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Journal Articles

Delineating The RAS Conformational Landscape

Mitchell I. Parker, Joshua E. Meyer, Erica A. Golemis, Roland L. Dunbrack

Cancer Res canres.0804.2022.

DOI: https://doi.org/10.1158/0008-5472.CAN-22-0804

Published: 10 May 2022

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Includes: Supplementary data

Journal Articles

Nedd9 Restrains Autophagy to Limit Growth of Early Stage Non–Small Cell Lung Cancer

Alexander Y. Deneka, Meghan C. Kopp, Anna S. Nikonova, Anna V. Gaponova, Anna A. Kiseleva, Harvey H. Hensley, Douglas B. Flieder, Ilya G. Serebriiskii, Erica A. Golemis

Cancer Res (2021) 81 (13): 3717–3726.

DOI: https://doi.org/10.1158/0008-5472.CAN-20-3626

Published: 01 July 2021

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Includes: Supplementary data

Journal Articles

Abstract 349: Association of DNA damage response capacity with neoadjuvant chemoradiation response in locally advanced rectal cancer

Elena V. Demidova, Randy W. Lesh, Vladimir Avkshtol, Margret B. Einarson, Erica A. Golemis, Sanjeevani Arora, Joshua E. Meyer

Cancer Res (2021) 81 (13_Supplement): 349.

DOI: https://doi.org/10.1158/1538-7445.AM2021-349

Published: 01 July 2021

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Journal Articles

Abstract 808: Functional evaluation of novel germline DNA repair variants identified in patients with early-onset renal cancer

Elena V. Demidova, Waleed Iqbal, Ilya G. Serebriiskii, Andrea F. Forman, Tatiana Kent, Richard T. Pomerantz, Erica A. Golemis, Michael J. Hall, David Y. Chen, Mary B. Daly, Sanjeevani Arora

Cancer Res (2021) 81 (13_Supplement): 808.

DOI: https://doi.org/10.1158/1538-7445.AM2021-808

Published: 01 July 2021

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Journal Articles

Abstract C06: Cholesterol deprivation induces TGFβ signaling to promote basal differentiation in pancreatic cancer

Linara Gabitova, Suraj Peri, Ralph Francescone, Janusz Franco-Barraza, Neelima Shah, Emmanuelle Nicolas, Elizabeth A. Handorf, Kathy Q. Cai, Ido Sloma, Rachel Chiaverelli, Richard Moffitt, Erica A. Golemis, Carolyn Fang, Shannon Lynch, Edna Cukierman, Igor Astsaturov

Cancer Res (2019) 79 (24_Supplement): C06.

DOI: https://doi.org/10.1158/1538-7445.PANCA19-C06

Published: 13 December 2019

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Journal Articles

Abstract 955: Musashi-2 regulates EGFR expression in NSCLC, cell proliferation and survival, response to EGFR inhibitors in EGFR-mutant NSCLC

Alexander Kudinov, Petr Makhov, Bulat Faezov, Igor Bychkov, Alexander Deneka, Emmanuelle Nicolas, Kathy Q Q. Caid, Rohan Brebione, Eleanor Avrilf, Anna S. Nikonova, Ilya G. Serebriiskii, Hossein Borghaei, Erica A. Golemis, Yanis Boumber

Cancer Res (2019) 79 (13_Supplement): 955.

DOI: https://doi.org/10.1158/1538-7445.AM2019-955

Published: 01 July 2019

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Journal Articles

Abstract 3459: PKD1 regulates susceptibility to ulcerative colitis and colorectal cancer

Anna S. Nikonova, Anna Kiseleva, Ilya Serebriiskii, Sergei Grivennikov, Erica A. Golemis

Cancer Res (2019) 79 (13_Supplement): 3459.

DOI: https://doi.org/10.1158/1538-7445.AM2019-3459

Published: 01 July 2019

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Journal Articles

Abstract 4452: Musashi-2 regulates EGFR/HER3 expression in NSCLC, cell proliferation and response to EGFR inhibitors in EGFR-mutant NSCLC

Peter Makhov, Alexander Kudinov, Alexander Deneka, Brian L. Egleston, Emmanuelle Nicolas, Kathy Q. Cai, Rohan Brebion, Eleanor Avril, Mark Hitrik, Anna S. Nikonova, Ilya G. Serebriiskii, Vladimir Khazak, Hossein Borghaei, Erica A. Golemis, Yanis Boumber

Cancer Res (2018) 78 (13_Supplement): 4452.

DOI: https://doi.org/10.1158/1538-7445.AM2018-4452

Published: 01 July 2018

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Journal Articles

Abstract 5814: Synthetic lethal therapy to overcome resistance to AURKA inhibition in HPV-negative head and neck cancer

Alexander Y. Deneka, Margret B. Einarson, Jong Woo Lee, Anna S. Nikonova, Barbara Burtness, Erica A. Golemis

Cancer Res (2018) 78 (13_Supplement): 5814.

DOI: https://doi.org/10.1158/1538-7445.AM2018-5814

Published: 01 July 2018

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Journal Articles

Abstract 3878: Musashi-2 (MSI2) regulation of ERBB family proteins in non-small cell lung cancer (NSCLC)

Alexander Kudinov, Alexander Deneka, Anna N. Nikonova, Emmanuelle Nicolas, Vladislav A. Korobeynikov, Ilya G. Serebriiskii, John Karanicolas, Erica A. Golemis, Yanis Boumber

Cancer Res (2017) 77 (13_Supplement): 3878.

DOI: https://doi.org/10.1158/1538-7445.AM2017-3878

Published: 01 July 2017

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Journal Articles

Abstract 5286: A pipeline for developing a novel, predictive tool to classify variants of uncertain significance (VUS) in Lynch Syndrome

Sanjeevani Arora, Peter J. Huwe, Rahmat Sikder, Manali Shah, Sanat Deshpande, Michael J. Hall, Roland L. Dunbrack, Erica A. Golemis

Cancer Res (2016) 76 (14_Supplement): 5286.

DOI: https://doi.org/10.1158/1538-7445.AM2016-5286

Published: 15 July 2016

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Journal Articles

Abstract 1584: Musashi-2 (MSI2) drives TGFBR1/SMAD3 dependent partial EMT and supports VEGFR2 expression and metastasis of human and mouse NSCLC cells

Alexander Kudinov, Alexander Deneka, Anna Nikonova, Ilya Serebriiskii, Tim N. Beck, Qi Cai, Brian L. Egleston, Emmanuelle Nicolas, Hossein Borghaei, Don Gibbons, Jonathan Kurie, Erica A. Golemis, Yanis Boumber

Cancer Res (2016) 76 (14_Supplement): 1584.

DOI: https://doi.org/10.1158/1538-7445.AM2016-1584

Published: 15 July 2016

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Journal Articles

Abstract B25: Anti-Mullerian hormone (AMH) supports epithelial identity and survival signaling in lung cancer

Tim N. Beck, Vladislav Korobeynikov, Alexander Kudinov, Rachel Georgeopoulos, Emmanuelle Nicolas, Margret B. Einarson, Yan Zhou, Yanis Boumber, David A. Proia, Ilya G. Serebriiskii, Erica A. Golemis

Cancer Res (2016) 76 (3_Supplement): B25.

DOI: https://doi.org/10.1158/1538-7445.FBCR15-B25

Published: 07 April 2016

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Journal Articles

Abstract 537: Information-driven approaches to predicting familial risk for prostate cancer

Emmanuelle Nicolas, Yan Zhou, Ilya G. Serebriiskii, Mark D. Andrake, Elizabeth A. Handorf, Roland L. Dunbrack, Veda N. Giri, Eric A. Ross, Erica A. Golemis, Michael J. Hall, Mary B. Daly

Cancer Res (2015) 75 (15_Supplement): 537.

DOI: https://doi.org/10.1158/1538-7445.AM2015-537

Published: 01 August 2015

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Journal Articles

Abstract 1716: Acquisition of estrogen independence induces TOB1-related mechanisms supporting breast cancer cell proliferation

Yong-Wei Zhang, Rochelle E. Nasto, Rency Varghese, Sandra A. Jablonski, Ilya G. Serebriiskii, Rishi Surana, Valerie S. Calvert, Ionut Bebu, Joseph Murray, Lu Jin, Michael Johnson, Rebecca Riggins, Habtom Ressom, Emmanuel Petricoin III, Robert Clarke, Erica A. Golemis, Louis M. Weiner

Cancer Res (2015) 75 (15_Supplement): 1716.

DOI: https://doi.org/10.1158/1538-7445.AM2015-1716

Published: 01 August 2015

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Journal Articles

Abstract 989: NEDD9 expression promotes epithelial ovarian cancer growth and dissemination

Rashid Gabbasov, Laura E. Bickel, Shane W. O'Brien, Samuel Litwin, Sachiko Seo, Erica A. Golemis, Denise C. Connolly

Cancer Res (2014) 74 (19_Supplement): 989.

DOI: https://doi.org/10.1158/1538-7445.AM2014-989

Published: 01 October 2014

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Journal Articles

Abstract 276: Targeting signaling networks via RNAi to improve therapy for ovarian cancer

Hanqing Liu, Ilya Serebriiskii, Margret B. Einarson, Anna Pecherskaya, Yan Zhou, Harsh Pathak, Andrew K. Godwin, Erica A. Golemis

Cancer Res (2012) 72 (8_Supplement): 276.

DOI: https://doi.org/10.1158/1538-7445.AM2012-276

Published: 15 April 2012

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Journal Articles

Enhanced Genetic Instability and Dasatinib Sensitivity in Mammary Tumor Cells Lacking NEDD9

Mahendra K. Singh, Eugene Izumchenko, Andres J. Klein-Szanto, Brian L. Egleston, Marina Wolfson, Erica A. Golemis

Cancer Res (2010) 70 (21): 8907–8916.

DOI: https://doi.org/10.1158/0008-5472.CAN-10-0353

Published: 31 October 2010

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Journal Articles

Abstract 3257: NEDD9 is required for initiation of HER2/Neu-dependent mammary tumor development

Joy L. Little, Eugene Izumchenko, Mahendra K. Singh, Sachiko Seo, Mineo Kurokawa, Brian L. Egleston, Andres Klein-Szanto, Erica A. Golemis

Cancer Res (2010) 70 (8_Supplement): 3257.

DOI: https://doi.org/10.1158/1538-7445.AM10-3257

Published: 15 April 2010

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Journal Articles

Abstract 5098: Targeting the cholesterol pathway gene SC4MOL sensitizes cancer to EGFR inhibitors

Anna L. Sukhanova, Tetyana Bagnyukova, Lisa E. Kratz, Richard I. Kelley, Ilya G. Serebriiskii, Louis M. Weiner, Erica A. Golemis, Igor A. Astsaturov

Cancer Res (2010) 70 (8_Supplement): 5098.

DOI: https://doi.org/10.1158/1538-7445.AM10-5098

Published: 15 April 2010

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NARROW

Delineating The RAS Conformational Landscape

Nedd9 Restrains Autophagy to Limit Growth of Early Stage Non–Small Cell Lung Cancer

Abstract 349: Association of DNA damage response capacity with neoadjuvant chemoradiation response in locally advanced rectal cancer

Abstract 808: Functional evaluation of novel germline DNA repair variants identified in patients with early-onset renal cancer

Abstract C06: Cholesterol deprivation induces TGFβ signaling to promote basal differentiation in pancreatic cancer

Abstract 955: Musashi-2 regulates EGFR expression in NSCLC, cell proliferation and survival, response to EGFR inhibitors in EGFR-mutant NSCLC

Abstract 3459: PKD1 regulates susceptibility to ulcerative colitis and colorectal cancer

Abstract 4452: Musashi-2 regulates EGFR/HER3 expression in NSCLC, cell proliferation and response to EGFR inhibitors in EGFR-mutant NSCLC

Abstract 5814: Synthetic lethal therapy to overcome resistance to AURKA inhibition in HPV-negative head and neck cancer

Abstract 3878: Musashi-2 (MSI2) regulation of ERBB family proteins in non-small cell lung cancer (NSCLC)

Abstract 5286: A pipeline for developing a novel, predictive tool to classify variants of uncertain significance (VUS) in Lynch Syndrome

Abstract 1584: Musashi-2 (MSI2) drives TGFBR1/SMAD3 dependent partial EMT and supports VEGFR2 expression and metastasis of human and mouse NSCLC cells

Abstract B25: Anti-Mullerian hormone (AMH) supports epithelial identity and survival signaling in lung cancer

Abstract 537: Information-driven approaches to predicting familial risk for prostate cancer

Abstract 1716: Acquisition of estrogen independence induces TOB1-related mechanisms supporting breast cancer cell proliferation

Abstract 989: NEDD9 expression promotes epithelial ovarian cancer growth and dissemination

Abstract 276: Targeting signaling networks via RNAi to improve therapy for ovarian cancer

Enhanced Genetic Instability and Dasatinib Sensitivity in Mammary Tumor Cells Lacking NEDD9

Abstract 3257: NEDD9 is required for initiation of HER2/Neu-dependent mammary tumor development

Abstract 5098: Targeting the cholesterol pathway gene SC4MOL sensitizes cancer to EGFR inhibitors

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