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Abstract 5727: Metabolic status and adaptability of breast cancer stem cells

Johanna M. Buschhaus, Ayse J. Muniz, Ming Luo, Joseph P. Burnett, Nathan A. Truchan, Michael D. Brooks, Brock A. Humphries, Kathy E. Luker, Joerg Lahann, Duxin Sun, Max S. Wicha, Gary D. Luker

Cancer Res (2020) 80 (16_Supplement): 5727.

DOI: https://doi.org/10.1158/1538-7445.AM2020-5727

Published: 15 August 2020

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Journal Articles

Abstract 500: Discovering epigenetic regulators of cells states in triple negative breast cancers

Joseph Patrick Burnett, Garrett Johnson, Nathan Truchan, Michael Brooks, Max S. Wicha, Duxin Sun

Cancer Res (2020) 80 (16_Supplement): 500.

DOI: https://doi.org/10.1158/1538-7445.AM2020-500

Published: 15 August 2020

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Journal Articles

Abstract 3220: Enhancing breast cancer immunotherapy via IONP-mediated photothermal therapy

Hongwei Chen, Xin Luan, Hayley Paholak, Joseph Burnett, Nicholas Stevers, Kanokwan Sansanaphongpricha, Miao He, Alfred Chang, Qiao Li, Duxin Sun

Cancer Res (2019) 79 (13_Supplement): 3220.

DOI: https://doi.org/10.1158/1538-7445.AM2019-3220

Published: 01 July 2019

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Journal Articles

Abstract 968: Targeting intratumoral heterogeneity in TNBC with novel combinations of FDA-approved drugs

Nathan A. Truchan, Joseph P. Burnett, Duxin Sun

Cancer Res (2019) 79 (13_Supplement): 968.

DOI: https://doi.org/10.1158/1538-7445.AM2019-968

Published: 01 July 2019

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Journal Articles

Abstract 2004: Identification of MLK4 as a novel regulator of cancer stem cells in triple-negative breast cancer

Chang-Ching Lin, Miao-Chia Lo, Rebecca Moody, Nicholas Stevers, Samantha Tinsley, Mari Gasparyan, Max Wicha, Duxin Sun

Cancer Res (2018) 78 (13_Supplement): 2004.

DOI: https://doi.org/10.1158/1538-7445.AM2018-2004

Published: 01 July 2018

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Journal Articles

Abstract 2007: A novel CRISPR/Cas9 reporter system to monitor TNBC cancer stem cells in real time

Nathan A. Truchan, Johanna Buschhaus, Michael Brooks, Andre Halabu, Hongwei Guo, Hebao Yuan, Kathryn Luker, Max Wicha, Duxin Sun, Joseph P. Burnett

Cancer Res (2018) 78 (13_Supplement): 2007.

DOI: https://doi.org/10.1158/1538-7445.AM2018-2007

Published: 01 July 2018

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Journal Articles

Abstract 1970: Novel Mcl-1 inhibitor effectively restores in vivo regorafenib sensitivity in resistant colorectal cancer

Karson J. Kump, Jingshan Tong, Ahmed S. Mady, Lei Miao, Siwei Li, Duxin Sun, Jian Yu, Lin Zhang, Zaneta Nikolovska-Coleska

Cancer Res (2018) 78 (13_Supplement): 1970.

DOI: https://doi.org/10.1158/1538-7445.AM2018-1970

Published: 01 July 2018

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Journal Articles

Abstract LB-053: Tracing redox-regulated breast cancer stem cell state transition using a dual fluorescent reporter system

Ming Luo, Michael Brooks, Joseph Burnett, Nathan Truchan, Duxin Sun, Max S. Wicha

Cancer Res (2018) 78 (13_Supplement): LB-053.

DOI: https://doi.org/10.1158/1538-7445.AM2018-LB-053

Published: 01 July 2018

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Journal Articles

Abstract 4604: Long noncoding RNA Linc00162, as a novel prognostic marker, modulates cancer stem cell properties in triple-negative breast cancer

Lichao Sun, ChangChing Lin, Joseph Burnett, Hebao Yuan, Duxin Sun

Cancer Res (2018) 78 (13_Supplement): 4604.

DOI: https://doi.org/10.1158/1538-7445.AM2018-4604

Published: 01 July 2018

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Journal Articles

Abstract 4495: Elucidating BCL11A’s function in triple negative breast cancer

Nicholas O. Stevers, Samantha L. Tinsley, Rebecca Moody, Chang-Ching Lin, Jennifer Meagher, Jeanne A. Stuckey, Miao-Chia Lo, Duxin Sun

Cancer Res (2017) 77 (13_Supplement): 4495.

DOI: https://doi.org/10.1158/1538-7445.AM2017-4495

Published: 01 July 2017

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Journal Articles

Abstract 5077: A novel small molecule menin-MLL inhibitor for potential treatment of MLL-rearranged leukemias

Cancer Res (2017) 77 (13_Supplement): 5077.

DOI: https://doi.org/10.1158/1538-7445.AM2017-5077

Published: 01 July 2017

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Journal Articles

Abstract 5257: Cellular pharmacology of curcumin cellular pharmacology of curcumin±piperine

Rama Mahran, Pan Shu, Duxin Sun, Dean E. Brenner

Cancer Res (2017) 77 (13_Supplement): 5257.

DOI: https://doi.org/10.1158/1538-7445.AM2017-5257

Published: 01 July 2017

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Journal Articles

Abstract 940: Altering intratumoral heterogeneity in HER2+ breast cancers with PTEN inactivation and trastuzumab therapy

Joseph P. Burnett, Shamileh Fouladdel, Nathan Truchan, Ebrahim Azizi, Max Wicha, Duxin Sun

Cancer Res (2017) 77 (13_Supplement): 940.

DOI: https://doi.org/10.1158/1538-7445.AM2017-940

Published: 01 July 2017

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Journal Articles

Abstract 4788: Abraxane eliminates cancer stem cells in triple-negative breast cancers

Hebao Yuan, Hongwei Guo, Feng Li, Joseph Burnett, Miao He, Nathan Truchan, Ila Myers, Duxin Sun

Cancer Res (2017) 77 (13_Supplement): 4788.

DOI: https://doi.org/10.1158/1538-7445.AM2017-4788

Published: 01 July 2017

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Journal Articles

Abstract 4767: Identifying CDCA7 as a novel regulator of tumor-initiating cells in triple-negative breast cancer

Chang-Ching Lin, Miao-Chia Lo, Rebecca Moody, Nicholas Stevers, Samantha Tinsley, Max Wicha, Duxin Sun

Cancer Res (2017) 77 (13_Supplement): 4767.

DOI: https://doi.org/10.1158/1538-7445.AM2017-4767

Published: 01 July 2017

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Journal Articles

Abstract 5083: A novel and highly efficacious small-molecule degrader of BET-BRD proteins for the treatment of acute leukemia

Ester Fernandez-Salas, Zhuo Chen, Mei Lin, Bing Zhou, Donna McEachern, Sally Przybranowski, Karson Kump, Luke F. Peterson, Malathi Kandarpa, Jiantao Hu, Fuming Xu, Liu Liu, Longchuan Bai, Bo Wen, Duxin Sun, Moshe Talpaz, Shaomeng Wang

Cancer Res (2017) 77 (13_Supplement): 5083.

DOI: https://doi.org/10.1158/1538-7445.AM2017-5083

Published: 01 July 2017

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Journal Articles

Abstract 2002: Disrupting immunosuppressive tumor microenvironment via stealthy nanobombs to enhance T-cell anticancer efficacy

Hongwei Chen, Hayley J. Paholak, Xin Luan, Joseph P. Burnett, Nicholas O. Stevers, Kanokwan Sansanaphongpricha, Duxin Sun

Cancer Res (2017) 77 (13_Supplement): 2002.

DOI: https://doi.org/10.1158/1538-7445.AM2017-2002

Published: 01 July 2017

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Journal Articles

Targeted Degradation of BET Proteins in Triple-Negative Breast Cancer

Cancer Res (2017) 77 (9): 2476–2487.

DOI: https://doi.org/10.1158/0008-5472.CAN-16-2622

Published: 30 April 2017

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Includes: Supplementary data

Journal Articles

Abstract 2509: Determining the functional and mechanistic role of homeobox transcription factor Meox1 in breast cancer and breast cancer stem cells

Mari Gasparyan, Joseph P. Burnett, Lichao Sun, Duxin Sun

Cancer Res (2016) 76 (14_Supplement): 2509.

DOI: https://doi.org/10.1158/1538-7445.AM2016-2509

Published: 15 July 2016

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Journal Articles

Abstract 3091: Development and optimization of a fluorescence polarization-based assay for the discovery of inhibitors of the RBBP4/7-Histone H3 interaction

Rebecca Reed, Miao-Chia Lo, Chang-Ching Lin, Duxin Sun

Cancer Res (2016) 76 (14_Supplement): 3091.

DOI: https://doi.org/10.1158/1538-7445.AM2016-3091

Published: 15 July 2016

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NARROW

Abstract 5727: Metabolic status and adaptability of breast cancer stem cells

Abstract 500: Discovering epigenetic regulators of cells states in triple negative breast cancers

Abstract 3220: Enhancing breast cancer immunotherapy via IONP-mediated photothermal therapy

Abstract 968: Targeting intratumoral heterogeneity in TNBC with novel combinations of FDA-approved drugs

Abstract 2004: Identification of MLK4 as a novel regulator of cancer stem cells in triple-negative breast cancer

Abstract 2007: A novel CRISPR/Cas9 reporter system to monitor TNBC cancer stem cells in real time

Abstract 1970: Novel Mcl-1 inhibitor effectively restores in vivo regorafenib sensitivity in resistant colorectal cancer

Abstract LB-053: Tracing redox-regulated breast cancer stem cell state transition using a dual fluorescent reporter system

Abstract 4604: Long noncoding RNA Linc00162, as a novel prognostic marker, modulates cancer stem cell properties in triple-negative breast cancer

Abstract 4495: Elucidating BCL11A’s function in triple negative breast cancer

Abstract 5077: A novel small molecule menin-MLL inhibitor for potential treatment of MLL-rearranged leukemias

Abstract 5257: Cellular pharmacology of curcumin cellular pharmacology of curcumin±piperine

Abstract 940: Altering intratumoral heterogeneity in HER2+ breast cancers with PTEN inactivation and trastuzumab therapy

Abstract 4788: Abraxane eliminates cancer stem cells in triple-negative breast cancers

Abstract 4767: Identifying CDCA7 as a novel regulator of tumor-initiating cells in triple-negative breast cancer

Abstract 5083: A novel and highly efficacious small-molecule degrader of BET-BRD proteins for the treatment of acute leukemia

Abstract 2002: Disrupting immunosuppressive tumor microenvironment via stealthy nanobombs to enhance T-cell anticancer efficacy

Targeted Degradation of BET Proteins in Triple-Negative Breast Cancer

Abstract 2509: Determining the functional and mechanistic role of homeobox transcription factor Meox1 in breast cancer and breast cancer stem cells

Abstract 3091: Development and optimization of a fluorescence polarization-based assay for the discovery of inhibitors of the RBBP4/7-Histone H3 interaction

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