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Journal Articles

Abstract CT150: A first-in-human phase I study of the OX40 agonist GSK3174998 (GSK998) +/- pembrolizumab in patients (Pts) with selected advanced solid tumors (ENGAGE-1)

Cancer Res (2020) 80 (16_Supplement): CT150.

https://doi.org/10.1158/1538-7445.AM2020-CT150

Published: 15 August 2020

View article titled, Abstract CT150: A first-in-human phase I study of the OX40 agonist GSK3174998 (GSK998) +/- pembrolizumab in patients (Pts) with selected advanced solid tumors (ENGAGE-1)

Journal Articles

Abstract CT139: Durability of responses to the combination of SD-101 and pembrolizumab in advanced metastatic melanoma: Results of a phase Ib, multicenter study

Antoni Ribas, Theresa Medina, Shivaani Kummar, Asim Amin, Joseph J. Drabick, Minal Barve, Gregory Daniels, Deborah L. Wong, Emmett V. Schmidt, Abraham C. Leung, Robert Janssen

Cancer Res (2018) 78 (13_Supplement): CT139.

https://doi.org/10.1158/1538-7445.AM2018-CT139

Published: 01 July 2018

View article titled, Abstract CT139: Durability of responses to the combination of SD-101 and pembrolizumab in advanced metastatic melanoma: Results of a phase Ib, multicenter study

Journal Articles

Abstract CT098: Phase Ib/II, open label, multicenter study of intratumoral SD-101 in combination with pembrolizumab in anti-PD-1 treatment naïve patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC)

Ezra Cohen, Sarwan Bishnoi, Douglas E. Laux, Deborah Wong, Asim Amin, Lisle Nabell, Emmett V. Schmidt, Biao Xing, Abraham C. Leung, Robert Janssen

Cancer Res (2018) 78 (13_Supplement): CT098.

https://doi.org/10.1158/1538-7445.AM2018-CT098

Published: 01 July 2018

View article titled, Abstract CT098: Phase Ib/II, open label, multicenter study of intratumoral SD-101 in combination with pembrolizumab in anti-PD-1 treatment naïve patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC)

Journal Articles

Abstract 1677: Preclinical activity of Vintafolide/MK-8109 monotherapy and in combination with standard of care therapy in triple-negative breast cancer models

Brian B. Haines, Jennifer O'Neil, Marlene C. Hinton, Christopher Ware, Tammie C. Yeh, Tianxiao Sun, Kristen L. Picard, Theresa Zhang, Emmett V. Schmidt, Isabelle Dussault

Cancer Res (2014) 74 (19_Supplement): 1677.

https://doi.org/10.1158/1538-7445.AM2014-1677

Published: 01 October 2014

View article titled, Abstract 1677: Preclinical activity of Vintafolide/MK-8109 monotherapy and in combination with standard of care therapy in triple-negative breast cancer models

Journal Articles

The Integrin α_vβ_3-5 Ligand MFG-E8 Is a p63/p73 Target Gene in Triple-Negative Breast Cancers but Exhibits Suppressive Functions in ER⁺ and erbB2⁺ Breast Cancers

Chuanwei Yang, Tetsu Hayashida, Nicole Forster, Cuiqi Li, Dejun Shen, Shyamala Maheswaran, Li Chen, Karen S. Anderson, Leif W. Ellisen, Dennis Sgroi, Emmett V. Schmidt

Cancer Res (2011) 71 (3): 937–945.

https://doi.org/10.1158/0008-5472.CAN-10-1471

Published: 01 February 2011

View article titled, The Integrin αvβ3-5 Ligand MFG-E8 Is a p63/p73 Target Gene in Triple-Negative Breast Cancers but Exhibits Suppressive Functions in ER+ and erbB2+ Breast Cancers

Includes: Supplementary data

Journal Articles

Abstract 1469: Cyclin D1 plays a critical role in the response of mammary gland to estrogen and progesterone by regulating progesterone receptor expression

Chuanwei Yang, Li Chen, Cuiqi Li, Mary C. Lynch, Emmett V. Schmidt

Cancer Res (2010) 70 (8_Supplement): 1469.

https://doi.org/10.1158/1538-7445.AM10-1469

Published: 15 April 2010

View article titled, Abstract 1469: Cyclin D1 plays a critical role in the response of mammary gland to estrogen and progesterone by regulating progesterone receptor expression

Journal Articles

Abstract 4745: A whole genome association study and identification of a locus for histiocytic sarcoma in the flat-coated retriever

Abigail L. Shearin, Emmett V. Schmidt, Heidi G. Parker, Cathryn S. Mellersh, Matthew Breen, Elaine A. Ostrander

Cancer Res (2010) 70 (8_Supplement): 4745.

https://doi.org/10.1158/1538-7445.AM10-4745

Published: 15 April 2010

View article titled, Abstract 4745: A whole genome association study and identification of a locus for histiocytic sarcoma in the flat-coated retriever

Journal Articles

c-myc Repression of TSC2 Contributes to Control of Translation Initiation and Myc-Induced Transformation

Michael J. Ravitz, Li Chen, Mary Lynch, Emmett V. Schmidt

Cancer Res (2007) 67 (23): 11209–11217.

https://doi.org/10.1158/0008-5472.CAN-06-4351

Published: 03 December 2007

View article titled, c-myc Repression of TSC2 Contributes to Control of Translation Initiation and Myc-Induced Transformation

Includes: Supplementary data

Journal Articles

Heat Shock Protein B8, a Cyclin-Dependent Kinase–Independent Cyclin D1 Target Gene, Contributes to Its Effects on Radiation Sensitivity

Sally Trent, Chuanwei Yang, Cuiqi Li, Mary Lynch, Emmett V. Schmidt

Cancer Res (2007) 67 (22): 10774–10781.

https://doi.org/10.1158/0008-5472.CAN-07-1475

Published: 15 November 2007

View article titled, Heat Shock Protein B8, a Cyclin-Dependent Kinase–Independent Cyclin D1 Target Gene, Contributes to Its Effects on Radiation Sensitivity

Includes: Supplementary data

Journal Articles

Identification of Cyclin D1– and Estrogen-Regulated Genes Contributing to Breast Carcinogenesis and Progression

Chuanwei Yang, Sally Trent, Viviana Ionescu-Tiba, Lan Lan, Toshi Shioda, Dennis Sgroi, Emmett V. Schmidt

Cancer Res (2006) 66 (24): 11649–11658.

https://doi.org/10.1158/0008-5472.CAN-06-1645

Published: 18 December 2006

View article titled, Identification of Cyclin D1– and Estrogen-Regulated Genes Contributing to Breast Carcinogenesis and Progression

Includes: Supplementary data

Journal Articles

Candidate ER regulated genes that may mediate cyclin D1 induced breast tumorigenesis and cancer progression

Chuanwei Yang, Sally Trent, Viviana Ionescu-Tiba, Dennis Sgroi, Lan Lan, Robert D. Cardiff, Emmett V. Schmidt

Cancer Res (2006) 66 (8_Supplement): 350.

Published: 15 April 2006

View article titled, Candidate ER regulated genes that may mediate cyclin D1 induced breast tumorigenesis and cancer progression

Journal Articles

Mammary Tumorigenesis following Transgenic Expression of a Dominant Negative CHK2 Mutant

Eunice L. Kwak, Sang Kim, Jianmin Zhang, Robert D. Cardiff, Emmett V. Schmidt, Daniel A. Haber

Cancer Res (2006) 66 (4): 1923–1928.

https://doi.org/10.1158/0008-5472.CAN-05-1237

Published: 17 February 2006

View article titled, Mammary Tumorigenesis following Transgenic Expression of a Dominant Negative CHK2 Mutant

Journal Articles

Identification of estrogen-regulated genes that mediate erbB2 and cyclin D1 induced breast cancer

Chuanwei Yang, Sally Trent, Michael Overholtzer, Dennis Sgroi, Emmett V. Schmidt

Cancer Res (2005) 65 (9_Supplement): 1246.

Published: 01 May 2005

View article titled, Identification of estrogen-regulated genes that mediate erbB2 and cyclin D1 induced breast cancer

Journal Articles

Identification of estrogen-regulated genes that mediate erbB2 and cyclin D1 induced breast carcinogenesis.

Chuanwei Yang, Sally Trent, Dennis Sgroi, Viviana Ionescu-Tiba, Emmett V. Schmidt

Cancer Res (2004) 64 (7_Supplement): 522.

Published: 01 April 2004

View article titled, Identification of estrogen-regulated genes that mediate erbB2 and cyclin D1 induced breast carcinogenesis.

Journal Articles

Epidermal Growth Factor Receptor Expression Is a Candidate Target of the Synergistic Combination of Trastuzumab and Flavopiridol in Breast Cancer

Rita Nahta, Sally Trent, Chuanwei Yang, Emmett V. Schmidt

Cancer Res (2003) 63 (13): 3626–3631.

Published: 01 July 2003

View article titled, Epidermal Growth Factor Receptor Expression Is a Candidate Target of the Synergistic Combination of Trastuzumab and Flavopiridol in Breast Cancer

Journal Articles

Rate-limiting Effects of Cyclin D1 in Transformation by ErbB2 Predicts Synergy between Herceptin and Flavopiridol

Rita Nahta, J. Dirk Iglehart, Bettina Kempkes, Emmett V. Schmidt

Cancer Res (2002) 62 (8): 2267–2271.

Published: 01 April 2002

View article titled, Rate-limiting Effects of Cyclin D1 in Transformation by ErbB2 Predicts Synergy between Herceptin and Flavopiridol

Journal Articles

Regulation of Cyclin D1 and p16^INK4A Is Critical for Growth Arrest during Mammary Involution

Michele Gadd, Carmen Pisc, John Branda, Viviana Ionescu-Tiba, Zeljko Nikolic, Chuanwei Yang, Timothy Wang, Gregory M. Shackleford, Robert D. Cardiff, Emmett V. Schmidt

Cancer Res (2001) 61 (24): 8811–8819.

Published: 01 December 2001

View article titled, Regulation of Cyclin D1 and p16INK4A Is Critical for Growth Arrest during Mammary Involution

NARROW

Abstract CT150: A first-in-human phase I study of the OX40 agonist GSK3174998 (GSK998) +/- pembrolizumab in patients (Pts) with selected advanced solid tumors (ENGAGE-1)

Abstract CT139: Durability of responses to the combination of SD-101 and pembrolizumab in advanced metastatic melanoma: Results of a phase Ib, multicenter study

Abstract CT098: Phase Ib/II, open label, multicenter study of intratumoral SD-101 in combination with pembrolizumab in anti-PD-1 treatment naïve patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC)

Abstract 1677: Preclinical activity of Vintafolide/MK-8109 monotherapy and in combination with standard of care therapy in triple-negative breast cancer models

The Integrin α_vβ_3-5 Ligand MFG-E8 Is a p63/p73 Target Gene in Triple-Negative Breast Cancers but Exhibits Suppressive Functions in ER⁺ and erbB2⁺ Breast Cancers

Abstract 1469: Cyclin D1 plays a critical role in the response of mammary gland to estrogen and progesterone by regulating progesterone receptor expression

Abstract 4745: A whole genome association study and identification of a locus for histiocytic sarcoma in the flat-coated retriever

c-myc Repression of TSC2 Contributes to Control of Translation Initiation and Myc-Induced Transformation

Heat Shock Protein B8, a Cyclin-Dependent Kinase–Independent Cyclin D1 Target Gene, Contributes to Its Effects on Radiation Sensitivity

Identification of Cyclin D1– and Estrogen-Regulated Genes Contributing to Breast Carcinogenesis and Progression

Candidate ER regulated genes that may mediate cyclin D1 induced breast tumorigenesis and cancer progression

Mammary Tumorigenesis following Transgenic Expression of a Dominant Negative CHK2 Mutant

Identification of estrogen-regulated genes that mediate erbB2 and cyclin D1 induced breast cancer

Identification of estrogen-regulated genes that mediate erbB2 and cyclin D1 induced breast carcinogenesis.

Epidermal Growth Factor Receptor Expression Is a Candidate Target of the Synergistic Combination of Trastuzumab and Flavopiridol in Breast Cancer

Rate-limiting Effects of Cyclin D1 in Transformation by ErbB2 Predicts Synergy between Herceptin and Flavopiridol

Regulation of Cyclin D1 and p16^INK4A Is Critical for Growth Arrest during Mammary Involution

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