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Journal Articles

Abstract 2410: Supraphysiological androgens induce ferroptotic cell death in prostate cancer cells

Rajendra Kumar, Kavya Boyapati, Naiju Thomas, Deven Topiwala, Suthicha Kanacharoen, Olutosin Owoyemi, Max Coffey, Michael Carducci, Mark C. Markowski, Emmanuel S. Antonarakis, Drew Pardoll, Samuel Denmeade, Sushant K. Kachhap
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2410.
DOI: https://doi.org/10.1158/1538-7445.AM2020-2410
Published: 15 August 2020
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Journal Articles

Abstract 517: Supraphysiological androgens activate innate immune signaling in prostate cancer

Janet Mendonca, Olutosin Owoyemi, Marc Rosen, Michael Carducci, Mark Markowski, Emmanuel Antonarakis, Drew Pardoll, Samuel Denmeade, Sushant K. Kachhap
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 517.
DOI: https://doi.org/10.1158/1538-7445.AM2019-517
Published: 01 July 2019
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Abstract 1736: The combination of CXCR4 and checkpoint receptor inhibition improves survival in an orthotopic murine glioma model

Adela Wu, Pina Cardarelli, Miho Oyasu, Daniel Menezes, Paul Ponath, John Cogswell, Russell Maxwell, Andrew Luksik, Alice Hung, Eileen Kim, Zineb Belcaid, Henry Brem, Drew Pardoll, Michael Lim
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1736.
DOI: https://doi.org/10.1158/1538-7445.AM2018-1736
Published: 01 July 2018
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Journal Articles

Abstract LB-293: IL-2 diphtheria toxin fusion protein with anti-PD1: in mouse B16-F10 melanoma model

Juan Fu, Drew Pardoll, Laurene Cheung
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-293.
DOI: https://doi.org/10.1158/1538-7445.AM2018-LB-293
Published: 01 July 2018
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Journal Articles

Abstract 3843: Autologous resconstitution of human cancer and immune system in vivo

Juan Fu, Rupashree Sen, David L Masica, Rachel Karchin, Drew Pardoll, Young Kim
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3843.
DOI: https://doi.org/10.1158/1538-7445.AM2017-3843
Published: 01 July 2017
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Journal Articles

Abstract 581: Discovery and development of COM701, a therapeutic antibody targeting the novel immune checkpoint PVRIG

Ofer Levy, Chris Chan, Gady Cojocaru, Spencer Liang, Eran Ophir, Sudipto Ganguly, Maya Kotturi, Tal Friedman, Benjamin Murter, Liat Dassa, Ling Leung, Shirley Greenwald, Meir Azulay, Sandeep Kumar, Zoya Alteber, Xiaoyu Pan, Andy Drake, Ran Salomon, Arthur Machlenkin, John Hunter, Zurit Levine, Drew Pardoll, Mark White
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 581.
DOI: https://doi.org/10.1158/1538-7445.AM2017-581
Published: 01 July 2017
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Journal Articles

Abstract 3250: Caspase-1 from MDSC promote MyD88 dependent carcinogenesis that is T-cell independent

Qi Zeng, Jesse R. Qualliotine, Lee Blosser, Drew Pardoll, Young J. Kim
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3250.
DOI: https://doi.org/10.1158/1538-7445.AM2016-3250
Published: 15 July 2016
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Journal Articles

Abstract CT001: Durable, long-term survival in previously treated patients with advanced melanoma (MEL) who received nivolumab (NIVO) monotherapy in a phase I trial

F. Stephen Hodi, Harriet Kluger, Mario Sznol, Richard Carvajal, Donald Lawrence, Michael Atkins, John Powderly, William Sharfman, Igor Puzanov, David Smith, Philip Leming, Evan Lipson, Janis Taube, Robert Anders, Christine Horak, Joel Jiang, David McDermott, Jeffrey Sosman, Julie Brahmer, Drew Pardoll, Suzanne Topalian
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): CT001.
DOI: https://doi.org/10.1158/1538-7445.AM2016-CT001
Published: 15 July 2016
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Journal Articles

Abstract 1312: Transcriptional signatures associated with lack of response to anti-PD-1 therapy in patients with renal cell carcinoma

Maria Libera Ascierto, Tracee McMiller, Alan Berger, Robert A. Anders, Chris Cheadle, Haiying Hu, Charles Drake, Drew Pardoll, Janis Taube, Suzanne L. Topalian
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1312.
DOI: https://doi.org/10.1158/1538-7445.AM2015-1312
Published: 01 August 2015
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Journal Articles

Abstract 5033: Azacitidine pretreatment sensitizes NSCLC cells to interferon-γ

Kai He, Xin Zhang, Ludmila Danilova, Xiaoyu Pan, Julie Brahmer, Drew Pardoll, Malcolm Brock, Stephen Baylin, James Herman, John Wrangle
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5033.
DOI: https://doi.org/10.1158/1538-7445.AM2015-5033
Published: 01 August 2015
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Journal Articles

Abstract 451: The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints

Nicolas Jose Llosa, Michael Cruise, Ada Tam, Elizabeth Wick, Elizabeth Hechenbleikner, Janis Taube, Lee Blosser, Hongni Fan, Hao Wang, Ming Zhang, Brandon Luber, Nickolas Papadopoulos, Kenneth Kinzler, Bert Vogelstein, Cynthia Sears, Robert Anders, Drew Pardoll, Franck Housseau
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 451.
DOI: https://doi.org/10.1158/1538-7445.AM2015-451
Published: 01 August 2015
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Journal Articles

Abstract 2495: STING agonists formulated into cancer vaccines (STINGVAX) can cure established tumor resistant to immune checkpoint blockade by activating NK cells

Young Kim, Drew Pardoll, Juan Fu, Tom Dubensky
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2495.
DOI: https://doi.org/10.1158/1538-7445.AM2015-2495
Published: 01 August 2015
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Journal Articles

Preclinical Evidence That PD1 Blockade Cooperates with Cancer Vaccine TEGVAX to Elicit Regression of Established Tumors

Juan Fu, Ian-James Malm, Deepak K. Kadayakkara, Hy Levitsky, Drew Pardoll, Young J. Kim
Journal: Cancer Research
Series: Author Choice
Cancer Res (2014) 74 (15): 4042–4052.
DOI: https://doi.org/10.1158/0008-5472.CAN-13-2685
Published: 31 July 2014
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Includes: Supplementary data
Journal Articles

Abstract PR9: Granulocyte macrophage colony stimulating factor (GM-CSF) pancreas tumor vaccine in combination with blockade of PD-1 in a preclinical model of pancreatic cancer.

Kevin C. Soares, Kelly Olino, Barish Edil, Donger Zhou, Anthony Wamwea, Ashley Leubner, Richard Schulick, Drew Pardoll, Elizabeth Jaffee, Lei Zheng
Journal: Cancer Research
Cancer Res (2013) 73 (1_Supplement): PR9.
DOI: https://doi.org/10.1158/1538-7445.TUMIMM2012-PR9
Published: 02 April 2014
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Journal Articles

Abstract 3976: PD-1 blockade combined with TEGVAX (TLR agonists-enhanced GVAX) can induce regression of established palpable tumors.

Ian-James Malm, Juan Fu, Drew Pardoll, Young J. Kim
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3976.
DOI: https://doi.org/10.1158/1538-7445.AM2013-3976
Published: 15 April 2013
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Journal Articles

Chemotherapy Acts as an Adjuvant to Convert the Tumor Microenvironment into a Highly Permissive State for Vaccination-Induced Antitumor Immunity

Tae Heung Kang, Chih-Ping Mao, Sung Yong Lee, Alexander Chen, Ji-Hyun Lee, Tae Woo Kim, Ronald D. Alvarez, Richard B.S. Roden, Drew Pardoll, Chien-Fu Hung, T.-C. Wu
Journal: Cancer Research
Cancer Res (2013) 73 (8): 2493–2504.
DOI: https://doi.org/10.1158/0008-5472.CAN-12-4241
Published: 15 April 2013
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Includes: Supplementary data
Journal Articles

Abstract 4619: Epigenetic therapy and sensitization of lung cancer to immunotherapy.

John Wrangle, Wei Wang, Alexander Koch, Hariharan Easwaran, Helai Mohammad, Princy Parsana, Frank Vendetti, Kristen Rodgers, Xiaoyu Pan, Kirsten Harbom, Cynthia Zahnow, Janis Taube, Julie Brahmer, Peter Jones, Suzanne Topalian, Charles Rudin, Malcolm Brock, Drew Pardoll, Stephen Baylin
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4619.
DOI: https://doi.org/10.1158/1538-7445.AM2013-4619
Published: 15 April 2013
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Abstract 4573: STINGVAX - A novel tumor vaccine with cyclic dinucleotides - can induce potent anti-tumor responses in vivo.

Thomas W. Dubensky, Meredith L. Leong, David B. Kanne, Edward E. Lemmens, Ken Metchette, Weiqun Liu, Marcella Fasso, Juan Fu, Joshua J. Woodward, Drew Pardoll, Daniel A. Portnoy, Young J. Kim
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4573.
DOI: https://doi.org/10.1158/1538-7445.AM2013-4573
Published: 15 April 2013
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Journal Articles

A Requirement of STAT3 DNA Binding Precludes Th-1 Immunostimulatory Gene Expression by NF-κB in Tumors

Heehyoung Lee, Jiehui Deng, Hong Xin, Yong Liu, Drew Pardoll, Hua Yu
Journal: Cancer Research
Cancer Res (2011) 71 (11): 3772–3780.
DOI: https://doi.org/10.1158/0008-5472.CAN-10-3304
Published: 31 May 2011
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Includes: Supplementary data
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Abstract LB-456: The intraductal injection of 5-fluorouracil induces immune response to eradicate and prevent breast cancer

Tsuyoshi Mori, Satoshi Wada, Kelly Olino, Walter Weber, Barish Edil, Kristen Meckel, Xiaoyu Pan, Drew Pardoll, Richard Schulick, Saraswati Sukumar, Kiyoshi Yoshimura
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): LB-456.
DOI: https://doi.org/10.1158/1538-7445.AM2011-LB-456
Published: 15 April 2011
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