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Journal Articles

Abstract 2333: Modulation of Bax and mTOR for cancer therapeutics

Rui Li, Chunyong Ding, Jun Zhang, Maohua Xie, Dongkyoo Park, Ye Ding, Guo Chen, Guojing Zhang, Melissa Gilbert-Ross, Wei Zhou, Adam Marcus, Shi-Yong Sun, Zhuo Chen, Gabriel Sica, Suresh Ramalingam, Andrew Magis, Haian Fu, Fadlo Khuri, Walter Curran, Taofeek Owonikoko, Dong Shin, Jia Zhou, Xingming Deng
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2333.
DOI: https://doi.org/10.1158/1538-7445.AM2017-2333
Published: 01 July 2017
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Journal Articles

Abstract 2922: Development of Bcl2 BH4 antagonist for cancer therapy

Bingshe Han, Dongkyoo Park, Rui Li, Maohua Xie, Taofeek Owonikoko, Gabriel Sica, Chunyong Ding, Jia Zhou, Andrew Magis, Suresh Ramalingam, Fadlo Khuri, Walter Curran, Xingming Deng
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2922.
DOI: https://doi.org/10.1158/1538-7445.AM2015-2922
Published: 01 August 2015
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Journal Articles

Abstract 3046: Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth

Lingtao Jin, Dan Li, Gina Alesi, Jun Fan, Hee-Bum Kang, Lu Zhou, Titus Boggon, Kelly Magliocca, Chuan He, Martha Arellano, Hanna Khoury, Dong Shin, Fadlo Khuri, Sumin Kang
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3046.
DOI: https://doi.org/10.1158/1538-7445.AM2015-3046
Published: 01 August 2015
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Journal Articles

Abstract 3154: RSK2-mediated phosphorylation of stathmin promotes microtubule polymerization, providing a pro-invasive advantage to metastatic cancer cells

Gina Alesi, Dan Li, Lingtao Jin, Georgia Z. Chen, Dong M. Shin, Fadlo Khuri, Sumin Kang
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3154.
DOI: https://doi.org/10.1158/1538-7445.AM2014-3154
Published: 01 October 2014
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Journal Articles

Abstract 773: Restoration of LKB1 defect in EKVX cells leads to resistance to microtubule targeting agents

Kaisheng Mao, Fakeng Liu, Xiuju Liu, Yulong He, Fadlo Khuri, Adam Marcus, Mingsong Li, Wei Zhou
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 773.
DOI: https://doi.org/10.1158/1538-7445.AM2014-773
Published: 01 October 2014
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Journal Articles

Abstract 1975: AICAR induces cell death in LKB1-deficient NSCLC.

Fakeng Liu, Wei Zhou, Xiuju Liu, Shi-yong Sun, Fadlo Khuri, Yu-long He, Diansheng Zhong
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1975.
DOI: https://doi.org/10.1158/1538-7445.AM2013-1975
Published: 15 April 2013
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Journal Articles

Abstract 1011: NNK promotes migration and invasion of cancer cells through activation of c-Src, PKCι and FAK loop

Jie Shen, Lijun Xu, Shi-Yong Sun, Fadlo Khuri, Xingming Deng
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1011.
DOI: https://doi.org/10.1158/1538-7445.AM2011-1011
Published: 15 April 2011
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Journal Articles

Abstract 2567: Preclinical evaluation of Poly (ADP) Ribose Polymerase (PARP) enzyme inhibitor, ABT-888, in combination with cytotoxic agents in small cell lung cancer (SCLC)

Taofeek K. Owonikoko, Guojing Zhang, Ping Yue, Suresh Ramalingam, Fadlo Khuri, Shi-Yong Sun
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2567.
DOI: https://doi.org/10.1158/1538-7445.AM2011-2567
Published: 15 April 2011
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Journal Articles

Abstract 1201: Inhibition of ASK1 through phosphorylation of serine 967 by PI3K/Akt-mediated pathways

Mary C. Puckett, Erinn Goldman, Lisa Cockrell, Fadlo Khuri, Haian Fu
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1201.
DOI: https://doi.org/10.1158/1538-7445.AM10-1201
Published: 15 April 2010
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Journal Articles

Abstract 34: Oncogenic tyrosine kinases phosphorylate and inhibit PKM2 to provide a metabolic advantage to tumor growth

Taro Hitosugi, Sumin Kang, Matthew G. Vander Heiden, Tae-Wook Chung, Sagar Lonial, Xu Wang, Georgia Z. Chen, Jianxin Xie, Ting-Lei Gu, Roberto D. Polakiewicz, Johannes L. Roesel, Titus Boggon, Fadlo Khuri, D. Gary Gilliland, Lewis C. Cantley, Jonathan Kaufman, Jing Chen
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 34.
DOI: https://doi.org/10.1158/1538-7445.AM10-34
Published: 15 April 2010
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Journal Articles

Abstract #2700: Anticancer activity profiling of a panel of curcumin analogues in head and neck and lung cancer cells

Bin lou, Yuhong Du, Andrea Kasinski, Shala Thomas, Aiming Sun, Shi-Yong Sun, Georgia Chen, Dong Shin, Fadlo Khuri, Dennis Liotta, James Snyder, Haian Fu
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2700.
Published: 01 May 2009
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Journal Articles

Abstract #5132: The eIF4E/eIF4G interaction inhibitor 4EGI-1 augments TRAIL-induced apoptosis through DR5 induction and c-FLIP downregulation independent of inhibition of cap-dependent protein translation

Songqing Fan, Yikun Li, Ping Yue, Fadlo Khuri, Shi-Yong Sun
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 5132.
Published: 01 May 2009
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Journal Articles

Abstract #5348: Protein phosphatase 2A negatively regulates eukaryotic initiation factor 4E (eIF4E) phosphorylation and eIF4F activity

Yikun Li, Xuerong Wang, Fadlo Khuri, Shi-Yong Sun
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 5348.
Published: 01 May 2009
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Journal Articles

Abstract #2449: Web-based head and neck cancer tissue database

Haibin Wang, Anna Kuehn, Erik Bouzyk, Susan Muller, Fadlo Khuri, Dong Shin, Mourad Tighiouart
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2449.
Published: 01 May 2009
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Journal Articles

Abstract #1055: Development of a quantum dots (QDs)-based quantification method for multiplexed biomarkers in prediction of metastasis

Dong-hai Huang, Clifford Hoyt, Xiang-hong Peng, Dongsheng Wang, Hongzheng Zhang, Fadlo Khuri, Dong Shin, Zhuo Chen
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1055.
Published: 01 May 2009
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Journal Articles

Abstract #941: Synergistic growth inhibition of squamous cell carcinoma of the head and neck by Erlotinib and EGCG: the role of p53-dependent inhibition of nuclear factor-\#922;B

ARM Amin, Xin Zhang, Fadlo Khuri, Zhuo Chen, Dong Shin
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 941.
Published: 01 May 2009
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Journal Articles

Abstract #33: In vitro and in vivo synergistic anti-tumor efficacy of two naturally available dietary polyphenols EGCG and luteolin

Arm Amin, Dongsheng Wang, Fadlo Khuri, Zhuo Chen, Dong Shin
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 33.
Published: 01 May 2009
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Journal Articles

Abstract #5239: Erlotinib enhances RAD001\#8217;s anticancer activity in vivo involving abrogation of mTOR inhibition-induced eIF4E phosphorylation

Songqing Fan, Xuerong Wang, Ping Yue, John Kauh, Suresh Ramalingam, Fadlo Khuri, Shi-Yong Sun
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 5239.
Published: 01 May 2009
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Journal Articles

Abstract #4461: Regulation of the tumor suppressor Cables1 by Akt/PKB-induced 14-3-3 interaction

Zhi Shi, Hae Ryon Park, Zijiang Li, Cheryl Ho, Fadlo Khuri, Haian Fu
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4461.
Published: 01 May 2009
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Journal Articles

Abstract #1848: Effect of the protein Farnesyltransferase expression on HDAC6 activity and cellular sensitivity to taxane treatment

Chantal Chanel-Vos, Ada Gjyrezi, John Kauh, Fadlo Khuri, Paraskevi Giannakakou
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1848.
Published: 01 May 2009
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