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Journal Articles

Abstract A066 Acquired resistance to temozolomide in the Th-MYCN mouse as a clinically-relevant platform to evaluate novel therapeutic strategies against high-risk neuroblastoma

Evon Poon, Tong Liang, Giuseppe Barone, Barbara M. Costa, Sara Heuss, Simon P. Robinson, Charles Lin, Paul Workman, Yann Jamin, Louis Chesler
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement): A066.
https://doi.org/10.1158/1538-7445.PEDIATRIC24-A066
Published: 05 September 2024
View article titled, Abstract A066 Acquired resistance to temozolomide in the Th-<em>MYCN</em> mouse as a clinically-relevant platform to evaluate novel therapeutic strategies against high-risk neuroblastoma
Journal Articles

Abstract 4871: Dysregulation of MYC-family proteins sensitizes cancers to NMT inhibition: identification of NMTi sensitivity and mechanism

James Zhang, Gregor A. Lueg, Monica Faronato, Evon Poon, Andrii Gorelik, Andrea G. Grocin, Eva Caamano-Gutierrez, Francesco Falciani, Roberto Solari, Robin Carr, Andrew S. Bell, Edward Bartlett, Jennie Hutton, Miriam Llorian-Sopena, Probir Chakravarty, Bernadette Brzezicha, Martin Janz, Matther J. Garnett, Louis Chesler, Dinis P. Calado, Edward W. Tate
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4871.
https://doi.org/10.1158/1538-7445.AM2023-4871
Published: 04 April 2023
View article titled, Abstract 4871: Dysregulation of MYC-family proteins sensitizes cancers to NMT inhibition: identification of NMTi sensitivity and mechanism
Journal Articles

Noninvasive MRI Native T1 Mapping Detects Response to MYCN-targeted Therapies in the Th-MYCN Model of Neuroblastoma

Konstantinos Zormpas-Petridis, Evon Poon, Matthew Clarke, Neil P. Jerome, Jessica K.R. Boult, Matthew D. Blackledge, Fernando Carceller, Alexander Koers, Giuseppe Barone, Andrew D.J. Pearson, Lucas Moreno, John Anderson, Neil Sebire, Kieran McHugh, Dow-Mu Koh, Louis Chesler, Yinyin Yuan, Simon P. Robinson, Yann Jamin
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (16): 3424–3435.
https://doi.org/10.1158/0008-5472.CAN-20-0133
Published: 14 August 2020
View article titled, Noninvasive MRI Native T<sub>1</sub> Mapping Detects Response to <em>MYCN</em>-targeted Therapies in the Th-<em>MYCN</em> Model of Neuroblastoma
Open the PDF for Noninvasive MRI Native T<sub>1</sub> Mapping Detects Response to <em>MYCN</em>-targeted Therapies in the Th-<em>MYCN</em> Model of Neuroblastoma in another window
Includes: Supplementary data
Journal Articles

In Vivo Modeling of Chemoresistant Neuroblastoma Provides New Insights into Chemorefractory Disease and Metastasis

Orli Yogev, Gilberto S. Almeida, Karen T. Barker, Sally L. George, Colin Kwok, James Campbell, Magdalena Zarowiecki, Dimitrios Kleftogiannis, Laura M. Smith, Albert Hallsworth, Philip Berry, Till Möcklinghoff, Hannah T. Webber, Laura S. Danielson, Bliss Buttery, Elizabeth A. Calton, Barbara M. da Costa, Evon Poon, Yann Jamin, Stefano Lise, Gareth J. Veal, Neil Sebire, Simon P. Robinson, John Anderson, Louis Chesler
Journal: Cancer Research
Cancer Res (2019) 79 (20): 5382–5393.
https://doi.org/10.1158/0008-5472.CAN-18-2759
Published: 15 October 2019
View article titled, <em>In Vivo</em> Modeling of Chemoresistant Neuroblastoma Provides New Insights into Chemorefractory Disease and Metastasis
Open the PDF for <em>In Vivo</em> Modeling of Chemoresistant Neuroblastoma Provides New Insights into Chemorefractory Disease and Metastasis in another window
Includes: Supplementary data
Journal Articles

MRI Imaging of the Hemodynamic Vasculature of Neuroblastoma Predicts Response to Antiangiogenic Treatment

Konstantinos Zormpas-Petridis, Neil P. Jerome, Matthew D. Blackledge, Fernando Carceller, Evon Poon, Matthew Clarke, Ciara M. McErlean, Giuseppe Barone, Alexander Koers, Sucheta J. Vaidya, Lynley V. Marshall, Andrew D.J. Pearson, Lucas Moreno, John Anderson, Neil Sebire, Kieran McHugh, Dow-Mu Koh, Yinyin Yuan, Louis Chesler, Simon P. Robinson, Yann Jamin
Journal: Cancer Research
Series: Author Choice
Cancer Res (2019) 79 (11): 2978–2991.
https://doi.org/10.1158/0008-5472.CAN-18-3412
Published: 03 June 2019
View article titled, MRI Imaging of the Hemodynamic Vasculature of Neuroblastoma Predicts Response to Antiangiogenic Treatment
Open the PDF for MRI Imaging of the Hemodynamic Vasculature of Neuroblastoma Predicts Response to Antiangiogenic Treatment in another window
Includes: Supplementary data
Journal Articles

Abstract LB-201: MYC and TP53 defects interact at medulloblastoma relapse to define rapidly progressive disease and can be targeted therapeutically

Rebecca M. Hill, Sanne Kuijper, Janet Lindsey, Ed C. Schwalbe, Karen Barker, Jessica Boult, Daniel Williamson, Zai Ahmad, Albert Hallsworth, Sarra Ryan, Evon Poon, Simon Robinson, Ruth Ruddle, Florence Raynaud, Louise Howell, Colin Kwok, Abhijit Joshi, Sarah Nicholson, Stephen Crosier, Stephen Wharton, Tom Jacques, Keith Robson, Antony Michalski, Darren Hargrave, Barry Pizer, Simon Bailey, Fredrik J. Swartling, Kevin Petrie, William A. Weiss, Louis Chesler, Steve Clifford
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-201.
https://doi.org/10.1158/1538-7445.AM2014-LB-201
Published: 01 October 2014
View article titled, Abstract LB-201: MYC and TP53 defects interact at medulloblastoma relapse to define rapidly progressive disease and can be targeted therapeutically