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Abstract B18: The expression of CD74-regulated inflammatory markers in stage IV melanoma: Risk of CNS metastasis and patient survival

Dai Ogata, Sun-Hee Kim, Jason Roszik, Roland L Bassett, Jr, Elizabeth A Grimm, Suhendan Ekmekcioglu

Cancer Res (2020) 80 (19_Supplement): B18.

DOI: https://doi.org/10.1158/1538-7445.MEL2019-B18

Published: 02 October 2020

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Journal Articles

Abstract PR15: CD74 regulated inflammatory pattern is associated with TIL growth and favorable response to adoptive immunotherapy

Dai-Ogata, Caitlin A. Creasy, Sun-Hee Kim, Jason Roszik, Patrick Hwu, Elizabeth A. Grimm, Chantale Bernatchez, Suhendan Ekmekcioglu

Cancer Res (2020) 80 (19_Supplement): PR15.

DOI: https://doi.org/10.1158/1538-7445.MEL2019-PR15

Published: 02 October 2020

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Journal Articles

Abstract B10: High-dimensional (30-plex) imaging mass cytometry on tissue microarray identifies novel PD-L1-inclusive immunophenotypes associated with overall survival in stage III melanoma

Heather G. Hambright, Anand V.R. Kornepati, Dai Ogata, Roland R.L. Bassett, Suhendan Ekmekcioglu, Elizabeth A. Grimm, Tyler J. Curiel

Cancer Res (2020) 80 (19_Supplement): B10.

DOI: https://doi.org/10.1158/1538-7445.MEL2019-B10

Published: 02 October 2020

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Journal Articles

Abstract B13: Intrinsic microsomal PGE2 synthase-1 associates with poor patient survival and T-cell infiltration, and regulates immunosuppression in human and mouse melanoma models

Sun-Hee Kim, Jason Roszik, Sungnam Cho, Dai Ogata, Suhendan Ekmekcioglu, Elizabeth A Grimm

Cancer Res (2020) 80 (19_Supplement): B13.

DOI: https://doi.org/10.1158/1538-7445.MEL2019-B13

Published: 02 October 2020

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Journal Articles

Abstract IA08: Elevated endogenous SDHA drives pathologic metabolism in highly metastatic uveal melanoma

Chandrani Chattopadhyay, Junna Oba, Jason Roszik, Scott E. Woodman, Elizabeth A. Grimm

Cancer Res (2020) 80 (19_Supplement): IA08.

DOI: https://doi.org/10.1158/1538-7445.MEL2019-IA08

Published: 02 October 2020

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Journal Articles

Abstract B09: Nitric oxide stimulates PI3K-AKT pathway activation by S-nitrosylation of PTEN in human melanoma cells

Zhen Ding, Dai Ogata, Jason Roszik, Yong Qin, Sun-Hee Kim, Suhendan Ekmekcioglu, Elizabeth A. Grimm

Cancer Res (2020) 80 (19_Supplement): B09.

DOI: https://doi.org/10.1158/1538-7445.MEL2019-B09

Published: 02 October 2020

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Journal Articles

Abstract 3967: High microsomal PGE2synthase-1 levels associate with low CD8 T cells and poorer melanoma patient survival

Sun-Hee Kim, Jason Roszik, Weiyi Peng, Suhendan Ekmekcioglu, Elizabeth A. Grimm

Cancer Res (2017) 77 (13_Supplement): 3967.

DOI: https://doi.org/10.1158/1538-7445.AM2017-3967

Published: 01 July 2017

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Journal Articles

Abstract 2285: Microsomal PGE2 synthase-1 regulates melanoma cell survival and associates with melanoma disease progression

Sun-Hee Kim, Yuuri Hashimoto, Sung-Nam Cho, Jason Roszik, Denái R. Milton, Fulya Dal, Sangwon F. Kim, David G. Menter, Peiying Yang, Suhendan Ekmekcioglu, Elizabeth A. Grimm

Cancer Res (2016) 76 (14_Supplement): 2285.

DOI: https://doi.org/10.1158/1538-7445.AM2016-2285

Published: 15 July 2016

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Journal Articles

Abstract 3570: Differential expression of the melanoma inhibitor of apoptosis protein (ML-IAP)/Livin in patients with ulcerated and non-ulcerated melanomas

Nitin Chakravarti, Dawen Sui, Denái R. Milton, Wen-Jen Hwu, Elizabeth A. Grimm, Victor G. Prieto

Cancer Res (2016) 76 (14_Supplement): 3570.

DOI: https://doi.org/10.1158/1538-7445.AM2016-3570

Published: 15 July 2016

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Journal Articles

Abstract A32: A role for elevated leptin, independent of obesity, in the progression of melanoma

Junna Oba, Chandrani Chattopadhyay, Jeffrey E. Gershenwald, Marcella M. Johnson, Julie A. Ellerhorst, Elizabeth A. Grimm

Cancer Res (2015) 75 (14_Supplement): A32.

DOI: https://doi.org/10.1158/1538-7445.MEL2014-A32

Published: 16 July 2015

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Journal Articles

Abstract A27: Analyses of the level of liver borne growth factors, IGF-1 and HGF in metastatic and non-metastatic uveal melanoma patient serum: Correlation with outcome

Chandrani Chattopadhyay, Junna Oba, Bita Esmaeli, Julie A. Ellerhorst, Elizabeth A. Grimm

Cancer Res (2015) 75 (14_Supplement): A27.

DOI: https://doi.org/10.1158/1538-7445.MEL2014-A27

Published: 16 July 2015

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Journal Articles

Abstract 4200: Interaction between mPGES-1 and iNOS promotes human melanoma progression

Sun-Hee Kim, Yuuri Hashimoto, Suhendan Ekmekcioglu, Elizabeth A. Grimm

Cancer Res (2014) 74 (19_Supplement): 4200.

DOI: https://doi.org/10.1158/1538-7445.AM2014-4200

Published: 01 October 2014

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Journal Articles

Inducible Nitric Oxide Synthase Drives mTOR Pathway Activation and Proliferation of Human Melanoma by Reversible Nitrosylation of TSC2

Esther Lopez-Rivera, Padmini Jayaraman, Falguni Parikh, Michael A. Davies, Suhendan Ekmekcioglu, Sudeh Izadmehr, Denái R. Milton, Jerry E. Chipuk, Elizabeth A. Grimm, Yeriel Estrada, Julio Aguirre-Ghiso, Andrew G. Sikora

Cancer Res (2014) 74 (4): 1067–1078.

DOI: https://doi.org/10.1158/0008-5472.CAN-13-0588

Published: 16 February 2014

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Includes: Supplementary data

Journal Articles

Abstract 2936: Induction of hypoxia in 3D human melanoma spheroids leads to c-Met activation and resistance to Vemurafenib.

Yong Qin, Victoria R. Greene, Chandrani Chattopadhyay, Suhendan Ekmekcioglu, Chengwen Liu, Elizabeth A. Grimm

Cancer Res (2013) 73 (8_Supplement): 2936.

DOI: https://doi.org/10.1158/1538-7445.AM2013-2936

Published: 15 April 2013

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Journal Articles

Abstract 4988: The S-nitrosylation-mediated modification of p53 leads to altered DNA binding and associates with inactivity of p53 in human melanoma cells

Yong Qin, John Kwon, Li Li, Kevin P. Rosenblatt, Shuxing Zhang, Lu Chen, Gitanjali Jayachandran, Elizabeth A. Grimm

Cancer Res (2012) 72 (8_Supplement): 4988.

DOI: https://doi.org/10.1158/1538-7445.AM2012-4988

Published: 15 April 2012

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Journal Articles

Abstract 1833: A large-scale synthetic lethal RNAi screening identifies unique sensitizing targets for anti-inflammatory CDDO-Me in metastatic melanoma

Suhendan Ekmekcioglu, Yong Qin, Wuguo Deng, Elizabeth A. Grimm

Cancer Res (2012) 72 (8_Supplement): 1833.

DOI: https://doi.org/10.1158/1538-7445.AM2012-1833

Published: 15 April 2012

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Journal Articles

Abstract 5051: Aberrant endogenous expression of IL-1 promote inflammation and growth in human melanoma

Yong Qin, Suhendan Ekmekcioglu, Ping Liu, Nancy Poindexter, Elizabeth A. Grimm

Cancer Res (2011) 71 (8_Supplement): 5051.

DOI: https://doi.org/10.1158/1538-7445.AM2011-5051

Published: 15 April 2011

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Journal Articles

Abstract 5456: Preferential targeting of N-Ras mutant and other wild type B-Raf human melanoma cells with c-Met inhibitor: a preclinical promise

Chandrani Chattopadhyay, Julie A. Ellerhorst, Suhendan Ekmekcioglu, Elizabeth A. Grimm

Cancer Res (2010) 70 (8_Supplement): 5456.

DOI: https://doi.org/10.1158/1538-7445.AM10-5456

Published: 15 April 2010

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Journal Articles

Abstract 1175: PCR array-based gene expression profiling identifies CD70 and CD74 as molecular markers and potential therapeutic targets for human melanoma

Wuguo Deng, Suhendan Ekmekcioglu, Julie A. Ellerhorst, Nancy J. Poindexter, John Kwon, Sandra A. Kinney, Elizabeth A. Grimm

Cancer Res (2010) 70 (8_Supplement): 1175.

DOI: https://doi.org/10.1158/1538-7445.AM10-1175

Published: 15 April 2010

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Journal Articles

Abstract 4506: Elevated expression of IL-1 induces iNOS/NO production and inhibits IL-1Ra synthesis leading to progression of metastatic melanoma

Yong Qin, Suhendan Ekmekcioglu, Nancy Poindexter, Julie Ellerhorst, Elizabeth A. Grimm

Cancer Res (2010) 70 (8_Supplement): 4506.

DOI: https://doi.org/10.1158/1538-7445.AM10-4506

Published: 15 April 2010

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NARROW

Abstract B18: The expression of CD74-regulated inflammatory markers in stage IV melanoma: Risk of CNS metastasis and patient survival

Abstract PR15: CD74 regulated inflammatory pattern is associated with TIL growth and favorable response to adoptive immunotherapy

Abstract B10: High-dimensional (30-plex) imaging mass cytometry on tissue microarray identifies novel PD-L1-inclusive immunophenotypes associated with overall survival in stage III melanoma

Abstract B13: Intrinsic microsomal PGE2 synthase-1 associates with poor patient survival and T-cell infiltration, and regulates immunosuppression in human and mouse melanoma models

Abstract IA08: Elevated endogenous SDHA drives pathologic metabolism in highly metastatic uveal melanoma

Abstract B09: Nitric oxide stimulates PI3K-AKT pathway activation by S-nitrosylation of PTEN in human melanoma cells

Abstract 3967: High microsomal PGE2synthase-1 levels associate with low CD8 T cells and poorer melanoma patient survival

Abstract 2285: Microsomal PGE2 synthase-1 regulates melanoma cell survival and associates with melanoma disease progression

Abstract 3570: Differential expression of the melanoma inhibitor of apoptosis protein (ML-IAP)/Livin in patients with ulcerated and non-ulcerated melanomas

Abstract A32: A role for elevated leptin, independent of obesity, in the progression of melanoma

Abstract A27: Analyses of the level of liver borne growth factors, IGF-1 and HGF in metastatic and non-metastatic uveal melanoma patient serum: Correlation with outcome

Abstract 4200: Interaction between mPGES-1 and iNOS promotes human melanoma progression

Inducible Nitric Oxide Synthase Drives mTOR Pathway Activation and Proliferation of Human Melanoma by Reversible Nitrosylation of TSC2

Abstract 2936: Induction of hypoxia in 3D human melanoma spheroids leads to c-Met activation and resistance to Vemurafenib.

Abstract 4988: The S-nitrosylation-mediated modification of p53 leads to altered DNA binding and associates with inactivity of p53 in human melanoma cells

Abstract 1833: A large-scale synthetic lethal RNAi screening identifies unique sensitizing targets for anti-inflammatory CDDO-Me in metastatic melanoma

Abstract 5051: Aberrant endogenous expression of IL-1 promote inflammation and growth in human melanoma

Abstract 5456: Preferential targeting of N-Ras mutant and other wild type B-Raf human melanoma cells with c-Met inhibitor: a preclinical promise

Abstract 1175: PCR array-based gene expression profiling identifies CD70 and CD74 as molecular markers and potential therapeutic targets for human melanoma

Abstract 4506: Elevated expression of IL-1 induces iNOS/NO production and inhibits IL-1Ra synthesis leading to progression of metastatic melanoma

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