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Emanuele Valtorta
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Journal Articles

Abstract 6262: Emergence of tumor mismatch repair deficiency and increased mutational burden in blood and tissue of metastatic colorectal cancer patients treated with temozolomide

Giovanni Crisafulli, Andrea Sartore-Bianchi, Luca Lazzari, Filippo Pietrantonio, Alessio Amatu, Marco Macagno, Ludovic Barault, Andrea Cassingena, Alice Bartolini, Paolo Luraghi, Gianluca Mauri, Paolo Battuello, Nicola Personemi, Valeria Pessei, Pietro Paolo Vitiello, Federica Tosi, Laura Idotta, Emanuele Valtorta, Emanuela Bonoldi, Giovanni Germano, Federica Di Nicolantonio, Silvia Marsoni, Salvatore Siena, Alberto Bardelli
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6262.
https://doi.org/10.1158/1538-7445.AM2022-6262
Published: 15 June 2022
View article titled, Abstract 6262: Emergence of tumor mismatch repair deficiency and increased mutational burden in blood and tissue of metastatic colorectal cancer patients treated with temozolomide
Journal Articles

Abstract 5419: A unique pattern of heterogeneous MMR protein expression in colorectal cancer unveils different degrees of tumor mutational burden and distinct tumor microenvironment features

Enrico Berrino, Maria Costanza Aquilano, Emanuele Valtorta, Vito Amodio, Giovanni Germano, Marco Gusmini, Ivana Sarotto, Anna Sapino, Silvia Marsoni, Andrea Sartore-Bianchi, Alberto Bardelli, Salvatore Siena, Emanuela Bonoldi, Caterina Marchio
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5419.
https://doi.org/10.1158/1538-7445.AM2022-5419
Published: 15 June 2022
View article titled, Abstract 5419: A unique pattern of heterogeneous MMR protein expression in colorectal cancer unveils different degrees of tumor mutational burden and distinct tumor microenvironment features
Journal Articles

Abstract CT215: Pharmacological inactivation of DNA repair to improve response to immunotherapy: The Arethusa trial in metastatic colorectal cancer

Silvia Marsoni, Giovanni Germano, Andrea Sartore Bianchi, Filippo Pietrantonio, Nicola Personeni, Alessio Amatu, Emanuela Bonoldi, Emanuele Valtorta, Ludovic Barault, Federica Di Nicolantonio, Filippo de Braud, Lorenza Rimassa, Armando Santoro, Silvia Ghezzi, Andrea Cassingena, Giovanna Marrapese, Loredana Lupica, Giulia Siravegna, Giuseppe Rospo, Cosimo Martino, Luca Lazzari, Paolo Luraghi, Nabil Amirouchene-Angelozzi, Alberto Bardelli, Salvatore Siena
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): CT215.
https://doi.org/10.1158/1538-7445.AM2019-CT215
Published: 01 July 2019
View article titled, Abstract CT215: Pharmacological inactivation of DNA repair to improve response to immunotherapy: The Arethusa trial in metastatic colorectal cancer
Journal Articles

Abstract 2848: Radiographic and genomic evolution of individual metastases during HER2 blockade in colorectal cancer

Giulia Siravegna, Luca Lazzari, Andrea Sartore-Bianchi, Giovanni Crisafulli, Benedetta Mussolin, Andrea Cassingena, Cosimo Martino, Richard Lanman, Rebecca Nagy, Giorgio Corti, Alice Bartolini, Pamela Arcella, Monica Montone, Francesca Lodi, Alice Vanzati, Emanuele Valtorta, Giovanni Cappello, Andrea Bertotti, Sara Lonardi, Vittorina Zagonel, Francesco Leone, Mariangela Russo, Antonella Balsamo, Mauro Truini, Federica Di Nicolantonio, Alessio Amatu, Erica Bonazzina, Silvia Ghezzi, Daniele Regge, Angelo Vanzulli, Livio Trusolino, Salvatore Siena, Silvia Marsoni, Alberto Bardelli
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2848.
https://doi.org/10.1158/1538-7445.AM2018-2848
Published: 01 July 2018
View article titled, Abstract 2848: Radiographic and genomic evolution of individual metastases during HER2 blockade in colorectal cancer
Journal Articles

Abstract CT005: Final results of the HERACLES trial in HER2-amplified colorectal cancer

Salvatore Siena, Andrea Sartore-Bianchi, Livio Trusolino, Cosimo Martino, Katia Bencardino, Sara Lonardi, Vittorina Zagonel, Francesco Leone, Erika Martinelli, Fortunato Ciardiello, Patrizia Racca, Alessio Amatu, Laura Palmeri, Emanuele Valtorta, Silvia Ghezzi, Angelo Vanzulli, Daniele Regge, Silvio Veronese, Alberto Bardelli, Silvia Marsoni
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): CT005.
https://doi.org/10.1158/1538-7445.AM2017-CT005
Published: 01 July 2017
View article titled, Abstract CT005: Final results of the HERACLES trial in HER2-amplified colorectal cancer
Journal Articles

Abstract 2913: Emergence of RAS or EGFR mutant clones affects duration of response to EGFR blockade in colorectal cancers

Sabrina Arena, Beth Van Emburgh, Giulia Siravegna, Luca Lazzari, Giovanni Crisafulli, Giorgio Corti, Benedetta Mussolin, Federica Baldi, Michela Buscarino, Alice Bartolini, Emanuele Valtorta, Joana Vidal, Beatriz Bellosillo, Giovanni Germano, Filippo Pietrantonio, Agostino Ponzetti, Joan Albanell, Salvatore Siena, Andrea Sartore-Bianchi, Federica Di Nicolantonio, Clara Montagut, Alberto Bardelli
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2913.
https://doi.org/10.1158/1538-7445.AM2017-2913
Published: 01 July 2017
View article titled, Abstract 2913: Emergence of <em>RAS</em> or <em>EGFR</em> mutant clones affects duration of response to EGFR blockade in colorectal cancers
Journal Articles

Molecular Landscape of Acquired Resistance to Targeted Therapy Combinations in BRAF-Mutant Colorectal Cancer

Daniele Oddo, Erin M. Sennott, Ludovic Barault, Emanuele Valtorta, Sabrina Arena, Andrea Cassingena, Genny Filiciotto, Giulia Marzolla, Elena Elez, Robin M.J.M. van Geel, Alice Bartolini, Giovanni Crisafulli, Valentina Boscaro, Jason T. Godfrey, Michela Buscarino, Carlotta Cancelliere, Michael Linnebacher, Giorgio Corti, Mauro Truini, Giulia Siravegna, Julieta Grasselli, Margherita Gallicchio, René Bernards, Jan H.M. Schellens, Josep Tabernero, Jeffrey A. Engelman, Andrea Sartore-Bianchi, Alberto Bardelli, Salvatore Siena, Ryan B. Corcoran, Federica Di Nicolantonio
Journal: Cancer Research
Cancer Res (2016) 76 (15): 4504–4515.
https://doi.org/10.1158/0008-5472.CAN-16-0396
Published: 31 July 2016
View article titled, Molecular Landscape of Acquired Resistance to Targeted Therapy Combinations in <em>BRAF</em>-Mutant Colorectal Cancer
Open the PDF for Molecular Landscape of Acquired Resistance to Targeted Therapy Combinations in <em>BRAF</em>-Mutant Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 878: Tumor heterogeneity and lesion-specific response to targeted therapy in colorectal cancer

Mariangela Russo, Giulia Siravegna, Lawrence S. Blaszkowsky, Giorgio Corti, Giovanni Crisafulli, Leanne G. Ahronian, Benedetta Mussolin, Eunice L. Kwak, Michela Buscarino, Luca Lazzari, Emanuele Valtorta, Mauro Truini, Nicholas A. Jessop, Hayley E. Robinson, Theodore S. Hong, Mari Mino-Kenudson, Federica Di Nicolantonio, Ashraf Thabet, Andrea Sartore-Bianchi, Salvatore Siena, A John Iafrate, Ryan B. Corcoran, Alberto Bardelli
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 878.
https://doi.org/10.1158/1538-7445.AM2016-878
Published: 15 July 2016
View article titled, Abstract 878: Tumor heterogeneity and lesion-specific response to targeted therapy in colorectal cancer
Journal Articles

Abstract CT082: Pertuzumab and trastuzumab-emtansine in HER2-positive colorectal cancer: the HERACLES B trial

Livio Trusolino, Andrea Bertotti, Sara Lonardi, Andrea Sartore-Bianchi, Cosimo Martino, Francesca Cottino, Valentina Vurchio, Emanuele Valtorta, Calogero Lauricella, Daniele Regge, Angelo Vanzulli, Vittorina Zagonel, Francesco Leone, Patrizia Racca, Fortunato Ciardiello, Andrea Ardizzoni, Silvia Marsoni, Salvatore Siena
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): CT082.
https://doi.org/10.1158/1538-7445.AM2016-CT082
Published: 15 July 2016
View article titled, Abstract CT082: Pertuzumab and trastuzumab-emtansine in HER2-positive colorectal cancer: the HERACLES B trial
Journal Articles

Abstract 916: The molecular landscape of colorectal cancer cell lines unveils clinically actionable targets

Mariangela Russo, Gabriele Picco, Carlotta Cancelliere, Giorgio Corti, Emanuele Valtorta, Silvio Veronese, Marco Beccuti, Francesca Cordero, Federica Di Nicolantonio, Enzo Medico, Alberto Bardelli
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 916.
https://doi.org/10.1158/1538-7445.AM2015-916
Published: 01 August 2015
View article titled, Abstract 916: The molecular landscape of colorectal cancer cell lines unveils clinically actionable targets
Journal Articles

The High Mobility Group A2 Gene Is Amplified and Overexpressed in Human Prolactinomas

Palma Finelli, Giovanna Maria Pierantoni, Daniela Giardino, Marco Losa, Ornella Rodeschini, Monica Fedele, Emanuele Valtorta, Pietro Mortini, Carlo M. Croce, Lidia Larizza, Alfredo Fusco
Journal: Cancer Research
Cancer Res (2002) 62 (8): 2398–2405.
Published: 01 April 2002
View article titled, The <em>High Mobility Group A2</em> Gene Is Amplified and Overexpressed in Human Prolactinomas
Open the PDF for The <em>High Mobility Group A2</em> Gene Is Amplified and Overexpressed in Human Prolactinomas in another window