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Journal Articles

Abstract 899: Remarkable anti-tumor response in a HCC transgenic mouse model treated with GNS561 in combination with anti-PD1

Madani Rachid, Annemilaï Tijeras-Raballand, Cindy Serdjebi, Sonia Brun, Christelle Ansaldi, Eric Raymond, Philippe Halfon
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 899.
https://doi.org/10.1158/1538-7445.AM2020-899
Published: 15 August 2020
View article titled, Abstract 899: Remarkable anti-tumor response in a HCC transgenic mouse model treated with GNS561 in combination with anti-PD1
Journal Articles

Abstract 5103: Bidirectional EMT-dependent modulation of cancer cell and M1/M2 macrophage differentiation

Lucile Astorgues-Xerri, Matthieu Martinet, Eric Raymond, Sandrine Faivre, Annemilaï Tijeras-Raballand
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5103.
https://doi.org/10.1158/1538-7445.AM2020-5103
Published: 15 August 2020
View article titled, Abstract 5103: Bidirectional EMT-dependent modulation of cancer cell and M1/M2 macrophage differentiation
Journal Articles

Abstract 5312: Imeglimin alone or in combination with sorafenib showed potent anti-tumor effect in human hepatocellular carcinoma: A new kid on the block for HCC treatment

Annemilaï Tijeras-Raballand, Matthieu Martinet, Valérie Paradis, Jean-Pierre Bizzari, Eric Janin, Eric Raymond
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5312.
https://doi.org/10.1158/1538-7445.AM2020-5312
Published: 15 August 2020
View article titled, Abstract 5312: Imeglimin alone or in combination with sorafenib showed potent anti-tumor effect in human hepatocellular carcinoma: A new kid on the block for HCC treatment
Journal Articles

Abstract 1636: Diet-variants and immune characterization of a stage-defined, transgenic immunocompetent mouse model of HCC (ASV-B)

Annemilaï Tijeras-Raballand, Christian Hobeika, Philippe Bonnin, Benoit Rousseau, Aurélie Rodrigues, Fouad Ladfil, Marc Pocard, Armand de Gramont, Eric Raymond, Sandrine Faivre, Valérie Paradis, Clarisse Eveno
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1636.
https://doi.org/10.1158/1538-7445.AM2020-1636
Published: 15 August 2020
View article titled, Abstract 1636: Diet-variants and immune characterization of a stage-defined, transgenic immunocompetent mouse model of HCC (ASV-B)
Journal Articles

Abstract 3684: Basal Notch1 and Notch4 activation as potential markers of aggressiveness and sensitivity to Notch inhibition in human cancer cell lines

Lucile Astorgues-Xerri, Matthieu Martinet, Eric Raymond, Annemilaï Tijeras-Raballand
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3684.
https://doi.org/10.1158/1538-7445.AM2020-3684
Published: 15 August 2020
View article titled, Abstract 3684: Basal Notch1 and Notch4 activation as potential markers of aggressiveness and sensitivity to Notch inhibition in human cancer cell lines
Journal Articles

Abstract 1080: Link between M1/M2 human macrophages and epithelial-mesenchymal status in head and neck cancer cell lines

Lucile Astorgues-Xerri, Diane Evrard, Matthieu Martinet, Eric Raymond, Sandrine Faivre, Annemilaï Tijeras-Raballand
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1080.
https://doi.org/10.1158/1538-7445.AM2019-1080
Published: 01 July 2019
View article titled, Abstract 1080: Link between M1/M2 human macrophages and epithelial-mesenchymal status in head and neck cancer cell lines
Journal Articles

Abstract 91: Diet-variants and immune characterization of a stage-defined, transgenic immunocompetent mouse model of HCC (ASV-B)

Annemilaï Tijeras-Raballand, Christian Hobeika, Benoit Rousseau, Patricia Hainaud, Philippe Bonnin, Aurélie Rodrigues, Fouad Ladfil, Marc Pocard, Valérie Paradis, Armand de Gramont, Eric Raymond, Evelyne Dupuy, Clarisse Eveno, Sandrine Faivre
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 91.
https://doi.org/10.1158/1538-7445.AM2019-91
Published: 01 July 2019
View article titled, Abstract 91: Diet-variants and immune characterization of a stage-defined, transgenic immunocompetent mouse model of HCC (ASV-B)
Journal Articles

Abstract 859: Basal Notch4 activation is a druggable marker of aggressiveness in a panel of human cancer cell lines

Lucile Astorgues-Xerri, Matthieu Martinet, Eric Raymond, Sandrine Faivre, Annemilaï Tijeras-Raballand
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 859.
https://doi.org/10.1158/1538-7445.AM2019-859
Published: 01 July 2019
View article titled, Abstract 859: Basal Notch4 activation is a druggable marker of aggressiveness in a panel of human cancer cell lines
Journal Articles

Abstract 2944: TGF-β inhibitor galunisertib combined with antiangiogenic therapies showed antitumor effects in vitro and in vivo in hepatocellular carcinoma (HCC)

Annemilaï Tijeras-Raballand, Christian Hobeika, Matthieu Martinet, Lucile Astorgues-Xerri, Elise Paven, Marie-Aude Le Bitoux, Anne Maillard, Clarisse Eveno, Marc Pocard, Philippe Bonnin, Alexandre Harari, Eric Raymond, Sandrine Faivre, Armand de Gramont
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2944.
https://doi.org/10.1158/1538-7445.AM2018-2944
Published: 01 July 2018
View article titled, Abstract 2944: TGF-β inhibitor galunisertib combined with antiangiogenic therapies showed antitumor effects in vitro and in vivo in hepatocellular carcinoma (HCC)
Journal Articles

Abstract 2501: Involvement of Notch signaling pathway in a panel of human cancer cell lines

Lucile Astorgues-Xerri, Mathieu Martinet, Jinan Abdullah, Sandrine Faivre, Eric Raymond, Annemilaï Tijeras-Raballand
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2501.
https://doi.org/10.1158/1538-7445.AM2018-2501
Published: 01 July 2018
View article titled, Abstract 2501: Involvement of Notch signaling pathway in a panel of human cancer cell lines
Journal Articles

Abstract 2043: PlGF/VEGFR-1-dependent activation of Dll4/Notch4 pathway contributes to liver vessel abnormalities and tumor growth in hepatocellular carcinoma

Annemilaï Tijeras-Raballand, Christian Hobeika, Jean-Olivier Contreres, Patricia Hainaud, Matthieu Martinet, Philippe Bonnin, Clarisse Eveno, Evelyne Dupuy, Marc Pocard, Valerie Paradis, Eric Raymond, Sandrine Faivre, Armand de Gramont
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2043.
https://doi.org/10.1158/1538-7445.AM2018-2043
Published: 01 July 2018
View article titled, Abstract 2043: PlGF/VEGFR-1-dependent activation of Dll4/Notch4 pathway contributes to liver vessel abnormalities and tumor growth in hepatocellular carcinoma
Journal Articles

Abstract 4096: Stage-defined, transgenic immunocompetent mouse model (ASV-B) to investigate new drugs for hepatocellular carcinoma

Annemilaï Tijeras-Raballand, Patricia Hainaud, Christian Hobeika, Clarisse Eveno, Marc Pocard, Philippe Bonnin, Valérie Paradis, Mohamed Bouattour, Eric Raymond, Armand de Gramont, Evelyne Dupuy, Sandrine Faivre
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4096.
https://doi.org/10.1158/1538-7445.AM2018-4096
Published: 01 July 2018
View article titled, Abstract 4096: Stage-defined, transgenic immunocompetent mouse model (ASV-B) to investigate new drugs for hepatocellular carcinoma
Journal Articles

Abstract 5124: GNS561 a new quinoline derivative inhibits the growth of hepatocellular carcinoma in a cirrhotic rat and human PDX orthotopic mouse models

Firas BASSISSI, Zuzana Macek Jilkova, Sonia Brun, Jerome Courcambeck, Jennifer Tracz, Keerthi Kurma, Gaël S. Roth, Cindy Khaldi, Corinne Chaimbault, Benoit Quentin, Emilie Asseraf, Antoine Beret, Eric Raymond, Philippe Halfon, Thomas Decaens
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5124.
https://doi.org/10.1158/1538-7445.AM2017-5124
Published: 01 July 2017
View article titled, Abstract 5124: GNS561 a new quinoline derivative inhibits the growth of hepatocellular carcinoma in a cirrhotic rat and human PDX orthotopic mouse models
Journal Articles

Abstract 1914: GNS561 is a new quinoline derivative with high efficacy on cancer stem cells from colorectal liver metastasis and hepatocellular carcinoma

Firas Bassissi, Elena Patricia Gifu, Sonia Brun, Jerome Courcambeck, Antoine Beret, Jean Marc Pascussi, Julie Pannequin, Eric Raymond, Philippe Halfon, Philippe Merle, Claude Caron de Fromentel
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1914.
https://doi.org/10.1158/1538-7445.AM2017-1914
Published: 01 July 2017
View article titled, Abstract 1914: GNS561 is a new quinoline derivative with high efficacy on cancer stem cells from colorectal liver metastasis and hepatocellular carcinoma
Journal Articles

Abstract 4044: LY3039579, a novel Notch inhibit, potentiates the anti-tumoral effects of sorafenib in hepatocellular carcinoma (HCC)

Annemilai Tijeras-Raballand, Christian Hobeika, Elise Payen, Matthieu Martinet, Philippe Bonnin, Karim A. Benhadji, Bharvin R. Patel, Clarisse Eveno, Marc Pocard, Sandrine Faivre, Eric Raymond, Armand de Gramont
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4044.
https://doi.org/10.1158/1538-7445.AM2017-4044
Published: 01 July 2017
View article titled, Abstract 4044: LY3039579, a novel Notch inhibit, potentiates the anti-tumoral effects of sorafenib in hepatocellular carcinoma (HCC)
Journal Articles

Abstract 29: Addition of Galunisertib to DC101 increased angiogenesis inhibition and tumor growth control in hepatocellular carcinoma (HCC)

Annemilai Tijeras-Raballand, Christian Hobeika, Elise Payen, Matthieu Martinet, Philippe Bonnin, Karim A. Benhadji, Clarisse Eveno, Marc Pocard, Sandrine Faivre, Eric Raymond, Armand de Gramont
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 29.
https://doi.org/10.1158/1538-7445.AM2017-29
Published: 01 July 2017
View article titled, Abstract 29: Addition of Galunisertib to DC101 increased angiogenesis inhibition and tumor growth control in hepatocellular carcinoma (HCC)
Journal Articles

Abstract B57: Effects of MEK inhibition alone or in combination with PI3K-mTOR pathway inhibitors in pancreatic ductal adenocarcinoma in vitro and on an innovative ex vivo fresh tumor tissue culture model

Cindy Neuzillet, Annemilaï Tijeras-Raballand, Anguraj Sadanandam, Pierre Bourgoin, Philippe Bourget, Pawan Poudel, Maria Serova, Armand De Gramont, Philippe Ruszniewski, Valérie Paradis, Eric Raymond, Jérôme Cros, Pascal Hammel
Journal: Cancer Research
Cancer Res (2016) 76 (24_Supplement): B57.
https://doi.org/10.1158/1538-7445.PANCA16-B57
Published: 14 December 2016
View article titled, Abstract B57: Effects of MEK inhibition alone or in combination with PI3K-mTOR pathway inhibitors in pancreatic ductal adenocarcinoma in vitro and on an innovative ex vivo fresh tumor tissue culture model
Journal Articles

Abstract 321: S49076, a novel kinase inhibitor of MET, AXL and FGFR, demonstrates marked in vitro and in vivo efficacy in hepatocellular carcinoma

Annemilai Tijeras-Raballand, Adrien Pasteur-Rousseau, Matthieu Martinet, Philippe Bonnin, Marc Pocard, Sébastien Banquet, Valérie Cattan, Eric Raymond, Armand de Gramont
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 321.
https://doi.org/10.1158/1538-7445.AM2016-321
Published: 15 July 2016
View article titled, Abstract 321: S49076, a novel kinase inhibitor of MET, AXL and FGFR, demonstrates marked in vitro and in vivo efficacy in hepatocellular carcinoma
Journal Articles

Abstract 3082: Biomarker-driven inhibition of MET and EGFR pathways in hepatocellular and cholangiocarcinoma models

Annemilai Tijeras-Raballand, Maria Serova, Matthieu Martinet, Nathalie Colnot, Miguel Albuquerque, Valérie Paradis, Eric Raymond, Sandrine Faivre, Armand de Gramont
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3082.
https://doi.org/10.1158/1538-7445.AM2016-3082
Published: 15 July 2016
View article titled, Abstract 3082: Biomarker-driven inhibition of MET and EGFR pathways in hepatocellular and cholangiocarcinoma models
Journal Articles

Abstract 1911: High MET and CA9 expressions define a subgroup of hepatocellular carcinoma (HCC) patients with poor prognosis candidates for MET inhibition strategy

Annemilai Tijeras-Raballand, Cindy Neuzillet, Miguel Albuquerque, Nathalie Colnot, Friedhelm Bladt, Manfred Klevesath, Christian Ihling, Hongxia Zheng, Maryse Baia, Christiane Copie-Bergman, Eric Raymond, Armand de Gramont, Valérie Paradis, Sandrine Faivre
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1911.
https://doi.org/10.1158/1538-7445.AM2015-1911
Published: 01 August 2015
View article titled, Abstract 1911: High MET and CA9 expressions define a subgroup of hepatocellular carcinoma (HCC) patients with poor prognosis candidates for MET inhibition strategy