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Journal Articles

Abstract 1847: Cooperativity between glutaminase 1 and histone deacetylase SIRT7 regulates TGF-β mediated lung fibrosis

Malay Choudhury, Xueqian Yin, Jeong-Han Kang, Mahefatiana Andrianifahanana, Edward B. Leof

Cancer Res (2019) 79 (13_Supplement): 1847.

https://doi.org/10.1158/1538-7445.AM2019-1847

Published: 01 July 2019

View article titled, Abstract 1847: Cooperativity between glutaminase 1 and histone deacetylase SIRT7 regulates TGF-β mediated lung fibrosis

Journal Articles

Abstract LB-028: Cell density sensing alters TGF-beta signaling in a cell type-specific manner, independent from Hippo pathway activation

Flore Nallet-Staub, Xueqian Yin, Cristèle Gilbert, Véronique Marsaud, Saber Ben Mimoun, Delphine Javelaud, Edward B. Leof, Alain Mauviel

Cancer Res (2015) 75 (15_Supplement): LB-028.

https://doi.org/10.1158/1538-7445.AM2015-LB-028

Published: 01 August 2015

View article titled, Abstract LB-028: Cell density sensing alters TGF-beta signaling in a cell type-specific manner, independent from Hippo pathway activation

Journal Articles

Abstract 3462: Comparative RNA-Seq analysis of MIS signaling: Potential relevance as therapeutic strategy in ovarian cancer treatment

Qing Zhang, Eati Basal, Jaime I. Davila, Xueqian Yin, Edward B. Leof, William A. Cliby

Cancer Res (2014) 74 (19_Supplement): 3462.

https://doi.org/10.1158/1538-7445.AM2014-3462

Published: 01 October 2014

View article titled, Abstract 3462: Comparative RNA-Seq analysis of MIS signaling: Potential relevance as therapeutic strategy in ovarian cancer treatment

Journal Articles

Abstract B40: SIAH-dependent SMAD2/3/4 ubiquitination and degradation in mediating the K-RAS-TGFβ antagonism during tumorigenesis and metastasis in human pancreatic cancer cells.

Amy H. Tang, Yang Liao, Maryanne Edens, Ralf Janknecht, Edward B. Leof

Cancer Res (2012) 72 (14_Supplement): B40.

https://doi.org/10.1158/1538-7445.PANCA2012-B40

Published: 03 April 2014

View article titled, Abstract B40: SIAH-dependent SMAD2/3/4 ubiquitination and degradation in mediating the K-RAS-TGFβ antagonism during tumorigenesis and metastasis in human pancreatic cancer cells.

Journal Articles

Abstract 1980: The SIAH2-SMAD2/3/4 antagonism downstream of the K-RAS and TGFβ signaling pathways during tumor initiation, progression and metastasis of human cancer

Yang Liao, Maryanne Edens, Ralf G. Janknecht, Edward B. Leof, Amy H. Tang

Cancer Res (2011) 71 (8_Supplement): 1980.

https://doi.org/10.1158/1538-7445.AM2011-1980

Published: 15 April 2011

View article titled, Abstract 1980: The SIAH2-SMAD2/3/4 antagonism downstream of the K-RAS and TGFβ signaling pathways during tumor initiation, progression and metastasis of human cancer

Journal Articles

ERBB Receptor Activation Is Required for Profibrotic Responses to Transforming Growth Factor β

Mahefatiana Andrianifahanana, Mark C. Wilkes, Claire E. Repellin, Maryanne Edens, Theodore J. Kottom, Rod A. Rahimi, Edward B. Leof

Cancer Res (2010) 70 (19): 7421–7430.

https://doi.org/10.1158/0008-5472.CAN-10-0232

Published: 29 September 2010

View article titled, ERBB Receptor Activation Is Required for Profibrotic Responses to Transforming Growth Factor β

Includes: Supplementary data

Journal Articles

Abstract 5073: SIAH2 antagonizes the growth-inhibitory activity of the TGFβ signaling pathway and enhances the growth-promoting activity of the RAS signaling pathway during the genesis and progression of human cancer

Yang Liao, Maryanne Edens, Edward B. Leof, Amy H. Tang

Cancer Res (2010) 70 (8_Supplement): 5073.

https://doi.org/10.1158/1538-7445.AM10-5073

Published: 15 April 2010

View article titled, Abstract 5073: SIAH2 antagonizes the growth-inhibitory activity of the TGFβ signaling pathway and enhances the growth-promoting activity of the RAS signaling pathway during the genesis and progression of human cancer

Journal Articles

Distinct Roles for Mammalian Target of Rapamycin Complexes in the Fibroblast Response to Transforming Growth Factor-β

Rod A. Rahimi, Mahefatiana Andrianifahanana, Mark C. Wilkes, Maryanne Edens, Theodore J. Kottom, John Blenis, Edward B. Leof

Cancer Res (2009) 69 (1): 84–93.

https://doi.org/10.1158/0008-5472.CAN-08-2146

Published: 31 December 2008

View article titled, Distinct Roles for Mammalian Target of Rapamycin Complexes in the Fibroblast Response to Transforming Growth Factor-β

Journal Articles

Transforming Growth Factor β Signaling via Ras in Mesenchymal Cells Requires p21-Activated Kinase 2 for Extracellular Signal-Regulated Kinase-Dependent Transcriptional Responses

Kaori Suzuki, Mark C. Wilkes, Nandor Garamszegi, Maryanne Edens, Edward B. Leof

Cancer Res (2007) 67 (8): 3673–3682.

https://doi.org/10.1158/0008-5472.CAN-06-3211

Published: 17 April 2007

View article titled, Transforming Growth Factor β Signaling via Ras in Mesenchymal Cells Requires p21-Activated Kinase 2 for Extracellular Signal-Regulated Kinase-Dependent Transcriptional Responses

Journal Articles

Transforming Growth Factor-β Activation of Phosphatidylinositol 3-Kinase Is Independent of Smad2 and Smad3 and Regulates Fibroblast Responses via p21-Activated Kinase-2

Mark C. Wilkes, Hugh Mitchell, Sumedha Gulati Penheiter, Jules J. Doré, Kaori Suzuki, Maryanne Edens, Deepak K. Sharma, Richard E. Pagano, Edward B. Leof

Cancer Res (2005) 65 (22): 10431–10440.

https://doi.org/10.1158/0008-5472.CAN-05-1522

Published: 15 November 2005

View article titled, Transforming Growth Factor-β Activation of Phosphatidylinositol 3-Kinase Is Independent of Smad2 and Smad3 and Regulates Fibroblast Responses via p21-Activated Kinase-2

Journal Articles

Dissociation of p34^cdc2 Complex Formation from Phosphorylation and Histone H1 Kinase Activity

Scott T. Eblen, Michael P. Fautsch, Rebekah J. Burnette, Melissa Snyder, Edward B. Leof

Cancer Res (1995) 55 (9): 1994–2000.

Published: 01 May 1995

View article titled, Dissociation of p34cdc2 Complex Formation from Phosphorylation and Histone H1 Kinase Activity

Journal Articles

Regulation of Transforming Growth Factor β1 Action by Multiple Transducing Pathways: Evidence for Both G Protein-dependent and -independent Signaling

Philip H. Howe, Charles C. Bascom, Muriel R. Cunningham, Edward B. Leof

Cancer Res (1989) 49 (21): 6024–6031.

Published: 01 November 1989

View article titled, Regulation of Transforming Growth Factor β1 Action by Multiple Transducing Pathways: Evidence for Both G Protein-dependent and -independent Signaling

Journal Articles

Mid-G₁ Arrest and Epidermal Growth Factor Independence of ras-transfected Mouse Cells

Edward B. Leof, Russette M. Lyons, Muriel R. Cunningham, Deirdre O'Sullivan

Cancer Res (1989) 49 (9): 2356–2361.

Published: 01 May 1989

View article titled, Mid-G1 Arrest and Epidermal Growth Factor Independence of ras-transfected Mouse Cells

Journal Articles

Growth Factors and Cancer

Anton Scott Goustin, Edward B. Leof, Gary D. Shipley, Harold L. Moses

Cancer Res (1986) 46 (3): 1015–1029.

Published: 01 March 1986

View article titled, Growth Factors and Cancer

NARROW

Abstract 1847: Cooperativity between glutaminase 1 and histone deacetylase SIRT7 regulates TGF-β mediated lung fibrosis

Abstract LB-028: Cell density sensing alters TGF-beta signaling in a cell type-specific manner, independent from Hippo pathway activation

Abstract 3462: Comparative RNA-Seq analysis of MIS signaling: Potential relevance as therapeutic strategy in ovarian cancer treatment

Abstract B40: SIAH-dependent SMAD2/3/4 ubiquitination and degradation in mediating the K-RAS-TGFβ antagonism during tumorigenesis and metastasis in human pancreatic cancer cells.

Abstract 1980: The SIAH2-SMAD2/3/4 antagonism downstream of the K-RAS and TGFβ signaling pathways during tumor initiation, progression and metastasis of human cancer

ERBB Receptor Activation Is Required for Profibrotic Responses to Transforming Growth Factor β

Abstract 5073: SIAH2 antagonizes the growth-inhibitory activity of the TGFβ signaling pathway and enhances the growth-promoting activity of the RAS signaling pathway during the genesis and progression of human cancer

Distinct Roles for Mammalian Target of Rapamycin Complexes in the Fibroblast Response to Transforming Growth Factor-β

Transforming Growth Factor β Signaling via Ras in Mesenchymal Cells Requires p21-Activated Kinase 2 for Extracellular Signal-Regulated Kinase-Dependent Transcriptional Responses

Transforming Growth Factor-β Activation of Phosphatidylinositol 3-Kinase Is Independent of Smad2 and Smad3 and Regulates Fibroblast Responses via p21-Activated Kinase-2

Dissociation of p34^cdc2 Complex Formation from Phosphorylation and Histone H1 Kinase Activity

Regulation of Transforming Growth Factor β1 Action by Multiple Transducing Pathways: Evidence for Both G Protein-dependent and -independent Signaling

Mid-G₁ Arrest and Epidermal Growth Factor Independence of ras-transfected Mouse Cells

Growth Factors and Cancer

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