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Edi Brogi
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Journal Articles

Abstract P4-02-14: Gain of HER2 Amplification in Patients with HR+/HER2- and Triple Negative Early Breast Cancer Treated with Neoadjuvant Chemotherapy

Emanuela Ferraro, Sonya Chew Minmin, Anton Safonov, Andrea V. Barrio, Shanu Modi, Andrew D Seidman, Hanna Y Wen, Edi Brogi, Mark E. Robson, Chau T Dang
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P4-02-14.
https://doi.org/10.1158/1538-7445.SABCS22-P4-02-14
Published: 01 March 2023
View article titled, Abstract P4-02-14: Gain of HER2 Amplification in Patients with HR+/HER2- and Triple Negative Early Breast Cancer Treated with Neoadjuvant Chemotherapy
Journal Articles

Abstract 1928: Prediction of neoadjuvant treatment outcomes with multimodal data integration in breast cancer

Pegah Khosravi, Elizabeth J. Sutton, Justin Jee, Timothy Dalfonso, Christopher J. Fong, Doori Rose, Edaise M. Da Silva, Armaan Kohli, David Joon Ho, Mehnaj S. Ahmed, Danny Martinez, Anika Begum, Elizabeth Zakszewski, Andrew Aukerman, Yanis Tazi, Katja Pinker-Domenig, Sarah Eskreis-Winkler, Atif J. Khan, Edi Brogi, Elizabeth Morris, Sarat Chandarlapaty, George Plitas, Simon Powell, Monica Morrow, Larry Norton, Jianjiong Gao, Mark Robson, Hong Zhang, Sohrab Shah, Pedram Razavi, MSK-MIND Consortium
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1928.
https://doi.org/10.1158/1538-7445.AM2022-1928
Published: 15 June 2022
View article titled, Abstract 1928: Prediction of neoadjuvant treatment outcomes with multimodal data integration in breast cancer
Journal Articles

Abstract PD11-01: An artificial intelligence-based predictor of CDH1 biallelic mutations and invasive lobular carcinoma

Jorge S Reis-Filho, Fresia Pareja, Fatemeh Derakhshan, David N Brown, Jillian Sue, Pier Selenica, Yi Kan Wang, Arnaud Da Cruz Paula, Monami Banerjee, Zahra Ebrahimzadeh, Manuel Isava, Matthew Lee, Ran Godrich, Adam Casson, Ruben Padron, George Shaikovski, Alexander van Eck, Antonio Marra, Higinio Dopeso, Hannah Y Wen, Edi Brogi, Matthew G Hanna, Chris Kanan, Jeremy D Kunz, Felipe C Geyer, Carla Leibowitz, David Klimstra, Leo Grady, Thomas J Fuchs
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): PD11-01.
https://doi.org/10.1158/1538-7445.SABCS21-PD11-01
Published: 15 February 2022
View article titled, Abstract PD11-01: An artificial intelligence-based predictor of CDH1 biallelic mutations and invasive lobular carcinoma
Journal Articles

Abstract PD14-03: Genetic and epigenetic basis of invasive lobular carcinomas lacking CDH1-alterations

Fatemeh Derakhshan, Higinio Dopeso, Arnaud Da Cruz Paula, Pier Selenica, Antonio Marra, Edaise M da Silva, Andrea Gazzo, Shirin Issa Bhaloo, Dara S Ross, Anne Grabenstetter, Sarat Chandarlapaty, Pedram Razavi, Hannah Y. Wen, Hong Zhang, Edi Brogi, Britta Weigelt, Fresia Pareja, Jorge S. Reis-Filho
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): PD14-03.
https://doi.org/10.1158/1538-7445.SABCS21-PD14-03
Published: 15 February 2022
View article titled, Abstract PD14-03: Genetic and epigenetic basis of invasive lobular carcinomas lacking <em>CDH1</em>-alterations
Journal Articles

Abstract P2-13-06: Clinical implication of HER2 status change after neoadjuvant chemotherapy with Trastuzumab and Pertuzumab (HP) in patients with HER2-positive breast cancer

Emanuela Ferraro, Anton Safonov, Hanna Y Wen, Edi Brogi, Mithat Gonan, Andrea V. Barrio, Pedram Razavi, Sarat Chandarlapaty, Shanu Modi, Andrew D. Seidman, Larry Norton, Mark E. Robson, Chau T. Dang
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P2-13-06.
https://doi.org/10.1158/1538-7445.SABCS21-P2-13-06
Published: 15 February 2022
View article titled, Abstract P2-13-06: Clinical implication of HER2 status change after neoadjuvant chemotherapy with Trastuzumab and Pertuzumab (HP) in patients with HER2-positive breast cancer
Journal Articles

Abstract PD8-06: The genomic landscape of metastatic special histologic types of breast cancer

Fresia Pareja, Simon SK Lee, Francisco Beca, Lorenzo Ferrando, Pier Selenica, David N Brown, Hannah Y Wen, Hong Zhang, Edi Brogi, Pedram Razavi, Sarat Chandarlapaty, Britta Weigelt, Jorge S Reis-Filho
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): PD8-06.
https://doi.org/10.1158/1538-7445.SABCS19-PD8-06
Published: 15 February 2020
View article titled, Abstract PD8-06: The genomic landscape of metastatic special histologic types of breast cancer
Journal Articles

Abstract P4-05-11: Methylation profiling of mucinous breast cancer

Fresia Pareja, Lorenzo Ferrando, Edaise M da Silva, Arnaud Da Cruz Paula, Anthe Stylianou, David N Brown, Pier Selenica, Jonathan Serrano, Hannah Y Wen, Hong Zhang, Edi Brogi, Larry Norton, Matjia Snuderl, Jorge S Reis-Filho, Britta Weigelt
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P4-05-11.
https://doi.org/10.1158/1538-7445.SABCS19-P4-05-11
Published: 15 February 2020
View article titled, Abstract P4-05-11: Methylation profiling of mucinous breast cancer
Journal Articles

Abstract 4413: CDK6 overexpression promotes resistance to CDK4/6 inhibitors in breast cancer

Qing Li, Pedram Razavi, Zhiqiang Li, Arnaud F. Da Cruz Paula, Edi Brogi, Maurizio Scaltriti, Jorge S. Reis-Filho, Sarat Chandarlapaty
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4413.
https://doi.org/10.1158/1538-7445.AM2019-4413
Published: 01 July 2019
View article titled, Abstract 4413: CDK6 overexpression promotes resistance to CDK4/6 inhibitors in breast cancer
Journal Articles

IDH2 Mutations Define a Unique Subtype of Breast Cancer with Altered Nuclear Polarity

Sarah Chiang, Britta Weigelt, Huei-Chi Wen, Fresia Pareja, Ashwini Raghavendra, Luciano G. Martelotto, Kathleen A. Burke, Thais Basili, Anqi Li, Felipe C. Geyer, Salvatore Piscuoglio, Charlotte K.Y. Ng, Achim A. Jungbluth, Jörg Balss, Stefan Pusch, Gabrielle M. Baker, Kimberly S. Cole, Andreas von Deimling, Julie M. Batten, Jonathan D. Marotti, Hwei-Choo Soh, Benjamin L. McCalip, Jonathan Serrano, Raymond S. Lim, Kalliopi P. Siziopikou, Song Lu, Xiaolong Liu, Tarek Hammour, Edi Brogi, Matija Snuderl, A. John Iafrate, Jorge S. Reis-Filho, Stuart J. Schnitt
Journal: Cancer Research
Cancer Res (2016) 76 (24): 7118–7129.
https://doi.org/10.1158/0008-5472.CAN-16-0298
Published: 15 December 2016
View article titled, <em>IDH2</em> Mutations Define a Unique Subtype of Breast Cancer with Altered Nuclear Polarity
Open the PDF for <em>IDH2</em> Mutations Define a Unique Subtype of Breast Cancer with Altered Nuclear Polarity in another window
Includes: Supplementary data
Journal Articles

Abstract 2107: PDK1 blockade overcomes intrinsic resistance to PI3Kα inhibition

Pau Castel, Haley Ellis, Ruzica Bago, Eneda Toska, Kannan Srinivasaraghavan, F Javier Carmona, Pedram Razavi, Chandra Verma, Maura Dickler, Sarat Chandarlapaty, Edi Brogi, Dario Alessi, José Baselga, Maurizio Scaltriti
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2107.
https://doi.org/10.1158/1538-7445.AM2016-2107
Published: 15 July 2016
View article titled, Abstract 2107: PDK1 blockade overcomes intrinsic resistance to PI3Kα inhibition
Journal Articles

Abstract 138: Solid papillary carcinoma with reverse polarization are driven by IDH2 and PI3K pathway mutations

Sarah Chiang, Britta Weigelt, Huei-Chi Wen, Salvatore Piscuoglio, Luciano G. Martelotto, Charlotte K Y Ng, Jörg Balss, Gabrielle Baker, Kimberly S. Cole, Andreas von Deimling, Julie M. Batten, Jonathan D. Marotti, Hwei-Choo Soh, Benjamin L. McCalip, Raymond S. Lim, Kalliopi P. Siziopikou, Randi Burke, Song Lu, Xiaolong Liu, Tarek Hammour, Edi Brogi, A John Iafrate, Jorge S. Reis-Filho, Stuart J. Schnitt
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 138.
https://doi.org/10.1158/1538-7445.AM2016-138
Published: 15 July 2016
View article titled, Abstract 138: Solid papillary carcinoma with reverse polarization are driven by IDH2 and PI3K pathway mutations
Journal Articles

Abstract 100: The landscape of somatic genetic alterations in BRCA1 and BRCA2 breast cancers

Gabriel S. Macedo, Kathleen A. Burke, Salvatore Piscuoglio, Charlotte K. Y. Ng, Felipe C. Geyer, Luciano G. Martelotto, Anastasios D. Papanastatiou, Maria R. De Filippo, Anne M. Schultheis, Edi Brogi, Mark E. Robson, Hannah Y. Wen, Britta Weigelt, Jorge S. Reis-Filho
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 100.
https://doi.org/10.1158/1538-7445.AM2016-100
Published: 15 July 2016
View article titled, Abstract 100: The landscape of somatic genetic alterations in BRCA1 and BRCA2 breast cancers
Journal Articles

Abstract PR11: Differentiation of mammary tumors and reduction in metastasis upon Malat1 LncRNA loss

Gayatri Arun, Sarah Diermeier, Martin Akerman, Kung-Chi Chang, J.Erby Wilkinson, Stephen Hearn, Youngsoo Kim, A.Robert MacLeod, Adrian R. Krainer, Larry Norton, Edi Brogi, Mikala Egeblad, David L. Spector
Journal: Cancer Research
Cancer Res (2016) 76 (6_Supplement): PR11.
https://doi.org/10.1158/1538-7445.NONRNA15-PR11
Published: 13 May 2016
View article titled, Abstract PR11: Differentiation of mammary tumors and reduction in metastasis upon Malat1 LncRNA loss
Journal Articles

Abstract PD1-4: Somatic leukemogenic mutations associated with infiltrating white blood cells in breast cancer patients

Elizabeth A Comen, Maria Kleppe, Hannah Wen, Britta Weigelt, Lennart Bastian, Brian Blum, Franck T Rapaport, Matt Keller, Nicolas Socci, Agnes Viale, Daoqi You, Robert Benezra, Edi Brogi, Jorge Reis-Filho, Michael Berger, Ross Levine, Larry Norton
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): PD1-4.
https://doi.org/10.1158/1538-7445.SABCS14-PD1-4
Published: 01 May 2015
View article titled, Abstract PD1-4: Somatic leukemogenic mutations associated with infiltrating white blood cells in breast cancer patients
Journal Articles

Abstract S6-06: The genomic landscape of male breast cancers

Salvatore Piscuoglio, Melissa Murray, Charlotte KY Ng, Elena Guerini Rocco, Luciano G Martelotto, Francois-Clement Bidard, Carey A Eberle, Nicola Fusco, Rita A Sakr, Leticia De Mattos-Arruda, Raymond Lim, Timour Baslan, James Hicks, Tari A King, Edi Brogi, Larry Norton, Britta Weigelt, Clifford A Hudis, Jorge S Reis-Filho
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): S6-06.
https://doi.org/10.1158/1538-7445.SABCS14-S6-06
Published: 01 May 2015
View article titled, Abstract S6-06: The genomic landscape of male breast cancers
Journal Articles

Abstract P2-15-01: Integrated immunologic assessment of tumor infiltrating lymphocytes (TILs) and peripheral blood to assess synergy of cryoablation (cryo) plus ipilimumab (ipi) in early stage breast cancer (ESBC) patients (pts)

David Page, Jianda Yuan, Adi Diab, Zhiwan Dong, Arielle Ginsberg, Phillip Wong, Ryan Emerson, David Redmond, Brian Blum, Zhenyu Mu, Chunjun Zhao, Christopher Comstock, Elizabeth Morris, Elizabeth Comen, Alan Kotin, Janice Sung, Edi Brogi, Monica Morrow, Stephen Solomon, Virgilio Sacchini, Majid Maybody, Deirdre Neville, Harlan Robins, Sujata Patil, Jedd Wolchok, Clifford Hudis, Larry Norton, James Allison, Padmanee Sharma, Heather McArthur
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P2-15-01.
https://doi.org/10.1158/1538-7445.SABCS14-P2-15-01
Published: 01 May 2015
View article titled, Abstract P2-15-01: Integrated immunologic assessment of tumor infiltrating lymphocytes (TILs) and peripheral blood to assess synergy of cryoablation (cryo) plus ipilimumab (ipi) in early stage breast cancer (ESBC) patients (pts)
Journal Articles

Abstract P1-04-03: Prognostic and predictive implications of monosomy 17 in curable HER2-amplified breast cancer

David Page, Yong H Wen, Dana Dure, Clifford Hudis, Edi Brogi, Heather McArthur
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P1-04-03.
https://doi.org/10.1158/1538-7445.SABCS14-P1-04-03
Published: 01 May 2015
View article titled, Abstract P1-04-03: Prognostic and predictive implications of monosomy 17 in curable HER2-amplified breast cancer
Journal Articles

Abstract P2-03-08: Mutational landscape of metaplastic breast carcinomas

Charlotte KY Ng, Britta Weigelt, Salvatore Piscuoglio, Y Hannah Wen, Maria R De Filippo, Luciano G Martelotto, Rachael Natrajan, Raymond Lim, Edi Brogi, Larry Norton, Anne Vincent-Salomon, Jorge S Reis-Filho
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P2-03-08.
https://doi.org/10.1158/1538-7445.SABCS14-P2-03-08
Published: 01 May 2015
View article titled, Abstract P2-03-08: Mutational landscape of metaplastic breast carcinomas
Journal Articles

Abstract IA18: A brain metastasis-promoting role for cathepsin S identified from analysis of tumor- and stroma-supplied proteolytic networks

Lisa Sevenich, Robert Bowman, Steve Mason, Daniela Quail, Franck Rapaport, Benelita Elie, Edi Brogi, Priscilla Brastianos, William Hahn, Leslie Holsinger, Joan Massagué, Christina Leslie, Johanna A. Joyce
Journal: Cancer Research
Cancer Res (2015) 75 (1_Supplement): IA18.
https://doi.org/10.1158/1538-7445.CHTME14-IA18
Published: 12 January 2015
View article titled, Abstract IA18: A brain metastasis-promoting role for cathepsin S identified from analysis of tumor- and stroma-supplied proteolytic networks
Journal Articles

Abstract 2499: Application of a multiplexed fluorescence microscopy method (MultiOmyxTM) to dissect proteomic biomarkers of (18)F-fluorodeoxy-glucose ((18)FDG) uptake in breast cancer

Anup Sood, Alexandra M. Miller, Fiona Ginty, Elizabeth McDonough, Yunxia Sui, Alexander Bordwell, Qing Li, Sireesha Kaanumalle, Zhengyu Pang, Franklin Torres, Edi Brogi, Steven Larson, Ingo Mellinghoff
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2499.
https://doi.org/10.1158/1538-7445.AM2014-2499
Published: 01 October 2014
View article titled, Abstract 2499: Application of a multiplexed fluorescence microscopy method (MultiOmyx<sup>TM</sup>) to dissect proteomic biomarkers of (18)F-fluorodeoxy-glucose ((18)FDG) uptake in breast cancer