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Felicitas Genze
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Journal Articles

HSP90 Supports Tumor Growth and Angiogenesis through PRKD2 Protein Stabilization

Ninel Azoitei, Kristina Diepold, Cornelia Brunner, Arefeh Rouhi, Felicitas Genze, Alexander Becher, Hans Kestler, Johan van Lint, Gabriela Chiosis, John Koren, III, Stefan Fröhling, Claudia Scholl, Thomas Seufferlein
Journal: Cancer Research
Cancer Res (2014) 74 (23): 7125–7136.
https://doi.org/10.1158/0008-5472.CAN-14-1017
Published: 30 November 2014
View article titled, HSP90 Supports Tumor Growth and Angiogenesis through PRKD2 Protein Stabilization
Open the PDF for HSP90 Supports Tumor Growth and Angiogenesis through PRKD2 Protein Stabilization in another window
Includes: Supplementary data
Journal Articles

Abstract 5129: Role of PRKD2 in HSP90 inhibition-mediated suppression of cancer growth

Ninel Azoitei, Kristina Diepold, Felicitas Genze, Arefeh Rouhi, Susanne Brobovich, Stefan Froehling, Gabriela Chiosis, Cornelia Brunner, Johan van Lint, Marcus Cronauer, Claudia Scholl, Thomas Seufferlein
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5129.
https://doi.org/10.1158/1538-7445.AM2014-5129
Published: 01 October 2014
View article titled, Abstract 5129: Role of PRKD2 in HSP90 inhibition-mediated suppression of cancer growth
Journal Articles

Abstract B59: IKK-mediated phosphorylation of the androgen receptor: A mechanism to modulate AR-cofactor interaction

Lasse Marck, Garima Jain, Marcus V. Cronauer, Felicitas Genze, Ralf Marienfeld
Journal: Cancer Research
Cancer Res (2013) 73 (13_Supplement): B59.
https://doi.org/10.1158/1538-7445.CEC13-B59
Published: 13 May 2014
View article titled, Abstract B59: IKK-mediated phosphorylation of the androgen receptor: A mechanism to modulate AR-cofactor interaction
Journal Articles

Abstract 2773: HSP90 inhibitors target KRAS mutant human tumors through degradation of STK33

Ninel Azoitei, Christopher M. Hoffmann, Jana M. Ellegast, Claudia R. Ball, Kerstin Obermayer, Ulrike Gößele, Britta Koch, Katrin Faber, Felicitas Genze, Mark Schrader, Hans A. Kestler, Hartmut Döhner, Gabriela Chiosis, Hanno Glimm, Stefan Fröhling, Claudia Scholl
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2773.
https://doi.org/10.1158/1538-7445.AM2012-2773
Published: 15 April 2012
View article titled, Abstract 2773: HSP90 inhibitors target KRAS mutant human tumors through degradation of STK33
Journal Articles

Small Molecule XIAP Inhibitors Enhance TRAIL-Induced Apoptosis and Antitumor Activity in Preclinical Models of Pancreatic Carcinoma

Meike Vogler, Henning Walczak, Dominic Stadel, Tobias L. Haas, Felicitas Genze, Marjana Jovanovic, Umesh Bhanot, Cornelia Hasel, Peter Möller, Jürgen E. Gschwend, Thomas Simmet, Klaus-Michael Debatin, Simone Fulda
Journal: Cancer Research
Cancer Res (2009) 69 (6): 2425–2434.
https://doi.org/10.1158/0008-5472.CAN-08-2436
Published: 17 March 2009
View article titled, Small Molecule XIAP Inhibitors Enhance TRAIL-Induced Apoptosis and Antitumor Activity in Preclinical Models of Pancreatic Carcinoma
Open the PDF for Small Molecule XIAP Inhibitors Enhance TRAIL-Induced Apoptosis and Antitumor Activity in Preclinical Models of Pancreatic Carcinoma in another window
Includes: Supplementary data
Journal Articles

Targeting XIAP Bypasses Bcl-2–Mediated Resistance to TRAIL and Cooperates with TRAIL to Suppress Pancreatic Cancer Growth In vitro and In vivo

Meike Vogler, Henning Walczak, Dominic Stadel, Tobias L. Haas, Felicitas Genze, Marjana Jovanovic, Jürgen E. Gschwend, Thomas Simmet, Klaus-Michael Debatin, Simone Fulda
Journal: Cancer Research
Cancer Res (2008) 68 (19): 7956–7965.
https://doi.org/10.1158/0008-5472.CAN-08-1296
Published: 30 September 2008
View article titled, Targeting XIAP Bypasses Bcl-2–Mediated Resistance to TRAIL and Cooperates with TRAIL to Suppress Pancreatic Cancer Growth <em>In vitro</em> and <em>In vivo</em>
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Includes: Supplementary data
Journal Articles

Sensitizer/inducer strategy of XIAP inhibitors combined with TRAIL: A new paradigm for apoptosis-based therapy of pancreatic cancer

Meike Vogler, Henning Walczak, Dominic Stadel, Tobias Haas, Felicitas Genze, Marjana Jovanovic, Umesh Bhanot, Cornelia Hasel, Peter Moeller, Juergen Gschwend, Thomas Simmet, Klaus-Michael Debatin, Simone Fulda
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2550.
Published: 01 May 2008
View article titled, Sensitizer/inducer strategy of XIAP inhibitors combined with TRAIL: A new paradigm for apoptosis-based therapy of pancreatic cancer
Journal Articles

Activation of Phosphatidylinositol 3-Kinase and Extracellular Signal-Regulated Kinase Is Required for Glial Cell Line-Derived Neurotrophic Factor-Induced Migration and Invasion of Pancreatic Carcinoma Cells

Christine Veit, Felicitas Genze, Andre Menke, Silke Hoeffert, Thomas M. Gress, Peter Gierschik, Klaudia Giehl
Journal: Cancer Research
Cancer Res (2004) 64 (15): 5291–5300.
https://doi.org/10.1158/0008-5472.CAN-04-1112
Published: 02 August 2004
View article titled, Activation of Phosphatidylinositol 3-Kinase and Extracellular Signal-Regulated Kinase Is Required for Glial Cell Line-Derived Neurotrophic Factor-Induced Migration and Invasion of Pancreatic Carcinoma Cells
Open the PDF for Activation of Phosphatidylinositol 3-Kinase and Extracellular Signal-Regulated Kinase Is Required for Glial Cell Line-Derived Neurotrophic Factor-Induced Migration and Invasion of Pancreatic Carcinoma Cells in another window