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Journal Articles

Abstract 6892: Ribonucleotide reductase is a potential therapeutic target in colorectal cancer

Federica Invrea, Consalvo Petti, Claudio Isella, Enzo Medico

Cancer Res (2025) 85 (8_Supplement_1): 6892.

https://doi.org/10.1158/1538-7445.AM2025-6892

Published: 21 April 2025

View articletitled, Abstract 6892: Ribonucleotide reductase is a potential therapeutic target in colorectal cancer

Journal Articles

Abstract 3175: Exploring the potential of CEA-CAR-NK cells in colorectal cancer

Alice D'Andrea, Marco Cortese, Enzo Medico

Cancer Res (2025) 85 (8_Supplement_1): 3175.

https://doi.org/10.1158/1538-7445.AM2025-3175

Published: 21 April 2025

View articletitled, Abstract 3175: Exploring the potential of CEA-CAR-NK cells in colorectal cancer

Journal Articles

Abstract LB069: Repurposing anti-mesothelin CAR-NK immunotherapy against colorectal cancer

Erica Torchiaro, Marco Cortese, Alice D'Andrea, Consalvo Petti, Enzo Medico

Cancer Res (2024) 84 (7_Supplement): LB069.

https://doi.org/10.1158/1538-7445.AM2024-LB069

Published: 05 April 2024

View articletitled, Abstract LB069: Repurposing anti-mesothelin CAR-NK immunotherapy against colorectal cancer

Journal Articles

Abstract 3998: Preclinical efficacy of a synthetic Notch-based combinatorial immunotherapy against colorectal cancer with HER2 amplification

Marco Cortese, Erica Torchiaro, Alice D'Andrea, Consalvo Petti, Federica Invrea, Letizia Franco, Chiara Donini, Valeria Leuci, Simonetta M. Leto, Valentina Vurchio, Francesca Cottino, Claudio Isella, Sabrina Arena, Elisa Vigna, Andrea Bertotti, Livio Trusolino, Dario Sangiolo, Enzo Medico

Cancer Res (2024) 84 (6_Supplement): 3998.

https://doi.org/10.1158/1538-7445.AM2024-3998

Published: 22 March 2024

View articletitled, Abstract 3998: Preclinical efficacy of a synthetic Notch-based combinatorial immunotherapy against colorectal cancer with HER2 amplification

Journal Articles

Abstract LB091: Design, characterization and preclinical validation of a combinatorial CAR-based immunotherapy against colorectal cancer with HER2 amplification

Marco Cortese, Erica Torchiaro, Federica Invrea, Consalvo Petti, Alice D'Andrea, Sabrina Arena, Enzo Medico

Cancer Res (2023) 83 (8_Supplement): LB091.

https://doi.org/10.1158/1538-7445.AM2023-LB091

Published: 14 April 2023

View articletitled, Abstract LB091: Design, characterization and preclinical validation of a combinatorial CAR-based immunotherapy against colorectal cancer with HER2 amplification

Journal Articles

Abstract B022: The NEDD8 pathway as a therapeutic target in HER2-amplified colorectal cancer

Federica Invrea, Alessandro Carugo, Consalvo Petti, Giulio Draetta, Enzo Medico

Cancer Res (2022) 82 (23_Supplement_1): B022.

https://doi.org/10.1158/1538-7445.CRC22-B022

Published: 01 December 2022

View articletitled, Abstract B022: The NEDD8 pathway as a therapeutic target in HER2-amplified colorectal cancer

Journal Articles

Abstract 2611: The NEDD8 pathway as a therapeutic target in HER2-amplified colorectal cancer

Federica Invrea, Alessandro Carugo, Sabrina Arena, Alberto Bardelli, Giulio F. Draetta, Enzo Medico

Cancer Res (2022) 82 (12_Supplement): 2611.

https://doi.org/10.1158/1538-7445.AM2022-2611

Published: 15 June 2022

View articletitled, Abstract 2611: The NEDD8 pathway as a therapeutic target in HER2-amplified colorectal cancer

Journal Articles

Abstract 1201: GenomeCruzer: A tool for interactive 3D visualization and analysis of multidimensional cancer omics

Claudio Isella, Riccardo Corsi, Jamal Elhasnaoui, Andrea Bertotti, Luca Vezzadini, Enzo Medico

Cancer Res (2022) 82 (12_Supplement): 1201.

https://doi.org/10.1158/1538-7445.AM2022-1201

Published: 15 June 2022

View articletitled, Abstract 1201: GenomeCruzer: A tool for interactive 3D visualization and analysis of multidimensional cancer omics

Journal Articles

Abstract 1118: Absence of mouse-specific tumor evolution in patient-derived cancer xenografts

Cancer Res (2020) 80 (16_Supplement): 1118.

https://doi.org/10.1158/1538-7445.AM2020-1118

Published: 15 August 2020

View articletitled, Abstract 1118: Absence of mouse-specific tumor evolution in patient-derived cancer xenografts

Journal Articles

Abstract 1685: The EurOPDX Research Infrastructure: Supporting European and worldwide cancer research with patient-derived xenografts

Cancer Res (2020) 80 (16_Supplement): 1685.

https://doi.org/10.1158/1538-7445.AM2020-1685

Published: 15 August 2020

View articletitled, Abstract 1685: The EurOPDX Research Infrastructure: Supporting European and worldwide cancer research with patient-derived xenografts

Journal Articles

Abstract 1935: The NEDD8 and EGFR pathways are independent therapeutic targets in colorectal cancer

Federica Invrea, Alessandro Carugo, Consalvo Petti, Cristopher Bristow, Michael Peoples, Carlotta Cancelliere, Alessia Corrado, Alberto Bardelli, Claudio Isella, Giulio F. Draetta, Enzo Medico

Cancer Res (2020) 80 (16_Supplement): 1935.

https://doi.org/10.1158/1538-7445.AM2020-1935

Published: 15 August 2020

View articletitled, Abstract 1935: The NEDD8 and EGFR pathways are independent therapeutic targets in colorectal cancer

Journal Articles

Abstract 1673: Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

Cancer Res (2020) 80 (16_Supplement): 1673.

https://doi.org/10.1158/1538-7445.AM2020-1673

Published: 15 August 2020

View articletitled, Abstract 1673: Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

Journal Articles

Abstract CT263: Post-surgical liquid biopsy-guided treatment of stage III and high-risk stage II colon cancer patients: The PEGASUS trial

Cancer Res (2020) 80 (16_Supplement): CT263.

https://doi.org/10.1158/1538-7445.AM2020-CT263

Published: 15 August 2020

View articletitled, Abstract CT263: Post-surgical liquid biopsy-guided treatment of stage III and high-risk stage II colon cancer patients: The PEGASUS trial

Journal Articles

A Comprehensive PDX Gastric Cancer Collection Captures Cancer Cell–Intrinsic Transcriptional MSI Traits

Simona Corso, Claudio Isella, Sara E. Bellomo, Maria Apicella, Stefania Durando, Cristina Migliore, Stefano Ughetto, Laura D’Errico, Silvia Menegon, Daniel Moya-Rull, Marilisa Cargnelutti, Tânia Capelôa, Daniela Conticelli, Jessica Giordano, Tiziana Venesio, Antonella Balsamo, Caterina Marchiò, Maurizio Degiuli, Rossella Reddavid, Uberto Fumagalli, Stefano De Pascale, Giovanni Sgroi, Emanuele Rausa, Gian Luca Baiocchi, Sarah Molfino, Filippo Pietrantonio, Federica Morano, Salvatore Siena, Andrea Sartore-Bianchi, Maria Bencivenga, Valentina Mengardo, Riccardo Rosati, Daniele Marrelli, Paolo Morgagni, Stefano Rausei, Giovanni Pallabazzer, Michele De Simone, Dario Ribero, Silvia Marsoni, Antonino Sottile, Enzo Medico, Paola Cassoni, Anna Sapino, Eirini Pectasides, Aaron R. Thorner, Anwesha Nag, Samantha D. Drinan, Bruce M. Wollison, Adam J. Bass, Silvia Giordano

Cancer Res (2019) 79 (22): 5884–5896.

https://doi.org/10.1158/0008-5472.CAN-19-1166

Published: 15 November 2019

View articletitled, A Comprehensive PDX Gastric Cancer Collection Captures Cancer Cell–Intrinsic Transcriptional MSI Traits

Includes: Supplementary data

Journal Articles

Abstract CT214: AlfaOmega- a master protocol empowering precision research in colorectal cancer

Luca Lazzari, Paolo Luraghi, Nabil Amirouchene-Angelozzi, Andrea Bertotti, Enzo Medico, Federica Di Nicolantonio, Fabrizio d'Adda di Fagagna, Sergio Abrignani, Daniele Regge, Anna Sapino, Emanuela Bonoldi, Angelo Vanzulli, Vittorina Zagonel, Filippo de Braud, Livio Trusolino, Alberto Bardelli, Salvatore Siena, Silvia Marsoni

Cancer Res (2019) 79 (13_Supplement): CT214.

https://doi.org/10.1158/1538-7445.AM2019-CT214

Published: 01 July 2019

View articletitled, Abstract CT214: AlfaOmega- a master protocol empowering precision research in colorectal cancer

Journal Articles

Abstract LB-299: A comprehensive platform of patient-derived xenografts and matched cell lines mirrors the genomic landscape of colorectal cancer

Luca Lazzari, Giorgio Corti, Claudio Isella, Monica Montone, Pamela Arcella, Eugenia Zanella, Luca Novara, Fabiane Barbosa, Andrea Cassingena, Carlotta Cancelliere, Enzo Medico, Andrea Sartore-Bianchi, Salvatore Siena, Andrea Bertotti, Livio Trusolino, Federica Di Nicolantonio, Michael Linnebacher, Alberto Bardelli, Sabrina Arena

Cancer Res (2019) 79 (13_Supplement): LB-299.

https://doi.org/10.1158/1538-7445.AM2019-LB-299

Published: 01 July 2019

View articletitled, Abstract LB-299: A comprehensive platform of patient-derived xenografts and matched cell lines mirrors the genomic landscape of colorectal cancer

Journal Articles

Abstract 4737: Case report: Preclinical testing of NEDD8 and proteasome inhibitors for a treatment-refractory, metastatic high-grade mucinous colorectal cancer

Erica Torchiaro, Consalvo Petti, Claudio Isella, Enzo Medico

Cancer Res (2019) 79 (13_Supplement): 4737.

https://doi.org/10.1158/1538-7445.AM2019-4737

Published: 01 July 2019

View articletitled, Abstract 4737: Case report: Preclinical testing of NEDD8 and proteasome inhibitors for a treatment-refractory, metastatic high-grade mucinous colorectal cancer

Journal Articles

Abstract 5365: Prospective patient stratification into robust cancer-cell intrinsic subtypes from colorectal cancer biopsies

Matthew Alderdice, Susan D. Richman, Simon Gollins, Peter Stewart, Chris Hurt, Richard Adams, Amy M. McCorry, Aideen Roddy, Dale Vimalachandran, Claudio Isella, Enzo Medico, Tim Maughan, Darrgh G. McArt, Mark Lawler, Philip D. Dunne

Cancer Res (2018) 78 (13_Supplement): 5365.

https://doi.org/10.1158/1538-7445.AM2018-5365

Published: 01 July 2018

View articletitled, Abstract 5365: Prospective patient stratification into robust cancer-cell intrinsic subtypes from colorectal cancer biopsies

Journal Articles

Abstract 4038: A functional genomics approach to the identification of genes involved in resistance to Oxaliplatin in colorectal cancer

Federica Invrea, Francesca Cavicchioli, Consalvo Petti, Rosalia Russo, Claudio Isella, Enzo Medico

Cancer Res (2018) 78 (13_Supplement): 4038.

https://doi.org/10.1158/1538-7445.AM2018-4038

Published: 01 July 2018

View articletitled, Abstract 4038: A functional genomics approach to the identification of genes involved in resistance to Oxaliplatin in colorectal cancer

Journal Articles

Abstract 3403: Conservation of colorectal cancer cell-intrisinc transcriptional traits in paired in vitro / in vivo cellular models

Claudio Isella, Consalvo Petti, Carlotta Cancelliere, Daniela Cantarella, Roberta Porporato, Livio Trusolino, Andrea Bertotti, Alberto Bardelli, Enzo Medico

Cancer Res (2018) 78 (13_Supplement): 3403.

https://doi.org/10.1158/1538-7445.AM2018-3403

Published: 01 July 2018

View articletitled, Abstract 3403: Conservation of colorectal cancer cell-intrisinc transcriptional traits in paired in vitro / in vivo cellular models

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Abstract 6892: Ribonucleotide reductase is a potential therapeutic target in colorectal cancer

Abstract 3175: Exploring the potential of CEA-CAR-NK cells in colorectal cancer

Abstract LB069: Repurposing anti-mesothelin CAR-NK immunotherapy against colorectal cancer

Abstract 3998: Preclinical efficacy of a synthetic Notch-based combinatorial immunotherapy against colorectal cancer with HER2 amplification

Abstract LB091: Design, characterization and preclinical validation of a combinatorial CAR-based immunotherapy against colorectal cancer with HER2 amplification

Abstract B022: The NEDD8 pathway as a therapeutic target in HER2-amplified colorectal cancer

Abstract 2611: The NEDD8 pathway as a therapeutic target in HER2-amplified colorectal cancer

Abstract 1201: GenomeCruzer: A tool for interactive 3D visualization and analysis of multidimensional cancer omics

Abstract 1118: Absence of mouse-specific tumor evolution in patient-derived cancer xenografts

Abstract 1685: The EurOPDX Research Infrastructure: Supporting European and worldwide cancer research with patient-derived xenografts

Abstract 1935: The NEDD8 and EGFR pathways are independent therapeutic targets in colorectal cancer

Abstract 1673: Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

Abstract CT263: Post-surgical liquid biopsy-guided treatment of stage III and high-risk stage II colon cancer patients: The PEGASUS trial

A Comprehensive PDX Gastric Cancer Collection Captures Cancer Cell–Intrinsic Transcriptional MSI Traits

Abstract CT214: AlfaOmega- a master protocol empowering precision research in colorectal cancer

Abstract LB-299: A comprehensive platform of patient-derived xenografts and matched cell lines mirrors the genomic landscape of colorectal cancer

Abstract 4737: Case report: Preclinical testing of NEDD8 and proteasome inhibitors for a treatment-refractory, metastatic high-grade mucinous colorectal cancer

Abstract 5365: Prospective patient stratification into robust cancer-cell intrinsic subtypes from colorectal cancer biopsies

Abstract 4038: A functional genomics approach to the identification of genes involved in resistance to Oxaliplatin in colorectal cancer

Abstract 3403: Conservation of colorectal cancer cell-intrisinc transcriptional traits in paired in vitro / in vivo cellular models

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