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E. Anders Kolb
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Journal Articles

Abstract 7040: The B7-H3 targeting antibody-drug conjugate (ADC) vobramitamab duocarmazine (vobra duo) is potently effective against a broad panel of pediatric solid tumor xenograft models: A study from the Pediatric Preclinical In Vivo Testing (PIVOT) Consortium

Free
Haiying Tang, Edward Favours, Samson Ghilu, Peyton Wong, Vanessa Del Pozo, Abhik Bandyopadhyay, Elena Mironova, Eric J. Earley, Stephen W. Erickson, David Groff, Beverly A. Teicher, Kateryna Krytska, Matthew Tsang, Yael P. Mosse, E. Anders Kolb, Matthew Stephens, Steve Neuhauser, Tim Stearns, Jeff Chuang, Emily L. Jocoy, Jee Young Kwon, Carol Bult, Malcolm A. Smith, John M. Maris, Richard G. Gorlick, Peter J. Houghton, Raushan Kurmasheva
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 7040.
https://doi.org/10.1158/1538-7445.AM2025-7040
Published: 21 April 2025
View articletitled, Abstract 7040: The B7-H3 targeting antibody-drug conjugate (ADC) vobramitamab duocarmazine (vobra duo) is potently effective against a broad panel of pediatric solid tumor xenograft models: A study from the Pediatric Preclinical In Vivo Testing (PIVOT) Consortium
Journal Articles

Abstract LB061: Evaluation of the in vivo efficacy of the B7-H3 targeting antibody-drug conjugate (ADC) DS7300a: A report fro the Pediatric Preclinical In Vivo Resting (PIVOT) program

Free
Richard Gorlick, E. Anders Kolb, Yifei Wang, Peter Houghton, Raushan Kurmasheva, Yael Mosse, John Maris, Matthew Tsang, David Groff, Kateryna Krytska, Xiao-Nan Li, Yuchen Du, Jun Hasegawa, Nanae Izumi, Steven Neuhauser, Anuj Srivastava, Tim Stearns, Vivek Philip, Emily L. Jocoy, Jeff Chuang, Carol J. Bult, Beverly Teicher, Malcolm Smith
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): LB061.
https://doi.org/10.1158/1538-7445.AM2022-LB061
Published: 15 June 2022
View articletitled, Abstract LB061: Evaluation of the in vivo efficacy of the B7-H3 targeting antibody-drug conjugate (ADC) DS7300a: A report fro the Pediatric Preclinical In Vivo Resting (PIVOT) program
Journal Articles

Abstract 3479: UBTF tandem duplications (UBTF-TD) in childhood AML: Enrichment in FLT3-ITD and association with clinical outcome

Free
Leila Robinson, Amanda Leonti, Todd A. Alonzo, Yi-Cheng Wang, Michele S. Redell, Rhonda E. Ries, Jenny L. Smith, Tiffany A. Hylkema, Quy Le, E Anders Kolb, Richard Aplenc, Xiaotu Ma, Jeffrey Klco, Katherine Tarlock, Soheil Meshinchi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3479.
https://doi.org/10.1158/1538-7445.AM2022-3479
Published: 15 June 2022
View articletitled, Abstract 3479: UBTF tandem duplications (UBTF-TD) in childhood AML: Enrichment in FLT3-ITD and association with clinical outcome
Journal Articles

Abstract LB-322: Identification of a novel fusion protein SPTAN1-ABL1 in a child with T-cell acute lymphoblastic leukemia: Functional characterization and therapeutic implications

Free
Anilkumar Gopalakrisnapillai, Erin Crowgey, Demetria Ruhl, Darcy Hamill, Nitin Mahajan, Todd Druley, E. Anders Kolb, Sonali P. Barwe
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-322.
https://doi.org/10.1158/1538-7445.AM2019-LB-322
Published: 01 July 2019
View articletitled, Abstract LB-322: Identification of a novel fusion protein SPTAN1-ABL1 in a child with T-cell acute lymphoblastic leukemia: Functional characterization and therapeutic implications
Journal Articles

Abstract 2870: Genetic mechanisms of primary chemotherapy resistance in pediatric acute myeloid leukemia

Free
Nicole McNeer, John Philip, Heather Geiger, Rhonda E. Ries, Vincent-Philippe Lavallee, Michael Walsh, Minita Shah, Kanika Arora, Anne-Katrin Emde, Nicolas Robine, Todd A. Alonzo, E. Anders Kolb, Alan S. Gamis, Malcom Smith, Daniela Se Gerhard, Jaime Guidry-Auvil, Soheil Meshinchi, Alex Kentsis
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2870.
https://doi.org/10.1158/1538-7445.AM2019-2870
Published: 01 July 2019
View articletitled, Abstract 2870: Genetic mechanisms of primary chemotherapy resistance in pediatric acute myeloid leukemia
Journal Articles

Abstract 5872: Pediatric Preclinical Testing Consortium (PPTC) of eribulin in osteosarcoma (OS) patient-derived xenograft (PDX) models

Free
Wendong Zhang, E. Anders Kolb, Richard Gorlick, Michael Roth, Jonathan Gill, Sudie Rowshan, Stephen Erickson, Raushan Kurmasheva, Peter Houghton, Beverly Teicher, Malcolm A. Smith
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5872.
https://doi.org/10.1158/1538-7445.AM2018-5872
Published: 01 July 2018
View articletitled, Abstract 5872: Pediatric Preclinical Testing Consortium (PPTC) of eribulin in osteosarcoma (OS) patient-derived xenograft (PDX) models
Journal Articles

Abstract 2076: Identification of novel fusion genes and expression variants in primary and patient-derived xenograft samples of pediatric leukemia using error-corrected RNA sequencing

Free
Sonali P. Barwe, Anilkumar Gopalakrishnapillai, Nitin Mahajan, Todd Druley, E. Anders Kolb, Erin L. Crowgey
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2076.
https://doi.org/10.1158/1538-7445.AM2018-2076
Published: 01 July 2018
View articletitled, Abstract 2076: Identification of novel fusion genes and expression variants in primary and patient-derived xenograft samples of pediatric leukemia using error-corrected RNA sequencing
Journal Articles

Abstract 2699: Proteomic landscape of de novo pediatric acute myeloid leukemia

Free
Fieke W. Hoff, Yihua Qiu, Wendy Hu, Amina A. Qutub, Alan S. Gamis, Richard Aplenc, E Anders Kolb, Todd A. Alonzo, Eveline SJM de Bont, Terzah M. Horton, Steven M. Kornblau
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2699.
https://doi.org/10.1158/1538-7445.AM2018-2699
Published: 01 July 2018
View articletitled, Abstract 2699: Proteomic landscape of de novo pediatric acute myeloid leukemia
Journal Articles

Abstract 451: Proteomic profiling of the unfolded protein response identifies patients benefiting from bortezomib in pediatric acute myeloid leukemia

Free
Fieke W. Hoff, Yihua Qiu, Wendy Hu, Amina A. Qutub, Alon S. Gamis, Richard Aplenc, E Anders Kolb, Todd A. Alonzo, Eveline SJM de Bont, Steven M. Kornblau, Terzah Horton
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 451.
https://doi.org/10.1158/1538-7445.AM2018-451
Published: 01 July 2018
View articletitled, Abstract 451: Proteomic profiling of the unfolded protein response identifies patients benefiting from bortezomib in pediatric acute myeloid leukemia
Journal Articles

Abstract 697: Stage 1 in vivo evaluation of multi-receptor tyrosine-kinase inhibitor lenvatinib in osteosarcoma patient derived mouse xenograft models

Free
Wendong Zhang, Michael E. Roth, Jonathan Gill, Sajida Piperdi, E. Anders Kolb, David S. Geller, Bang Hoang, Rui Yang, Richard Gorlick
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 697.
https://doi.org/10.1158/1538-7445.AM2017-697
Published: 01 July 2017
View articletitled, Abstract 697: Stage 1 in vivo evaluation of multi-receptor tyrosine-kinase inhibitor lenvatinib in osteosarcoma patient derived mouse xenograft models
Journal Articles

Evaluation of Alternative In Vivo Drug Screening Methodology: A Single Mouse Analysis

Free
Brendan Murphy, Han Yin, John M. Maris, E. Anders Kolb, Richard Gorlick, C. Patrick Reynolds, Min H. Kang, Stephen T. Keir, Raushan T. Kurmasheva, Igor Dvorchik, Jianrong Wu, Catherine A. Billups, Nana Boateng, Malcolm A. Smith, Richard B. Lock, Peter J. Houghton
Journal: Cancer Research
Cancer Res (2016) 76 (19): 5798–5809.
https://doi.org/10.1158/0008-5472.CAN-16-0122
Published: 02 October 2016
View articletitled, Evaluation of Alternative In Vivo Drug Screening Methodology: A Single Mouse Analysis
Open the PDF for Evaluation of Alternative In Vivo Drug Screening Methodology: A Single Mouse Analysis in another window
Includes: Supplementary data
Journal Articles

Abstract 1616: Pharmacodynamic and genomic markers associated with response to the XPO1/CRM1 inhibitor selinexor (KPT-330): a report from the Pediatric Preclinical Testing Program

Free
Malcolm A. Smith, Richard Lock, Hernan Carol, John M. Maris, Richard Gorlick, E. Anders Kolb, Stephen T. Keir, Jianrong Wu, Yosef Landesman, Sharon Shacham, Dmitry Lyalin, Raushan T. Kurmasheva, Peter J. Houghton
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1616.
https://doi.org/10.1158/1538-7445.AM2015-1616
Published: 01 August 2015
View articletitled, Abstract 1616: Pharmacodynamic and genomic markers associated with response to the XPO1/CRM1 inhibitor selinexor (KPT-330): a report from the Pediatric Preclinical Testing Program
Journal Articles

Abstract LB-213: Combination of epigenetic modifiers achieves complete remission in xenograft models of pediatric acute myeloid leukemia

Free
Anilkumar Gopalakrishnapillai, E Anders Kolb, Sonali P. Barwe
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): LB-213.
https://doi.org/10.1158/1538-7445.AM2015-LB-213
Published: 01 August 2015
View articletitled, Abstract LB-213: Combination of epigenetic modifiers achieves complete remission in xenograft models of pediatric acute myeloid leukemia
Journal Articles

Abstract 2754: Pediatric Preclinical Testing Program (PPTP) stage 1 evaluation of the antimicrotubule agents cabazitaxel and docetaxel.

Free
Peter J. Houghton, Min Kang, C Patrick Reynolds, Richard B. Lock, Hernan Carol, Richard Gorlick, E Anders Kolb, John M. Maris, Stephen T. Keir, Catherine A. Billups, Raushan T. Kurmasheva, Malcolm Anders Smith
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2754.
https://doi.org/10.1158/1538-7445.AM2013-2754
Published: 15 April 2013
View articletitled, Abstract 2754: Pediatric Preclinical Testing Program (PPTP) stage 1 evaluation of the antimicrotubule agents cabazitaxel and docetaxel.
Journal Articles

Abstract 4547: High-throughput screen to identify compounds targeted to embryonal rhabdomyosarcoma harboring mutant HRAS using cells derived from a pediatric Costello syndrome patient.

Free
Donna M. Cartledge, Katherine M. Drake, Karen W. Gripp, Katia Sol-Church, E. Anders Kolb, Andrew D. Napper
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4547.
https://doi.org/10.1158/1538-7445.AM2013-4547
Published: 15 April 2013
View articletitled, Abstract 4547: High-throughput screen to identify compounds targeted to embryonal rhabdomyosarcoma harboring mutant HRAS using cells derived from a pediatric Costello syndrome patient.
Journal Articles

Abstract 740: Pediatric Preclinical Testing Program (PPTP) evaluation of the NEDD8-activating enzyme (NAE) inhibitor MLN4924

Free
Hernan Carol, Richard B. Lock, John M. Maris, Stephen T. Keir, Richard Gorlick, E. Anders Kolb, Min H. Kang, C Patrick Reynolds, Christopher L. Morton, Peter G. Smith, Michael Thomas, Alice McDonald, Peter J. Houghton, Malcolm A. Smith
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 740.
https://doi.org/10.1158/1538-7445.AM2011-740
Published: 15 April 2011
View articletitled, Abstract 740: Pediatric Preclinical Testing Program (PPTP) evaluation of the NEDD8-activating enzyme (NAE) inhibitor MLN4924
Journal Articles

Abstract 5356: Pediatric preclinical testing program (PPTP) evaluation of the DNA methylating agent temozolomide

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Stephen T. Keir, Christopher L. Morton, E. Anders Kolb, Richard Gorlick, Hernan Carol, Richard Lock, Min H. Kang, C Patrick Reynolds, John M. Maris, Jianrong Wu, Malcolm A. Smith, Peter J. Houghton
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5356.
https://doi.org/10.1158/1538-7445.AM2011-5356
Published: 15 April 2011
View articletitled, Abstract 5356: Pediatric preclinical testing program (PPTP) evaluation of the DNA methylating agent temozolomide
Journal Articles

Abstract 5358: Pediatric preclinical testing program (PPTP) evaluation of the non-camptothecin topoisomerase 1 targeted agent Genz644282

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Peter J. Houghton, Richard B. Lock, Hernan Carol, Christopher L. Morton, Richard Gorlick, E. Anders Kolb, Stephen T. Kier, C. Patrick Reynolds, Min H. Kang, John M. Maris, Catherine A. Billups, Malcolm A. Smith
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5358.
https://doi.org/10.1158/1538-7445.AM2011-5358
Published: 15 April 2011
View articletitled, Abstract 5358: Pediatric preclinical testing program (PPTP) evaluation of the non-camptothecin topoisomerase 1 targeted agent Genz644282
Journal Articles

Abstract 5266: Pediatric Preclinical Testing Program (PPTP) evaluation of the CDK inhibitor SCH 727965

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Malcolm A. Smith, John M. Maris, Josh Courtright, Henry S. Friedman, Stephen T. Kier, Richard B. Lock, Hernan Carol, Richard Gorlick, E Anders Kolb, Min Kang, Christopher Patrick Reynolds, Christopher L. Morton, Peter J. Houghton
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5266.
https://doi.org/10.1158/1538-7445.AM10-5266
Published: 15 April 2010
View articletitled, Abstract 5266: Pediatric Preclinical Testing Program (PPTP) evaluation of the CDK inhibitor SCH 727965
Journal Articles

Abstract 3403: Responsiveness to IGF-1R targeted therapy in osteosarcoma may be regulated by the 3179 G>A mutation

Free
Rebecca Sowers, So-Hak Chung, Wendong Zhang, E. Anders Kolb, Richard Gorlick
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3403.
https://doi.org/10.1158/1538-7445.AM10-3403
Published: 15 April 2010
View articletitled, Abstract 3403: Responsiveness to IGF-1R targeted therapy in osteosarcoma may be regulated by the 3179 G>A mutation