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Journal Articles

Abstract 2333: Modulation of Bax and mTOR for cancer therapeutics

Cancer Res (2017) 77 (13_Supplement): 2333.

https://doi.org/10.1158/1538-7445.AM2017-2333

Published: 01 July 2017

View article titled, Abstract 2333: Modulation of Bax and mTOR for cancer therapeutics

Journal Articles

Abstract 2922: Development of Bcl2 BH4 antagonist for cancer therapy

Bingshe Han, Dongkyoo Park, Rui Li, Maohua Xie, Taofeek Owonikoko, Gabriel Sica, Chunyong Ding, Jia Zhou, Andrew Magis, Suresh Ramalingam, Fadlo Khuri, Walter Curran, Xingming Deng

Cancer Res (2015) 75 (15_Supplement): 2922.

https://doi.org/10.1158/1538-7445.AM2015-2922

Published: 01 August 2015

View article titled, Abstract 2922: Development of Bcl2 BH4 antagonist for cancer therapy

Journal Articles

Abstract 3046: Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth

Lingtao Jin, Dan Li, Gina Alesi, Jun Fan, Hee-Bum Kang, Lu Zhou, Titus Boggon, Kelly Magliocca, Chuan He, Martha Arellano, Hanna Khoury, Dong Shin, Fadlo Khuri, Sumin Kang

Cancer Res (2015) 75 (15_Supplement): 3046.

https://doi.org/10.1158/1538-7445.AM2015-3046

Published: 01 August 2015

View article titled, Abstract 3046: Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth

Journal Articles

Abstract 773: Restoration of LKB1 defect in EKVX cells leads to resistance to microtubule targeting agents

Kaisheng Mao, Fakeng Liu, Xiuju Liu, Yulong He, Fadlo Khuri, Adam Marcus, Mingsong Li, Wei Zhou

Cancer Res (2014) 74 (19_Supplement): 773.

https://doi.org/10.1158/1538-7445.AM2014-773

Published: 01 October 2014

View article titled, Abstract 773: Restoration of LKB1 defect in EKVX cells leads to resistance to microtubule targeting agents

Journal Articles

Abstract 3154: RSK2-mediated phosphorylation of stathmin promotes microtubule polymerization, providing a pro-invasive advantage to metastatic cancer cells

Gina Alesi, Dan Li, Lingtao Jin, Georgia Z. Chen, Dong M. Shin, Fadlo Khuri, Sumin Kang

Cancer Res (2014) 74 (19_Supplement): 3154.

https://doi.org/10.1158/1538-7445.AM2014-3154

Published: 01 October 2014

View article titled, Abstract 3154: RSK2-mediated phosphorylation of stathmin promotes microtubule polymerization, providing a pro-invasive advantage to metastatic cancer cells

Journal Articles

Abstract 1975: AICAR induces cell death in LKB1-deficient NSCLC.

Fakeng Liu, Wei Zhou, Xiuju Liu, Shi-yong Sun, Fadlo Khuri, Yu-long He, Diansheng Zhong

Cancer Res (2013) 73 (8_Supplement): 1975.

https://doi.org/10.1158/1538-7445.AM2013-1975

Published: 15 April 2013

View article titled, Abstract 1975: AICAR induces cell death in LKB1-deficient NSCLC.

Journal Articles

Abstract 1011: NNK promotes migration and invasion of cancer cells through activation of c-Src, PKCι and FAK loop

Jie Shen, Lijun Xu, Shi-Yong Sun, Fadlo Khuri, Xingming Deng

Cancer Res (2011) 71 (8_Supplement): 1011.

https://doi.org/10.1158/1538-7445.AM2011-1011

Published: 15 April 2011

View article titled, Abstract 1011: NNK promotes migration and invasion of cancer cells through activation of c-Src, PKCι and FAK loop

Journal Articles

Abstract 2567: Preclinical evaluation of Poly (ADP) Ribose Polymerase (PARP) enzyme inhibitor, ABT-888, in combination with cytotoxic agents in small cell lung cancer (SCLC)

Taofeek K. Owonikoko, Guojing Zhang, Ping Yue, Suresh Ramalingam, Fadlo Khuri, Shi-Yong Sun

Cancer Res (2011) 71 (8_Supplement): 2567.

https://doi.org/10.1158/1538-7445.AM2011-2567

Published: 15 April 2011

View article titled, Abstract 2567: Preclinical evaluation of Poly (ADP) Ribose Polymerase (PARP) enzyme inhibitor, ABT-888, in combination with cytotoxic agents in small cell lung cancer (SCLC)

Journal Articles

Abstract 1201: Inhibition of ASK1 through phosphorylation of serine 967 by PI3K/Akt-mediated pathways

Mary C. Puckett, Erinn Goldman, Lisa Cockrell, Fadlo Khuri, Haian Fu

Cancer Res (2010) 70 (8_Supplement): 1201.

https://doi.org/10.1158/1538-7445.AM10-1201

Published: 15 April 2010

View article titled, Abstract 1201: Inhibition of ASK1 through phosphorylation of serine 967 by PI3K/Akt-mediated pathways

Journal Articles

Abstract 34: Oncogenic tyrosine kinases phosphorylate and inhibit PKM2 to provide a metabolic advantage to tumor growth

Taro Hitosugi, Sumin Kang, Matthew G. Vander Heiden, Tae-Wook Chung, Sagar Lonial, Xu Wang, Georgia Z. Chen, Jianxin Xie, Ting-Lei Gu, Roberto D. Polakiewicz, Johannes L. Roesel, Titus Boggon, Fadlo Khuri, D. Gary Gilliland, Lewis C. Cantley, Jonathan Kaufman, Jing Chen

Cancer Res (2010) 70 (8_Supplement): 34.

https://doi.org/10.1158/1538-7445.AM10-34

Published: 15 April 2010

View article titled, Abstract 34: Oncogenic tyrosine kinases phosphorylate and inhibit PKM2 to provide a metabolic advantage to tumor growth

Journal Articles

Abstract #33: In vitro and in vivo synergistic anti-tumor efficacy of two naturally available dietary polyphenols EGCG and luteolin

Arm Amin, Dongsheng Wang, Fadlo Khuri, Zhuo Chen, Dong Shin

Cancer Res (2009) 69 (9_Supplement): 33.

Published: 01 May 2009

View article titled, Abstract #33: In vitro and in vivo synergistic anti-tumor efficacy of two naturally available dietary polyphenols EGCG and luteolin

Journal Articles

Abstract #2449: Web-based head and neck cancer tissue database

Haibin Wang, Anna Kuehn, Erik Bouzyk, Susan Muller, Fadlo Khuri, Dong Shin, Mourad Tighiouart

Cancer Res (2009) 69 (9_Supplement): 2449.

Published: 01 May 2009

View article titled, Abstract #2449: Web-based head and neck cancer tissue database

Journal Articles

Abstract #1055: Development of a quantum dots (QDs)-based quantification method for multiplexed biomarkers in prediction of metastasis

Dong-hai Huang, Clifford Hoyt, Xiang-hong Peng, Dongsheng Wang, Hongzheng Zhang, Fadlo Khuri, Dong Shin, Zhuo Chen

Cancer Res (2009) 69 (9_Supplement): 1055.

Published: 01 May 2009

View article titled, Abstract #1055: Development of a quantum dots (QDs)-based quantification method for multiplexed biomarkers in prediction of metastasis

Journal Articles

Abstract #941: Synergistic growth inhibition of squamous cell carcinoma of the head and neck by Erlotinib and EGCG: the role of p53-dependent inhibition of nuclear factor-\#922;B

ARM Amin, Xin Zhang, Fadlo Khuri, Zhuo Chen, Dong Shin

Cancer Res (2009) 69 (9_Supplement): 941.

Published: 01 May 2009

View article titled, Abstract #941: Synergistic growth inhibition of squamous cell carcinoma of the head and neck by Erlotinib and EGCG: the role of p53-dependent inhibition of nuclear factor-\#922;B

Journal Articles

Abstract #2700: Anticancer activity profiling of a panel of curcumin analogues in head and neck and lung cancer cells

Bin lou, Yuhong Du, Andrea Kasinski, Shala Thomas, Aiming Sun, Shi-Yong Sun, Georgia Chen, Dong Shin, Fadlo Khuri, Dennis Liotta, James Snyder, Haian Fu

Cancer Res (2009) 69 (9_Supplement): 2700.

Published: 01 May 2009

View article titled, Abstract #2700: Anticancer activity profiling of a panel of curcumin analogues in head and neck and lung cancer cells

Journal Articles

Abstract #4461: Regulation of the tumor suppressor Cables1 by Akt/PKB-induced 14-3-3 interaction

Zhi Shi, Hae Ryon Park, Zijiang Li, Cheryl Ho, Fadlo Khuri, Haian Fu

Cancer Res (2009) 69 (9_Supplement): 4461.

Published: 01 May 2009

View article titled, Abstract #4461: Regulation of the tumor suppressor Cables1 by Akt/PKB-induced 14-3-3 interaction

Journal Articles

Abstract #1848: Effect of the protein Farnesyltransferase expression on HDAC6 activity and cellular sensitivity to taxane treatment

Chantal Chanel-Vos, Ada Gjyrezi, John Kauh, Fadlo Khuri, Paraskevi Giannakakou

Cancer Res (2009) 69 (9_Supplement): 1848.

Published: 01 May 2009

View article titled, Abstract #1848: Effect of the protein Farnesyltransferase expression on HDAC6 activity and cellular sensitivity to taxane treatment

Journal Articles

Abstract #5132: The eIF4E/eIF4G interaction inhibitor 4EGI-1 augments TRAIL-induced apoptosis through DR5 induction and c-FLIP downregulation independent of inhibition of cap-dependent protein translation

Songqing Fan, Yikun Li, Ping Yue, Fadlo Khuri, Shi-Yong Sun

Cancer Res (2009) 69 (9_Supplement): 5132.

Published: 01 May 2009

View article titled, Abstract #5132: The eIF4E/eIF4G interaction inhibitor 4EGI-1 augments TRAIL-induced apoptosis through DR5 induction and c-FLIP downregulation independent of inhibition of cap-dependent protein translation

Journal Articles

Abstract #5348: Protein phosphatase 2A negatively regulates eukaryotic initiation factor 4E (eIF4E) phosphorylation and eIF4F activity

Yikun Li, Xuerong Wang, Fadlo Khuri, Shi-Yong Sun

Cancer Res (2009) 69 (9_Supplement): 5348.

Published: 01 May 2009

View article titled, Abstract #5348: Protein phosphatase 2A negatively regulates eukaryotic initiation factor 4E (eIF4E) phosphorylation and eIF4F activity

Journal Articles

Abstract #5239: Erlotinib enhances RAD001\#8217;s anticancer activity in vivo involving abrogation of mTOR inhibition-induced eIF4E phosphorylation

Songqing Fan, Xuerong Wang, Ping Yue, John Kauh, Suresh Ramalingam, Fadlo Khuri, Shi-Yong Sun

Cancer Res (2009) 69 (9_Supplement): 5239.

Published: 01 May 2009

View article titled, Abstract #5239: Erlotinib enhances RAD001\#8217;s anticancer activity in vivo involving abrogation of mTOR inhibition-induced eIF4E phosphorylation

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Abstract 2333: Modulation of Bax and mTOR for cancer therapeutics

Abstract 2922: Development of Bcl2 BH4 antagonist for cancer therapy

Abstract 3046: Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth

Abstract 773: Restoration of LKB1 defect in EKVX cells leads to resistance to microtubule targeting agents

Abstract 3154: RSK2-mediated phosphorylation of stathmin promotes microtubule polymerization, providing a pro-invasive advantage to metastatic cancer cells

Abstract 1975: AICAR induces cell death in LKB1-deficient NSCLC.

Abstract 1011: NNK promotes migration and invasion of cancer cells through activation of c-Src, PKCι and FAK loop

Abstract 2567: Preclinical evaluation of Poly (ADP) Ribose Polymerase (PARP) enzyme inhibitor, ABT-888, in combination with cytotoxic agents in small cell lung cancer (SCLC)

Abstract 1201: Inhibition of ASK1 through phosphorylation of serine 967 by PI3K/Akt-mediated pathways

Abstract 34: Oncogenic tyrosine kinases phosphorylate and inhibit PKM2 to provide a metabolic advantage to tumor growth

Abstract #33: In vitro and in vivo synergistic anti-tumor efficacy of two naturally available dietary polyphenols EGCG and luteolin

Abstract #2449: Web-based head and neck cancer tissue database

Abstract #1055: Development of a quantum dots (QDs)-based quantification method for multiplexed biomarkers in prediction of metastasis

Abstract #941: Synergistic growth inhibition of squamous cell carcinoma of the head and neck by Erlotinib and EGCG: the role of p53-dependent inhibition of nuclear factor-\#922;B

Abstract #2700: Anticancer activity profiling of a panel of curcumin analogues in head and neck and lung cancer cells

Abstract #4461: Regulation of the tumor suppressor Cables1 by Akt/PKB-induced 14-3-3 interaction

Abstract #1848: Effect of the protein Farnesyltransferase expression on HDAC6 activity and cellular sensitivity to taxane treatment

Abstract #5132: The eIF4E/eIF4G interaction inhibitor 4EGI-1 augments TRAIL-induced apoptosis through DR5 induction and c-FLIP downregulation independent of inhibition of cap-dependent protein translation

Abstract #5348: Protein phosphatase 2A negatively regulates eukaryotic initiation factor 4E (eIF4E) phosphorylation and eIF4F activity

Abstract #5239: Erlotinib enhances RAD001\#8217;s anticancer activity in vivo involving abrogation of mTOR inhibition-induced eIF4E phosphorylation

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