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Eva Corey
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Journal Articles

Supraphysiological Androgens Promote the Tumor Suppressive Activity of the Androgen Receptor through cMYC Repression and Recruitment of the DREAM Complex

Michael D. Nyquist, Ilsa M. Coleman, Jared M. Lucas, Dapei Li, Brian Hanratty, Hannah Meade, Elahe A. Mostaghel, Stephen R. Plymate, Eva Corey, Michael C. Haffner, Peter S. Nelson
Journal: Cancer Research
Cancer Res (2023) 83 (17): 2938–2951.
https://doi.org/10.1158/0008-5472.CAN-22-2613
Published: 01 September 2023
View article titled, Supraphysiological Androgens Promote the Tumor Suppressive Activity of the Androgen Receptor through cMYC Repression and Recruitment of the DREAM Complex
Open the PDF for Supraphysiological Androgens Promote the Tumor Suppressive Activity of the Androgen Receptor through cMYC Repression and Recruitment of the DREAM Complex in another window
Includes: Supplementary data
Journal Articles

Abstract A005: Androgen receptor variants mRNA absolute quantification in prostate cancer cell models

Gabrianne Larson, Zoi Sychev, Stephen Plymate, Eva Corey, Justin M. Drake
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): A005.
https://doi.org/10.1158/1538-7445.PRCA2023-A005
Published: 02 June 2023
View article titled, Abstract A005: Androgen receptor variants mRNA absolute quantification in prostate cancer cell models
Journal Articles

Abstract B004: Genomic loss of TP53 impairs AR-targeted activity in metastatic prostate cancer

Wanting Han, Michael D. Nyquist, Ilsa Coleman, Navonil De Sarkar, Lisa Ang, Eva Corey, Peter S. Nelson
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): B004.
https://doi.org/10.1158/1538-7445.PRCA2023-B004
Published: 02 June 2023
View article titled, Abstract B004: Genomic loss of TP53 impairs AR-targeted activity in metastatic prostate cancer
Journal Articles

Abstract B020: BCL2 expression is enriched in AR-independent advanced prostate cancer

Daniel Westaby, Juan M. Jimenez-Vacas, Ines Figueiredo, Claire Pettinger, Bora Gurel, Denisa Bogdan, Jan Rekowski, Lorenzo Buroni, Antje Neeb, Ruth Riisnaes, Mateus Crespo, Susana Miranda, Ana Ferreira, Daniel Nava Rodrigues, George Seed, Claudia Bertan, Maria de los Dolores Fenor de la Maza, Christina Guo, Juliet Carmichael, Rafael Grochot, Khobe Chandran, Andreas Varkaris, Steven P. Balk, Wei Yuan, Suzanne Carreira, Peter S. Nelson, Michael Haffner, Eva Corey, Johann de Bono, Adam Sharp
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): B020.
https://doi.org/10.1158/1538-7445.PRCA2023-B020
Published: 02 June 2023
View article titled, Abstract B020: BCL2 expression is enriched in AR-independent advanced prostate cancer
Journal Articles

Abstract B065: Combining the androgen receptor inhibitor darolutamide with PI3K/AKT/mTOR pathway inhibitors has superior efficacy in preclinical models of prostate cancer

Simon Heller, Tatsuo Sugawara, Ekaterina Nevedomskaya, Simon J. Baumgart, Holly Nguyen, Eva Corey, Annika Böhme, Oliver von Ahsen, Oliver Politz, Bernard Haendler
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): B065.
https://doi.org/10.1158/1538-7445.PRCA2023-B065
Published: 02 June 2023
View article titled, Abstract B065: Combining the androgen receptor inhibitor darolutamide with PI3K/AKT/mTOR pathway inhibitors has superior efficacy in preclinical models of prostate cancer
Journal Articles

Abstract PR005: Multi-level functional genomics reveals molecular and cellular oncogenicity of patient-based 3’ untranslated region mutations

Samantha L. Schuster, Sonali Arora, Cynthia L. Wladyka, Lukas Corey, Bethany L. Stackhouse, Lori Kollath, Eva Corey, Lawrence D. True, Dave Young, Patrick J. Paddison, Andrew C. Hsieh
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): PR005.
https://doi.org/10.1158/1538-7445.PRCA2023-PR005
Published: 02 June 2023
View article titled, Abstract PR005: Multi-level functional genomics reveals molecular and cellular oncogenicity of patient-based 3’ untranslated region mutations
Journal Articles

Abstract B070: Global proteomics and phosphoproteomics profiling of prostate cancer patient derived xenografts tumors from the LuCaP series

Zoi E. Sychev, Gabbrianne E. Larson, Hannah E. Bergom, Abderrahman E. Day, Megan E. Ludwig, Atef E. Ali, Eva Corey, Stephen R. Plymate, Justin E. Hwang, Justin M. Drake
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): B070.
https://doi.org/10.1158/1538-7445.PRCA2023-B070
Published: 02 June 2023
View article titled, Abstract B070: Global proteomics and phosphoproteomics profiling of prostate cancer patient derived xenografts tumors from the LuCaP series
Journal Articles

LSD1 Inhibition Disrupts Super-Enhancer–Driven Oncogenic Transcriptional Programs in Castration-Resistant Prostate Cancer

Muqing Li, Mingyu Liu, Wanting Han, Zifeng Wang, Dong Han, Susan Patalano, Jill A. Macoska, Steven P. Balk, Housheng Hansen He, Eva Corey, Shuai Gao, Changmeng Cai
Journal: Cancer Research
Cancer Res (2023) 83 (10): 1684–1698.
https://doi.org/10.1158/0008-5472.CAN-22-2433
Published: 15 May 2023
View article titled, LSD1 Inhibition Disrupts Super-Enhancer–Driven Oncogenic Transcriptional Programs in Castration-Resistant Prostate Cancer
Open the PDF for LSD1 Inhibition Disrupts Super-Enhancer–Driven Oncogenic Transcriptional Programs in Castration-Resistant Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract LB298: Molecular phenotype classification of metastatic prostate cancer by cell-free DNA methylation analysis

Mohamed Adil, Brian Hanratty, Pallabi Mustafi, Ilsa Coleman, Radhika Patel, Anna-Lisa Doebley, Robert Patton, Eden Cruikshank, Patricia Galipeau, Ruth Dumpit, Martine Roudier, Jin-Yih Low, Navonil De Sarkar, Robert Montgomery, Eva Corey, Colm Morrissey, Peter Nelson, Gavin Ha, Michael Haffner
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): LB298.
https://doi.org/10.1158/1538-7445.AM2023-LB298
Published: 14 April 2023
View article titled, Abstract LB298: Molecular phenotype classification of metastatic prostate cancer by cell-free DNA methylation analysis
Journal Articles

Abstract 2411: Di-ganglioside GD2 expression and role in promoting tumorigenicity in prostate cancer

Aaqib M. Bhat, Bhopal C. Mohapatra, Insha Mushtaq, Sukanya Chakraborty, Samikshan Dutta, Sameer Mirza, Matthew D. Storck, Subodh M. Lele, Ming-Fong Lin, Bruce J. Trock, Karen S. Sfanos, Colm Morrissey, Eva Corey, Jonathan Melamed, Leah Cook, Kaustubh Datta, Jane Meza, Jawed Siddiqui, Surinder K. Batra, Vimla Band, Hamid Band
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2411.
https://doi.org/10.1158/1538-7445.AM2022-2411
Published: 15 June 2022
View article titled, Abstract 2411: Di-ganglioside GD2 expression and role in promoting tumorigenicity in prostate cancer
Journal Articles

Abstract 651: Combination of the androgen receptor inhibitor darolutamide and the PI3K inhibitor copanlisib leads to improved anti-tumor efficacy and apoptosis in prostate cancer models

Tatsuo Sugawara, Holly NGuyen, Eva Corey, Ekaterina Nevedomskaya, Oliver Politz, Dominik Mumberg, Bernard Haendler
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 651.
https://doi.org/10.1158/1538-7445.AM2022-651
Published: 15 June 2022
View article titled, Abstract 651: Combination of the androgen receptor inhibitor darolutamide and the PI3K inhibitor copanlisib leads to improved anti-tumor efficacy and apoptosis in prostate cancer models
Journal Articles

Abstract 273: Prostate cancer metastasis induces irregular bone formation associated to specific androgen dependent phenotypes

Felipe Eltit, Qiong Wang, Raphaële Charest-Morin, Colm Morrissey, Eva Corey, Rizhi Wang, Michael E. Cox
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 273.
https://doi.org/10.1158/1538-7445.AM2022-273
Published: 15 June 2022
View article titled, Abstract 273: Prostate cancer metastasis induces irregular bone formation associated to specific androgen dependent phenotypes
Journal Articles

RNA Splicing Factors SRRM3 and SRRM4 Distinguish Molecular Phenotypes of Castration-Resistant Neuroendocrine Prostate Cancer

Mark P. Labrecque, Lisha G. Brown, Ilsa M. Coleman, Bryce Lakely, Nicholas J. Brady, John K. Lee, Holly M. Nguyen, Dapei Li, Brian Hanratty, Michael C. Haffner, David S. Rickman, Lawrence D. True, Daniel W. Lin, Hung-Ming Lam, Joshi J. Alumkal, Eva Corey, Peter S. Nelson, Colm Morrissey
Journal: Cancer Research
Cancer Res (2021) 81 (18): 4736–4750.
https://doi.org/10.1158/0008-5472.CAN-21-0307
Published: 15 September 2021
View article titled, RNA Splicing Factors SRRM3 and SRRM4 Distinguish Molecular Phenotypes of Castration-Resistant Neuroendocrine Prostate Cancer
Open the PDF for RNA Splicing Factors SRRM3 and SRRM4 Distinguish Molecular Phenotypes of Castration-Resistant Neuroendocrine Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 1458: Targeting fibroblast growth factor receptors in castration-resistant prostate cancer

Mark P. Labrecque, Lisha G. Brown, Ilsa M. Coleman, Bryce Lakely, Holly M. Nguyen, Eva Corey, Peter S. Nelson, Colm Morrissey
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1458.
https://doi.org/10.1158/1538-7445.AM2021-1458
Published: 01 July 2021
View article titled, Abstract 1458: Targeting fibroblast growth factor receptors in castration-resistant prostate cancer
Journal Articles

Abstract 1141: CDK9 inhibition is selective for transcriptionally addicted tumors harboring MYC genomic amplifications

Melinda A. Day, Nikolaus D. Obholzer, Akanksha Pandey, Tom Chen, Tong Liang, Rosa A. Villagomez, Mulini Pingili, Jost V. Koren, David B. Freeman, Holly M. Nguyen, Jennifer L. Conor, Eva Corey, Matthew G. Reese, Andrew Boghossian, Brienne Engel, Melissa M. Ronan, Jennifer A. Roth, Joesph P. Vacca, Peter B. Rahl, Marius S. Pop, Benjamin W. Trotter, Charles Y. Lin, Jorge C. DiMartino, Pavan Kumar, Douglas C. Saffran
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1141.
https://doi.org/10.1158/1538-7445.AM2021-1141
Published: 01 July 2021
View article titled, Abstract 1141: CDK9 inhibition is selective for transcriptionally addicted tumors harboring <em>MYC</em> genomic amplifications
Journal Articles

Ferroptosis Inducers Are a Novel Therapeutic Approach for Advanced Prostate Cancer

Ali Ghoochani, En-Chi Hsu, Merve Aslan, Meghan A. Rice, Holly M. Nguyen, James D. Brooks, Eva Corey, Ramasamy Paulmurugan, Tanya Stoyanova
Journal: Cancer Research
Cancer Res (2021) 81 (6): 1583–1594.
https://doi.org/10.1158/0008-5472.CAN-20-3477
Published: 15 March 2021
View article titled, Ferroptosis Inducers Are a Novel Therapeutic Approach for Advanced Prostate Cancer
Open the PDF for Ferroptosis Inducers Are a Novel Therapeutic Approach for Advanced Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 3083: Selective inhibition of transcription factor BRN2 as a treatment strategy for Small Cell Prostate Cancer

Daksh Thaper, Ravi Munuganti, Adeleke Aguda, Soojin Kim, Shungyu Ku, Sahil Kumar, Sepideh Vahid, Shaghayegh Nouruzi, Olena Sivak, Dwaiyapan Ganguli, Colm Morrissey, Eva Corey, Himisha Beltran, Amina Zoubeidi
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3083.
https://doi.org/10.1158/1538-7445.AM2020-3083
Published: 15 August 2020
View article titled, Abstract 3083: Selective inhibition of transcription factor BRN2 as a treatment strategy for Small Cell Prostate Cancer
Journal Articles

Abstract 4127: Niraparib is active against prostate xenograft models that are wild type or defective for DNA damage repair genes

Linda A. Snyder, Krista Menard, Georges Habineza Ndikuyeze, Holly M. Nguyen, Anna Hughes, Lorraine Angelillo, Gerald Chu, Jenny Driscoll, Rebecca Hawkins, Eva Corey
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4127.
https://doi.org/10.1158/1538-7445.AM2020-4127
Published: 15 August 2020
View article titled, Abstract 4127: Niraparib is active against prostate xenograft models that are wild type or defective for DNA damage repair genes
Journal Articles

Abstract LB-030: Interferon signaling contributes to prostate cancer drug resistance

Supreet Agarwal, Kerry McGowen, Fathi Elloumi, Maggie Cam, Mike Beshiri, Eva Corey, Kathleen Kelly
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-030.
https://doi.org/10.1158/1538-7445.AM2019-LB-030
Published: 01 July 2019
View article titled, Abstract LB-030: Interferon signaling contributes to prostate cancer drug resistance
Journal Articles

Abstract 2962: Targeting BCL2 as a therapeutic strategy in neuroendocrine prostate cancer

Alexandra N. Corella, Jared M. Lucas, Arja Kaipainen, Ilsa M. Coleman, Colm Morrissey, Eva Corey, Paul Nghiem, David MacPherson, Peter S. Nelson
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2962.
https://doi.org/10.1158/1538-7445.AM2019-2962
Published: 01 July 2019
View article titled, Abstract 2962: Targeting BCL2 as a therapeutic strategy in neuroendocrine prostate cancer