https://doi.org/10.1158/1538-7445.AM2019-2539
Published: 01 July 2019
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Journal Articles

Activation of MAPK Signaling by CXCR7 Leads to Enzalutamide Resistance in Prostate Cancer

Shangze Li, Ka-wing Fong, Galina Gritsina, Ali Zhang, Jonathan C. Zhao, Jung Kim, Adam Sharp, Wei Yuan, Caterina Aversa, Ximing J. Yang, Peter S. Nelson, Felix Y. Feng, Arul M. Chinnaiyan, Johann S. de Bono, Colm Morrissey, Matthew B. Rettig, Jindan Yu
Journal: Cancer Research
Cancer Res (2019) 79 (10): 2580–2592.
DOI: https://doi.org/10.1158/0008-5472.CAN-18-2812
Published: 15 May 2019
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Includes: Supplementary data
Journal Articles

EWS/ETS-Driven Ewing Sarcoma Requires BET Bromodomain Proteins

Paradesi Naidu Gollavilli, Aishwarya Pawar, Kari Wilder-Romans, Ramakrishnan Natesan, Carl G. Engelke, Vijaya L. Dommeti, Pranathi M. Krishnamurthy, Archana Nallasivam, Ingrid J. Apel, Tianlei Xu, Zhaohui S. Qin, Felix Y. Feng, Irfan A. Asangani
Journal: Cancer Research
Cancer Res (2018) 78 (16): 4760–4773.
DOI: https://doi.org/10.1158/0008-5472.CAN-18-0484
Published: 14 August 2018
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Abstract B040: Differential impact of RB status on E2F1 reprogramming in human cancer

Christopher McNair, Kexin Xu, Amy C. Mandigo, Matteo Benelli, Benjamin Leiby, Daniel Rodrigues, Johan Lindberg, Henrik Gronberg, Mateus Crespo, Bram De Laere, Luc Dirix, Tapio Visakorpi, Fugen Li, Felix Y. Feng, Johann de Bono, Francesca Demichelis, Mark A. Rubin, Myles Brown, Karen E. Knudsen
Journal: Cancer Research
Cancer Res (2018) 78 (16_Supplement): B040.
DOI: https://doi.org/10.1158/1538-7445.PRCA2017-B040
Published: 14 August 2018
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Abstract IA03: Differential impact of RB pathway status on E2F1 reprogramming and disease progression in human prostate cancer

Christopher McNair, Kexin Xu, Amy C. Mandigo, Matteo Benelli, Benjamin Leiby, Daniel Rodrigues, Johan Lindberg, Henrik Gronberg, Bram De Laere, Luc Dirix, Tapio Visakorpi, Fugen Li, Felix Y. Feng, Johann de Bono, Francesca Demichelis, Mark A Rubin, Myles Brown, Karen E. Knudsen
Journal: Cancer Research
Cancer Res (2018) 78 (16_Supplement): IA03.
DOI: https://doi.org/10.1158/1538-7445.PRCA2017-IA03
Published: 14 August 2018
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Journal Articles

Abstract 2605: Androgen receptor (AR) anomalies and efficacy of apalutamide (APA) in patients (pts) with nonmetastatic castration-resistant prostate cancer (nmCRPC) from the phase 3 SPARTAN study

Matthew R. Smith, Shibu Thomas, Simon Chowdhury, David Olmos, Jinhui Li, Paul N. Mainwaring, Stéphane Oudard, Felix Y. Feng, Michael Gormley, Deborah S. Ricci, Brendan Rooney, Angela Lopez-Gitlitz, Margaret K. Yu, Eric J. Small
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2605.
DOI: https://doi.org/10.1158/1538-7445.AM2018-2605
Published: 01 July 2018
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Journal Articles

LSD1-Mediated Epigenetic Reprogramming Drives CENPE Expression and Prostate Cancer Progression

Yi Liang, Musaddeque Ahmed, Haiyang Guo, Fraser Soares, Junjie T. Hua, Shuai Gao, Catherine Lu, Christine Poon, Wanting Han, Jens Langstein, Muhammad B. Ekram, Brian Li, Elai Davicioni, Mandeep Takhar, Nicholas Erho, R. Jeffrey Karnes, Dianne Chadwick, Theodorus van der Kwast, Paul C. Boutros, Cheryl H. Arrowsmith, Felix Y. Feng, Anthony M. Joshua, Amina Zoubeidi, Changmeng Cai, Housheng H. He
Journal: Cancer Research
Cancer Res (2017) 77 (20): 5479–5490.
DOI: https://doi.org/10.1158/0008-5472.CAN-17-0496
Published: 15 October 2017
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Includes: Supplementary data
Journal Articles

Androgen Receptor Variants Mediate DNA Repair after Prostate Cancer Irradiation

Yi Yin, Rui Li, Kangling Xu, Sentai Ding, Jeffrey Li, GuemHee Baek, Susmita G. Ramanand, Sam Ding, Zhao Liu, Yunpeng Gao, Mohammed S. Kanchwala, Xiangyi Li, Ryan Hutchinson, Xihui Liu, Solomon L. Woldu, Chao Xing, Neil B. Desai, Felix Y. Feng, Sandeep Burma, Johann S. de Bono, Scott M. Dehm, Ram S. Mani, Benjamin P.C. Chen, Ganesh V. Raj
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (18): 4745–4754.
DOI: https://doi.org/10.1158/0008-5472.CAN-17-0164
Published: 14 September 2017
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Includes: Supplementary data
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Abstract 2: Functional and mechanistic interrogation of BET bromodomain degraders for the treatment of metastatic castration resistant prostate cancer

Steven Kregel, Rohit Malik, Irfan A. Asangani, Kari Wilder-Romans, Xia Jiang, Ingrid J. Apel, Gautham Ravi, Jean Tien, Xuhong Cao, Felix Y. Feng, Corey Speers, Shaomeng Wang, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2.
DOI: https://doi.org/10.1158/1538-7445.AM2017-2
Published: 01 July 2017
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Journal Articles

Abstract 5839: Androgen receptor (AR): A novel target for radiosensitization in triple-negative breast cancers (TNBC)

Benjamin C. Chandler, Corey W. Speers, Shuang G. Zhao, Meilan Liu, Kari Wilder-Romans, Eric Olsen, Shyam Nyati, Daniel Spratt, Daniel Wahl, Daniel Hayes, Felix Y. Feng, Lori J. Pierce
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5839.
DOI: https://doi.org/10.1158/1538-7445.AM2017-5839
Published: 01 July 2017
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Journal Articles

Abstract 5874: Cdk4/6 kinase inhibitor resistance in prostate cancer

Renee de Leeuw, Matthew J. Schiewer, Christopher McNair, Michael A. Augello, Akihiro Yoshida, Edward S. Hazard, Sean Courtney, Gerard T. Hardiman, Justin Drake, Felix Y. Feng, Scott Tomlins, Maha H. Hussain, J Alan Diehl, William K. Kelly, Karen E. Knudsen
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5874.
DOI: https://doi.org/10.1158/1538-7445.AM2017-5874
Published: 01 July 2017
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Abstract LB-099: BET bromodomain proteins are essential for the oncogenic EWS-fusion driven Ewing Sarcoma

Paradesi N. Gollavilli, Aishwarya Pawar, Kari Wilder-Romans, Carl Engelke, Vijaya L. Dommeti, Pranathi M. Krishnamurthy, Archana Nallasivam, Ingrid A. Apel, Tianlei Xu, Zhaohui S. Qin, Felix Y. Feng, Irfan A. Asangani
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-099.
DOI: https://doi.org/10.1158/1538-7445.AM2017-LB-099
Published: 01 July 2017
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Journal Articles

Glioblastoma Therapy Can Be Augmented by Targeting IDH1-Mediated NADPH Biosynthesis

Daniel R. Wahl, Joseph Dresser, Kari Wilder-Romans, Joshua D. Parsels, Shuang G. Zhao, Mary Davis, Lili Zhao, Maureen Kachman, Stefanie Wernisch, Charles F. Burant, Meredith A. Morgan, Felix Y. Feng, Corey Speers, Costas A. Lyssiotis, Theodore S. Lawrence
Journal: Cancer Research
Cancer Res (2017) 77 (4): 960–970.
DOI: https://doi.org/10.1158/0008-5472.CAN-16-2008
Published: 14 February 2017
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Includes: Supplementary data
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RB Loss Promotes Prostate Cancer Metastasis

Chellappagounder Thangavel, Ettickan Boopathi, Yi Liu, Alex Haber, Adam Ertel, Anshul Bhardwaj, Sankar Addya, Noelle Williams, Stephen J. Ciment, Paolo Cotzia, Jeffry L. Dean, Adam Snook, Chris McNair, Matt Price, James R. Hernandez, Shuang G. Zhao, Ruth Birbe, James B. McCarthy, Eva A. Turley, Kenneth J. Pienta, Felix Y. Feng, Adam P. Dicker, Karen E. Knudsen, Robert B. Den
Journal: Cancer Research
Cancer Res (2017) 77 (4): 982–995.
DOI: https://doi.org/10.1158/0008-5472.CAN-16-1589
Published: 14 February 2017
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Includes: Supplementary data
Journal Articles

MicroRNA-194 Promotes Prostate Cancer Metastasis by Inhibiting SOCS2

Rajdeep Das, Philip A. Gregory, Rayzel C. Fernandes, Iza Denis, Qingqing Wang, Scott L. Townley, Shuang G. Zhao, Adrienne R. Hanson, Marie A. Pickering, Heather K. Armstrong, Noor A. Lokman, Esmaeil Ebrahimie, Elai Davicioni, Robert B. Jenkins, R. Jeffrey Karnes, Ashley E. Ross, Robert B. Den, Eric A. Klein, Kim N. Chi, Hayley S. Ramshaw, Elizabeth D. Williams, Amina Zoubeidi, Gregory J. Goodall, Felix Y. Feng, Lisa M. Butler, Wayne D. Tilley, Luke A. Selth
Journal: Cancer Research
Cancer Res (2017) 77 (4): 1021–1034.
DOI: https://doi.org/10.1158/0008-5472.CAN-16-2529
Published: 14 February 2017
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Includes: Supplementary data
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Abstract B39: Long noncoding RNA PCAT14/PRCAT104; A prognostic biomarker in prostate cancer

Rohit Malik, Xiang Zhang, Sudhanshu Shukla, Yashar Y. Niknafs, Shuang Zhao, Felix Y. Feng, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2016) 76 (6_Supplement): B39.
DOI: https://doi.org/10.1158/1538-7445.NONRNA15-B39
Published: 13 May 2016
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