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Journal Articles

Abstract 5648: Response and resistance to CDK2 and CDK4/6 inhibition in GIST

Inga-Marie Schaefer, Meijun Z. Lundberg, Matthew L. Hemming, Sinem K. Saka, Matthew P. Serrata, Isabel Goldaracena, Ninning Liu, Peng Yin, Joao A. Paulo, Steven Gygi, George D. Demetri, Ewa Sicinska, Adrian Mariño-Enríquez, Jason L. Hornick, Chandrajit P. Raut, Wen-Bin Ou, Jonathan A. Fletcher

Cancer Res (2022) 82 (12_Supplement): 5648.

DOI: https://doi.org/10.1158/1538-7445.AM2022-5648

Published: 15 June 2022

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Journal Articles

Abstract 960: RNF43 G659fs is an oncogenic mutation in colorectal cancer and sensitizes tumor cells to PI3K/mTOR inhibition

Lishan Fang, Dane Ford-Roshon, Max Russo, Casey O'Brien, Carino Gurjao, Maximilien Grandclaudon, Steven M. Corsello, Srivatsan Raghavan, Namrata Udeshi, James Berstler, Ewa Sicinska, Kimmie Ng, Marios Giannakis

Cancer Res (2021) 81 (13_Supplement): 960.

DOI: https://doi.org/10.1158/1538-7445.AM2021-960

Published: 01 July 2021

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Journal Articles

Abstract 260: Identifying cancer drug sensitivity using live cell imaging dynamic BH3 profiling of solid tumor core biopsies

Rebecca German, Elizaveta Lavrova, Timothy Hagan, Otari Chipashvili, Ewa Sicinska, James Cleary, Kimmie Ng, Anthony Letai, Patrick Bhola

Cancer Res (2019) 79 (13_Supplement): 260.

DOI: https://doi.org/10.1158/1538-7445.AM2019-260

Published: 01 July 2019

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Journal Articles

Abstract 4478: High-throughput dynamic BH3 profiling identifies active cancer therapies in solid tumors

Patrick D. Bhola, Eman Ahmed, Jennifer Guerriero, Ewa Sicinska, Emily Su, Jing Ni, Elizaveta Lavrova, Otari Chipashvili, Timothy Hagan, Kimmie Ng, Andrew Aguirre, Jochen Lorch, Suzanne George, George Demetri, Jean Zhao, Anthony Letai

Cancer Res (2019) 79 (13_Supplement): 4478.

DOI: https://doi.org/10.1158/1538-7445.AM2019-4478

Published: 01 July 2019

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Journal Articles

Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and Are Targetable by BET Bromodomain Inhibition

Matthew L. Hemming, Matthew A. Lawlor, Jessica L. Andersen, Timothy Hagan, Otari Chipashvili, Thomas G. Scott, Chandrajit P. Raut, Ewa Sicinska, Scott A. Armstrong, George D. Demetri, James E. Bradner

Cancer Res (2019) 79 (5): 994–1009.

DOI: https://doi.org/10.1158/0008-5472.CAN-18-1888

Published: 01 March 2019

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Includes: Supplementary data

Journal Articles

Abstract 5129: Fusobacterium and co-occurring microbes in primary and metastatic colorectal cancer

Susan Bullman, Chandra S. Pedamallu, Ewa Sicinska, Thomas Clancy, Shuji Ogino, Josep Tabernero, Charles Fuchs, William C. Hahn, Paolo Nuciforo, Matthew Meyerson

Cancer Res (2018) 78 (13_Supplement): 5129.

DOI: https://doi.org/10.1158/1538-7445.AM2018-5129

Published: 01 July 2018

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Journal Articles

Abstract 5161: Inhibition of TBK1/IKBKE impacts tumor growth of KRAS-mutant colorectal cancers

Susanna Stinson, Jianhua He, Zhiheng Jia, Katie S. Walker, Zhi-Hua Cui, Joshua A. Kaplan, Chandrasekar Venkataramani, Yujin Wang, Fatima Guevara, Timothy Nelson, Ewa Sicinska, Kimmie Ng, Charles S. Fuchs, David Dornan

Cancer Res (2017) 77 (13_Supplement): 5161.

DOI: https://doi.org/10.1158/1538-7445.AM2017-5161

Published: 01 July 2017

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Journal Articles

Abstract 1759: Preclinical activity of selinexor, an inhibitor of XPO1/CRM1, in sarcoma

Robert Nakayama, Yi-Xiang Zhang, Alex Anatone, Ewa Sicinska, George Demetri, Andrew Wagner

Cancer Res (2015) 75 (15_Supplement): 1759.

DOI: https://doi.org/10.1158/1538-7445.AM2015-1759

Published: 01 August 2015

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Journal Articles

Abstract 607: Genomic analyses and novel models validate CDK4 as a therapeutic target in imatinib-resistant dermatofibrosarcoma protuberans

Adrian Marino-Enriquez, Grant Eilers, Jeffrey Czaplinski, Mark Mayeda, Derrick Tao, Meijun Zhu, Jason L. Hornick, Ewa Sicinska, Andrew J. Wagner, Jonathan A. Fletcher

Cancer Res (2015) 75 (15_Supplement): 607.

DOI: https://doi.org/10.1158/1538-7445.AM2015-607

Published: 01 August 2015

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Journal Articles

Abstract 3810: Selinexor (KPT-330), a novel selective inhibitor of nuclear export (SINE), shows single agent efficacy against alveolar soft part sarcoma (ASPS) in vivo

Marsha L. Crochiere, Trinayan Kashyap, Boris Klebanov, William Senapedis, Diego del Alamo, Sharon Tamir, Erkan Baloglu, Dilara McCauley, Robert Carlson, Michael Kauffman, Sharon Shacham, George Demetri, Andrew Wagner, Ewa Sicinska, Prafulla Gokhale, Nancy Kohl, Amy Saur, Yosef Landesman

Cancer Res (2014) 74 (19_Supplement): 3810.

DOI: https://doi.org/10.1158/1538-7445.AM2014-3810

Published: 01 October 2014

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Journal Articles

Abstract 168: Understanding the role of the carcinoid associated fibroblasts in the neuroendocrine tumor microenvironment

Michaela Bowden, Ewa Sicinska, Matthew Kulke, Massimo Loda

Cancer Res (2014) 74 (19_Supplement): 168.

DOI: https://doi.org/10.1158/1538-7445.AM2014-168

Published: 01 October 2014

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Journal Articles

Abstract LB-270: Genomic amplification of c-Jun activates genes that promote proliferation and cell migration in liposarcoma

Stefano Sioletic, Ewa Sicinska, Massimo Loda, Christopher D.M. Fletcher, Jonathan A. Fletcher, George D. Demetri, Eric L. Snyder

Cancer Res (2012) 72 (8_Supplement): LB-270.

DOI: https://doi.org/10.1158/1538-7445.AM2012-LB-270

Published: 15 April 2012

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Journal Articles

Abstract 4197: Mouse xenograft models of human soft tissue sarcomas

Ewa Sicinska, Samuel Moss, Joseph Brito, Carmen Priolo, Stephen Finn, Andrew Wagner, George Demetri, Massimo Loda

Cancer Res (2010) 70 (8_Supplement): 4197.

DOI: https://doi.org/10.1158/1538-7445.AM10-4197

Published: 15 April 2010

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Journal Articles

Abstract #LB-188: Unraveling the prostate cancer metabolome: Diagnostic and therapeutic implications

Carmen Priolo, Giorgia Zadra, Emanuele Palescandolo, Ewa Sicinska, Massimo Loda

Cancer Res (2009) 69 (9_Supplement): LB-188.

Published: 01 May 2009

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Journal Articles

The Isopeptidase USP2a Protects Human Prostate Cancer from Apoptosis

Carmen Priolo, Dan Tang, Mohan Brahamandan, Barbara Benassi, Ewa Sicinska, Shuji Ogino, Antonella Farsetti, Alessandro Porrello, Stephen Finn, Johann Zimmermann, Phillip Febbo, Massimo Loda

Cancer Res (2006) 66 (17): 8625–8632.

DOI: https://doi.org/10.1158/0008-5472.CAN-06-1374

Published: 01 September 2006

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Includes: Supplementary data

Journal Articles

Androgen-Dependent Regulation of Her-2/neu in Prostate Cancer Cells

Raanan Berger, Douglas I. Lin, Maria Nieto, Ewa Sicinska, Levi A. Garraway, Heiner Adams, Sabina Signoretti, William C. Hahn, Massimo Loda

Cancer Res (2006) 66 (11): 5723–5728.

DOI: https://doi.org/10.1158/0008-5472.CAN-05-3928

Published: 01 June 2006

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NARROW

Abstract 5648: Response and resistance to CDK2 and CDK4/6 inhibition in GIST

Abstract 960: RNF43 G659fs is an oncogenic mutation in colorectal cancer and sensitizes tumor cells to PI3K/mTOR inhibition

Abstract 260: Identifying cancer drug sensitivity using live cell imaging dynamic BH3 profiling of solid tumor core biopsies

Abstract 4478: High-throughput dynamic BH3 profiling identifies active cancer therapies in solid tumors

Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and Are Targetable by BET Bromodomain Inhibition

Abstract 5129: Fusobacterium and co-occurring microbes in primary and metastatic colorectal cancer

Abstract 5161: Inhibition of TBK1/IKBKE impacts tumor growth of KRAS-mutant colorectal cancers

Abstract 1759: Preclinical activity of selinexor, an inhibitor of XPO1/CRM1, in sarcoma

Abstract 607: Genomic analyses and novel models validate CDK4 as a therapeutic target in imatinib-resistant dermatofibrosarcoma protuberans

Abstract 3810: Selinexor (KPT-330), a novel selective inhibitor of nuclear export (SINE), shows single agent efficacy against alveolar soft part sarcoma (ASPS) in vivo

Abstract 168: Understanding the role of the carcinoid associated fibroblasts in the neuroendocrine tumor microenvironment

Abstract LB-270: Genomic amplification of c-Jun activates genes that promote proliferation and cell migration in liposarcoma

Abstract 4197: Mouse xenograft models of human soft tissue sarcomas

Abstract #LB-188: Unraveling the prostate cancer metabolome: Diagnostic and therapeutic implications

The Isopeptidase USP2a Protects Human Prostate Cancer from Apoptosis

Androgen-Dependent Regulation of Her-2/neu in Prostate Cancer Cells

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