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Journal Articles

Abstract 3626: Day 21 early bone marrow response does not offer high concordance with response bone marrow in the induction chemotherapy setting of FLT3 mutant acute myeloid leukemia

Vincent Lok, Su Bin Hahn, Nikesh N. Shah, Daniel A. Kerr, Ivan M. Borrello, Eduardo M. Sotomayor, David M. Swoboda

Cancer Res (2024) 84 (6_Supplement): 3626.

https://doi.org/10.1158/1538-7445.AM2024-3626

Published: 22 March 2024

View article titled, Abstract 3626: Day 21 early bone marrow response does not offer high concordance with response bone marrow in the induction chemotherapy setting of <em>FLT3</em> mutant acute myeloid leukemia

Journal Articles

HDAC6 Plays a Noncanonical Role in the Regulation of Antitumor Immune Responses, Dissemination, and Invasiveness of Breast Cancer

Debarati Banik, Satish Noonepalle, Melissa Hadley, Erica Palmer, Maria Gracia-Hernandez, Christian Zevallos-Delgado, Namratta Manhas, Hayk Simonyan, Colin N. Young, Anastas Popratiloff, Katherine B. Chiappinelli, Rohan Fernandes, Eduardo M. Sotomayor, Alejandro Villagra

Cancer Res (2020) 80 (17): 3649–3662.

https://doi.org/10.1158/0008-5472.CAN-19-3738

Published: 02 September 2020

View article titled, HDAC6 Plays a Noncanonical Role in the Regulation of Antitumor Immune Responses, Dissemination, and Invasiveness of Breast Cancer

Includes: Multimedia, Supplementary data

Journal Articles

Abstract 4967: HDAC11 function as a transcriptional regulator in immature myeloid cells to myeloid-derived suppressor cells transition

Jie Chen, Fengdong Cheng, Eva Sahakian, John Powers, Zi Wang, Alejandro Villagra, Javier Pinilla-Ibarz, Eduardo M. Sotomayor

Cancer Res (2018) 78 (13_Supplement): 4967.

https://doi.org/10.1158/1538-7445.AM2018-4967

Published: 01 July 2018

View article titled, Abstract 4967: HDAC11 function as a transcriptional regulator in immature myeloid cells to myeloid-derived suppressor cells transition

Journal Articles

Abstract 1338: Novel implications of histone deacetylase 6 selective inhibition in melanoma T-cell immunotherapy

Andressa Sodre Laino, David M. Woods, Amod Sarnaik, Esteban Celis, Jeffrey Weber, Eduardo M. Sotomayor

Cancer Res (2015) 75 (15_Supplement): 1338.

https://doi.org/10.1158/1538-7445.AM2015-1338

Published: 01 August 2015

View article titled, Abstract 1338: Novel implications of histone deacetylase 6 selective inhibition in melanoma T-cell immunotherapy

Journal Articles

Abstract 257: Class I HDAC inhibition upregulates PD-1 ligands in melanoma and increases the efficacy of PD-1 blockade

David M. Woods, Andressa L. Sodre, Amod Sarnaik, Eduardo M. Sotomayor, Jeffrey Weber

Cancer Res (2015) 75 (15_Supplement): 257.

https://doi.org/10.1158/1538-7445.AM2015-257

Published: 01 August 2015

View article titled, Abstract 257: Class I HDAC inhibition upregulates PD-1 ligands in melanoma and increases the efficacy of PD-1 blockade

Journal Articles

Abstract 2564: Histone deacetylase 6 is a novel target for enhancing T-cell function during anti-tumor response and tumor-peptide vaccination

Andressa S. Laino, David M. Woods, Fengdong Cheng, HongWei Wang, Eduardo M. Sotomayor

Cancer Res (2014) 74 (19_Supplement): 2564.

https://doi.org/10.1158/1538-7445.AM2014-2564

Published: 01 October 2014

View article titled, Abstract 2564: Histone deacetylase 6 is a novel target for enhancing T-cell function during anti-tumor response and tumor-peptide vaccination

Journal Articles

Abstract 643: The histone deacetylase inhibitor Quisinostat augments the anti-tumor reponses of T-cells: Implications in adoptive cell therapy

David M. Woods, Andressa L. Sodre, Jason B. Brayer, Eduardo M. Sotomayor

Cancer Res (2014) 74 (19_Supplement): 643.

https://doi.org/10.1158/1538-7445.AM2014-643

Published: 01 October 2014

View article titled, Abstract 643: The histone deacetylase inhibitor Quisinostat augments the anti-tumor reponses of T-cells: Implications in adoptive cell therapy

Journal Articles

Abstract 4086: Histone deacetylase 6 (HDAC6) as a new target modulating the proliferation and immune-related pathways in melanoma

Patricio Perez-Villarroel, Maritza Lienlaf, Calvin Lee, Fengdong Cheng, David Woods, Kelly Barrios, Karrune Woan, Jorge Canales, Tessa Knox, Danay Marante, Hongwei Wang, Pedro Horna, Keiran Smalley, Esteban Celis, Ed Seto, Jeffrey S. Weber, Eduardo M. Sotomayor, Alejandro Villagra

Cancer Res (2014) 74 (19_Supplement): 4086.

https://doi.org/10.1158/1538-7445.AM2014-4086

Published: 01 October 2014

View article titled, Abstract 4086: Histone deacetylase 6 (HDAC6) as a new target modulating the proliferation and immune-related pathways in melanoma

Journal Articles

Abstract 4089: Histone deacetylase 6 (HDAC6) as a regulator of PD-L1 expression through STAT3 modulation in melanoma

Maritza Lienlaf, Patricio Perez-Villarroel, Calvin Lee, Fengdong Cheng, Jorge Canales, Tessa Knox, Danay Marante, Amod Sarnaik, Pedro Horna, Ed. Seto, Keiran Smalley, Jeffrey S. Weber, Eduardo M. Sotomayor, Alejandro Villagra

Cancer Res (2014) 74 (19_Supplement): 4089.

https://doi.org/10.1158/1538-7445.AM2014-4089

Published: 01 October 2014

View article titled, Abstract 4089: Histone deacetylase 6 (HDAC6) as a regulator of PD-L1 expression through STAT3 modulation in melanoma

Journal Articles

Abstract 4944: Combined treatment of BTK and PI3K inhibitors synergistically disrupts BCR-signaling, overcomes microenviroment-mediated survival and drug resistance in mantle cell lymphoma.

Jiangchuan Tao, Tint Lwin, Xiaohong Zhao, Bijal Shah, Ling Zhang, Lynn Moscinski, William Dalton, Eduardo M. Sotomayor, Jianguo Tao

Cancer Res (2013) 73 (8_Supplement): 4944.

https://doi.org/10.1158/1538-7445.AM2013-4944

Published: 15 April 2013

View article titled, Abstract 4944: Combined treatment of BTK and PI3K inhibitors synergistically disrupts BCR-signaling, overcomes microenviroment-mediated survival and drug resistance in mantle cell lymphoma.

Journal Articles

Abstract 5246: Histone deacetylase 6 (HDAC6) as a new modulator of the JAK/STAT pathway in melanoma.

Maritza Lienlaf, Patricio Perez-Villarroel, Jorge Canales, Tessa Knox, Fengdong Cheng, Danay Marante, David Woods, Karrune Woan, HongWei Wang, Ed Seto, Jeffrey S. Weber, Eduardo M. Sotomayor, Alejandro Villagra

Cancer Res (2013) 73 (8_Supplement): 5246.

https://doi.org/10.1158/1538-7445.AM2013-5246

Published: 15 April 2013

View article titled, Abstract 5246: Histone deacetylase 6 (HDAC6) as a new modulator of the JAK/STAT pathway in melanoma.

Journal Articles

Stat3 Inhibition Augments the Immunogenicity of B-cell Lymphoma Cells, Leading to Effective Antitumor Immunity

Fengdong Cheng, Hongwei Wang, Pedro Horna, Zi Wang, Bijal Shah, Eva Sahakian, Karrune V. Woan, Alejandro Villagra, Javier Pinilla-Ibarz, Said Sebti, Mitchell Smith, Jianguo Tao, Eduardo M. Sotomayor

Cancer Res (2012) 72 (17): 4440–4448.

https://doi.org/10.1158/0008-5472.CAN-11-3619

Published: 30 August 2012

View article titled, Stat3 Inhibition Augments the Immunogenicity of B-cell Lymphoma Cells, Leading to Effective Antitumor Immunity

Includes: Supplementary data

Journal Articles

Abstract 3555: Histone deacetylase 6 as a novel regulator of the immunogenicity and aggressiveness of melanoma

Cancer Res (2012) 72 (8_Supplement): 3555.

https://doi.org/10.1158/1538-7445.AM2012-3555

Published: 15 April 2012

View article titled, Abstract 3555: Histone deacetylase 6 as a novel regulator of the immunogenicity and aggressiveness of melanoma

Journal Articles

Abstract 3554: The histone deacetylase inhibitor LBH589 augments anti-tumor immunity through direct effects on tumor and immune cells leading to impaired tumor progression in vivo

David M. Woods, Karrune V. Woan, Hongwei Wang, Fengdong Cheng, Zi Wang, Lianet Vazquez, Patricio Perez, Maritza Lienlaf, Jennifer Rock-Klotz, Eva Sahakian, John Powers, Susan Deng, Merino Oscar, Peter Atadja, Ed Seto, Javier Pinilla-Ibarz, Jeffrey S. Weber, Eduardo M. Sotomayor, Alejandro Villagra

Cancer Res (2012) 72 (8_Supplement): 3554.

https://doi.org/10.1158/1538-7445.AM2012-3554

Published: 15 April 2012

View article titled, Abstract 3554: The histone deacetylase inhibitor LBH589 augments anti-tumor immunity through direct effects on tumor and immune cells leading to impaired tumor progression <em>in vivo</em>

Journal Articles

Abstract 5526: Epigenetic repolarization of T lymphocytes from chronic lymphocytic leukemia patients using 5-aza-2’-deoxycytidine

Jason A. Dubovsky, John J. Powers, Yang Gao, Luis F. Mariusso, Eduardo M. Sotomayor, Javier A. Pinilla-Ibarz

Cancer Res (2011) 71 (8_Supplement): 5526.

https://doi.org/10.1158/1538-7445.AM2011-5526

Published: 15 April 2011

View article titled, Abstract 5526: Epigenetic repolarization of T lymphocytes from chronic lymphocytic leukemia patients using 5-aza-2’-deoxycytidine

Journal Articles

Abstract 4771: Molecular, epigenetic, and phenotypic repolarization of human T lymphocytes using 5-aza-2′-deoxycytidine increases CD8 responsiveness and induces Th1 polarity

Jason A. Dubovsky, John J. Powers, Yang Gao, Javier A. Pinilla-Ibarz, Eduardo M. Sotomayor

Cancer Res (2010) 70 (8_Supplement): 4771.

https://doi.org/10.1158/1538-7445.AM10-4771

Published: 15 April 2010

View article titled, Abstract 4771: Molecular, epigenetic, and phenotypic repolarization of human T lymphocytes using 5-aza-2′-deoxycytidine increases CD8 responsiveness and induces Th1 polarity

Journal Articles

Arginase I Production in the Tumor Microenvironment by Mature Myeloid Cells Inhibits T-Cell Receptor Expression and Antigen-Specific T-Cell Responses

Paulo C. Rodriguez, David G. Quiceno, Jovanny Zabaleta, Blair Ortiz, Arnold H. Zea, Maria B. Piazuelo, Alberto Delgado, Pelayo Correa, Jason Brayer, Eduardo M. Sotomayor, Scott Antonia, Juan B. Ochoa, Augusto C. Ochoa

Cancer Res (2004) 64 (16): 5839–5849.

https://doi.org/10.1158/0008-5472.CAN-04-0465

Published: 16 August 2004

View article titled, Arginase I Production in the Tumor Microenvironment by Mature Myeloid Cells Inhibits T-Cell Receptor Expression and Antigen-Specific T-Cell Responses

Journal Articles

Extra-Lymphatic Solid Tumor Growth Is Not Immunologically Ignored and Results in Early Induction of Antigen-Specific T-Cell Anergy: Dominant Role of Cross-Tolerance to Tumor Antigens

Alex Cuenca, Fengdong Cheng, Hongwei Wang, Jason Brayer, Pedro Horna, Lingping Gu, Harold Bien, Ivan M. Borrello, Hyam I. Levitsky, Eduardo M. Sotomayor

Cancer Res (2003) 63 (24): 9007–9015.

Published: 24 December 2003

View article titled, Extra-Lymphatic Solid Tumor Growth Is Not Immunologically Ignored and Results in Early Induction of Antigen-Specific T-Cell Anergy: <subtitle>Dominant Role of Cross-Tolerance to Tumor Antigens</subtitle>

NARROW

Abstract 3626: Day 21 early bone marrow response does not offer high concordance with response bone marrow in the induction chemotherapy setting of FLT3 mutant acute myeloid leukemia

HDAC6 Plays a Noncanonical Role in the Regulation of Antitumor Immune Responses, Dissemination, and Invasiveness of Breast Cancer

Abstract 4967: HDAC11 function as a transcriptional regulator in immature myeloid cells to myeloid-derived suppressor cells transition

Abstract 1338: Novel implications of histone deacetylase 6 selective inhibition in melanoma T-cell immunotherapy

Abstract 257: Class I HDAC inhibition upregulates PD-1 ligands in melanoma and increases the efficacy of PD-1 blockade

Abstract 2564: Histone deacetylase 6 is a novel target for enhancing T-cell function during anti-tumor response and tumor-peptide vaccination

Abstract 643: The histone deacetylase inhibitor Quisinostat augments the anti-tumor reponses of T-cells: Implications in adoptive cell therapy

Abstract 4086: Histone deacetylase 6 (HDAC6) as a new target modulating the proliferation and immune-related pathways in melanoma

Abstract 4089: Histone deacetylase 6 (HDAC6) as a regulator of PD-L1 expression through STAT3 modulation in melanoma

Abstract 4944: Combined treatment of BTK and PI3K inhibitors synergistically disrupts BCR-signaling, overcomes microenviroment-mediated survival and drug resistance in mantle cell lymphoma.

Abstract 5246: Histone deacetylase 6 (HDAC6) as a new modulator of the JAK/STAT pathway in melanoma.

Stat3 Inhibition Augments the Immunogenicity of B-cell Lymphoma Cells, Leading to Effective Antitumor Immunity

Abstract 3555: Histone deacetylase 6 as a novel regulator of the immunogenicity and aggressiveness of melanoma

Abstract 3554: The histone deacetylase inhibitor LBH589 augments anti-tumor immunity through direct effects on tumor and immune cells leading to impaired tumor progression in vivo

Abstract 5526: Epigenetic repolarization of T lymphocytes from chronic lymphocytic leukemia patients using 5-aza-2’-deoxycytidine

Abstract 4771: Molecular, epigenetic, and phenotypic repolarization of human T lymphocytes using 5-aza-2′-deoxycytidine increases CD8 responsiveness and induces Th1 polarity

Arginase I Production in the Tumor Microenvironment by Mature Myeloid Cells Inhibits T-Cell Receptor Expression and Antigen-Specific T-Cell Responses

Extra-Lymphatic Solid Tumor Growth Is Not Immunologically Ignored and Results in Early Induction of Antigen-Specific T-Cell Anergy: Dominant Role of Cross-Tolerance to Tumor Antigens

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