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Emanuel F. Petricoin
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Journal Articles

Concurrent Inhibition of IGF1R and ERK Increases Pancreatic Cancer Sensitivity to Autophagy Inhibitors

Clint A. Stalnecker, Kajal R. Grover, A. Cole Edwards, Michael F. Coleman, Runying Yang, Jonathan M. DeLiberty, Björn Papke, Craig M. Goodwin, Mariaelena Pierobon, Emanuel F. Petricoin, III, Prson Gautam, Krister Wennerberg, Adrienne D. Cox, Channing J. Der, Stephen D. Hursting, Kirsten L. Bryant
Journal: Cancer Research
Cancer Res (2022) 82 (4): 586–598.
DOI: https://doi.org/10.1158/0008-5472.CAN-21-1443
Published: 17 December 2021
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Includes: Supplementary data
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Abstract 2000: Different oncogenic KRAS mutations produce distinct heterogenous outcomes in signaling pathways of isogenic mouse embryonic fibroblasts

Emna El Gazzah, Elisa Baldelli, Chamodya Ruhunsiri, Emanuel F. Petricoin, Mariaelena Pierobon
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2000.
DOI: https://doi.org/10.1158/1538-7445.AM2021-2000
Published: 01 July 2021
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Abstract 1993: Off-target effects of ultra-low dose dimethyl sulfoxide on targetable signaling events in lung cancer in vitro models

Elisa Baldelli, Mahalakshmi Subramanian, Abduljalil M. Alsubaie, Sara Baglivo, K A. Hodge, Fortunato Bianconi, Vienna Ludovini, Lucio Crino', Emanuel F. Petricoin, Mariaelena Pierobon
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1993.
DOI: https://doi.org/10.1158/1538-7445.AM2021-1993
Published: 01 July 2021
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Abstract 5451: Longitudinal proteomic assessment of patient with metastatic apocrine adenocarcinoma reveals evolutionary selection for androgen-receptor-dependence and therapeutic response

Erik Dvergsten, Anthony Serritella, Danielle Kimble, Malcom McIver, Sanja Karovic, Vasiliki Thomeas-McEwing, Hao Yang, Manish R. Sharma, Thomas P. Conrads, Mariaelena Pierobon, Peter Pytel, Binsheng Zhao, Lawrence H. Schwartz, Emanuel F. Petricoin, Russell Szmulewitz, Michael L. Maitland
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5451.
DOI: https://doi.org/10.1158/1538-7445.AM2020-5451
Published: 15 August 2020
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Abstract 5893: Comprehensive proteogenomic analysis and classification of lung adenocarcinoma

Anthony R. Soltis, Nicholas W. Bateman, Thomas P. Conrads, Clifton L. Dalgard, Hai Hu, Teri J. Franks, Jianfang Liu, Daoud Meerzaman, Emanuel F. Petricoin, Qingrong Chen, Chunhua Yan, Xijun Zhang, Clesson E. Turner, The APOLLO Research Network, Craig D. Shriver, Christopher A. Moskaluk, Robert F. Browning, Matthew D. Wilkerson
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5893.
DOI: https://doi.org/10.1158/1538-7445.AM2020-5893
Published: 15 August 2020
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Journal Articles

Abstract 4384: Quantitative assessment of drug combination effects in NSCLC cell lines through network-based analysis of functional protein activity

Chiara Antonini, George Rosenberger, Fortunato Bianconi, Lorenzo Tomassoni, Vienna Ludovini, Sara Baglivo, Sara Calandrini, Elisa Baldelli, Mariaelena Pierobon, Emanuel F. Petricoin, Andrea Califano
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4384.
DOI: https://doi.org/10.1158/1538-7445.AM2020-4384
Published: 15 August 2020
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Abstract 4091: Functional genomic screening in gemcitabine and cisplatin resistant bladder cancer cell lines identifies DNA repair pathways as mediators of chemosensitivity

Robert T. Jones, Tahlita C. Zuiverloon, Hedvig Vekony, Andrew Goodspeed, Teemu D. Laajala, Molishree Joshi, Colin Sempeck, Annie Jean, Megan Tu, Julia D. Wulfkuhle, Emanuel F. Petricoin, James C. Costello, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4091.
DOI: https://doi.org/10.1158/1538-7445.AM2020-4091
Published: 15 August 2020
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Abstract P4-10-31: Patterns of protein expression and signaling assessed by reverse phase protein array (RPPA) in estrogen-receptor negative (ER-), HER2-amplified breast cancer (BC) that was primary-refractory to preoperative (preop) HER2-directed therapy

Mariaelena Pierobon, Maren K Levin, Elisa Baldelli, Leslie SL Kim, Lance Liotta, Emanuel F Petricoin, Joyce O'Shaughnessy
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P4-10-31.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-P4-10-31
Published: 15 February 2020
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Journal Articles

Abstract PR10: Enhancing the effect of autophagy inhibition for pancreatic cancer treatment

Kirsten L. Bryant, Jennifer E. Klomp, Ye S. Lee, Clint A. Stalnecker, Kajal R. Grover, A. Cole Edwards, Sen Peng, Mariaelena Pierobon, Emanuel F. Petricoin, III, Nhan Tran, Alec C. Kimmelman, Adrienne D. Cox, Channing J. Der
Journal: Cancer Research
Cancer Res (2019) 79 (24_Supplement): PR10.
DOI: https://doi.org/10.1158/1538-7445.PANCA19-PR10
Published: 13 December 2019
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Abstract LB-287: Combination therapies with CDK4/6 inhibitors to treat KRAS-mutant pancreatic cancer

Craig M. Goodwin, Sehrish Javaid, Andrew M. Waters, Bjoern Papke, Runying Yang, Mariaelena Pierobon, Daniel M. Freed, Patrick J. Roberts, Adrienne D. Cox, Kris C. Wood, Emanuel F. Petricoin, Autumn J. McRee, Channing J. Der
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-287.
DOI: https://doi.org/10.1158/1538-7445.AM2019-LB-287
Published: 01 July 2019
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Journal Articles

Abstract 2145: Detect early tumor relapse in high-risk breast cancer

Amy H. Tang, Lauren L. Siewertsz van Reesema, Vasilena P. Zheleva, Janet S. Winston, Rick J. Jansen, Emanuel F. Petricoin, Matthew P. Goetz, Matthew P. Goetz, Harry D. Bear, Richard A. Hoefer
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2145.
DOI: https://doi.org/10.1158/1538-7445.AM2019-2145
Published: 01 July 2019
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Abstract LB-216: Protein pathway activation analysis of a panel of patient-derived epithelial tumor models identifies signatures of response to ErbB1-3 co-targeting

Valerie S. Calvert, Camilla Fröhlich, Thomas T. Poulsen, Mikkel W. Pedersen, Michael Kragh, Ivan D. Horak, Emanuel F. Petricoin
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-216.
DOI: https://doi.org/10.1158/1538-7445.AM2018-LB-216
Published: 01 July 2018
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Abstract 991: Development and characterization of patient derived xenografts from central nervous system metastasis reveal minor clone expansion linked with aggressive tumor behavior

Ben Yi Tew, Christophe Legendre, Tim Triche, Gerald C. Gooden, Kyle N. Johnson, Rae Anne Martinez, Emanuel F. Petricoin, Mariaelena Pierobon, Joyce O'Shaughnessy, Cindy Osborne, Mark A. Schroeder, Daniel J. Ma, Mark Bernstein, Jann N. Sarkaria, Steven A. Toms, Bodour Salhia
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 991.
DOI: https://doi.org/10.1158/1538-7445.AM2018-991
Published: 01 July 2018
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Abstract 2254: Dynamic network topologies analysis in proteomics data of NSCLC cell lines using a new pipeline based on machine learning tools

Chiara Antonini, Lorenzo Tomassoni, Elisa Baldelli, Vienna Ludovini, Sara Baglivo, Mariaelena Pierobon, Emanuel F Petricoin, Lucio Crinò, Paolo Valigi, Fortunato Bianconi
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2254.
DOI: https://doi.org/10.1158/1538-7445.AM2018-2254
Published: 01 July 2018
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Abstract 3129: PD-L1 expression differs across cancer metastatic sites from breast tumors

Mariaelena Pierobon, K Alex Hodge, Elisa Baldelli, Steven Anthony, Nicholas J. Robert, Donald W. Northfelt, Mohammad J. Jahanzeb, Linda Vocila, Lance A. Liotta, Bryant Dunetz, Emanuel F. Petricoin
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3129.
DOI: https://doi.org/10.1158/1538-7445.AM2018-3129
Published: 01 July 2018
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Abstract 3290: The Side-Out Foundation Metastatic Breast Cancer Database, an open-access portal for multi-omic molecular data and more

Elisa Baldelli, Shiva Ghaemi, Sanja Avramovic, Janusz Wojtusiak, Lance A. Liotta, Farrokh Alemi, Emanuel F. Petricoin, Bryant Dunetz, Mariaelena Pierobon
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3290.
DOI: https://doi.org/10.1158/1538-7445.AM2018-3290
Published: 01 July 2018
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Abstract 1829: PRAS40 as a mediator of insulin-like growth factor-1 receptor-induced resistance to epidermal growth factor receptor inhibition in head and neck cancer

Michael I. Dougherty, Christine E. Lehman, Rolando E. Mendez, Linnea E. Taniguchi, Julie Wulfkuhle, Emanuel F. Petricoin, Daniel G. Gioeli, Mark J. Jameson
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1829.
DOI: https://doi.org/10.1158/1538-7445.AM2018-1829
Published: 01 July 2018
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Targetable T-type Calcium Channels Drive Glioblastoma

Ying Zhang, Nichola Cruickshanks, Fang Yuan, Baomin Wang, Mary Pahuski, Julia Wulfkuhle, Isela Gallagher, Alexander F. Koeppel, Sarah Hatef, Christopher Papanicolas, Jeongwu Lee, Eli E. Bar, David Schiff, Stephen D. Turner, Emanuel F. Petricoin, Lloyd S. Gray, Roger Abounader
Journal: Cancer Research
Cancer Res (2017) 77 (13): 3479–3490.
DOI: https://doi.org/10.1158/0008-5472.CAN-16-2347
Published: 02 July 2017
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Abstract 2244: Pharmacological TLR4 antagonism using topical resatorvid blocks solar UV-induced skin tumorigenesis in SKH-1 mice

Sally E. Dickinson, Karen Blohm-Mangone, Nichole B. Burkett, Shekha Tahsin, Paul B. Myrdal, Kelly L. Karlage, Jaroslav Janda, Kathylynn Saboda, Denise J. Roe, Zigang Dong, Ann M. Bode, Emanuel F. Petricoin, Valerie S. Calvert, Clara Curiel-Lewandrowski, David S. Alberts, Georg T. Wondrak
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2244.
DOI: https://doi.org/10.1158/1538-7445.AM2017-2244
Published: 01 July 2017
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Abstract 4893: AKT1 signaling negatively regulates invasion and metastasis of non-small cell lung cancer cells carrying mutations in KRAS or EGFR

Guanhua Rao, Mariaelena Pierobon, In-Kyu Kim, Wei-Hsun Hsu, Jianghong Deng, Yong-Wha Moon, Emanuel F. Petricoin, Yu-Wen Zhang, Yisong Wang, Giuseppe Giaccone
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4893.
DOI: https://doi.org/10.1158/1538-7445.AM2017-4893
Published: 01 July 2017
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