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Journal Articles

Cancers from Novel Pole-Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenesis and Immune Checkpoint Blockade

Cancer Res (2020) 80 (24): 5606–5618.

https://doi.org/10.1158/0008-5472.CAN-20-0624

Published: 15 December 2020

View article titled, Cancers from Novel Pole-Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenesis and Immune Checkpoint Blockade

Includes: Supplementary data

Journal Articles

Abstract 2789: Investigating the role of DNA methylation in pediatric choroid plexus tumors

Malgorzata Pienkowska, Sanaa Choufani, Andrei Turinsky, Diana Merino, Ana Novokmet, Michael Brudno, Rosanna Weksberg, Adam Shlien, Cynthia Hawkins, Eric Bouffet, Uri Tabori, Richard Gilbertson, David Malkin

Cancer Res (2016) 76 (14_Supplement): 2789.

https://doi.org/10.1158/1538-7445.AM2016-2789

Published: 15 July 2016

View article titled, Abstract 2789: Investigating the role of DNA methylation in pediatric choroid plexus tumors

Journal Articles

Abstract LB-179: Integrated (epi)genomic analyses identify subgroup-specific therapeutic targets in CNS rhabdoid tumors

Cancer Res (2016) 76 (14_Supplement): LB-179.

https://doi.org/10.1158/1538-7445.AM2016-LB-179

Published: 15 July 2016

View article titled, Abstract LB-179: Integrated (epi)genomic analyses identify subgroup-specific therapeutic targets in CNS rhabdoid tumors

Journal Articles

Abstract B09: DNA polymerase mutations trigger rapid onset of ultra-hypermutant malignant brain tumors in children with biallelic mismatch repair deficiency

Adam Shlien, Brittany B. Campbell, Richard de Borja, Ludmil B. Alexandrov, Daniele Merico, David Wedge, Peter Van Loo, Patrick S. Tarpey, Paul Coupland, Aaron Pollett, Tatiana Lipman, Abolfazl Heidari, Shriya Deshmukh, Moritz Gerstung, Diana Merino, Manasa Ramakrishna, Marc Remke, Roland Arnold, Gagan B. Panigrahi, Samina Afzal, Valerie Larouche, Harriet Druker, Jordan Lerner-Ellis, Matthew Mistry, Rina Dvir, Ronald Grant, Ronit Elhasid, Roula Farah, Glenn P. Taylor, Paul C. Nathan, Sarah Alexander, Shay Ben-Shachar, Nada Jabado, Steven Gallinger, Shlohmi Constantini, Peter Dirks, Annie Huang, Steven W. Scherer, Richard G. Grundy, Carol Durno, Melyssa Aronson, M Stephen Meyn, Michael D. Taylor, Zachary F. Pursell, Christopher E. Pearson, David Malkin, P Andrew Futreal, Cynthia Hawkins, Eric Bouffet, Michael D. Taylor, Peter J. Campbell, Uri Tabori

Cancer Res (2015) 75 (23_Supplement): B09.

https://doi.org/10.1158/1538-7445.BRAIN15-B09

Published: 09 December 2015

View article titled, Abstract B09: DNA polymerase mutations trigger rapid onset of ultra-hypermutant malignant brain tumors in children with biallelic mismatch repair deficiency

Journal Articles

Abstract 35: Novel genetic and clinical determinants of Constitutional Mismatch Repair Deficiency syndrome: Report from the CMMRD consortium

Cancer Res (2014) 74 (23_Supplement): 35.

https://doi.org/10.1158/1538-7445.CANSUSC14-35

Published: 12 December 2014

View article titled, Abstract 35: Novel genetic and clinical determinants of Constitutional Mismatch Repair Deficiency syndrome: Report from the CMMRD consortium

Journal Articles

Abstract A18: Uncovering molecular subgroups and a novel cancer driver, ACVR1, in diffuse intrinsic pontine gliomas

Pawel Buczkowicz, Christine Hoeman, Patricia Rakopoulos, Sanja Pajovic, Andrew Morrison, Eric Bouffet, Ute Bartels, Oren Becher, Cynthia Hawkins

Cancer Res (2014) 74 (20_Supplement): A18.

https://doi.org/10.1158/1538-7445.PEDCAN-A18

Published: 09 October 2014

View article titled, Abstract A18: Uncovering molecular subgroups and a novel cancer driver, ACVR1, in diffuse intrinsic pontine gliomas

Journal Articles

Personalizing the Treatment of Pediatric Medulloblastoma: Polo-like Kinase 1 as a Molecular Target in High-Risk Children

Cancer Res (2013) 73 (22): 6734–6744.

https://doi.org/10.1158/0008-5472.CAN-12-4331

Published: 14 November 2013

View article titled, Personalizing the Treatment of Pediatric Medulloblastoma: Polo-like Kinase 1 as a Molecular Target in High-Risk Children

Includes: Supplementary data

Journal Articles

Abstract 3552: Subgroup-specific pattern of recurrence in medulloblastoma.

Vijay Ramaswamy, Marc Remke, Eric Bouffet, David Shih, Claudia Faria, Ulrich Schüller, Sri Gururangan, Roger McLendon, Nada Jabado, Adam Fontebasso, Sandra Dunn, Joanna Triscott, Cynthia Hawkins, Uri Tabori, Kari Codispoti, Roger Packer, Stefan M. Pfister, Andrey Korshunov, Michael D. Taylor

Cancer Res (2013) 73 (8_Supplement): 3552.

https://doi.org/10.1158/1538-7445.AM2013-3552

Published: 15 April 2013

View article titled, Abstract 3552: Subgroup-specific pattern of recurrence in medulloblastoma.

Journal Articles

Abstract LB-210: Abrogation of mutant TP53 radiation resistance by lithium induced CTNNB1 (β-catenin) activation in medulloblastoma.

Nataliya Zhukova, Dianna Martin, Tatiana Lipman, Pedro Castelo-Branco, Cindy H. Zhang, Michael Fraser, Berivan Baskin, Peter Ray, Eric Bouffet, Robert Bristow, Benjamin A. Alman, Michael D. Taylor, David Malkin, Cynthia Hawkins, Uri Tabori

Cancer Res (2012) 72 (8_Supplement): LB-210.

https://doi.org/10.1158/1538-7445.AM2012-LB-210

Published: 15 April 2012

View article titled, Abstract LB-210: Abrogation of mutant TP53 radiation resistance by lithium induced CTNNB1 (β-catenin) activation in medulloblastoma.

Journal Articles

Abstract 3455: Comparison of expression profiles of pediatric high and low grade brainstem gliomas to pediatric supratentorial high grade astrocytomas

Pawel Buczkowicz, Ute Bartels, Andrew Morrison, Eric Bouffet, Uri Tabori, Cynthia Hawkins

Cancer Res (2011) 71 (8_Supplement): 3455.

https://doi.org/10.1158/1538-7445.AM2011-3455

Published: 15 April 2011

View article titled, Abstract 3455: Comparison of expression profiles of pediatric high and low grade brainstem gliomas to pediatric supratentorial high grade astrocytomas

Journal Articles

Abstract 4347: Medulloblastoma comprises four distinct diseases

Paul A. Northcott, Andrey Korshunov, Hendrik Witt, Thomas Hielscher, Charles Eberhart, Stephen Mack, Eric Bouffet, Steven C. Clifford, Cynthia Hawkins, Pim French, James T. Rutka, Stefan Pfister, Michael D. Taylor

Cancer Res (2010) 70 (8_Supplement): 4347.

https://doi.org/10.1158/1538-7445.AM10-4347

Published: 15 April 2010

View article titled, Abstract 4347: Medulloblastoma comprises four distinct diseases

Journal Articles

Abstract 4350: Clonal selection and parallel evolution during leptomeningeal dissemination of human and mouse medulloblastoma result in bicompartmental disease

Xiaochong Wu, Lara Collier, Paul Northcott, Adrian DUBUC, Charles Eberhart, Timothy Van Meter, David Zagzag, Sid Croul, Adam Dupuy, Todd E. Scheetz, Steve Scherer, Eric Bouffet, William A. Weiss, David A. David Largaespada, Michael D. Taylor

Cancer Res (2010) 70 (8_Supplement): 4350.

https://doi.org/10.1158/1538-7445.AM10-4350

Published: 15 April 2010

View article titled, Abstract 4350: Clonal selection and parallel evolution during leptomeningeal dissemination of human and mouse medulloblastoma result in bicompartmental disease

Journal Articles

Abstract 4355: The C19MC miRNA polycistron are frequent targets of gene amplification in aggressive primitive neuroectodermal brain tumors and encode oncogenic miRNAs that inhibit normal neural stem cell differentiation

Meihua Li, Kyle Lee, Yuntao Lu, Ian Clarke, David Shih, Tim Van Meter, Limei Zhou, Daniel Picard, Piergiorgio Modena, Scott Pomeroy, Ching C. Lau, Micheal D. Taylor, Eric Bouffet, James T. Rutka, Amar Gajjar, Peter B. Dirks, Cynthia E. Hawkins, Annie Huang

Cancer Res (2010) 70 (8_Supplement): 4355.

https://doi.org/10.1158/1538-7445.AM10-4355

Published: 15 April 2010

View article titled, Abstract 4355: The C19MC miRNA polycistron are frequent targets of gene amplification in aggressive primitive neuroectodermal brain tumors and encode oncogenic miRNAs that inhibit normal neural stem cell differentiation

Journal Articles

Abstract 1991: Integrated analysis of copy number alteration and RNA expression profile in pediatric diffuse intrinsic pontine glioma

Maryam Zarghooni, Ute Bartels, Eric Bouffet, Cynthia Hawkins

Cancer Res (2010) 70 (8_Supplement): 1991.

https://doi.org/10.1158/1538-7445.AM10-1991

Published: 15 April 2010

View article titled, Abstract 1991: Integrated analysis of copy number alteration and RNA expression profile in pediatric diffuse intrinsic pontine glioma

Journal Articles

Abstract 2129: Pediatric diffuse intrinsic pontine gliomas are genetically distinct from high and low grade astrocytomas

Buczkowicz Pawel, Ute Bartels, Andrew Morrison, Maryam Zarghooni, Eric Bouffet, Cynthia Hawkins

Cancer Res (2010) 70 (8_Supplement): 2129.

https://doi.org/10.1158/1538-7445.AM10-2129

Published: 15 April 2010

View article titled, Abstract 2129: Pediatric diffuse intrinsic pontine gliomas are genetically distinct from high and low grade astrocytomas

Journal Articles

Identification of a Novel c-Myc Protein Interactor, JPO2, with Transforming Activity in Medulloblastoma Cells

Annie Huang, Cynthia S.W. Ho, Romina Ponzielli, Dalia Barsyte-Lovejoy, Eric Bouffet, Daniel Picard, Cynthia E. Hawkins, Linda Z. Penn

Cancer Res (2005) 65 (13): 5607–5619.

https://doi.org/10.1158/0008-5472.CAN-05-0500

Published: 01 July 2005

View article titled, Identification of a Novel c-Myc Protein Interactor, JPO2, with Transforming Activity in Medulloblastoma Cells

Includes: Supplementary data

NARROW

Cancers from Novel Pole-Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenesis and Immune Checkpoint Blockade

Abstract 2789: Investigating the role of DNA methylation in pediatric choroid plexus tumors

Abstract LB-179: Integrated (epi)genomic analyses identify subgroup-specific therapeutic targets in CNS rhabdoid tumors

Abstract B09: DNA polymerase mutations trigger rapid onset of ultra-hypermutant malignant brain tumors in children with biallelic mismatch repair deficiency

Abstract 35: Novel genetic and clinical determinants of Constitutional Mismatch Repair Deficiency syndrome: Report from the CMMRD consortium

Abstract A18: Uncovering molecular subgroups and a novel cancer driver, ACVR1, in diffuse intrinsic pontine gliomas

Personalizing the Treatment of Pediatric Medulloblastoma: Polo-like Kinase 1 as a Molecular Target in High-Risk Children

Abstract 3552: Subgroup-specific pattern of recurrence in medulloblastoma.

Abstract LB-210: Abrogation of mutant TP53 radiation resistance by lithium induced CTNNB1 (β-catenin) activation in medulloblastoma.

Abstract 3455: Comparison of expression profiles of pediatric high and low grade brainstem gliomas to pediatric supratentorial high grade astrocytomas

Abstract 4347: Medulloblastoma comprises four distinct diseases

Abstract 4350: Clonal selection and parallel evolution during leptomeningeal dissemination of human and mouse medulloblastoma result in bicompartmental disease

Abstract 4355: The C19MC miRNA polycistron are frequent targets of gene amplification in aggressive primitive neuroectodermal brain tumors and encode oncogenic miRNAs that inhibit normal neural stem cell differentiation

Abstract 1991: Integrated analysis of copy number alteration and RNA expression profile in pediatric diffuse intrinsic pontine glioma

Abstract 2129: Pediatric diffuse intrinsic pontine gliomas are genetically distinct from high and low grade astrocytomas

Identification of a Novel c-Myc Protein Interactor, JPO2, with Transforming Activity in Medulloblastoma Cells

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