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Eddy Pasquier
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Journal Articles

ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma

Evangeline R. Jackson, Ryan J. Duchatel, Dilana E. Staudt, Mika L. Persson, Abdul Mannan, Sridevi Yadavilli, Sarah Parackal, Shaye Game, Wai Chin Chong, W. Samantha N. Jayasekara, Marion Le Grand, Padraic S. Kearney, Alicia M. Douglas, Izac J. Findlay, Zacary P. Germon, Holly P. McEwen, Tyrone S. Beitaki, Adjanie Patabendige, David A. Skerrett-Byrne, Brett Nixon, Nathan D. Smith, Bryan Day, Neevika Manoharan, Sumanth Nagabushan, Jordan R. Hansford, Dinisha Govender, Geoff B. McCowage, Ron Firestein, Meegan Howlett, Raelene Endersby, Nicholas G. Gottardo, Frank Alvaro, Sebastian M. Waszak, Martin R. Larsen, Yolanda Colino-Sanguino, Fatima Valdes-Mora, Andria Rakotomalala, Samuel Meignan, Eddy Pasquier, Nicolas André, Esther Hulleman, David D. Eisenstat, Nicholas A. Vitanza, Javad Nazarian, Carl Koschmann, Sabine Mueller, Jason E. Cain, Matthew D. Dun
Journal: Cancer Research
Cancer Res (2023) 83 (14): 2421–2437.
https://doi.org/10.1158/0008-5472.CAN-23-0186
Published: 14 July 2023
View articletitled, ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma
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Includes: Supplementary data
Journal Articles

Abstract 1671: Engineering new cellular models to decipher H3.3K27M mutation role in DIPGs' resistance to therapies

Andria Rakotomalala, Paul Lewandowski, Quentin Bailleul, Clara Savary, Mélanie Arcicasa, Christine Bal, Maud Hamadou, Paul Huchedé, Audrey Restouin, Remy Castellano, Yves Collette, Audrey Vincent, Pierre-Olivier Angrand, Eric Adriaenssens, Xuefen Le Bourhis, Pierre Leblond, Marie Castets, Eddy Pasquier, Alessandro Furlan, Samuel Meignan
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1671.
https://doi.org/10.1158/1538-7445.AM2022-1671
Published: 15 June 2022
View articletitled, Abstract 1671: Engineering new cellular models to decipher H3.3K27M mutation role in DIPGs' resistance to therapies
Journal Articles

Abstract 5005: Impact of H3.3K27M mutation on diffuse intrinsic pontine glioma's resistance to treatment

Quentin Bailleul, Mélanie Arcicasa, Audrey Hochart, Andria Rakotomalala, Marie Castets, Eddy Pasquier, Pierre-Olivier Angrand, Eric Adriaenssens, Xuefen Le Bourhis, Pierre Leblond, Samuel Meignan
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5005.
https://doi.org/10.1158/1538-7445.AM2020-5005
Published: 15 August 2020
View articletitled, Abstract 5005: Impact of H3.3K27M mutation on diffuse intrinsic pontine glioma's resistance to treatment
Journal Articles

Pharmacokinetics and Pharmacodynamics-Based Mathematical Modeling Identifies an Optimal Protocol for Metronomic Chemotherapy

Joseph Ciccolini, Dominique Barbolosi, Christophe Meille, Aurélie Lombard, Cindy Serdjebi, Sarah Giacometti, Laetitia Padovani, Eddy Pasquier, Nicolas André
Journal: Cancer Research
Cancer Res (2017) 77 (17): 4723–4733.
https://doi.org/10.1158/0008-5472.CAN-16-3130
Published: 31 August 2017
View articletitled, Pharmacokinetics and Pharmacodynamics-Based Mathematical Modeling Identifies an Optimal Protocol for Metronomic Chemotherapy
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Includes: Supplementary data
Journal Articles

Abstract 4506: Computational-driven metronomics: application to gemcitabine in neuroblastoma-bearing mice

Joseph Ciccolini, Eddy Pasquier, Aurelie Lombard, Sarah Giacometti, Christian Faivre, Raphaelle Fanciullino, Cindy Serdjebi, Dominique Barbolosi, Nicolas Andre
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4506.
https://doi.org/10.1158/1538-7445.AM2015-4506
Published: 01 August 2015
View articletitled, Abstract 4506: Computational-driven metronomics: application to gemcitabine in neuroblastoma-bearing mice
Journal Articles

Abstract 2572: Metronomic scheduling: a promising strategy to manage intratumor heterogeneity and control treatment resistance

Manon Carre, Maryna Bondarenko, Marie-Pierre Montero, Guillemette Chapuisat, Assia Benabdallah, Marion Le Grand, Diane Braguer, Nicolas Andre, Eddy Pasquier
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2572.
https://doi.org/10.1158/1538-7445.AM2015-2572
Published: 01 August 2015
View articletitled, Abstract 2572: Metronomic scheduling: a promising strategy to manage intratumor heterogeneity and control treatment resistance
Journal Articles

Formalizing an Integrative, Multidisciplinary Cancer Therapy Discovery Workflow

Mary F. McGuire, Heiko Enderling, Dorothy I. Wallace, Jaspreet Batra, Marie Jordan, Sushil Kumar, John C. Panetta, Eddy Pasquier
Journal: Cancer Research
Cancer Res (2013) 73 (20): 6111–6117.
https://doi.org/10.1158/0008-5472.CAN-13-0310
Published: 14 October 2013
View articletitled, Formalizing an Integrative, Multidisciplinary Cancer Therapy Discovery Workflow
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Journal Articles

Abstract 2985: The histone demethylase JMJD1A induces neuroblastoma cell migration and invasion.

Dora Ling, Andrew Tee, Charlotte Nelson, Ning Xu, Bernard Atmadibrata, Pei Y. Liu, Eddy Pasquier, Glenn M. Marshall, Takayoshi Suzuki, Yi Zhang, Tao Liu
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2985.
https://doi.org/10.1158/1538-7445.AM2013-2985
Published: 15 April 2013
View articletitled, Abstract 2985: The histone demethylase JMJD1A induces neuroblastoma cell migration and invasion.
Journal Articles

Abstract 2555: Drug repositioning: Propanolol potentiates the anticancer efficacy of chemotherapeutic agents through modulation of angiogenesis

Joseph Ciccolini, Eddy Pasquier, Raphaelle Fanciullino, Cindy Serdjebi, Cecilia Mas, Sarah Giacometti, Maria Kavallaris, Nicolas André
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2555.
https://doi.org/10.1158/1538-7445.AM2011-2555
Published: 15 April 2011
View articletitled, Abstract 2555: Drug repositioning: Propanolol potentiates the anticancer efficacy of chemotherapeutic agents through modulation of angiogenesis
Journal Articles

Abstract 1110: Molecular and functional alterations associated with repression of tumor suppressor p16INK4a during immortalization of human endothelial cells

Victoria W. Wen, Flora Kan, Eddy Pasquier, Melissa Chang, Maria Kavallaris, Karen L. Mackenzie
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1110.
https://doi.org/10.1158/1538-7445.AM10-1110
Published: 15 April 2010
View articletitled, Abstract 1110: Molecular and functional alterations associated with repression of tumor suppressor p16INK4a during immortalization of human endothelial cells
Journal Articles

Abstract LB-368: III-tubulin knockdown in endothelial cells increases the antivascular activity of chemotherapeutic drugs

Eddy Pasquier, Snega Sinnappan, Pascal Verdier-Pinard, Diane Braguer, Maria Kavallaris
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): LB-368.
https://doi.org/10.1158/1538-7445.AM10-LB-368
Published: 15 April 2010
View articletitled, Abstract LB-368: III-tubulin knockdown in endothelial cells increases the antivascular activity of chemotherapeutic drugs
Journal Articles

Abstract 4418: ENMD-1198, a new microtubule-targeting agent with potent anti-vascular properties

Eddy Pasquier, Snega Sinnappan, Marcia Munoz, Maria Kavallaris
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4418.
https://doi.org/10.1158/1538-7445.AM10-4418
Published: 15 April 2010
View articletitled, Abstract 4418: ENMD-1198, a new microtubule-targeting agent with potent anti-vascular properties
Journal Articles

Class III β-Tubulin Mediates Sensitivity to Chemotherapeutic Drugs in Non–Small Cell Lung Cancer

Pei Pei Gan, Eddy Pasquier, Maria Kavallaris
Journal: Cancer Research
Cancer Res (2007) 67 (19): 9356–9363.
https://doi.org/10.1158/0008-5472.CAN-07-0509
Published: 01 October 2007
View articletitled, Class III β-Tubulin Mediates Sensitivity to Chemotherapeutic Drugs in Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Anti-angiogenic effect of vinflunine is associated with altered microtubule dynamics and focal adhesion turnover

Stephane honore, Karine Civiletti, Eddy Pasquier, Bertrand Pourroy, Veronique Bourgarel-Rey, Anna Kruczynski, Diane Braguer
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 3986.
Published: 01 May 2007
View articletitled, Anti-angiogenic effect of vinflunine is associated with altered microtubule dynamics and focal adhesion turnover
Journal Articles

High level of     β     II-tubulin expression and large pool of soluble tubulin in human vascular endothelial cells

Eddy Pasquier, Pascal Verdier-Pinard, Daniel Lafitte, Claude Villard, Huyen Cao, Francois Devred, Susan Horwitz, Diane Braguer
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 5624.
Published: 01 May 2007
View articletitled, High level of     β     II-tubulin expression and large pool of soluble tubulin in human vascular endothelial cells
Journal Articles

Increase in interphase microtubule dynamics by vinflunine inhibited angiogenesis by disturbing endothelial cell morphogenesis and motility

Bertrand Pourroy, Eddy Pasquier, Stéphane Honore, Véronique Bourgarel-Rey, Anna Kruczynski, Claudette Briand, Diane Braguer
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 115–116.
Published: 15 April 2006
View articletitled, Increase in interphase microtubule dynamics by vinflunine inhibited angiogenesis by disturbing endothelial cell morphogenesis and motility
Journal Articles

Antiangiogenic Concentrations of Vinflunine Increase the Interphase Microtubule Dynamics and Decrease the Motility of Endothelial Cells

Bertrand Pourroy, Stéphane Honoré, Eddy Pasquier, Véronique Bourgarel-Rey, Anna Kruczynski, Claudette Briand, Diane Braguer
Journal: Cancer Research
Cancer Res (2006) 66 (6): 3256–3263.
https://doi.org/10.1158/0008-5472.CAN-05-3885
Published: 15 March 2006
View articletitled, Antiangiogenic Concentrations of Vinflunine Increase the Interphase Microtubule Dynamics and Decrease the Motility of Endothelial Cells
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Includes: Supplementary data
Journal Articles

Inhibition of angiogenesis by vinflunine is associated with an increase in microtubule dynamics in living endothelial cells

Bertrand Pourroy, Stéphane Honore, Eddy Pasquier, Véronique Bourgarel-Rey, Anna Kruczynski, Claudette Briand, Diane Braguer
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 809–810.
Published: 01 May 2005
View articletitled, Inhibition of angiogenesis by vinflunine is associated with an increase in microtubule dynamics in living endothelial cells
Journal Articles

Antiangiogenic Concentrations of Paclitaxel Induce an Increase in Microtubule Dynamics in Endothelial Cells but Not in Cancer Cells

Eddy Pasquier, Stéphane Honore, Bertrand Pourroy, Mary Ann Jordan, Maxime Lehmann, Claudette Briand, Diane Braguer
Journal: Cancer Research
Cancer Res (2005) 65 (6): 2433–2440.
https://doi.org/10.1158/0008-5472.CAN-04-2624
Published: 21 March 2005
View articletitled, Antiangiogenic Concentrations of Paclitaxel Induce an Increase in Microtubule Dynamics in Endothelial Cells but Not in Cancer Cells
Open the PDF for Antiangiogenic Concentrations of Paclitaxel Induce an Increase in Microtubule Dynamics in Endothelial Cells but Not in Cancer Cells in another window