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Journal Articles

Abstract 266: Adaptation of colorectal cancer cells to the brain microenvironment: The role of IRS2

Inbal Greenberg, Anat Klein, Rachel Grossman, Ethan Sokol, Eilam Yeini, Paula Ofek, Ronit Satchi-Fainaro, Bertrand Liang, Hadas Reuveni, Tami Rubinek, Ido Wolf

Cancer Res (2022) 82 (12_Supplement): 266.

DOI: https://doi.org/10.1158/1538-7445.AM2022-266

Published: 15 June 2022

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Journal Articles

Abstract 1249: Development of a pan-cancer algorithm to predict homologous recombination deficiency and sensitivity to PARPi therapy

Emmanuel Antonarakis, Jay Moore, Dexter Jin, Tim Chen, Justin Newberg, Zoe Fleischmann, Karthikeyan Murugesan, Garrett Frampton, David Fabrizio, Russell Madison, Ethan Sokol

Cancer Res (2022) 82 (12_Supplement): 1249.

DOI: https://doi.org/10.1158/1538-7445.AM2022-1249

Published: 15 June 2022

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Journal Articles

Abstract PD4-09: Comprehensive assessment of the genomic landscape of breast cancer brain metastases reveals targetable alterations and genomic signatures relevant to immune-checkpoint and PARP inhibitors

Athina Giannoudis, Ethan Sokol, Shakti H Ramkissoon, Talvinder Bhogal, Kimberly McGregor, Allison Clark, Evangelia D Razis, Rupert Bartsch, Richard SP Huang, Carlo Palmieri

Cancer Res (2022) 82 (4_Supplement): PD4-09.

DOI: https://doi.org/10.1158/1538-7445.SABCS21-PD4-09

Published: 15 February 2022

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Journal Articles

Abstract P5-07-04: Comprehensive analysis of the gene rearrangements within 822 breast cancer brain metastases reveals an enrichment of cyclin dependent kinase 12 rearrangements in HER2-positive brain metastases

Talvinder Bhogal, Ethan Sokol, Shakti Ramkissoon, Athina Giannoudis, Kimberly McGregor, Allison Clark, Evangelia Razis, Rupert Bartsch, Richard Huang, Carlo Palmieri

Cancer Res (2022) 82 (4_Supplement): P5-07-04.

DOI: https://doi.org/10.1158/1538-7445.SABCS21-P5-07-04

Published: 15 February 2022

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Journal Articles

Abstract P5-13-02: Serially biopsied BRCA1/2 mutant breast tumors frequently acquire alterations in BRCA1, BRCA2, and CREBBP

Ethan Sokol, Smruthy Sivakumar, Brennan Decker, Jeffrey Ross, Priti Hegde

Cancer Res (2022) 82 (4_Supplement): P5-13-02.

DOI: https://doi.org/10.1158/1538-7445.SABCS21-P5-13-02

Published: 15 February 2022

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Journal Articles

Abstract P3-09-10: NTRK1/2/3 fusions are observed in both secretory and non-secretory breast cancers

Ethan Sokol, Sophia Maund, Jeffrey Ross, Timothy Wilson

Cancer Res (2022) 82 (4_Supplement): P3-09-10.

DOI: https://doi.org/10.1158/1538-7445.SABCS21-P3-09-10

Published: 15 February 2022

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Journal Articles

Abstract PD14-09: APOBEC signature, clinical characteristics, and outcome in hormone receptor-positive (HR+) HER2-negative (HER2-) breast cancer (BC) patients (pts) in real-world data (RWD)

Saranya Chumsri, Kira Raskina, Sarah Sammons, Laura Alder, Natalie Danziger, Alexa B Schrock, Kim McGregor, Ethan Sokol

Cancer Res (2022) 82 (4_Supplement): PD14-09.

DOI: https://doi.org/10.1158/1538-7445.SABCS21-PD14-09

Published: 15 February 2022

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Journal Articles

Abstract 2854: Adaptation of colorectal cancer cells to the brain microenvironment: the role of IRS2

Inbal Greenberg, Anat Klein, Rachel Grossman, Ethan Sokol, Eilam Yeini, Paula Ofek, Ronit Satchi-Fainaro, Bertrand Liang, Hadas Reuveni, Tami Rubinek, Ido Wolf

Cancer Res (2021) 81 (13_Supplement): 2854.

DOI: https://doi.org/10.1158/1538-7445.AM2021-2854

Published: 01 July 2021

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Journal Articles

Abstract PD8-01: Comprehensive genomic profiling (CGP) of metastatic invasive lobular carcinomas reveals heterogeneity in immune biomarkers and resistance alterations across biopsy sites

Ethan Sokol, Dexter X Jin, Jeffrey Ross, Garrett M Frampton, Steffi Oesterreich

Cancer Res (2021) 81 (4_Supplement): PD8-01.

DOI: https://doi.org/10.1158/1538-7445.SABCS20-PD8-01

Published: 15 February 2021

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Journal Articles

Abstract PO-003: Adaptation of colorectal cancer cells to the brain microenvironment: The role of IRS2

Inbal Greenberg, Anat Klein, Rachel Grossman, Ethan Sokol, Eilam Yeini, Paula Ofek, Ronit Satchi-Fainaro, Hadas Reuveni, Tami Rubinek, Ido Wolf

Cancer Res (2020) 80 (23_Supplement): PO-003.

DOI: https://doi.org/10.1158/1538-7445.EPIMETAB20-PO-003

Published: 02 December 2020

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Journal Articles

Abstract LB-063: ARID1A mutations induce an EGFR-like gene expression signature and confer intrinsic and acquired resistance to cetuximab treatment in first line metastatic CRC

Radia Marie Johnson, Xueping Qu, Joshua Thomas, Yvonne Kschonsak, Ling-Yuh Huw, Fang-Shu Ou, Ethan Sokol, Nnamdi Ihuegbu, Oliver Zill, Omar Kabbarah, Anneleen Daemen, Richard Bourgon, Alan Venook, Federico Innocenti, Heinz-Josef Lenz, Felipe de Sousa e Melo, Carlos Bais

Cancer Res (2020) 80 (16_Supplement): LB-063.

DOI: https://doi.org/10.1158/1538-7445.AM2020-LB-063

Published: 15 August 2020

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Journal Articles

Abstract 5671: Alignment of TMB measured on clinical samples: Phase IIB of the Friends of Cancer Research TMB Harmonization Project

Cancer Res (2020) 80 (16_Supplement): 5671.

DOI: https://doi.org/10.1158/1538-7445.AM2020-5671

Published: 15 August 2020

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Journal Articles

Abstract 5869: Characterization and therapeutic implications of SMARCA4 mutations in cancer

Tharu M. Fernando, Robert Piskol, Russell Bainer, Ethan Sokol, Sally Trabucco, Qing Zhang, Huong Trinh, Sophia Maund, Marc Kschonsak, Subhra Chaudhuri, Tom Januario, Zora Modrusan, Robert L. Yauch

Cancer Res (2020) 80 (16_Supplement): 5869.

DOI: https://doi.org/10.1158/1538-7445.AM2020-5869

Published: 15 August 2020

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Journal Articles

Abstract 4894: Incidence of high tumor mutation burden (TMB) and PD-L1 positivity in breast cancers and potential response to immune checkpoint inhibitors (ICPIs)

Ethan Sokol, Lee Albacker, Aixa Soyano, Ricardo Parrondo, Brenda Ernst, Emmanuel Gabriel, Garrett Frampton, Jeffrey Ross, Siraj Ali, Jon Chung, Saranya Chumsri

Cancer Res (2019) 79 (13_Supplement): 4894.

DOI: https://doi.org/10.1158/1538-7445.AM2019-4894

Published: 01 July 2019

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Journal Articles

Abstract 2363: Novel CDH1 mutations in breast invasive lobular carcinoma

Garrett M. Frampton, Ryan Hartmaier, Ethan Sokol, Anika Gupta, Joel Greenbowe, Steven Roels, Laurie Gay, Philip J. Stephens

Cancer Res (2018) 78 (13_Supplement): 2363.

DOI: https://doi.org/10.1158/1538-7445.AM2018-2363

Published: 01 July 2018

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NARROW

Abstract 266: Adaptation of colorectal cancer cells to the brain microenvironment: The role of IRS2

Abstract 1249: Development of a pan-cancer algorithm to predict homologous recombination deficiency and sensitivity to PARPi therapy

Abstract PD4-09: Comprehensive assessment of the genomic landscape of breast cancer brain metastases reveals targetable alterations and genomic signatures relevant to immune-checkpoint and PARP inhibitors

Abstract P5-07-04: Comprehensive analysis of the gene rearrangements within 822 breast cancer brain metastases reveals an enrichment of cyclin dependent kinase 12 rearrangements in HER2-positive brain metastases

Abstract P5-13-02: Serially biopsied BRCA1/2 mutant breast tumors frequently acquire alterations in BRCA1, BRCA2, and CREBBP

Abstract P3-09-10: NTRK1/2/3 fusions are observed in both secretory and non-secretory breast cancers

Abstract PD14-09: APOBEC signature, clinical characteristics, and outcome in hormone receptor-positive (HR+) HER2-negative (HER2-) breast cancer (BC) patients (pts) in real-world data (RWD)

Abstract 2854: Adaptation of colorectal cancer cells to the brain microenvironment: the role of IRS2

Abstract PD8-01: Comprehensive genomic profiling (CGP) of metastatic invasive lobular carcinomas reveals heterogeneity in immune biomarkers and resistance alterations across biopsy sites

Abstract PO-003: Adaptation of colorectal cancer cells to the brain microenvironment: The role of IRS2

Abstract LB-063: ARID1A mutations induce an EGFR-like gene expression signature and confer intrinsic and acquired resistance to cetuximab treatment in first line metastatic CRC

Abstract 5671: Alignment of TMB measured on clinical samples: Phase IIB of the Friends of Cancer Research TMB Harmonization Project

Abstract 5869: Characterization and therapeutic implications of SMARCA4 mutations in cancer

Abstract 4894: Incidence of high tumor mutation burden (TMB) and PD-L1 positivity in breast cancers and potential response to immune checkpoint inhibitors (ICPIs)

Abstract 2363: Novel CDH1 mutations in breast invasive lobular carcinoma

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