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Abstract B055: Harnessing cytomegalovirus immunity against pancreatic tumors for immunotherapy

Remi Marrocco, Jay Patel, Rithika Medari, Siming Sun, Kevin Gulay, Alexei Martsinkovskiy, Simon Brunel, Eduardo Lucero-Meza, Evangeline Mose, Andrew Lowy, Chris Benedict, Tatiana Hurtado de Mendoza

Cancer Res (2024) 84 (17_Supplement_2): B055.

https://doi.org/10.1158/1538-7445.PANCREATIC24-B055

Published: 15 September 2024

View articletitled, Abstract B055: Harnessing cytomegalovirus immunity against pancreatic tumors for immunotherapy

Journal Articles

Abstract A052: Silencing MICAL2 Expression in Pancreatic Cancer Cells rewires the tumor microenvironment through the IL1-a/p38 MAP kinase/STAT-3 axis and Sensitizes Tumors to Immune Checkpoint Blockade therapy

Bharti Garg, Evangeline Mose, Edgar Esparaza, Jay Patel, Rithika Medari, Alexei Martsinkovskiy, Carrie Bishop, Gissele Gonzalez, Adam Engler, Parag Katira, Herve Tiriac, Andrew M Lowy

Cancer Res (2024) 84 (17_Supplement_2): A052.

https://doi.org/10.1158/1538-7445.PANCREATIC24-A052

Published: 15 September 2024

View articletitled, Abstract A052: Silencing MICAL2 Expression in Pancreatic Cancer Cells rewires the tumor microenvironment through the IL1-a/p38 MAP kinase/STAT-3 axis and Sensitizes Tumors to Immune Checkpoint Blockade therapy

Journal Articles

Abstract 2979: Pancreatic cancer cells upregulate LPAR4 in response to isolation stress to create a fibronectin-rich extracellular matrix niche and promote tumor initiation

Chengsheng Wu, Taha Rakhshandehroo, Hiromi I. Wettersten, Alejandro Campos, Tami Von Schalscha, Shashi Jain, Ziqi Yu, Jiali Tan, Evangeline Mose, Betzaira G. Childers, Andrew M. Lowy, Sara M. Weis, David A. Cheresh

Cancer Res (2024) 84 (6_Supplement): 2979.

https://doi.org/10.1158/1538-7445.AM2024-2979

Published: 22 March 2024

View articletitled, Abstract 2979: Pancreatic cancer cells upregulate LPAR4 in response to isolation stress to create a fibronectin-rich extracellular matrix niche and promote tumor initiation

Journal Articles

Abstract 2470: Harnessing cytomegalovirus immunity against pancreatic tumors for immunotherapy

Remi Marrocco, Jay Patel, Siming Sun, Rithika Medari, Kevin Gulay, Eduardo Lucero-Meza, Evangeline Mose, Andrew Lowy, Chris Benedict, Tatiana Hurtado de Mendoza

Cancer Res (2024) 84 (6_Supplement): 2470.

https://doi.org/10.1158/1538-7445.AM2024-2470

Published: 22 March 2024

View articletitled, Abstract 2470: Harnessing cytomegalovirus immunity against pancreatic tumors for immunotherapy

Journal Articles

Abstract A039: Silencing MICAL2 expression in pancreatic cancer cells reduces IL-1A expression and inhibits tumor growth through a CD8+ T cell dependent mechanism

Bharti Garg, EvanGeline Mose, Edgar Esparza, Jay Patel, Sarah Sass, Alexei Martsinkovskiy, Dawn Jacquish, Herve Tiriac, Andrew M. Lowy

Cancer Res (2024) 84 (2_Supplement): A039.

https://doi.org/10.1158/1538-7445.PANCA2023-A039

Published: 16 January 2024

View articletitled, Abstract A039: Silencing MICAL2 expression in pancreatic cancer cells reduces IL-1A expression and inhibits tumor growth through a CD8+ T cell dependent mechanism

Journal Articles

Abstract B017: MICAL2 promotes pancreatic cancer growth and metastasis independent of MRTF-A signaling

Sohini Khan, Shweta Sharma, Divya Sood, Bharti Garg, Dawn Jaquish, Evangeline Mose, Edgar Esparza, Herve Tiriac, Andrew M. Lowy

Cancer Res (2022) 82 (22_Supplement): B017.

https://doi.org/10.1158/1538-7445.PANCA22-B017

Published: 15 November 2022

View articletitled, Abstract B017: MICAL2 promotes pancreatic cancer growth and metastasis independent of MRTF-A signaling

Journal Articles

Abstract C044: MICAL2 expression in pancreatic cancer cells modulates the tumor microenvironment through the TGF beta pathway

Bharti Garg, Shweta Sharma, Sohini Khan, Edgar Esparza, Sarah Sass, Dawn Jacquish, Evangeline Mose, Herve Tiriac, Andrew Lowy

Cancer Res (2022) 82 (22_Supplement): C044.

https://doi.org/10.1158/1538-7445.PANCA22-C044

Published: 15 November 2022

View articletitled, Abstract C044: MICAL2 expression in pancreatic cancer cells modulates the tumor microenvironment through the TGF beta pathway

Journal Articles

Abstract A72: Protein isoforms of the RON tyrosine kinase receptor transform human pancreatic ductal epithelial cells and induce acinar to ductal metaplasia

Jeffery M. Chakedis, Randall French, Michele Babicky, Dawn Jaquish, Haleigh Howard, Evangeline Mose, Jaclyn Miyamoto, Zakk Walterscheid, Patrick Holman, Andrew M. Lowy

Cancer Res (2015) 75 (13_Supplement): A72.

https://doi.org/10.1158/1538-7445.PANCA2014-A72

Published: 30 June 2015

View articletitled, Abstract A72: Protein isoforms of the RON tyrosine kinase receptor transform human pancreatic ductal epithelial cells and induce acinar to ductal metaplasia

Journal Articles

Abstract 2315: Demethylating therapy modulates expression of the RON tyrosine kinase receptor in pancreatic cancer

Jeffery Chakedis, Randall French, Dawn Jaquish, Evangeline Mose, Andrew Lowy

Cancer Res (2014) 74 (19_Supplement): 2315.

https://doi.org/10.1158/1538-7445.AM2014-2315

Published: 01 October 2014

View articletitled, Abstract 2315: Demethylating therapy modulates expression of the RON tyrosine kinase receptor in pancreatic cancer

Journal Articles

Abstract 5191: Genome-wide mutational analysis reveals core signaling pathways in mucinous neoplasms of the appendix

Hakan Alakus, Michele Babicky, Pradipta Ghosh, Shawn Yost, Kristen Jepsen, Yang Dai, Angelo Arias, Michael Samuels, Evangeline Mose, Michael Peterson, Andrew Lowy, Kelly Frazer, Olivier Harismendy

Cancer Res (2014) 74 (19_Supplement): 5191.

https://doi.org/10.1158/1538-7445.AM2014-5191

Published: 01 October 2014

View articletitled, Abstract 5191: Genome-wide mutational analysis reveals core signaling pathways in mucinous neoplasms of the appendix

Journal Articles

Abstract 4208: Suppressor of Cytokine Signaling (SOCS)-3 and the C-X-C chemokines CXCL1 and CXCL2 promote tumor aggessiveness and radiation resistance in pancreatic cancer

Sisi Jiang, Evangeline Mose, Giovanni Coppola, Andrew Lowy, Christina Jamieson, Nicholas A. Cacalano

Cancer Res (2014) 74 (19_Supplement): 4208.

https://doi.org/10.1158/1538-7445.AM2014-4208

Published: 01 October 2014

View articletitled, Abstract 4208: Suppressor of Cytokine Signaling (SOCS)-3 and the C-X-C chemokines CXCL1 and CXCL2 promote tumor aggessiveness and radiation resistance in pancreatic cancer

Journal Articles

Abstract B54: RON overexpression drives macrophage differentiation toward an alternatively activated (M2) phenotype in a mouse model of spontaneous pancreatic carcinogenesis.

Michele L. Babicky, Megan M. Harper, Evangeline Mose, Dawn Jaquish, Randall French, Andrew M. Lowy

Cancer Res (2012) 72 (14_Supplement): B54.

https://doi.org/10.1158/1538-7445.PANCA2012-B54

Published: 03 April 2014

View articletitled, Abstract B54: RON overexpression drives macrophage differentiation toward an alternatively activated (M2) phenotype in a mouse model of spontaneous pancreatic carcinogenesis.

Journal Articles

Abstract 3019: Alternative transcription of the RON tyrosine kinase receptor in human pancreatic adenocarcinoma generates active protein isoforms.

Jeffery Chakedis, Randall French, Michele Babicky, Megan Harper, Dawn Jaquish, Evangeline Mose, Andrew Lowy

Cancer Res (2013) 73 (8_Supplement): 3019.

https://doi.org/10.1158/1538-7445.AM2013-3019

Published: 15 April 2013

View articletitled, Abstract 3019: Alternative transcription of the RON tyrosine kinase receptor in human pancreatic adenocarcinoma generates active protein isoforms.

Journal Articles

KRas Induces a Src/PEAK1/ErbB2 Kinase Amplification Loop That Drives Metastatic Growth and Therapy Resistance in Pancreatic Cancer

Jonathan A. Kelber, Theresa Reno, Sharmeela Kaushal, Cristina Metildi, Tracy Wright, Konstantin Stoletov, Jessica M. Weems, Frederick D. Park, Evangeline Mose, Yingchun Wang, Robert M. Hoffman, Andrew M. Lowy, Michael Bouvet, Richard L. Klemke

Cancer Res (2012) 72 (10): 2554–2564.

https://doi.org/10.1158/0008-5472.CAN-11-3552

Published: 14 May 2012

View articletitled, KRas Induces a Src/PEAK1/ErbB2 Kinase Amplification Loop That Drives Metastatic Growth and Therapy Resistance in Pancreatic Cancer

Includes: Supplementary data

Journal Articles

Abstract 4167: KRas induces a Src/PEAK1/ErbB2 kinase amplification loop to drive pancreatic cancer growth, metastasis and therapy resistance

Jonathan A. Kelber, Theresa Reno, Sharmeela Kaushal, Cristina Metildi, Konstantin Stoletov, Jessica Weems, Fred D. Park, Tracy Wright, Evangeline Mose, Robert M. Hoffman, Andrew M. Lowy, Michael M. Bouvet, Richard L. Klemke

Cancer Res (2012) 72 (8_Supplement): 4167.

https://doi.org/10.1158/1538-7445.AM2012-4167

Published: 15 April 2012

View articletitled, Abstract 4167: KRas induces a Src/PEAK1/ErbB2 kinase amplification loop to drive pancreatic cancer growth, metastasis and therapy resistance

Journal Articles

Silencing of RON Receptor Signaling Promotes Apoptosis and Gemcitabine Sensitivity in Pancreatic Cancers

Jocelyn Logan-Collins, Ryan M. Thomas, Peter Yu, Dawn Jaquish, Evangeline Mose, Randall French, William Stuart, Rebecca McClaine, Bruce Aronow, Robert M. Hoffman, Susan E. Waltz, Andrew M. Lowy

Cancer Res (2010) 70 (3): 1130–1140.

https://doi.org/10.1158/0008-5472.CAN-09-0761

Published: 31 January 2010

View articletitled, Silencing of RON Receptor Signaling Promotes Apoptosis and Gemcitabine Sensitivity in Pancreatic Cancers

Journal Articles

High level of α1-antichymotrypsin is associated with the metastatic phenotype in a human breast cancer model

Valerie N. Montel, Kersi N. Pestonjamasp, Evangeline Mose, David Tarin

Cancer Res (2004) 64 (7_Supplement): 415.

Published: 01 April 2004

View articletitled, High level of α1-antichymotrypsin is associated with the metastatic phenotype in a human breast cancer model

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Abstract B055: Harnessing cytomegalovirus immunity against pancreatic tumors for immunotherapy

Abstract A052: Silencing MICAL2 Expression in Pancreatic Cancer Cells rewires the tumor microenvironment through the IL1-a/p38 MAP kinase/STAT-3 axis and Sensitizes Tumors to Immune Checkpoint Blockade therapy

Abstract 2979: Pancreatic cancer cells upregulate LPAR4 in response to isolation stress to create a fibronectin-rich extracellular matrix niche and promote tumor initiation

Abstract 2470: Harnessing cytomegalovirus immunity against pancreatic tumors for immunotherapy

Abstract A039: Silencing MICAL2 expression in pancreatic cancer cells reduces IL-1A expression and inhibits tumor growth through a CD8+ T cell dependent mechanism

Abstract B017: MICAL2 promotes pancreatic cancer growth and metastasis independent of MRTF-A signaling

Abstract C044: MICAL2 expression in pancreatic cancer cells modulates the tumor microenvironment through the TGF beta pathway

Abstract A72: Protein isoforms of the RON tyrosine kinase receptor transform human pancreatic ductal epithelial cells and induce acinar to ductal metaplasia

Abstract 2315: Demethylating therapy modulates expression of the RON tyrosine kinase receptor in pancreatic cancer

Abstract 5191: Genome-wide mutational analysis reveals core signaling pathways in mucinous neoplasms of the appendix

Abstract 4208: Suppressor of Cytokine Signaling (SOCS)-3 and the C-X-C chemokines CXCL1 and CXCL2 promote tumor aggessiveness and radiation resistance in pancreatic cancer

Abstract B54: RON overexpression drives macrophage differentiation toward an alternatively activated (M2) phenotype in a mouse model of spontaneous pancreatic carcinogenesis.

Abstract 3019: Alternative transcription of the RON tyrosine kinase receptor in human pancreatic adenocarcinoma generates active protein isoforms.

KRas Induces a Src/PEAK1/ErbB2 Kinase Amplification Loop That Drives Metastatic Growth and Therapy Resistance in Pancreatic Cancer

Abstract 4167: KRas induces a Src/PEAK1/ErbB2 kinase amplification loop to drive pancreatic cancer growth, metastasis and therapy resistance

Silencing of RON Receptor Signaling Promotes Apoptosis and Gemcitabine Sensitivity in Pancreatic Cancers

High level of α1-antichymotrypsin is associated with the metastatic phenotype in a human breast cancer model

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