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Journal Articles

Abstract 2471: Interpretable HPV detection in head and neck cancer using foundation models and synthetic digital pathology

Cancer Res (2025) 85 (8_Supplement_1): 2471.

https://doi.org/10.1158/1538-7445.AM2025-2471

Published: 21 April 2025

View articletitled, Abstract 2471: Interpretable HPV detection in head and neck cancer using foundation models and synthetic digital pathology

Journal Articles

Abstract 260: PDCD10 regulates Wnt activation-induced intestinal adenoma formation by promoting Wnt dependent stem cell function

Trisha Mondal, Sneha Kesaraju, Li Dong, Alex Ellerstein, Tong-Chuan He, Evgeny Izumchenko, Christopher R. Weber, Le Shen

Cancer Res (2025) 85 (8_Supplement_1): 260.

https://doi.org/10.1158/1538-7445.AM2025-260

Published: 21 April 2025

View articletitled, Abstract 260: PDCD10 regulates Wnt activation-induced intestinal adenoma formation by promoting Wnt dependent stem cell function

Journal Articles

Abstract LB047: Pdcd10 is a promising therapeutic target for head and neck squamous cell carcinoma

Manu Sundaresan, Xiangying Cheng, Claudia WIng, Alexander von Kumberg, Elena Jochum, Alka Singh, Joseph Kainov, Piao Zhao, Mohammed Sidahmed, Alexander T. Pearson, Ari J. Rosenberg, Nishant Agrawal, Le Shen, Evgeny Izumchenko

Cancer Res (2024) 84 (7_Supplement): LB047.

https://doi.org/10.1158/1538-7445.AM2024-LB047

Published: 05 April 2024

View articletitled, Abstract LB047: Pdcd10 is a promising therapeutic target for head and neck squamous cell carcinoma

Journal Articles

Abstract LB440: PRV131 is an effective and safe polymeric nanoparticle suspension for intratumoral cisplatin delivery

Manijeh Goldberg, Aaron Manzi, Stefanie Cantin, Peter Conway, Jonathan Shikora, Adelaide McFarland, Matt Cayer, Lillyanna Dunn, Courtney Ball, Alexander T. Pearson, Ari J. Rosenberg, Nishant Agrawal, Evgeny Izumchenko

Cancer Res (2024) 84 (7_Supplement): LB440.

https://doi.org/10.1158/1538-7445.AM2024-LB440

Published: 05 April 2024

View articletitled, Abstract LB440: PRV131 is an effective and safe polymeric nanoparticle suspension for intratumoral cisplatin delivery

Journal Articles

Abstract LB024: Permeation enhancer is necessary for the optimized PRV131 mediated cisplatin intratumoral delivery

Cancer Res (2024) 84 (7_Supplement): LB024.

https://doi.org/10.1158/1538-7445.AM2024-LB024

Published: 05 April 2024

View articletitled, Abstract LB024: Permeation enhancer is necessary for the optimized PRV131 mediated cisplatin intratumoral delivery

Journal Articles

Abstract 3933: Comprehensive molecular characterization of mitochondrial mutational landscape across the evolution of lung adenocarcinoma

Alka Singh, Santanu Dasgupta, Ashwin L. Koppayi, Lisa Rooper, Vasudha Mishra, David Sidransky, Nishant Agrawal, Karthik Suresh, Evgeny Izumchenko

Cancer Res (2024) 84 (6_Supplement): 3933.

https://doi.org/10.1158/1538-7445.AM2024-3933

Published: 22 March 2024

View articletitled, Abstract 3933: Comprehensive molecular characterization of mitochondrial mutational landscape across the evolution of lung adenocarcinoma

Journal Articles

Abstract 4756: NSD1/2 histone methyltransferases regulate cell growth in HPV-negative head and neck squamous cell carcinoma (HNSCC)

Iuliia Topchu, Igor Bychkov, Petr Makhov, Evgeny Izumchenko, John Karanicolas, Jindan Yu, Jochen Lorch, Yanis Boumber

Cancer Res (2023) 83 (7_Supplement): 4756.

https://doi.org/10.1158/1538-7445.AM2023-4756

Published: 04 April 2023

View articletitled, Abstract 4756: NSD1/2 histone methyltransferases regulate cell growth in HPV-negative head and neck squamous cell carcinoma (HNSCC)

Journal Articles

Abstract 4845: Ultra-deep sequencing of mitochondrial genome to explore the dynamic mutational changes associated with oral cavity squamous cell carcinoma progression

Alka Singh, Ashwin Lakshman Koppayi, Ping Wu, Mark Lingen, Vasudha Mishra, Alexander Pearson, Ari Rosenberg, Nishant Agrawal, Karthik Suresh, Evgeny Izumchenko

Cancer Res (2023) 83 (7_Supplement): 4845.

https://doi.org/10.1158/1538-7445.AM2023-4845

Published: 04 April 2023

View articletitled, Abstract 4845: Ultra-deep sequencing of mitochondrial genome to explore the dynamic mutational changes associated with oral cavity squamous cell carcinoma progression

Journal Articles

Abstract 4407: Clinicopathologic characteristics and mutational analysis of MYC amplified head and neck squamous cell carcinoma (HNSCC)

Thomas Cyberski, Alka Singh, Mark Lingen, Alexander Pearson, Nishant Agrawal, Evgeny Izumchenko, Ari Rosenberg

Cancer Res (2023) 83 (7_Supplement): 4407.

https://doi.org/10.1158/1538-7445.AM2023-4407

Published: 04 April 2023

View articletitled, Abstract 4407: Clinicopathologic characteristics and mutational analysis of MYC amplified head and neck squamous cell carcinoma (HNSCC)

Journal Articles

Abstract 4897: PRT543, a methyl transferase inhibitor, has potent anti-tumor activity against adenoid cystic carcinoma of salivary glands

Vasudha Mishra, Alka Singh, Xiangying Chen, Michael Korzinkin, Claudia Wing, Viktoria Sarkisova, Alexandra Ozerova, Oksana Glushchenko, Venkat Thodima, Koichi Ito, Peggy Scherle, Mark Lingen, Rifat Hasina, Alexander Pearson, Ari Rosenberg, Alex Zhavoronkov, Bruce Ruggeri, Nishant Agrawal, Evgeny Izumchenko

Cancer Res (2023) 83 (7_Supplement): 4897.

https://doi.org/10.1158/1538-7445.AM2023-4897

Published: 04 April 2023

View articletitled, Abstract 4897: PRT543, a methyl transferase inhibitor, has potent anti-tumor activity against adenoid cystic carcinoma of salivary glands

Journal Articles

Abstract 6077: Comprehensive multi-omic characterization of genetic changes associated with sinonasal squamous cell carcinoma progression

Alka Singh, Nikita Babushkin, Michael Korzinkin, Viktoria Sarkisova, Vasudha Mishra, Ari Rosenberg, Mark Lingen, Justin Bishop, Alex Zhavoronkov, Nyall London, Nishant Agrawal, Xuanyao Liu, Evgeny Izumchenko

Cancer Res (2023) 83 (7_Supplement): 6077.

https://doi.org/10.1158/1538-7445.AM2023-6077

Published: 04 April 2023

View articletitled, Abstract 6077: Comprehensive multi-omic characterization of genetic changes associated with sinonasal squamous cell carcinoma progression

Journal Articles

Abstract 6192: MSI2 regulates DNA damage response signaling and tumor progression in murine NSCLC

Igor Bychkov, Alexander Deneka, Iuliia Topchu, Rajendra P. Pangeni, Christopher Lengner, Evgeny Izumchenko, Jyoti Patel, John Karanicolas, Petr Makhov, Yanis Boumber

Cancer Res (2023) 83 (7_Supplement): 6192.

https://doi.org/10.1158/1538-7445.AM2023-6192

Published: 04 April 2023

View articletitled, Abstract 6192: MSI2 regulates DNA damage response signaling and tumor progression in murine NSCLC

Journal Articles

Abstract 813: Doublecortin-like kinase 1 (DCLK1) and NOTCH1 pathways lead to poor prognosis in HNSCC

Esther Channah Broner, Lisa Rooper, Tejaswini Subbannayya, Aditi Chatterjee, David Sidransky, Evgeny Izumchenko

Cancer Res (2020) 80 (16_Supplement): 813.

https://doi.org/10.1158/1538-7445.AM2020-813

Published: 15 August 2020

View articletitled, Abstract 813: Doublecortin-like kinase 1 (DCLK1) and NOTCH1 pathways lead to poor prognosis in HNSCC

Journal Articles

Abstract P5-05-13: Inhibition of NOTCH signaing with g-secretase inhibitor AL101 contributes to overcome resistance against HER2-targeted therapy in HER2 amplified breast cancer cells

Bothaina Nakad, Esther Channah Broner, David Sidransky, Evgeny Izumchenko

Cancer Res (2020) 80 (4_Supplement): P5-05-13.

https://doi.org/10.1158/1538-7445.SABCS19-P5-05-13

Published: 15 February 2020

View articletitled, Abstract P5-05-13: Inhibition of NOTCH signaing with g-secretase inhibitor AL101 contributes to overcome resistance against HER2-targeted therapy in HER2 amplified breast cancer cells

Journal Articles

Abstract 3060: YAP1 induces STAT3 phosphorylation & combined blockade enhances chemotherapeutic efficacy

Masahiro Shibata, Akira Ooki, Yoshikuni Inokawa, Evgeny Izumchenko, Enrico Munari, Giuseppe Bogina, Edward Gabrielson, Anju Singh, Mohammad Obaidul Hoque

Cancer Res (2019) 79 (13_Supplement): 3060.

https://doi.org/10.1158/1538-7445.AM2019-3060

Published: 01 July 2019

View articletitled, Abstract 3060: YAP1 induces STAT3 phosphorylation & combined blockade enhances chemotherapeutic efficacy

Journal Articles

Abstract 4885: AL101 mediated tumor inhibition in Notch mutated ACC PDX models

Renata ferrarotto*, Genia Alpert*, Udi Gluschnaider, Rami Rauch, Adi Mondshine, Oz Solomon, Bill Kramer, Evgeny Izumchenko, John Heymach, Andrea Vergara-Silva, Jon Aster, Matti Davis

Cancer Res (2019) 79 (13_Supplement): 4885.

https://doi.org/10.1158/1538-7445.AM2019-4885

Published: 01 July 2019

View articletitled, Abstract 4885: AL101 mediated tumor inhibition in Notch mutated ACC PDX models

Journal Articles

Abstract 3443: Doublecortin-like kinase 1 (DCLK1) is novel Notch pathway signaling regulator in HNSCC

Esther Channah Broner, Tejaswini Subbannayya, Alex Zhavoronkov, Mike Korzinkin, Artem Artemov, Ivan Ozerov, Ido Sloma, David Sidransky, Aditi Chatterjee, Evgeny Izumchenko

Cancer Res (2019) 79 (13_Supplement): 3443.

https://doi.org/10.1158/1538-7445.AM2019-3443

Published: 01 July 2019

View articletitled, Abstract 3443: Doublecortin-like kinase 1 (DCLK1) is novel Notch pathway signaling regulator in HNSCC

Journal Articles

Abstract 3420: Discovery of genetic alterations governing sinonasal squamous cell carcinoma tumorigenesis

Adrian D. Schubert, Nyall R. London, Justin A. Bishop, Esther C. Broner, David Sidransky, Evgeny Izumchenko

Cancer Res (2018) 78 (13_Supplement): 3420.

https://doi.org/10.1158/1538-7445.AM2018-3420

Published: 01 July 2018

View articletitled, Abstract 3420: Discovery of genetic alterations governing sinonasal squamous cell carcinoma tumorigenesis

Journal Articles

Abstract 2750: An epigenetic and immunologic approach to optimize therapy for HNSCC

Rachel Goldberg, Masahiro Shibata, Evgeny Izumchenko, Luigi Marchionni, David Sidransky, Mohammad O. Hoque

Cancer Res (2018) 78 (13_Supplement): 2750.

https://doi.org/10.1158/1538-7445.AM2018-2750

Published: 01 July 2018

View articletitled, Abstract 2750: An epigenetic and immunologic approach to optimize therapy for HNSCC

Journal Articles

Integrated Analysis of Whole-Genome ChIP-Seq and RNA-Seq Data of Primary Head and Neck Tumor Samples Associates HPV Integration Sites with Open Chromatin Marks

Cancer Res (2017) 77 (23): 6538–6550.

https://doi.org/10.1158/0008-5472.CAN-17-0833

Published: 30 November 2017

View articletitled, Integrated Analysis of Whole-Genome ChIP-Seq and RNA-Seq Data of Primary Head and Neck Tumor Samples Associates HPV Integration Sites with Open Chromatin Marks

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Abstract 2471: Interpretable HPV detection in head and neck cancer using foundation models and synthetic digital pathology

Abstract 260: PDCD10 regulates Wnt activation-induced intestinal adenoma formation by promoting Wnt dependent stem cell function

Abstract LB047: Pdcd10 is a promising therapeutic target for head and neck squamous cell carcinoma

Abstract LB440: PRV131 is an effective and safe polymeric nanoparticle suspension for intratumoral cisplatin delivery

Abstract LB024: Permeation enhancer is necessary for the optimized PRV131 mediated cisplatin intratumoral delivery

Abstract 3933: Comprehensive molecular characterization of mitochondrial mutational landscape across the evolution of lung adenocarcinoma

Abstract 4756: NSD1/2 histone methyltransferases regulate cell growth in HPV-negative head and neck squamous cell carcinoma (HNSCC)

Abstract 4845: Ultra-deep sequencing of mitochondrial genome to explore the dynamic mutational changes associated with oral cavity squamous cell carcinoma progression

Abstract 4407: Clinicopathologic characteristics and mutational analysis of MYC amplified head and neck squamous cell carcinoma (HNSCC)

Abstract 4897: PRT543, a methyl transferase inhibitor, has potent anti-tumor activity against adenoid cystic carcinoma of salivary glands

Abstract 6077: Comprehensive multi-omic characterization of genetic changes associated with sinonasal squamous cell carcinoma progression

Abstract 6192: MSI2 regulates DNA damage response signaling and tumor progression in murine NSCLC

Abstract 813: Doublecortin-like kinase 1 (DCLK1) and NOTCH1 pathways lead to poor prognosis in HNSCC

Abstract P5-05-13: Inhibition of NOTCH signaing with g-secretase inhibitor AL101 contributes to overcome resistance against HER2-targeted therapy in HER2 amplified breast cancer cells

Abstract 3060: YAP1 induces STAT3 phosphorylation & combined blockade enhances chemotherapeutic efficacy

Abstract 4885: AL101 mediated tumor inhibition in Notch mutated ACC PDX models

Abstract 3443: Doublecortin-like kinase 1 (DCLK1) is novel Notch pathway signaling regulator in HNSCC

Abstract 3420: Discovery of genetic alterations governing sinonasal squamous cell carcinoma tumorigenesis

Abstract 2750: An epigenetic and immunologic approach to optimize therapy for HNSCC

Integrated Analysis of Whole-Genome ChIP-Seq and RNA-Seq Data of Primary Head and Neck Tumor Samples Associates HPV Integration Sites with Open Chromatin Marks

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