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Eric P. Rahrmann
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Journal Articles

Sleeping Beauty Insertional Mutagenesis Reveals Important Genetic Drivers of Central Nervous System Embryonal Tumors

Pauline J. Beckmann, Jon D. Larson, Alex T. Larsson, Jason P. Ostergaard, Sandra Wagner, Eric P. Rahrmann, Ghaidan A. Shamsan, George M. Otto, Rory L. Williams, Jun Wang, Catherine Lee, Barbara R. Tschida, Paramita Das, Adrian M. Dubuc, Branden S. Moriarity, Daniel Picard, Xiaochong Wu, Fausto J. Rodriguez, Quincy Rosemarie, Ryan D. Krebs, Amy M. Molan, Addison M. Demer, Michelle M. Frees, Anthony E. Rizzardi, Stephen C. Schmechel, Charles G. Eberhart, Robert B. Jenkins, Robert J. Wechsler-Reya, David J. Odde, Annie Huang, Michael D. Taylor, Aaron L. Sarver, David A. Largaespada
Journal: Cancer Research
Series: Author Choice
Cancer Res (2019) 79 (5): 905–917.
https://doi.org/10.1158/0008-5472.CAN-18-1261
Published: 01 March 2019
View article titled, <em>Sleeping Beauty</em> Insertional Mutagenesis Reveals Important Genetic Drivers of Central Nervous System Embryonal Tumors
Open the PDF for <em>Sleeping Beauty</em> Insertional Mutagenesis Reveals Important Genetic Drivers of Central Nervous System Embryonal Tumors in another window
Includes: Supplementary data
Journal Articles

Abstract 354: Conditional inactivation of Pten and overexpression of EGFR in Schwann cells results in early high-grade peripheral nerve sheath tumor development.

Vincent W. Keng, Adrienne L. Watson, Eric P. Rahrmann, Hua Li, Barbara R. Tschida, Branden S. Moriarity, Kwangmin Choi, Tilat A. Rizvi, Margaret H. Collins, Margaret R. Wallace, Nancy Ratner, David A. Largaespada
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 354.
https://doi.org/10.1158/1538-7445.AM2013-354
Published: 15 April 2013
View article titled, Abstract 354: Conditional inactivation of <em>Pten</em> and overexpression of <em>EGFR</em> in Schwann cells results in early high-grade peripheral nerve sheath tumor development.
Journal Articles

PTEN and NF1 Inactivation in Schwann Cells Produces a Severe Phenotype in the Peripheral Nervous System That Promotes the Development and Malignant Progression of Peripheral Nerve Sheath Tumors

Vincent W. Keng, Eric P. Rahrmann, Adrienne L. Watson, Barbara R. Tschida, Christopher L. Moertel, Walter J. Jessen, Tilat A. Rizvi, Margaret H. Collins, Nancy Ratner, David A. Largaespada
Journal: Cancer Research
Cancer Res (2012) 72 (13): 3405–3413.
https://doi.org/10.1158/0008-5472.CAN-11-4092
Published: 01 July 2012
View article titled, <em>PTEN</em> and <em>NF1</em> Inactivation in Schwann Cells Produces a Severe Phenotype in the Peripheral Nervous System That Promotes the Development and Malignant Progression of Peripheral Nerve Sheath Tumors
Open the PDF for <em>PTEN</em> and <em>NF1</em> Inactivation in Schwann Cells Produces a Severe Phenotype in the Peripheral Nervous System That Promotes the Development and Malignant Progression of Peripheral Nerve Sheath Tumors in another window
Includes: Supplementary data
Journal Articles

Abstract 2199: A murine insertional mutagenesis screen to identify oncogenes and tumor suppressor genes involved in Schwann cell tumorigenesis

David A. Largaespada, Eric P. Rahrmann, Vincent W. Keng, H B. Clark, Adam J. Dupuy, Lino Tessarollo, Nancy A. Jenkins, Neal G. Copeland, Nancy Ratner
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2199.
https://doi.org/10.1158/1538-7445.AM10-2199
Published: 15 April 2010
View article titled, Abstract 2199: A murine insertional mutagenesis screen to identify oncogenes and tumor suppressor genes involved in Schwann cell tumorigenesis
Journal Articles

Identification of PDE4D as a Proliferation Promoting Factor in Prostate Cancer Using a Sleeping Beauty Transposon-Based Somatic Mutagenesis Screen

Eric P. Rahrmann, Lara S. Collier, Todd P. Knutson, Meghan E. Doyal, Sheri L. Kuslak, Laura E. Green, Rita L. Malinowski, Laura Roethe, Keiko Akagi, Michelle Waknitz, Wei Huang, David A. Largaespada, Paul C. Marker
Journal: Cancer Research
Cancer Res (2009) 69 (10): 4388–4397.
https://doi.org/10.1158/0008-5472.CAN-08-3901
Published: 15 May 2009
View article titled, Identification of <em>PDE4D</em> as a Proliferation Promoting Factor in Prostate Cancer Using a <em>Sleeping Beauty</em> Transposon-Based Somatic Mutagenesis Screen
Open the PDF for Identification of <em>PDE4D</em> as a Proliferation Promoting Factor in Prostate Cancer Using a <em>Sleeping Beauty</em> Transposon-Based Somatic Mutagenesis Screen in another window
Includes: Supplementary data