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Emanuele Loro
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Journal Articles

Abstract 6830: JZP815, a potent and selective pan-RAF inhibitor, is effective against a spectrum of mutant KRAS and NRAS solid tumor cancers, as monotherapy and in combination, generating a gene expression profile of MAPK inhibition

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Robert Hauptschein, Ankur Karmokar, Emanuele Loro, Yang Yuan, Graham Brock, Robin C. Humphreys, Alexey Sorokin, Preeti Kanikarla, Scott Kopetz
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 6830.
https://doi.org/10.1158/1538-7445.AM2025-6830
Published: 21 April 2025
View articletitled, Abstract 6830: JZP815, a potent and selective pan-RAF inhibitor, is effective against a spectrum of mutant KRAS and NRAS solid tumor cancers, as monotherapy and in combination, generating a gene expression profile of MAPK inhibition
Journal Articles

Cyclin D1 Restrains Oncogene-Induced Autophagy by Regulating the AMPK–LKB1 Signaling Axis

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Mathew C. Casimiro, Gabriele Di Sante, Agnese Di Rocco, Emanuele Loro, Claudia Pupo, Timothy G. Pestell, Sara Bisetto, Marco A. Velasco-Velázquez, Xuanmao Jiao, Zhiping Li, Christine M. Kusminski, Erin L. Seifert, Chenguang Wang, Daniel Ly, Bin Zheng, Che-Hung Shen, Philipp E. Scherer, Richard G. Pestell
Journal: Cancer Research
Cancer Res (2017) 77 (13): 3391–3405.
https://doi.org/10.1158/0008-5472.CAN-16-0425
Published: 02 July 2017
View articletitled, Cyclin D1 Restrains Oncogene-Induced Autophagy by Regulating the AMPK–LKB1 Signaling Axis
Open the PDF for Cyclin D1 Restrains Oncogene-Induced Autophagy by Regulating the AMPK–LKB1 Signaling Axis in another window
Includes: Supplementary data
Journal Articles

Abstract B10: Cyclin D1 restrains oncogene-induced autophagy via phosphorylation of LKB1

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Mathew Casimiro, Gabriele Di Sante, Emanuele Loro, Timothy Pestell, Sara Bisetto, Marco Velasco-Velázquez, Xuanmao Jiao, Zhiping Li, Chenguang Wang, Daniel Ly, Bin Zheng, Shen Che-Hung, Adam Ertel, Richard G. Pestell
Journal: Cancer Research
Cancer Res (2016) 76 (3_Supplement): B10.
https://doi.org/10.1158/1538-7445.FBCR15-B10
Published: 07 April 2016
View articletitled, Abstract B10: Cyclin D1 restrains oncogene-induced autophagy via phosphorylation of LKB1