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Elena N. Pugacheva
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Journal Articles

Abstract 1296: Targeting nuclear AURKA and hypoxia signaling pathway attenuates metastatic burden in triple negative breast cancer

Abha Maskey, Kristina Marinak Whately, Elena N. Pugacheva
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1296.
https://doi.org/10.1158/1538-7445.AM2023-1296
Published: 04 April 2023
View article titled, Abstract 1296: Targeting nuclear AURKA and hypoxia signaling pathway attenuates metastatic burden in triple negative breast cancer
Journal Articles

Abstract 1084: Combination of eribulin and AURKA inhibitor prevents metastatic colonization and eradicates established metastases in breast cancer

Elena N. Pugacheva, Varvara Kozyreva, Anna Kiseleva, Ryan Ice, Brandon Jones, Yuriy Loskutov
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1084.
https://doi.org/10.1158/1538-7445.AM2017-1084
Published: 01 July 2017
View article titled, Abstract 1084: Combination of eribulin and AURKA inhibitor prevents metastatic colonization and eradicates established metastases in breast cancer
Journal Articles

KAP1 Promotes Proliferation and Metastatic Progression of Breast Cancer Cells

Joseph B. Addison, Colton Koontz, James H. Fugett, Chad J. Creighton, Dongquan Chen, Mark K. Farrugia, Renata R. Padon, Maria A. Voronkova, Sarah L. McLaughlin, Ryan H. Livengood, Chen-Chung Lin, J. Michael Ruppert, Elena N. Pugacheva, Alexey V. Ivanov
Journal: Cancer Research
Cancer Res (2015) 75 (2): 344–355.
https://doi.org/10.1158/0008-5472.CAN-14-1561
Published: 14 January 2015
View article titled, KAP1 Promotes Proliferation and Metastatic Progression of Breast Cancer Cells
Open the PDF for KAP1 Promotes Proliferation and Metastatic Progression of Breast Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Abstract B61: HEF1-dependent Aurora A kinase phosphorylation activates HDAC6

Varvara K. Kozyreva, Sarah L. McLaughlin, Laura Kelley, Elena N. Pugacheva
Journal: Cancer Research
Cancer Res (2011) 71 (18_Supplement): B61.
https://doi.org/10.1158/1538-7445.FBCR11-B61
Published: 28 October 2014
View article titled, Abstract B61: HEF1-dependent Aurora A kinase phosphorylation activates HDAC6
Journal Articles

Abstract 2013: NEDD9 depletion leads to MMP14 inactivation by TIMP2 and prevents invasion and metastasis

Elena N. Pugacheva, Sarah McLaughlin, Ryan Ice, Anuradha Rajulapati, Polina Kozyulina, Ryan Livengood, Varvara Kozyreva, Yuriy Loskutov, Alexey Ivanov, Scott Weed
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2013.
https://doi.org/10.1158/1538-7445.AM2014-2013
Published: 01 October 2014
View article titled, Abstract 2013: NEDD9 depletion leads to MMP14 inactivation by TIMP2 and prevents invasion and metastasis
Journal Articles

Abstract A66: NEDD9 promotes cell invasion through modulation of ARF6 activity and endocytic recycling

Elena N. Pugacheva, Yuriy Loskutov, Sarah McLaughlin, Polina Kozyulina, Varvara Kozyreva, Ryan Ice, Mark Culp, Robert Wysolmerski, Scott Weed, Alexey Ivanov
Journal: Cancer Research
Cancer Res (2013) 73 (3_Supplement): A66.
https://doi.org/10.1158/1538-7445.TIM2013-A66
Published: 01 May 2014
View article titled, Abstract A66: NEDD9 promotes cell invasion through modulation of ARF6 activity and endocytic recycling
Journal Articles

NEDD9 Depletion Destabilizes Aurora A Kinase and Heightens the Efficacy of Aurora A Inhibitors: Implications for Treatment of Metastatic Solid Tumors

Ryan J. Ice, Sarah L. McLaughlin, Ryan H. Livengood, Mark V. Culp, Erik R. Eddy, Alexey V. Ivanov, Elena N. Pugacheva
Journal: Cancer Research
Cancer Res (2013) 73 (10): 3168–3180.
https://doi.org/10.1158/0008-5472.CAN-12-4008
Published: 12 May 2013
View article titled, NEDD9 Depletion Destabilizes Aurora A Kinase and Heightens the Efficacy of Aurora A Inhibitors: Implications for Treatment of Metastatic Solid Tumors
Open the PDF for NEDD9 Depletion Destabilizes Aurora A Kinase and Heightens the Efficacy of Aurora A Inhibitors: Implications for Treatment of Metastatic Solid Tumors in another window
Includes: Supplementary data
Journal Articles

Abstract 3125: KAP1 promotes malignant properties of breast cancer cells and regulates the expression of multiple KRAB-ZNFs.

Joseph B. Addison, Renata Galeeva, Dongquan Chen, Elena N. Pugacheva, Alexey V. Ivanov
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3125.
https://doi.org/10.1158/1538-7445.AM2013-3125
Published: 15 April 2013
View article titled, Abstract 3125: KAP1 promotes malignant properties of breast cancer cells and regulates the expression of multiple KRAB-ZNFs.
Journal Articles

Abstract 4934: The role of Aurora A kinase-dependent phosphorylation of cortactin in invadopodia formation.

Varvara K. Kozyreva, Laura Kelley, Sarah L. McLaughlin, Elena N. Pugacheva
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4934.
https://doi.org/10.1158/1538-7445.AM2013-4934
Published: 15 April 2013
View article titled, Abstract 4934: The role of Aurora A kinase-dependent phosphorylation of cortactin in invadopodia formation.
Journal Articles

Abstract 1086: The role of HEF1 protein in stabilization and activation of AurA kinase in metastatic breast cancer

Elena N. Pugacheva, Sarah McLaughlin, Bridget Hindman, Erica A. Golemis
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1086.
https://doi.org/10.1158/1538-7445.AM10-1086
Published: 15 April 2010
View article titled, Abstract 1086: The role of HEF1 protein in stabilization and activation of AurA kinase in metastatic breast cancer
Journal Articles

NEDD9 Promotes Oncogenic Signaling in Mammary Tumor Development

Eugene Izumchenko, Mahendra K. Singh, Olga V. Plotnikova, Nadezhda Tikhmyanova, Joy L. Little, Ilya G. Serebriiskii, Sachiko Seo, Mineo Kurokawa, Brian L. Egleston, Andres Klein-Szanto, Elena N. Pugacheva, Richard R. Hardy, Marina Wolfson, Denise C. Connolly, Erica A. Golemis
Journal: Cancer Research
Cancer Res (2009) 69 (18): 7198–7206.
https://doi.org/10.1158/0008-5472.CAN-09-0795
Published: 14 September 2009
View article titled, NEDD9 Promotes Oncogenic Signaling in Mammary Tumor Development
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Includes: Supplementary data
Journal Articles

Cell Cycle–Dependent Ciliogenesis and Cancer

Olga V. Plotnikova, Erica A. Golemis, Elena N. Pugacheva
Journal: Cancer Research
Cancer Res (2008) 68 (7): 2058–2061.
https://doi.org/10.1158/0008-5472.CAN-07-5838
Published: 01 April 2008
View article titled, Cell Cycle–Dependent Ciliogenesis and Cancer
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