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Journal Articles

Abstract 28: A CRISPR/Cas9 screening platform ImmuT Finder® enables in vivo T cell functional screening and identification of potent immunoregulatory targets for next-generation T cell therapy

Jingwei Sun, Jiahui Jin, Jingman Wang, Yao Sheng, Fei Li, Lingyun Chen, Yongchao Tan, Zhao Xu, Yanbin Liu, Ke Liu, Yarong Liu
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 28.
https://doi.org/10.1158/1538-7445.AM2024-28
Published: 22 March 2024
View article titled, Abstract 28: A CRISPR/Cas9 screening platform ImmuT Finder® enables in vivo T cell functional screening and identification of potent immunoregulatory targets for next-generation T cell therapy
Journal Articles

Abstract 6348: Unveiling diverse trimeric forms of STEAP1 in human prostate cancer cells: Exploring STEAP1-STEAP2 interdependence for expression and plasma membrane localization

Cong Li, Lingming Liang, Joonhee Park, Olga Pryshchep, Binnaz Staley, Peng Li, Ben Alba, Xuan Liu, Fei Li, Gregory L. Moore, Matthew J. Bernett, Umesh Muchhal, John Desjarlais, Angela Coxon, Julie M. Bailis
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6348.
https://doi.org/10.1158/1538-7445.AM2024-6348
Published: 22 March 2024
View article titled, Abstract 6348: Unveiling diverse trimeric forms of STEAP1 in human prostate cancer cells: Exploring STEAP1-STEAP2 interdependence for expression and plasma membrane localization
Journal Articles

Abstract 4062: The discovery and development of a CRISPR/Cas9-engineered tumor-infiltrating lymphocytes product (GT316) as a next-generation TIL therapy

Yarong Liu, Jingwei Sun, Yao Sheng, Jingman Wang, Jiahui Jin, Fei Li, Lingyun Chen, Di Zhou, Yongchao Tan, Quanwei Wang, Zhao Xu, Haibao Li, Pin Wang, Jun Cui
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4062.
https://doi.org/10.1158/1538-7445.AM2023-4062
Published: 04 April 2023
View article titled, Abstract 4062: The discovery and development of a CRISPR/Cas9-engineered tumor-infiltrating lymphocytes product (GT316) as a next-generation TIL therapy
Journal Articles

Abstract C070: Investigation of the roles of BDKRB1 in pancreatic cancer progression and tumor microenvironment modulation

Ching-Fei Li, Jie Fu, Heng-Huan Lee, Ying-Nai Wang, Yu-Yi Chu, Paul J. Chiao, Mien-Chie Hung
Journal: Cancer Research
Cancer Res (2022) 82 (22_Supplement): C070.
https://doi.org/10.1158/1538-7445.PANCA22-C070
Published: 15 November 2022
View article titled, Abstract C070: Investigation of the roles of BDKRB1 in pancreatic cancer progression and tumor microenvironment modulation
Journal Articles

Abstract 1356: In vivo epigenetic CRISPR screen identifies PRMT5 as an immune suppressor in pancreatic cancer

Hai Hu, Jiehui Deng, Fei Li, wei wang, Alireza Khodadadi-Jamayran
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1356.
https://doi.org/10.1158/1538-7445.AM2022-1356
Published: 15 June 2022
View article titled, Abstract 1356: In vivo epigenetic CRISPR screen identifies PRMT5 as an immune suppressor in pancreatic cancer
Journal Articles

Abstract 5582: Modulation of intracellular kinase signaling to improve TIL manufacturing for adoptive cell therapy

Zixiao Shi, Sheng Yao, Peipei Zhao, Fei Li, Di Zhou, Jun Cui, Jingwei Sun, Yarong Liu
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5582.
https://doi.org/10.1158/1538-7445.AM2022-5582
Published: 15 June 2022
View article titled, Abstract 5582: Modulation of intracellular kinase signaling to improve TIL manufacturing for adoptive cell therapy
Journal Articles

Targeting HER2 Exon 20 Insertion–Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib

Han Han, Shuai Li, Ting Chen, Michael Fitzgerald, Shengwu Liu, Chengwei Peng, Kwan Ho Tang, Shougen Cao, Johara Chouitar, Jiansheng Wu, David Peng, Jiehui Deng, Zhendong Gao, Theresa E. Baker, Fei Li, Hua Zhang, Yuanwang Pan, Hailin Ding, Hai Hu, Val Pyon, Cassandra Thakurdin, Eleni Papadopoulos, Sittinon Tang, Francois Gonzalvez, Haiquan Chen, Victor M. Rivera, Rachael Brake, Sylvie Vincent, Kwok-Kin Wong
Journal: Cancer Research
Cancer Res (2021) 81 (20): 5311–5324.
https://doi.org/10.1158/0008-5472.CAN-21-1526
Published: 15 October 2021
View article titled, Targeting <em>HER2</em> Exon 20 Insertion–Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib
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Includes: Supplementary data
Journal Articles

Correction: YAP Suppresses Lung Squamous Cell Carcinoma Progression via Deregulation of the DNp63–GPX2 Axis and ROS Accumulation

Hsinyi Huang, Wenjing Zhang, Yafang Pan, Yijun Gao, Lei Deng, Fuming Li, Fei Li, Xueyan Ma, Shenda Hou, Jing Xu, Peixue Li, Xiaoxun Li, Guohong Hu, Cheng Li, Haiquan Chen, Lei Zhang, Hongbin Ji
Journal: Cancer Research
Cancer Res (2021) 81 (19): 5127.
https://doi.org/10.1158/0008-5472.CAN-21-2379
Published: 01 October 2021
View article titled, Correction: YAP Suppresses Lung Squamous Cell Carcinoma Progression via Deregulation of the DNp63–GPX2 Axis and ROS Accumulation
Open the PDF for Correction: YAP Suppresses Lung Squamous Cell Carcinoma Progression via Deregulation of the DNp63–GPX2 Axis and ROS Accumulation in another window
Journal Articles

BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency

Manav Gupta, Carla P. Concepcion, Caroline G. Fahey, Hasmik Keshishian, Arjun Bhutkar, Christine F. Brainson, Francisco J. Sanchez-Rivera, Patrizia Pessina, Jonathan Y. Kim, Antoine Simoneau, Margherita Paschini, Mary C. Beytagh, Caroline R. Stanclift, Monica Schenone, D.R. Mani, Chendi Li, Audris Oh, Fei Li, Hai Hu, Angeliki Karatza, Roderick T. Bronson, Alice T. Shaw, Aaron N. Hata, Kwok-Kin Wong, Lee Zou, Steven A. Carr, Tyler Jacks, Carla F. Kim
Journal: Cancer Research
Cancer Res (2020) 80 (18): 3841–3854.
https://doi.org/10.1158/0008-5472.CAN-20-1744
Published: 15 September 2020
View article titled, BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency
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Includes: Supplementary data
Journal Articles

Epigenetic CRISPR Screens Identify Npm1 as a Therapeutic Vulnerability in Non–Small Cell Lung Cancer

Fei Li, Wai-Lung Ng, Troy A. Luster, Hai Hu, Vladislav O. Sviderskiy, Catríona M. Dowling, Kate E.R. Hollinshead, Paula Zouitine, Hua Zhang, Qingyuan Huang, Michela Ranieri, Wei Wang, Zhaoyuan Fang, Ting Chen, Jiehui Deng, Kai Zhao, Hon-Cheong So, Alireza Khodadadi-Jamayran, Mousheng Xu, Angeliki Karatza, Val Pyon, Shuai Li, Yuanwang Pan, Kristen Labbe, Christina Almonte, John T. Poirier, George Miller, Richard Possemato, Jun Qi, Kwok-Kin Wong
Journal: Cancer Research
Cancer Res (2020) 80 (17): 3556–3567.
https://doi.org/10.1158/0008-5472.CAN-19-3782
Published: 02 September 2020
View article titled, Epigenetic CRISPR Screens Identify <em>Npm1</em> as a Therapeutic Vulnerability in Non–Small Cell Lung Cancer
Open the PDF for Epigenetic CRISPR Screens Identify <em>Npm1</em> as a Therapeutic Vulnerability in Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 2711: Mechanism of natural progression from low grade glioma to glioblastoma: A case report

Long Wang, Xuegang Li, Tunan Chen, Feilong Zhao, Tonghui Ma, Hua Feng, Fei Li
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2711.
https://doi.org/10.1158/1538-7445.AM2020-2711
Published: 15 August 2020
View article titled, Abstract 2711: Mechanism of natural progression from low grade glioma to glioblastoma: A case report
Journal Articles

Abstract 3223: Overcome LKB1 mutated cancer resistance to anti-PD1 treatment

Jiehui Deng, Aatish Thennavan, Yuanwang Pan, Igor Dolgalev, Ting Chen, Heather Silver, Matthew Harris, Val Pyon, Fei Li, Chelsea Lee, Aristotelis Tsirigos, Eli Rothenberg, Charles M. Perou, Kwok-Kin Wong
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3223.
https://doi.org/10.1158/1538-7445.AM2019-3223
Published: 01 July 2019
View article titled, Abstract 3223: Overcome LKB1 mutated cancer resistance to anti-PD1 treatment
Journal Articles

Abstract 4006: Effect of Prior Cancer on Trial Eligibility and Treatment Outcomes in Nasopharyngeal Carcinoma: Implications for Clinical Trial Accrual

Ya-Qin Wang, Jia-Wei Lv, Ling-Long Tang, Xiao-Jing Du, Lei Chen, Wen-Fei Li, Xu Liu, Ying Guo, Ai-Hua Lin, Yan-Ping Mao, Ying Sun, Yu-Pei Chen, Jun Ma
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4006.
https://doi.org/10.1158/1538-7445.AM2019-4006
Published: 01 July 2019
View article titled, Abstract 4006: Effect of Prior Cancer on Trial Eligibility and Treatment Outcomes in Nasopharyngeal Carcinoma: Implications for Clinical Trial Accrual
Journal Articles

NK Cells Mediate Synergistic Antitumor Effects of Combined Inhibition of HDAC6 and BET in a SCLC Preclinical Model

Yan Liu, Yuyang Li, Shengwu Liu, Dennis O. Adeegbe, Camilla L. Christensen, Max M. Quinn, Ruben Dries, Shiwei Han, Kevin Buczkowski, Xiaoen Wang, Ting Chen, Peng Gao, Hua Zhang, Fei Li, Peter S. Hammerman, James E. Bradner, Steven N. Quayle, Kwok-Kin Wong
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (13): 3709–3717.
https://doi.org/10.1158/0008-5472.CAN-18-0161
Published: 01 July 2018
View article titled, NK Cells Mediate Synergistic Antitumor Effects of Combined Inhibition of HDAC6 and BET in a SCLC Preclinical Model
Open the PDF for NK Cells Mediate Synergistic Antitumor Effects of Combined Inhibition of HDAC6 and BET in a SCLC Preclinical Model in another window
Includes: Supplementary data
Journal Articles

YAP Suppresses Lung Squamous Cell Carcinoma Progression via Deregulation of the DNp63–GPX2 Axis and ROS Accumulation

Hsinyi Huang, Wenjing Zhang, Yafang Pan, Yijun Gao, Lei Deng, Fuming Li, Fei Li, Xueyan Ma, Shenda Hou, Jing Xu, Peixue Li, Xiaoxun Li, Guohong Hu, Cheng Li, Haiquan Chen, Lei Zhang, Hongbin Ji
Journal: Cancer Research
Cancer Res (2017) 77 (21): 5769–5781.
https://doi.org/10.1158/0008-5472.CAN-17-0449
Published: 31 October 2017
View article titled, YAP Suppresses Lung Squamous Cell Carcinoma Progression via Deregulation of the DNp63–GPX2 Axis and ROS Accumulation
Open the PDF for YAP Suppresses Lung Squamous Cell Carcinoma Progression via Deregulation of the DNp63–GPX2 Axis and ROS Accumulation in another window
Includes: Supplementary data
Journal Articles

Gemcitabine and Chk1 Inhibitor AZD7762 Synergistically Suppress the Growth of Lkb1-Deficient Lung Adenocarcinoma

Yan Liu, Yuyang Li, Xiaoen Wang, Feiyang Liu, Peng Gao, Max M. Quinn, Fei Li, Ashley A. Merlino, Cyril Benes, Qingsong Liu, Nathanael S. Gray, Kwok-Kin Wong
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (18): 5068–5076.
https://doi.org/10.1158/0008-5472.CAN-17-0567
Published: 14 September 2017
View article titled, Gemcitabine and Chk1 Inhibitor AZD7762 Synergistically Suppress the Growth of Lkb1-Deficient Lung Adenocarcinoma
Open the PDF for Gemcitabine and Chk1 Inhibitor AZD7762 Synergistically Suppress the Growth of Lkb1-Deficient Lung Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 348: LKB1 deficiency confers lung adenocarcinoma phenotypic plasticity with squamous transdifferentiation potential.

Xiangkun Han, Fuming Li, Zhaoyuan Fang, Yijun Gao, Rong Fang, Fei Li, Yihua Sun, Jufeng Xia, Shun Yao, Li Li, Haiquan Chen, Yingyong Hou, Xinyuan Liu, Hongbin Ji
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 348.
https://doi.org/10.1158/1538-7445.AM2013-348
Published: 15 April 2013
View article titled, Abstract 348: LKB1 deficiency confers lung adenocarcinoma phenotypic plasticity with squamous transdifferentiation potential.
Journal Articles

Abstract 4433: DW-MR imaging as a predictive biomarker of radiosensitization of GBM through targeted inhibition of checkpoint kinases.

Terence Williams, Stefanie Galbán, Fei Li, Kevin Heist, Craig Galbán, Theodore S. Lawrence, Eric C. Holland, Tami Thomae, Thomas Chenevert, Alnawaz Rehemtulla, Brian D. Ross
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4433.
https://doi.org/10.1158/1538-7445.AM2013-4433
Published: 15 April 2013
View article titled, Abstract 4433: DW-MR imaging as a predictive biomarker of radiosensitization of GBM through targeted inhibition of checkpoint kinases.
Journal Articles

The CRTC1-NEDD9 Signaling Axis Mediates Lung Cancer Progression Caused by LKB1 Loss

Yan Feng, Ye Wang, Zuoyun Wang, Zhaoyuan Fang, Fei Li, Yijun Gao, Hongyan Liu, Tian Xiao, Fuming Li, Yang Zhou, Qiwei Zhai, Xiaolong Liu, Yihua Sun, Nabeel Bardeesy, Kwok-kin Wong, Haiquan Chen, Zhi-qi Xiong, Hongbin Ji
Journal: Cancer Research
Cancer Res (2012) 72 (24): 6502–6511.
https://doi.org/10.1158/0008-5472.CAN-12-1909
Published: 16 December 2012
View article titled, The CRTC1-NEDD9 Signaling Axis Mediates Lung Cancer Progression Caused by <em>LKB1</em> Loss
Open the PDF for The CRTC1-NEDD9 Signaling Axis Mediates Lung Cancer Progression Caused by <em>LKB1</em> Loss in another window
Includes: Supplementary data
Journal Articles

Abstract 2355: Assessment of glioma recurrence following radiotherapy using the parametric response map: A preclinical study

Benjamin Lemasson, Stefanie Galbán, Fei Li, Kevin A. Heist, Judith Sebolt-Leopold, Alnawez Rehemtulla, Thomas Chenevert, Craig Galbán, Brian D. Ross
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2355.
https://doi.org/10.1158/1538-7445.AM2012-2355
Published: 15 April 2012
View article titled, Abstract 2355: Assessment of glioma recurrence following radiotherapy using the parametric response map: A preclinical study