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Douglas D. Ross
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Journal Articles

Abstract 5498: Prognostic tools to predict the efficacy of anticancer drug treatment targeting Chromatin DNA or enzymes acting on DNA

Narasimharao Nalabothula, Douglas D. Ross, France Carrier
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5498.
https://doi.org/10.1158/1538-7445.AM10-5498
Published: 15 April 2010
View article titled, Abstract 5498: Prognostic tools to predict the efficacy of anticancer drug treatment targeting Chromatin DNA or enzymes acting on DNA
Journal Articles

Abstract 5413: Maximal Power Design and Analysis of Drug Combination Studies: Applications to Vorinostat with Cytosine Arabinoside and Etoposide and Other Combination Studies

Hong-Bin Fang, Douglas D. Ross, Martin J. Edelman, Edward A. Sausville, Wei Li, Ming T. Tan
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5413.
https://doi.org/10.1158/1538-7445.AM10-5413
Published: 15 April 2010
View article titled, Abstract 5413: Maximal Power Design and Analysis of Drug Combination Studies: Applications to Vorinostat with Cytosine Arabinoside and Etoposide and Other Combination Studies
Journal Articles

Novel 5′ Untranslated Region Variants of BCRP mRNA Are Differentially Expressed in Drug-Selected Cancer Cells and in Normal Human Tissues: Implications for Drug Resistance, Tissue-Specific Expression, and Alternative Promoter Usage

Takeo Nakanishi, Kimberly J. Bailey-Dell, Bret A. Hassel, Ken Shiozawa, Daniel M. Sullivan, Joel Turner, Douglas D. Ross
Journal: Cancer Research
Cancer Res (2006) 66 (10): 5007–5011.
https://doi.org/10.1158/0008-5472.CAN-05-4572
Published: 16 May 2006
View article titled, Novel 5′ Untranslated Region Variants of <em>BCRP</em> mRNA Are Differentially Expressed in Drug-Selected Cancer Cells and in Normal Human Tissues: Implications for Drug Resistance, Tissue-Specific Expression, and Alternative Promoter Usage
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Includes: Supplementary data
Journal Articles

Schedule dependent synergy of suberoylanilide hydroxamic acid (SAHA or Vorinostat) in combination with Cytarabine (ara-C) and etoposide in HL-60 human acute myeloid leukemia cells

Ken Shiozawa, Takeo Nakanishi, Ming Tan, Hong-Bin Fang, Martin J. Edelman, Ivana Gojo, Edward Sausville, Douglas D. Ross
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 501.
Published: 15 April 2006
View article titled, Schedule dependent synergy of suberoylanilide hydroxamic acid (SAHA or Vorinostat) in combination with Cytarabine (ara-C) and etoposide in HL-60 human acute myeloid leukemia cells
Journal Articles

BCRP expression is functionally upregulated by epidermal growth factor receptor (EGFR, ErbB1) mediated signaling in human ovarian cancer cell lines, but not in human breast cancer cell lines

Takeo Nakanishi, Ken Shiozawa, Anne W. Hamburger, Douglas D. Ross
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 146.
Published: 15 April 2006
View article titled, BCRP expression is functionally upregulated by epidermal growth factor receptor (EGFR, ErbB1) mediated signaling in human ovarian cancer cell lines, but not in human breast cancer cell lines
Journal Articles

Complex interaction of BCRP/ABCG2 and STI-571 in BCR-ABL positive cells: BCRP-mediated resistance to STI-571 is attenuated by STI-571-induced reduction in BCRP expression

Takeo Nakanishi, Ken Shiozawa, Victoria S. Yang, Douglas D. Ross
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 121.
Published: 01 May 2005
View article titled, Complex interaction of BCRP/ABCG2 and STI-571 in BCR-ABL positive cells: BCRP-mediated resistance to STI-571 is attenuated by STI-571-induced reduction in BCRP expression
Journal Articles

Benzoylphenylurea (BPU) is a substrate for the Breast Cancer Resistance Protein (BCRP/ABCG2) transporter but not P-glycoprotein (Pgp/MDR1/ABCB1)

Tushar S. Garimella, Douglas D. Ross, Noha N. Salama, Martin J. Edelman, Noble Nemieboka, Kenneth S. Bauer
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 119.
Published: 01 April 2004
View article titled, Benzoylphenylurea (BPU) is a substrate for the Breast Cancer Resistance Protein (BCRP/ABCG2) transporter but not P-glycoprotein (Pgp/MDR1/ABCB1)
Journal Articles

Evaluation of the mechanism of BCRP/ABCG2 gene overexpression in drug-selected multidrug resistant cells

Takeo Nakanishi, Yuetong Wei, Bret Hassel, Douglas D. Ross
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 119–120.
Published: 01 April 2004
View article titled, Evaluation of the mechanism of BCRP/ABCG2 gene overexpression in drug-selected multidrug resistant cells
Journal Articles

Identification of a novel estrogen response element in the breast cancer resistance protein gene

P. L. Rachel Ee, Sitharthan Kamalakaran, Debra Tonetti, Xiaolong He, Douglas D. Ross, William T. Beck
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 142.
Published: 01 April 2004
View article titled, Identification of a novel estrogen response element in the breast cancer resistance protein gene
Journal Articles

The stem cell marker (ABCG2) enhances hypoxic cell survival through interactions with heme

Partha C. Krishnamurthy, Douglas D. Ross, Takeo Nakanishi, Kim Bailey-Dell, Sheng Zhou, Kelly E. Mercer, Balazs Sarkadi, Brian P. Sorrentino, John D. Schuetz
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 119.
Published: 01 April 2004
View article titled, The stem cell marker (ABCG2) enhances hypoxic cell survival through interactions with heme
Journal Articles

Identification of a Novel Estrogen Response Element in the Breast Cancer Resistance Protein ( ABCG2 ) Gene

Pui Lai Rachel Ee, Sitharthan Kamalakaran, Debra Tonetti, Xiaolong He, Douglas D. Ross, William T. Beck
Journal: Cancer Research
Cancer Res (2004) 64 (4): 1247–1251.
https://doi.org/10.1158/0008-5472.CAN-03-3583
Published: 18 February 2004
View article titled, Identification of a Novel Estrogen Response Element in the <em>Breast Cancer Resistance Protein</em> ( <em>ABCG2</em> ) Gene
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Journal Articles

Transport of Methotrexate, Methotrexate Polyglutamates, and 17β-Estradiol 17-(β-d-glucuronide) by ABCG2: Effects of Acquired Mutations at R482 on Methotrexate Transport1

Zhe-Sheng Chen, Robert W. Robey, Martin G. Belinsky, Irina Shchaveleva, Xiao-Qin Ren, Yoshikazu Sugimoto, Douglas D. Ross, Susan E. Bates, Gary D. Kruh
Journal: Cancer Research
Cancer Res (2003) 63 (14): 4048–4054.
Published: 21 July 2003
View article titled, Transport of Methotrexate, Methotrexate Polyglutamates, and 17β-Estradiol 17-(β-<sc>d</sc>-glucuronide) by ABCG2: Effects of Acquired Mutations at R482 on Methotrexate Transport1
Open the PDF for Transport of Methotrexate, Methotrexate Polyglutamates, and 17β-Estradiol 17-(β-<sc>d</sc>-glucuronide) by ABCG2: Effects of Acquired Mutations at R482 on Methotrexate Transport1 in another window
Journal Articles

Differential Effects of the Breast Cancer Resistance Protein on the Cellular Accumulation and Cytotoxicity of 9-Aminocamptothecin and 9-Nitrocamptothecin

Rajeev Rajendra, Murugesan K. Gounder, Ahamed Saleem, Jan H. M. Schellens, Douglas D. Ross, Susan E. Bates, Patrick Sinko, Eric H. Rubin
Journal: Cancer Research
Cancer Res (2003) 63 (12): 3228–3233.
Published: 15 June 2003
View article titled, Differential Effects of the Breast Cancer Resistance Protein on the Cellular Accumulation and Cytotoxicity of 9-Aminocamptothecin and 9-Nitrocamptothecin
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Journal Articles

The HER Tyrosine Kinase Inhibitor CI1033 Enhances Cytotoxicity of 7-Ethyl-10-hydroxycamptothecin and Topotecan by Inhibiting Breast Cancer Resistance Protein-mediated Drug Efflux

Charles Erlichman, Scott A. Boerner, Christopher G. Hallgren, Rebecca Spieker, Xiao-Yang Wang, C. David James, George L. Scheffer, Marc Maliepaard, Douglas D. Ross, Keith C. Bible, Scott H. Kaufmann
Journal: Cancer Research
Cancer Res (2001) 61 (2): 739–748.
Published: 01 January 2001
View article titled, The HER Tyrosine Kinase Inhibitor CI1033 Enhances Cytotoxicity of 7-Ethyl-10-hydroxycamptothecin and Topotecan by Inhibiting Breast Cancer Resistance Protein-mediated Drug Efflux
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Journal Articles

Methotrexate Cross-Resistance in a Mitoxantrone-selected Multidrug-resistant MCF7 Breast Cancer Cell Line Is Attributable to Enhanced Energy-dependent Drug Efflux

Erin L. Volk, Kristin Rohde, Myung Rhee, John J. McGuire, L. Austin Doyle, Douglas D. Ross, Erasmus Schneider
Journal: Cancer Research
Cancer Res (2000) 60 (13): 3514–3521.
Published: 01 July 2000
View article titled, Methotrexate Cross-Resistance in a Mitoxantrone-selected Multidrug-resistant MCF7 Breast Cancer Cell Line Is Attributable to Enhanced Energy-dependent Drug Efflux
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Journal Articles

Breast Cancer Resistance Protein Is Localized at the Plasma Membrane in Mitoxantrone- and Topotecan-resistant Cell Lines

George L. Scheffer, Marc Maliepaard, Adriana C. L. M. Pijnenborg, Margôt A. van Gastelen, Mariska C. de Jong, Anouk B. Schroeijers, Dorina M. van der Kolk, John D. Allen, Douglas D. Ross, Paul van der Valk, William S. Dalton, Jan H. M. Schellens, Rik J. Scheper
Journal: Cancer Research
Cancer Res (2000) 60 (10): 2589–2593.
Published: 15 May 2000
View article titled, Breast Cancer Resistance Protein Is Localized at the Plasma Membrane in Mitoxantrone- and Topotecan-resistant Cell Lines
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Journal Articles

Fumitremorgin C Reverses Multidrug Resistance in Cells Transfected with the Breast Cancer Resistance Protein

Sridhar K. Rabindran, Douglas D. Ross, L. Austin Doyle, Weidong Yang, Lee M. Greenberger
Journal: Cancer Research
Cancer Res (2000) 60 (1): 47–50.
Published: 01 January 2000
View article titled, Fumitremorgin C Reverses Multidrug Resistance in Cells Transfected with the Breast Cancer Resistance Protein
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Journal Articles

The 95-Kilodalton Membrane Glycoprotein Overexpressed in Novel Multidrugresistant Breast Cancer Cells Is NCA, the Nonspecific Cross-reacting Antigen of Carcinoembryonic Antigen

Douglas D. Ross, Yongming Gao, Weidong Yang, John Leszyk, John Shively, L. Austin Doyle
Journal: Cancer Research
Cancer Res (1997) 57 (24): 5460–5464.
Published: 01 December 1997
View article titled, The 95-Kilodalton Membrane Glycoprotein Overexpressed in Novel Multidrugresistant Breast Cancer Cells Is NCA, the Nonspecific Cross-reacting Antigen of Carcinoembryonic Antigen
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Journal Articles

H19 Gene Overexpression in Atypical Multidrug-resistant Cells Associated with Expression of a 95-Kilodalton Membrane Glycoprotein

L. Austin Doyle, Weidong Yang, Arun K. Rishi, Yongming Gao, Douglas D. Ross
Journal: Cancer Research
Cancer Res (1996) 56 (13): 2904–2907.
Published: 01 July 1996
View article titled, <em>H19</em> Gene Overexpression in Atypical Multidrug-resistant Cells Associated with Expression of a 95-Kilodalton Membrane Glycoprotein
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Journal Articles

Interaction of N,N′,N″-Triethylenethiophosphoramide and N,N′,N″-Triethylenephosphoramide with Cellular DNA

Noam A. Cohen, Merrill J. Egorin, Stuart W. Snyder, Bimal Ashar, Bruce E. Wietharn, Su-shu Pan, Douglas D. Ross, John Hilton
Journal: Cancer Research
Cancer Res (1991) 51 (16): 4360–4366.
Published: 01 August 1991
View article titled, Interaction of <em>N,N′,N″</em>-Triethylenethiophosphoramide and <em>N,N′,N″</em>-Triethylenephosphoramide with Cellular DNA
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